AU2008237276A1 - Phenothiazin derivatives for antiviral treatments - Google Patents

Phenothiazin derivatives for antiviral treatments Download PDF

Info

Publication number
AU2008237276A1
AU2008237276A1 AU2008237276A AU2008237276A AU2008237276A1 AU 2008237276 A1 AU2008237276 A1 AU 2008237276A1 AU 2008237276 A AU2008237276 A AU 2008237276A AU 2008237276 A AU2008237276 A AU 2008237276A AU 2008237276 A1 AU2008237276 A1 AU 2008237276A1
Authority
AU
Australia
Prior art keywords
compound
optionally substituted
virus
group
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2008237276A
Other languages
English (en)
Inventor
Beverly Freeman
William Hansen
Colm Kelleher
Vishwanath Lingappa
Jacob Plattner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prosetta Bioconformatics Inc
Original Assignee
Prosetta Bioconformatics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prosetta Bioconformatics Inc filed Critical Prosetta Bioconformatics Inc
Publication of AU2008237276A1 publication Critical patent/AU2008237276A1/en
Assigned to Prosetta Bioconformatics, Inc. reassignment Prosetta Bioconformatics, Inc. Alteration of Name(s) of Applicant(s) under S113 Assignors: PROSETTA CORPORATION
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2008237276A 2007-04-03 2008-04-03 Phenothiazin derivatives for antiviral treatments Abandoned AU2008237276A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90992807P 2007-04-03 2007-04-03
US60/909,928 2007-04-03
PCT/US2008/059326 WO2008124550A1 (en) 2007-04-03 2008-04-03 Phenothiazin derivatives for antiviral treatments

Publications (1)

Publication Number Publication Date
AU2008237276A1 true AU2008237276A1 (en) 2008-10-16

Family

ID=39718949

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008237276A Abandoned AU2008237276A1 (en) 2007-04-03 2008-04-03 Phenothiazin derivatives for antiviral treatments

Country Status (7)

Country Link
US (1) US8227459B2 (enExample)
EP (1) EP2137172A1 (enExample)
JP (1) JP2010523591A (enExample)
CN (1) CN101631780A (enExample)
AU (1) AU2008237276A1 (enExample)
CA (1) CA2686513C (enExample)
WO (1) WO2008124550A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016202982B2 (en) * 2009-09-24 2017-09-21 TauRx Therapeutics Management Ltd Crystalline methylthionium chloride (methylene blue) hydrates
KR20170061177A (ko) * 2009-09-24 2017-06-02 위스타 레보레이토리스 리미티드 결정질 메틸티오니늄 클로라이드（메틸렌 블루） 수화물
US8785434B2 (en) 2010-04-30 2014-07-22 Prosetta Antiviral Inc. Antiviral compounds
US8828986B2 (en) 2011-04-20 2014-09-09 Prosetta Antiviral Inc. Antiviral compounds
US8809317B2 (en) * 2011-03-29 2014-08-19 Prosetta Antiviral Inc. Antiviral compounds
WO2012125983A1 (en) 2011-03-17 2012-09-20 Prosetta Antiviral Inc. Antiviral treatments
US20120301904A1 (en) 2011-04-26 2012-11-29 Prosetta Antiviral, Inc Multiprotein assemblies
US10153510B2 (en) 2014-06-23 2018-12-11 University Of Kentucky Research Foundation Non-aqueous redox flow batteries including 3,7-perfluoroalkylated phenothiazine derivatives
WO2016100391A1 (en) * 2014-12-15 2016-06-23 Prosetta Antiviral, Inc. 2-phenethenyltetrahydro isoquinolines useful as anti-hiv compounds
CN114605267B (zh) * 2022-03-18 2024-02-23 北京格林凯默科技有限公司 2-溴-n,n-二甲基苯胺的制备方法
US20240300940A1 (en) * 2023-02-21 2024-09-12 Prosetta Biosciences, Inc. Phenothiazinyl Compounds and Uses

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19640758C2 (de) * 1996-10-02 1999-11-04 Rafael Lachky Mittel zur Behandlung von Diskusfischen
GB0113121D0 (en) * 2001-05-30 2001-07-18 Univ Leeds Biologically active photosensitisers
BRPI0416928A (pt) * 2003-11-28 2007-01-16 Photopharmica Ltd desenvolvimento de derivados biologicamente ativos de azul de metileno
US20080166304A1 (en) * 2004-09-17 2008-07-10 The General Hospital Corpoartion Inactivation of Microorganisms With Multidrug Resistance Inhibitors and Phenothiaziniums
GB0420888D0 (en) * 2004-09-20 2004-10-20 Photopharmica Ltd Compounds and uses
WO2006032879A2 (en) * 2004-09-23 2006-03-30 Wista Laboratories Ltd. Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc)
CN104119294B (zh) * 2006-03-29 2018-10-30 维斯塔实验室有限公司 3,7-二氨基-10h-吩噻嗪化合物的制备方法

Also Published As

Publication number Publication date
WO2008124550A1 (en) 2008-10-16
CA2686513C (en) 2017-06-13
CA2686513A1 (en) 2008-10-16
US8227459B2 (en) 2012-07-24
JP2010523591A (ja) 2010-07-15
US20110178071A1 (en) 2011-07-21
CN101631780A (zh) 2010-01-20
EP2137172A1 (en) 2009-12-30

Similar Documents

Publication Publication Date Title
CA2686513C (en) Diamino-benzothiazine derivatives as antiviral agents
US8759336B2 (en) Antiviral compounds
EP2585073B1 (en) Antiviral compounds
US8809317B2 (en) Antiviral compounds
MX2011006244A (es) Nuevos peptidos de 4-amino-4-oxobutanoilo como inhibidores de replica viral.
RU2011130833A (ru) Антивирусные соединения
Muhamad et al. Antiviral actions of flavanoid-derived compounds on dengue virus type-2
US20210283160A1 (en) Viral inhibition
EP2699241B1 (en) Antiviral compounds
CN110237074A (zh) 贝尼地平在制备预防和/或治疗布尼亚病毒感染性疾病药物中的应用
AU748836B2 (en) Methods for preventing and treating pestivirus infection and associated diseases
CN106880630A (zh) Retro‑2cycl及相关衍生物的用途
CN113546076A (zh) 维替泊芬在制备抗新型冠状病毒SARS-CoV-2药物中的用途
Herrmann Jr et al. Comparison of the antiviral effects of substituted benzimidazoles and guanidine in vitro and in vivo
Gendrel et al. One-dose treatment with pefloxacin for infection due to multidrug-resistant Shigella dysenteriae type 1 in Burundi
CN115721654A (zh) 藜芦碱在制备抗冠状病毒的药物中的应用
CN117865993B (zh) 一种aak1抑制剂及其制备和应用
US6541472B1 (en) Compounds, compositions and methods for preventing and treating pestivirus infection and associated diseases
Giranda et al. Rhinoviral capsid-binding inhibitors: structural basis for understanding rhinoviral biology and for drug design
CN121971463A (zh) 依托泊苷在制备抗狂犬病病毒药物中的应用
Bossi et al. EUROPEAN GUIDELINES FOR THE CLINICAL MANAGEMENT OF VIRAL ENCEPHALITIS AND BIOTERRORISM-RELATED VIRAL ENCEPHALITIS
CN107714713A (zh) 台勾霉素衍生物在制备治疗登革病毒感染引起的相关疾病和/或症状的药物中的应用
TH124666A (th) สไปโรไซคลิก โพรลีน และการใช้สารเหล่านั้นในการรักษาการติดเชื้อ hcv

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted