JP2010523591A - 抗ウイルス処置 - Google Patents

抗ウイルス処置 Download PDF

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Publication number
JP2010523591A
JP2010523591A JP2010502312A JP2010502312A JP2010523591A JP 2010523591 A JP2010523591 A JP 2010523591A JP 2010502312 A JP2010502312 A JP 2010502312A JP 2010502312 A JP2010502312 A JP 2010502312A JP 2010523591 A JP2010523591 A JP 2010523591A
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JP
Japan
Prior art keywords
optionally substituted
virus
compound
compound according
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2010502312A
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English (en)
Japanese (ja)
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JP2010523591A5 (enExample
Inventor
ビシュワナス リンガッパ，
ジェイコブ プラットナー，
コーム ケレアー，
ビバリー フリーマン，
ウィリアム ハンセン，
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Individual
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Individual
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Application filed by Individual filed Critical Individual
Publication of JP2010523591A publication Critical patent/JP2010523591A/ja
Publication of JP2010523591A5 publication Critical patent/JP2010523591A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
JP2010502312A 2007-04-03 2008-04-03 抗ウイルス処置 Pending JP2010523591A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90992807P 2007-04-03 2007-04-03
PCT/US2008/059326 WO2008124550A1 (en) 2007-04-03 2008-04-03 Phenothiazin derivatives for antiviral treatments

Publications (2)

Publication Number Publication Date
JP2010523591A true JP2010523591A (ja) 2010-07-15
JP2010523591A5 JP2010523591A5 (enExample) 2012-05-24

Family

ID=39718949

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010502312A Pending JP2010523591A (ja) 2007-04-03 2008-04-03 抗ウイルス処置

Country Status (7)

Country Link
US (1) US8227459B2 (enExample)
EP (1) EP2137172A1 (enExample)
JP (1) JP2010523591A (enExample)
CN (1) CN101631780A (enExample)
AU (1) AU2008237276A1 (enExample)
CA (1) CA2686513C (enExample)
WO (1) WO2008124550A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2963024B1 (en) * 2009-09-24 2018-07-18 WisTa Laboratories Ltd. Crystalline methylthioninium chloride hydrates - part 2
AU2016202982B2 (en) * 2009-09-24 2017-09-21 TauRx Therapeutics Management Ltd Crystalline methylthionium chloride (methylene blue) hydrates
SG185094A1 (en) * 2010-04-30 2012-12-28 Prostetta Antiviral Inc Antiviral compounds
US8759336B2 (en) 2011-03-17 2014-06-24 Prosetta Antiviral Inc. Antiviral compounds
WO2012135402A1 (en) * 2011-03-29 2012-10-04 Prostetta Antiviral Inc. Antiviral compounds
EP2699241B1 (en) * 2011-04-20 2016-07-27 Prosetta Antiviral Inc. Antiviral compounds
US20120301904A1 (en) 2011-04-26 2012-11-29 Prosetta Antiviral, Inc Multiprotein assemblies
US10153510B2 (en) 2014-06-23 2018-12-11 University Of Kentucky Research Foundation Non-aqueous redox flow batteries including 3,7-perfluoroalkylated phenothiazine derivatives
US9518022B2 (en) * 2014-12-15 2016-12-13 Prosetta Antiviral Inc. Anti-HIV compounds
CN114605267B (zh) * 2022-03-18 2024-02-23 北京格林凯默科技有限公司 2-溴-n,n-二甲基苯胺的制备方法
EP4651874A2 (en) * 2023-02-21 2025-11-26 Prosetta Biosciences, Inc. Phenothiazinyl compounds and uses

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005054217A1 (en) * 2003-11-28 2005-06-16 Photopharmica Limited Developments in biologically active methylene blue derivatives (2)
WO2006032879A2 (en) * 2004-09-23 2006-03-30 Wista Laboratories Ltd. Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc)
WO2007110627A2 (en) * 2006-03-29 2007-10-04 Wista Laboratories Ltd. 3,7-diamino-10h-phenothiazine salts and their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19640758C2 (de) * 1996-10-02 1999-11-04 Rafael Lachky Mittel zur Behandlung von Diskusfischen
GB0113121D0 (en) * 2001-05-30 2001-07-18 Univ Leeds Biologically active photosensitisers
WO2006034219A2 (en) * 2004-09-17 2006-03-30 The General Hospital Corporation Inactivation of microorganisms with multidrug resistance inhibitors and phenothiaziniums
GB0420888D0 (en) * 2004-09-20 2004-10-20 Photopharmica Ltd Compounds and uses

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005054217A1 (en) * 2003-11-28 2005-06-16 Photopharmica Limited Developments in biologically active methylene blue derivatives (2)
WO2006032879A2 (en) * 2004-09-23 2006-03-30 Wista Laboratories Ltd. Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc)
WO2007110627A2 (en) * 2006-03-29 2007-10-04 Wista Laboratories Ltd. 3,7-diamino-10h-phenothiazine salts and their use

Also Published As

Publication number Publication date
US20110178071A1 (en) 2011-07-21
CA2686513C (en) 2017-06-13
EP2137172A1 (en) 2009-12-30
US8227459B2 (en) 2012-07-24
CN101631780A (zh) 2010-01-20
CA2686513A1 (en) 2008-10-16
AU2008237276A1 (en) 2008-10-16
WO2008124550A1 (en) 2008-10-16

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