JP2010521495A - 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強 - Google Patents

漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強 Download PDF

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JP2010521495A
JP2010521495A JP2009553828A JP2009553828A JP2010521495A JP 2010521495 A JP2010521495 A JP 2010521495A JP 2009553828 A JP2009553828 A JP 2009553828A JP 2009553828 A JP2009553828 A JP 2009553828A JP 2010521495 A JP2010521495 A JP 2010521495A
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xaa
formulation
peptide
assembling
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JP2010521495A5 (en:Method
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ラトリッジ エリス−ベーンク，
スティーブン リチャード ケリー，
テレンス ダブリュー． ノーチ，
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アーチ セラピューティクス， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
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  • Immunology (AREA)
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  • Molecular Biology (AREA)
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  • Heart & Thoracic Surgery (AREA)
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JP2009553828A 2007-03-14 2008-03-14 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強 Withdrawn JP2010521495A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89487207P 2007-03-14 2007-03-14
PCT/US2008/057104 WO2008113030A2 (en) 2007-03-14 2008-03-14 Treatment of leaky or damaged tight junctions and enhancing extracellular matrix

Related Child Applications (1)

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JP2013133118A Division JP5860437B2 (ja) 2007-03-14 2013-06-25 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強

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JP2010521495A true JP2010521495A (ja) 2010-06-24
JP2010521495A5 JP2010521495A5 (en:Method) 2011-04-28

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JP2009553828A Withdrawn JP2010521495A (ja) 2007-03-14 2008-03-14 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強
JP2013133118A Expired - Fee Related JP5860437B2 (ja) 2007-03-14 2013-06-25 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強
JP2014227726A Expired - Fee Related JP6112621B2 (ja) 2007-03-14 2014-11-10 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強
JP2017043479A Pending JP2017105833A (ja) 2007-03-14 2017-03-08 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強

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JP2013133118A Expired - Fee Related JP5860437B2 (ja) 2007-03-14 2013-06-25 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強
JP2014227726A Expired - Fee Related JP6112621B2 (ja) 2007-03-14 2014-11-10 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強
JP2017043479A Pending JP2017105833A (ja) 2007-03-14 2017-03-08 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強

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US (2) US9415084B2 (en:Method)
EP (1) EP2146733B1 (en:Method)
JP (4) JP2010521495A (en:Method)
CA (1) CA2680824C (en:Method)
DK (1) DK2146733T3 (en:Method)
ES (1) ES2854674T3 (en:Method)
WO (1) WO2008113030A2 (en:Method)

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WO2014162906A1 (ja) * 2013-03-30 2014-10-09 株式会社糖鎖工学研究所 糖鎖－ポリペプチド複合体
WO2015053338A1 (ja) * 2013-10-08 2015-04-16 学校法人東京理科大学 カチオン性ペプチドおよびそれを含む医薬組成物
WO2015145797A1 (ja) * 2014-03-28 2015-10-01 大塚化学株式会社 止血用医薬組成物
JP2016528018A (ja) * 2013-08-22 2016-09-15 アーチ・バイオサージェリー・インコーポレイテッド 流体の移動を制御するための移植可能なメッシュ
WO2017104723A1 (ja) * 2015-12-18 2017-06-22 株式会社スリー・ディー・マトリックス 止血用組成物、および、止血用組成物を用いた止血方法
WO2024128081A1 (ja) * 2022-12-16 2024-06-20 東亞合成株式会社 合成ペプチド及び構築物

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JP2021506815A (ja) 2017-12-15 2021-02-22 株式会社スリー・ディー・マトリックス 界面活性ペプチドナノ構造および薬物送達における使用
JPWO2019139126A1 (ja) * 2018-01-11 2021-04-08 国立大学法人 東京大学 Ｎｔｃｐ阻害剤
CN112165954A (zh) * 2018-03-23 2021-01-01 阿奇生物外科有限公司 用于治疗眼病的sap和拟肽
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WO2025226888A1 (en) * 2024-04-26 2025-10-30 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Ecm-derived injectable embolic for permanent treatment of cerebral aneurysms

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