CN101631780A - 用于抗病毒治疗的吩噻嗪衍生物 - Google Patents

用于抗病毒治疗的吩噻嗪衍生物 Download PDF

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Publication number
CN101631780A
CN101631780A CN200880008338A CN200880008338A CN101631780A CN 101631780 A CN101631780 A CN 101631780A CN 200880008338 A CN200880008338 A CN 200880008338A CN 200880008338 A CN200880008338 A CN 200880008338A CN 101631780 A CN101631780 A CN 101631780A
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CN
China
Prior art keywords
compound
virus
replaces
optional
hydrogen
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Pending
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CN200880008338A
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English (en)
Chinese (zh)
Inventor
V·林格帕
J·普莱特尼尔
C·克莱尔
B·弗瑞曼
W·汉森
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Prosetta Bioconformatics Inc
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Prosetta Bioconformatics Inc
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Publication date
Application filed by Prosetta Bioconformatics Inc filed Critical Prosetta Bioconformatics Inc
Publication of CN101631780A publication Critical patent/CN101631780A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN200880008338A 2007-04-03 2008-04-03 用于抗病毒治疗的吩噻嗪衍生物 Pending CN101631780A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90992807P 2007-04-03 2007-04-03
US60/909,928 2007-04-03

Publications (1)

Publication Number Publication Date
CN101631780A true CN101631780A (zh) 2010-01-20

Family

ID=39718949

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880008338A Pending CN101631780A (zh) 2007-04-03 2008-04-03 用于抗病毒治疗的吩噻嗪衍生物

Country Status (7)

Country Link
US (1) US8227459B2 (enExample)
EP (1) EP2137172A1 (enExample)
JP (1) JP2010523591A (enExample)
CN (1) CN101631780A (enExample)
AU (1) AU2008237276A1 (enExample)
CA (1) CA2686513C (enExample)
WO (1) WO2008124550A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2689029T3 (es) * 2009-09-24 2018-11-08 Wista Laboratories Ltd. Hidratos de cloruro de metiltioninio cristalinos - Parte 2
AU2016202982B2 (en) * 2009-09-24 2017-09-21 TauRx Therapeutics Management Ltd Crystalline methylthionium chloride (methylene blue) hydrates
US8785434B2 (en) 2010-04-30 2014-07-22 Prosetta Antiviral Inc. Antiviral compounds
US8828986B2 (en) 2011-04-20 2014-09-09 Prosetta Antiviral Inc. Antiviral compounds
US8759336B2 (en) 2011-03-17 2014-06-24 Prosetta Antiviral Inc. Antiviral compounds
WO2012135402A1 (en) * 2011-03-29 2012-10-04 Prostetta Antiviral Inc. Antiviral compounds
US20120301904A1 (en) 2011-04-26 2012-11-29 Prosetta Antiviral, Inc Multiprotein assemblies
US10153510B2 (en) 2014-06-23 2018-12-11 University Of Kentucky Research Foundation Non-aqueous redox flow batteries including 3,7-perfluoroalkylated phenothiazine derivatives
WO2016100391A1 (en) * 2014-12-15 2016-06-23 Prosetta Antiviral, Inc. 2-phenethenyltetrahydro isoquinolines useful as anti-hiv compounds
CN114605267B (zh) * 2022-03-18 2024-02-23 北京格林凯默科技有限公司 2-溴-n,n-二甲基苯胺的制备方法
US20240300940A1 (en) * 2023-02-21 2024-09-12 Prosetta Biosciences, Inc. Phenothiazinyl Compounds and Uses

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19640758C2 (de) * 1996-10-02 1999-11-04 Rafael Lachky Mittel zur Behandlung von Diskusfischen
GB0113121D0 (en) * 2001-05-30 2001-07-18 Univ Leeds Biologically active photosensitisers
AU2004295148A1 (en) * 2003-11-28 2005-06-16 Photopharmica Limited Developments in biologically active methylene blue derivatives (2)
US20080166304A1 (en) * 2004-09-17 2008-07-10 The General Hospital Corpoartion Inactivation of Microorganisms With Multidrug Resistance Inhibitors and Phenothiaziniums
GB0420888D0 (en) * 2004-09-20 2004-10-20 Photopharmica Ltd Compounds and uses
PT1799662E (pt) * 2004-09-23 2013-07-09 Wista Lab Ltd Métodos de síntese química e purificação de compostos de diaminofenotiazínio incluindo cloreto de metiltionínio (mtc)
CN109384741B (zh) * 2006-03-29 2023-01-06 维斯塔实验室有限公司 3,7-二氨基-10h-吩噻嗪化合物盐及其用途

Also Published As

Publication number Publication date
CA2686513A1 (en) 2008-10-16
WO2008124550A1 (en) 2008-10-16
US20110178071A1 (en) 2011-07-21
EP2137172A1 (en) 2009-12-30
JP2010523591A (ja) 2010-07-15
US8227459B2 (en) 2012-07-24
CA2686513C (en) 2017-06-13
AU2008237276A1 (en) 2008-10-16

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20100120