JP2010522218A5 - - Google Patents
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- Publication number
- JP2010522218A5 JP2010522218A5 JP2010500035A JP2010500035A JP2010522218A5 JP 2010522218 A5 JP2010522218 A5 JP 2010522218A5 JP 2010500035 A JP2010500035 A JP 2010500035A JP 2010500035 A JP2010500035 A JP 2010500035A JP 2010522218 A5 JP2010522218 A5 JP 2010522218A5
- Authority
- JP
- Japan
- Prior art keywords
- dihydro
- oxo
- carbonyl
- amino
- cyclopropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92001807P | 2007-03-26 | 2007-03-26 | |
| PCT/CA2008/000561 WO2008116304A1 (en) | 2007-03-26 | 2008-03-25 | Naphthalene and quinoline sulfonylurea derivatives as ep4 receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010522218A JP2010522218A (ja) | 2010-07-01 |
| JP2010522218A5 true JP2010522218A5 (enExample) | 2011-05-06 |
Family
ID=39787996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500035A Pending JP2010522218A (ja) | 2007-03-26 | 2008-03-25 | Ｅｐ４受容体アンタゴニストとしてのナフタレン及びキノリンスルホニル尿素誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8003661B2 (enExample) |
| EP (1) | EP2125724B1 (enExample) |
| JP (1) | JP2010522218A (enExample) |
| CN (1) | CN101636385B (enExample) |
| AU (1) | AU2008232265B2 (enExample) |
| CA (1) | CA2681146A1 (enExample) |
| WO (1) | WO2008116304A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2011003166A (es) | 2008-09-25 | 2011-04-27 | Merck Frosst Canada Ltd | Derivados de sulfonilurea beta-carbolina como antagonistas del receptor ep4. |
| WO2010087425A1 (ja) | 2009-01-30 | 2010-08-05 | 国立大学法人京都大学 | 前立腺癌の進行抑制剤および進行抑制方法 |
| WO2014143591A1 (en) | 2013-03-12 | 2014-09-18 | Allergan, Inc. | Inhibition of neovascularization by simultaneous inhibition of prostanoid ip and ep4 receptors |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| PE20191787A1 (es) | 2017-05-18 | 2019-12-24 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituidos |
| KR102612140B1 (ko) | 2017-05-18 | 2023-12-08 | 이도르시아 파마슈티컬스 리미티드 | 피리미딘 유도체 |
| AR111808A1 (es) | 2017-05-18 | 2019-08-21 | Idorsia Pharmaceuticals Ltd | Derivados de pirimidina como moduladores del receptor de pge2 |
| EA201992676A1 (ru) | 2017-05-18 | 2020-05-06 | Идорсия Фармасьютиклз Лтд | Фенильные производные в качестве модуляторов pge2 рецепторов |
| US11325899B2 (en) | 2017-05-18 | 2022-05-10 | Idorsia Pharmaceuticals Ltd | Benzofurane and benzothiophene derivatives as PGE2 receptor modulators |
| JP7816164B2 (ja) | 2020-11-13 | 2026-02-18 | 小野薬品工業株式会社 | Ｅｐ４拮抗薬と免疫チェックポイント阻害物質との併用によるがん治療 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9417532D0 (en) | 1994-08-31 | 1994-10-19 | Zeneca Ltd | Aromatic compounds |
| GB9420557D0 (en) | 1994-10-12 | 1994-11-30 | Zeneca Ltd | Aromatic compounds |
| US5834468A (en) | 1995-07-07 | 1998-11-10 | Zeneca Limited | Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists |
| HN2001000224A (es) * | 2000-10-19 | 2002-06-13 | Pfizer | Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos. |
| GB0031302D0 (en) * | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Napthalene derivatives |
| JP2005532291A (ja) * | 2002-04-12 | 2005-10-27 | ファイザー株式会社 | 抗炎症薬および鎮痛薬としてのピラゾール化合物 |
| ATE533766T1 (de) * | 2005-05-19 | 2011-12-15 | Merck Canada Inc | Chinolinderivate als ep4-antagonisten |
-
2008
- 2008-03-25 CN CN2008800089997A patent/CN101636385B/zh not_active Expired - Fee Related
- 2008-03-25 AU AU2008232265A patent/AU2008232265B2/en not_active Ceased
- 2008-03-25 WO PCT/CA2008/000561 patent/WO2008116304A1/en not_active Ceased
- 2008-03-25 EP EP08733664.0A patent/EP2125724B1/en active Active
- 2008-03-25 CA CA002681146A patent/CA2681146A1/en not_active Abandoned
- 2008-03-25 US US12/529,271 patent/US8003661B2/en active Active
- 2008-03-25 JP JP2010500035A patent/JP2010522218A/ja active Pending
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