JP2010522218A5 - - Google Patents
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- Publication number
- JP2010522218A5 JP2010522218A5 JP2010500035A JP2010500035A JP2010522218A5 JP 2010522218 A5 JP2010522218 A5 JP 2010522218A5 JP 2010500035 A JP2010500035 A JP 2010500035A JP 2010500035 A JP2010500035 A JP 2010500035A JP 2010522218 A5 JP2010522218 A5 JP 2010522218A5
- Authority
- JP
- Japan
- Prior art keywords
- dihydro
- oxo
- carbonyl
- amino
- cyclopropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92001807P | 2007-03-26 | 2007-03-26 | |
| PCT/CA2008/000561 WO2008116304A1 (en) | 2007-03-26 | 2008-03-25 | Naphthalene and quinoline sulfonylurea derivatives as ep4 receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010522218A JP2010522218A (ja) | 2010-07-01 |
| JP2010522218A5 true JP2010522218A5 (enExample) | 2011-05-06 |
Family
ID=39787996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500035A Pending JP2010522218A (ja) | 2007-03-26 | 2008-03-25 | Ｅｐ４受容体アンタゴニストとしてのナフタレン及びキノリンスルホニル尿素誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8003661B2 (enExample) |
| EP (1) | EP2125724B1 (enExample) |
| JP (1) | JP2010522218A (enExample) |
| CN (1) | CN101636385B (enExample) |
| AU (1) | AU2008232265B2 (enExample) |
| CA (1) | CA2681146A1 (enExample) |
| WO (1) | WO2008116304A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009295308A1 (en) * | 2008-09-25 | 2010-04-01 | Merck Canada Inc. | Beta-carboline sulphonylurea derivatives as EP4 receptor antagonists |
| US20110287112A1 (en) | 2009-01-30 | 2011-11-24 | Ono Pharmaceutical Co., Ltd. | Prostate cancer progression inhibitor and progression inhibition method |
| WO2014143591A1 (en) | 2013-03-12 | 2014-09-18 | Allergan, Inc. | Inhibition of neovascularization by simultaneous inhibition of prostanoid ip and ep4 receptors |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| AU2018268311B2 (en) | 2017-05-18 | 2022-02-10 | Idorsia Pharmaceuticals Ltd | Pyrimidine derivatives as PGE2 receptor modulators |
| TW201900180A (zh) | 2017-05-18 | 2019-01-01 | 瑞士商愛杜西亞製藥有限公司 | 嘧啶衍生物 |
| CN110612296A (zh) | 2017-05-18 | 2019-12-24 | 爱杜西亚药品有限公司 | 作为pge2受体调节剂的苯基衍生物 |
| JP7093791B2 (ja) | 2017-05-18 | 2022-06-30 | イドーシア ファーマシューティカルズ リミテッド | Ｐｇｅ２レセプター調節剤としてのベンゾフラン及びベンゾチオフェン誘導体 |
| MX394108B (es) | 2017-05-18 | 2025-03-21 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituidos. |
| KR20230107228A (ko) | 2020-11-13 | 2023-07-14 | 오노 야꾸힝 고교 가부시키가이샤 | Ep4 길항약과 면역 체크포인트 저해 물질의 병용에 의한 암 치료 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9417532D0 (en) | 1994-08-31 | 1994-10-19 | Zeneca Ltd | Aromatic compounds |
| GB9420557D0 (en) | 1994-10-12 | 1994-11-30 | Zeneca Ltd | Aromatic compounds |
| US5834468A (en) | 1995-07-07 | 1998-11-10 | Zeneca Limited | Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists |
| HN2001000224A (es) * | 2000-10-19 | 2002-06-13 | Pfizer | Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos. |
| GB0031302D0 (en) * | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Napthalene derivatives |
| CA2482382A1 (en) * | 2002-04-12 | 2003-10-23 | Pfizer Inc. | Pyrazole compounds as anti-inflammatory and analgesic agents |
| US8013159B2 (en) * | 2005-05-19 | 2011-09-06 | Merck Canada Inc. | Quinoline derivatives as EP4 antagonists |
-
2008
- 2008-03-25 AU AU2008232265A patent/AU2008232265B2/en not_active Ceased
- 2008-03-25 US US12/529,271 patent/US8003661B2/en active Active
- 2008-03-25 EP EP08733664.0A patent/EP2125724B1/en active Active
- 2008-03-25 CA CA002681146A patent/CA2681146A1/en not_active Abandoned
- 2008-03-25 JP JP2010500035A patent/JP2010522218A/ja active Pending
- 2008-03-25 WO PCT/CA2008/000561 patent/WO2008116304A1/en not_active Ceased
- 2008-03-25 CN CN2008800089997A patent/CN101636385B/zh not_active Expired - Fee Related
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