RU2421445C1 - Новые кристаллические формы производных пирролилгептановой кислоты - Google Patents

Новые кристаллические формы производных пирролилгептановой кислоты Download PDF

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Publication number
RU2421445C1
RU2421445C1 RU2009136427/04A RU2009136427A RU2421445C1 RU 2421445 C1 RU2421445 C1 RU 2421445C1 RU 2009136427/04 A RU2009136427/04 A RU 2009136427/04A RU 2009136427 A RU2009136427 A RU 2009136427A RU 2421445 C1 RU2421445 C1 RU 2421445C1
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RU
Russia
Prior art keywords
crystalline form
formula
alcohol
compound
hydrate
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RU2009136427/04A
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English (en)
Russian (ru)
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RU2009136427A (ru
Inventor
Моон Сунг КИМ (KR)
Моон Сунг КИМ
Моо Хи ЙОО (KR)
Моо Хи ЙОО
Дзае Кеол РХЕЕ (KR)
Дзае Кеол РХЕЕ
Йонг Дзик КИМ (KR)
Йонг Дзик КИМ
Сеонг Дзин ПАРК (KR)
Сеонг Дзин ПАРК
Дзун Хо ЧОЙ (KR)
Дзун Хо ЧОЙ
Си Янг СУНГ (KR)
Си Янг СУНГ
Хонг Гиу ЛИМ (KR)
Хонг Гиу ЛИМ
Дае Вон ЧА (KR)
Дае Вон ЧА
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Донг-А Фарм. Ко., Лтд.
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Publication of RU2009136427A publication Critical patent/RU2009136427A/ru
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
RU2009136427/04A 2007-03-02 2008-03-03 Новые кристаллические формы производных пирролилгептановой кислоты RU2421445C1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR20070020999 2007-03-02
KR10-2007-0020999 2007-03-02
KR1020080019764A KR101012917B1 (ko) 2007-03-02 2008-03-03 피롤 헵탄산 화합물의 신규한 결정형
KR10-2008-0019764 2008-03-03

Publications (2)

Publication Number Publication Date
RU2009136427A RU2009136427A (ru) 2011-04-10
RU2421445C1 true RU2421445C1 (ru) 2011-06-20

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RU2009136427/04A RU2421445C1 (ru) 2007-03-02 2008-03-03 Новые кристаллические формы производных пирролилгептановой кислоты

Country Status (8)

Country Link
US (1) US7915302B2 (enExample)
EP (1) EP2132171A4 (enExample)
JP (1) JP2010520273A (enExample)
KR (1) KR101012917B1 (enExample)
CN (1) CN101657419A (enExample)
CA (1) CA2679317A1 (enExample)
RU (1) RU2421445C1 (enExample)
WO (1) WO2008108572A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2555360C2 (ru) * 2012-11-06 2015-07-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ определения воды в координационных соединениях

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011219437A (ja) * 2010-04-14 2011-11-04 Towa Yakuhin Kk 結晶性形態ｔｗ−１のアトルバスタチンヘミカルシウム水和物とその製造方法
KR20120011249A (ko) 2010-07-28 2012-02-07 주식회사 경보제약 아토바스타틴 헤미칼슘염의 신규한 결정형, 이의 수화물, 및 그의 제조방법

Citations (4)

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WO2002036384A1 (de) * 1999-10-23 2002-05-10 Zf Friedrichshafen Ag Steuerung eines automatgetriebes eines kraftfahrzeuges
WO2003070702A1 (en) * 2002-02-15 2003-08-28 Teva Pharmaceutical Industries Ltd. Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation, as well as novel processes for preparing atorvastatin hemi-calcium forms i, viii and ix
WO2004043918A2 (en) * 2002-11-12 2004-05-27 Teva Pharmaceutical Industries Ltd. Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
RU2247113C2 (ru) * 1999-12-10 2005-02-27 Лек Фармасьютикал Энд Кемикал Компани Д.Д. Способ получения аморфного аторвастатина

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FI94339C (fi) * 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
DE69634054T2 (de) * 1995-07-17 2005-12-08 Warner-Lambert Co. Kristalline (R-(R*, R*))-2-(4-Fluorophenyl)-β, δ-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-1H-Pyrrol-1-Heptancarbonsäure Hemi Calcium Salz (Atorvastatin)
SI1535613T1 (sl) * 1999-11-17 2010-12-31 Teva Pharma Postopek za pripravo polimorfne oblike atorvastatin kalcija
IL156055A0 (en) 2000-11-30 2003-12-23 Teva Pharma Novel crystal forms of atorvastatin hemi calcium and processes for their preparation as well as novel processes for preparing other forms
EP1423364B1 (en) * 2001-06-29 2015-11-04 Warner-Lambert Company LLC Crystalline forms of [r-(r*,r*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid calcium salt (2:1) (atorvastatin)
EP1562583A1 (en) * 2002-09-03 2005-08-17 Morepen Laboratories Ltd. Atorvastatin calcium form vi or hydrates thereof
CA2508871C (en) * 2002-11-28 2008-09-09 Teva Pharmaceutical Industries Ltd. Crystalline form f of atorvastatin hemi-calcium salt
WO2005090301A1 (en) * 2004-03-17 2005-09-29 Ranbaxy Laboratories Limited Crystalline form of atorvastatin hemi calcium
WO2006048894A1 (en) * 2004-11-05 2006-05-11 Morepen Laboratories Limited Novel crystalline forms of atorvastatin calcium and processes for preparing them.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002036384A1 (de) * 1999-10-23 2002-05-10 Zf Friedrichshafen Ag Steuerung eines automatgetriebes eines kraftfahrzeuges
RU2247113C2 (ru) * 1999-12-10 2005-02-27 Лек Фармасьютикал Энд Кемикал Компани Д.Д. Способ получения аморфного аторвастатина
WO2003070702A1 (en) * 2002-02-15 2003-08-28 Teva Pharmaceutical Industries Ltd. Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation, as well as novel processes for preparing atorvastatin hemi-calcium forms i, viii and ix
WO2004043918A2 (en) * 2002-11-12 2004-05-27 Teva Pharmaceutical Industries Ltd. Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
RU 2304139 c2, 10.08.2007. *
WO 2002/043732 a1, 06.06.2002. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2555360C2 (ru) * 2012-11-06 2015-07-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ определения воды в координационных соединениях

Also Published As

Publication number Publication date
EP2132171A1 (en) 2009-12-16
KR20080080959A (ko) 2008-09-05
KR101012917B1 (ko) 2011-02-08
US20100113556A1 (en) 2010-05-06
US7915302B2 (en) 2011-03-29
EP2132171A4 (en) 2010-11-17
CA2679317A1 (en) 2008-09-12
CN101657419A (zh) 2010-02-24
WO2008108572A1 (en) 2008-09-12
RU2009136427A (ru) 2011-04-10
JP2010520273A (ja) 2010-06-10

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Effective date: 20150304