JP2010520273A - ピロリルヘプタン酸誘導体の新規な結晶形態 - Google Patents

ピロリルヘプタン酸誘導体の新規な結晶形態 Download PDF

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Publication number
JP2010520273A
JP2010520273A JP2009552583A JP2009552583A JP2010520273A JP 2010520273 A JP2010520273 A JP 2010520273A JP 2009552583 A JP2009552583 A JP 2009552583A JP 2009552583 A JP2009552583 A JP 2009552583A JP 2010520273 A JP2010520273 A JP 2010520273A
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crystalline form
formula
compound
alcohol
hydrate
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JP2010520273A5 (enExample
Inventor
キム、ムン、スン
ヨ、ム、ヒ
リー、ジェ、コル
キム、ヨン、ジク
パク、ソン、ジン
チェ、ジュン、ホ
スン、シ、ヤン
リム、ホン、ギュ
チャ、テ、ウォン
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ドン・ア・ファーム・カンパニー・リミテッド
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Publication of JP2010520273A publication Critical patent/JP2010520273A/ja
Publication of JP2010520273A5 publication Critical patent/JP2010520273A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
JP2009552583A 2007-03-02 2008-03-03 ピロリルヘプタン酸誘導体の新規な結晶形態 Pending JP2010520273A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20070020999 2007-03-02
KR1020080019764A KR101012917B1 (ko) 2007-03-02 2008-03-03 피롤 헵탄산 화합물의 신규한 결정형
PCT/KR2008/001218 WO2008108572A1 (en) 2007-03-02 2008-03-03 Novel crystal forms of pyrrolylheptanoic acid derivatives

Publications (2)

Publication Number Publication Date
JP2010520273A true JP2010520273A (ja) 2010-06-10
JP2010520273A5 JP2010520273A5 (enExample) 2012-06-14

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ID=40020978

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JP2009552583A Pending JP2010520273A (ja) 2007-03-02 2008-03-03 ピロリルヘプタン酸誘導体の新規な結晶形態

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Country Link
US (1) US7915302B2 (enExample)
EP (1) EP2132171A4 (enExample)
JP (1) JP2010520273A (enExample)
KR (1) KR101012917B1 (enExample)
CN (1) CN101657419A (enExample)
CA (1) CA2679317A1 (enExample)
RU (1) RU2421445C1 (enExample)
WO (1) WO2008108572A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012031130A (ja) * 2010-07-28 2012-02-16 Kyongbo Pharm Co Ltd アトルバスタチンヘミカルシウム塩の新規な結晶形、その水和物、及びその製造方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011219437A (ja) * 2010-04-14 2011-11-04 Towa Yakuhin Kk 結晶性形態ｔｗ−１のアトルバスタチンヘミカルシウム水和物とその製造方法
RU2555360C2 (ru) * 2012-11-06 2015-07-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ определения воды в координационных соединениях

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004514694A (ja) * 2000-11-30 2004-05-20 テバ　ファーマシューティカル　インダストリーズ　リミティド アトルバスタチンヘミカルシウムの新規結晶形態およびその調製方法ならびに他の形態の新規調製方法
WO2004050618A2 (en) * 2002-11-28 2004-06-17 Teva Pharmaceutical Industries Ltd. Crystalline form f of atorvastatin hemi-calcium salt
JP2005501032A (ja) * 2001-06-29 2005-01-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 結晶型［Ｒ−（Ｒ＊，Ｒ＊）］−２−（４−フルオロフェニル）−β，δ−ジヒドロキシ−５−（１−メチルエチル）−３−フェニル−４−［（フェニルアミノ）カルボニル］−１Ｈ−ピロール−１−ヘプタン酸カルシウム塩（２：１）（アトロバスタチン）
WO2005090301A1 (en) * 2004-03-17 2005-09-29 Ranbaxy Laboratories Limited Crystalline form of atorvastatin hemi calcium
JP2006503024A (ja) * 2002-09-03 2006-01-26 モレペン、ラボラトリーズ、リミテッド Ｖｉ型アトルバスタチンカルシウムまたはその水和物
WO2006048894A1 (en) * 2004-11-05 2006-05-11 Morepen Laboratories Limited Novel crystalline forms of atorvastatin calcium and processes for preparing them.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI94339C (fi) * 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
DE69634054T2 (de) * 1995-07-17 2005-12-08 Warner-Lambert Co. Kristalline (R-(R*, R*))-2-(4-Fluorophenyl)-β, δ-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-1H-Pyrrol-1-Heptancarbonsäure Hemi Calcium Salz (Atorvastatin)
DE19951107A1 (de) * 1999-10-23 2001-05-23 Zahnradfabrik Friedrichshafen Steuerung eines Automatgetriebes eines Kraftfahrzeuges
SI1535613T1 (sl) * 1999-11-17 2010-12-31 Teva Pharma Postopek za pripravo polimorfne oblike atorvastatin kalcija
SI20425A (sl) * 1999-12-10 2001-06-30 LEK tovarna farmacevtskih in kemi�nih izdelkov d.d. Priprava amorfnega atorvastatina
US7501450B2 (en) * 2000-11-30 2009-03-10 Teva Pharaceutical Industries Ltd. Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
WO2003070702A1 (en) * 2002-02-15 2003-08-28 Teva Pharmaceutical Industries Ltd. Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation, as well as novel processes for preparing atorvastatin hemi-calcium forms i, viii and ix

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004514694A (ja) * 2000-11-30 2004-05-20 テバ　ファーマシューティカル　インダストリーズ　リミティド アトルバスタチンヘミカルシウムの新規結晶形態およびその調製方法ならびに他の形態の新規調製方法
JP2005501032A (ja) * 2001-06-29 2005-01-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 結晶型［Ｒ−（Ｒ＊，Ｒ＊）］−２−（４−フルオロフェニル）−β，δ−ジヒドロキシ−５−（１−メチルエチル）−３−フェニル−４−［（フェニルアミノ）カルボニル］−１Ｈ−ピロール−１−ヘプタン酸カルシウム塩（２：１）（アトロバスタチン）
JP2006503024A (ja) * 2002-09-03 2006-01-26 モレペン、ラボラトリーズ、リミテッド Ｖｉ型アトルバスタチンカルシウムまたはその水和物
WO2004050618A2 (en) * 2002-11-28 2004-06-17 Teva Pharmaceutical Industries Ltd. Crystalline form f of atorvastatin hemi-calcium salt
WO2005090301A1 (en) * 2004-03-17 2005-09-29 Ranbaxy Laboratories Limited Crystalline form of atorvastatin hemi calcium
WO2006048894A1 (en) * 2004-11-05 2006-05-11 Morepen Laboratories Limited Novel crystalline forms of atorvastatin calcium and processes for preparing them.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012031130A (ja) * 2010-07-28 2012-02-16 Kyongbo Pharm Co Ltd アトルバスタチンヘミカルシウム塩の新規な結晶形、その水和物、及びその製造方法

Also Published As

Publication number Publication date
RU2421445C1 (ru) 2011-06-20
EP2132171A1 (en) 2009-12-16
KR20080080959A (ko) 2008-09-05
KR101012917B1 (ko) 2011-02-08
US20100113556A1 (en) 2010-05-06
US7915302B2 (en) 2011-03-29
EP2132171A4 (en) 2010-11-17
CA2679317A1 (en) 2008-09-12
CN101657419A (zh) 2010-02-24
WO2008108572A1 (en) 2008-09-12
RU2009136427A (ru) 2011-04-10

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