JP2010515707A5 - - Google Patents
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- Publication number
- JP2010515707A5 JP2010515707A5 JP2009545182A JP2009545182A JP2010515707A5 JP 2010515707 A5 JP2010515707 A5 JP 2010515707A5 JP 2009545182 A JP2009545182 A JP 2009545182A JP 2009545182 A JP2009545182 A JP 2009545182A JP 2010515707 A5 JP2010515707 A5 JP 2010515707A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- molecule
- use according
- nucleic acid
- dbait32hc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07300728.8 | 2007-01-12 | ||
| EP07300728A EP1944369A1 (en) | 2007-01-12 | 2007-01-12 | Dbait and its standalone uses thereof |
| PCT/EP2008/050265 WO2008084087A2 (en) | 2007-01-12 | 2008-01-11 | Dbait and its standalone uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010515707A JP2010515707A (ja) | 2010-05-13 |
| JP2010515707A5 true JP2010515707A5 (enExample) | 2011-02-17 |
| JP5462632B2 JP5462632B2 (ja) | 2014-04-02 |
Family
ID=38515555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009545182A Expired - Fee Related JP5462632B2 (ja) | 2007-01-12 | 2008-01-11 | Ｄｂａｉｔおよびその単独使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8093366B2 (enExample) |
| EP (2) | EP1944369A1 (enExample) |
| JP (1) | JP5462632B2 (enExample) |
| CN (1) | CN101622351B (enExample) |
| AU (1) | AU2008204486C1 (enExample) |
| CA (1) | CA2673972C (enExample) |
| EA (1) | EA016053B1 (enExample) |
| WO (1) | WO2008084087A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3135301T3 (en) * | 2010-06-22 | 2018-06-25 | Onxeo | OPTIMIZED IN VIVO DELIVERY SYSTEM WITH ENDOSOMOLYTIC SUBSTANCES FOR NUCLEIC ACID CONJUGATES |
| AU2015202211B2 (en) * | 2010-06-22 | 2016-09-01 | Centre National De La Recherche Scientifique | Optimized in vivo delivery system with endosomolytic agents for nucleic acid conjugates |
| EP2527440A1 (en) * | 2011-05-27 | 2012-11-28 | Institut Curie | Cancer treatment by combining DNA molecules mimicking double strand breaks with hyperthermia |
| AU2016296905B2 (en) | 2015-07-23 | 2018-07-05 | Centre National De La Recherche Scientifique | Use of a combination of Dbait molecule and parp inhibitors to treat cancer |
| JP6949859B2 (ja) * | 2016-03-01 | 2021-10-13 | オンクセオＯｎｘｅｏ | Ｄｂａｉｔ分子の全身投与によるガンの処置 |
| WO2017186882A1 (en) * | 2016-04-29 | 2017-11-02 | Onxeo | A method of predicting a response to an anti-tumor treatment by means of signal interfering dna molecules |
| WO2018162439A1 (en) | 2017-03-08 | 2018-09-13 | Onxeo | New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule |
| KR20200028392A (ko) * | 2017-06-12 | 2020-03-16 | 유니버시티 오브 마이애미 | 질환의 치료를 위한 sting-의존성 활성화제 |
| CN107793468A (zh) * | 2017-06-26 | 2018-03-13 | 上海悦良生物科技有限公司 | 一种检测dna损伤的方法 |
| EP3461488A1 (en) | 2017-09-27 | 2019-04-03 | Onxeo | Combination of a dbait molecule and a hdac inhibitor for treating cancer |
| JP7534218B2 (ja) * | 2018-03-13 | 2024-08-14 | ヴァレリオ・セラピューティクス | がんの治療における獲得耐性に対抗するｄｂａｉｔ分子 |
| CN109321585B (zh) * | 2018-09-30 | 2021-08-06 | 山东大学 | 一种利用t4脱氧核糖核酸连接酶提高原核微生物诱变育种效率的方法 |
| AU2019408408A1 (en) | 2018-12-21 | 2021-06-03 | Valerio Therapeutics | New conjugated nucleic acid molecules and their uses |
| AU2020242287A1 (en) | 2019-03-21 | 2021-09-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A Dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| ES3041492T3 (en) | 2019-12-18 | 2025-11-12 | Stinginn Llc | Substituted 1,2, 4-triazoles and methods of use |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| US20230095192A1 (en) * | 2020-03-03 | 2023-03-30 | University Of Washington | Synthetic agonists of dna-pk and their use |
| US11897888B1 (en) | 2020-04-30 | 2024-02-13 | Stinginn Llc | Small molecular inhibitors of sting signaling compositions and methods of use |
| TW202210633A (zh) | 2020-06-05 | 2022-03-16 | 法商昂席歐公司 | 用於治療癌症之dbait分子與kras抑制劑的組合 |
| TW202214857A (zh) | 2020-06-19 | 2022-04-16 | 法商昂席歐公司 | 新型結合核酸分子及其用途 |
| EP4448761A1 (en) | 2021-12-16 | 2024-10-23 | Valerio Therapeutics | New conjugated nucleic acid molecules and their uses |
| WO2024240858A1 (en) | 2023-05-23 | 2024-11-28 | Valerio Therapeutics | Protac molecules directed against dna damage repair system and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1526177A1 (en) * | 2003-10-24 | 2005-04-27 | Institut Curie | Nucleic acids useful for triggering tumor cell lethality |
| JP2005247807A (ja) * | 2004-03-08 | 2005-09-15 | Japan Science & Technology Agency | Ｎｓａｉｄを利用した癌治療用組成物 |
| US20060276423A1 (en) * | 2005-04-18 | 2006-12-07 | Rachel Altura | Survivin-directed RNA interference-compositions and methods |
-
2007
- 2007-01-12 EP EP07300728A patent/EP1944369A1/en not_active Withdrawn
-
2008
- 2008-01-11 EP EP08701411.4A patent/EP2102343B1/en active Active
- 2008-01-11 US US12/520,961 patent/US8093366B2/en active Active
- 2008-01-11 CA CA2673972A patent/CA2673972C/en active Active
- 2008-01-11 JP JP2009545182A patent/JP5462632B2/ja not_active Expired - Fee Related
- 2008-01-11 EA EA200900989A patent/EA016053B1/ru not_active IP Right Cessation
- 2008-01-11 AU AU2008204486A patent/AU2008204486C1/en not_active Ceased
- 2008-01-11 WO PCT/EP2008/050265 patent/WO2008084087A2/en not_active Ceased
- 2008-01-11 CN CN200880002041.7A patent/CN101622351B/zh active Active
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