JP2010515707A5 - - Google Patents

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Publication number
JP2010515707A5
JP2010515707A5 JP2009545182A JP2009545182A JP2010515707A5 JP 2010515707 A5 JP2010515707 A5 JP 2010515707A5 JP 2009545182 A JP2009545182 A JP 2009545182A JP 2009545182 A JP2009545182 A JP 2009545182A JP 2010515707 A5 JP2010515707 A5 JP 2010515707A5
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JP
Japan
Prior art keywords
seq
molecule
use according
nucleic acid
dbait32hc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009545182A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010515707A (ja
JP5462632B2 (ja
Filing date
Publication date
Priority claimed from EP07300728A external-priority patent/EP1944369A1/en
Application filed filed Critical
Publication of JP2010515707A publication Critical patent/JP2010515707A/ja
Publication of JP2010515707A5 publication Critical patent/JP2010515707A5/ja
Application granted granted Critical
Publication of JP5462632B2 publication Critical patent/JP5462632B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009545182A 2007-01-12 2008-01-11 Dbaitおよびその単独使用 Expired - Fee Related JP5462632B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07300728A EP1944369A1 (en) 2007-01-12 2007-01-12 Dbait and its standalone uses thereof
EP07300728.8 2007-01-12
PCT/EP2008/050265 WO2008084087A2 (en) 2007-01-12 2008-01-11 Dbait and its standalone uses thereof

Publications (3)

Publication Number Publication Date
JP2010515707A JP2010515707A (ja) 2010-05-13
JP2010515707A5 true JP2010515707A5 (OSRAM) 2011-02-17
JP5462632B2 JP5462632B2 (ja) 2014-04-02

Family

ID=38515555

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009545182A Expired - Fee Related JP5462632B2 (ja) 2007-01-12 2008-01-11 Dbaitおよびその単独使用

Country Status (8)

Country Link
US (1) US8093366B2 (OSRAM)
EP (2) EP1944369A1 (OSRAM)
JP (1) JP5462632B2 (OSRAM)
CN (1) CN101622351B (OSRAM)
AU (1) AU2008204486C1 (OSRAM)
CA (1) CA2673972C (OSRAM)
EA (1) EA016053B1 (OSRAM)
WO (1) WO2008084087A2 (OSRAM)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015202211B2 (en) * 2010-06-22 2016-09-01 Centre National De La Recherche Scientifique Optimized in vivo delivery system with endosomolytic agents for nucleic acid conjugates
EP3689381A1 (en) 2010-06-22 2020-08-05 Onxeo Optimized in vivo delivery system with endosomolytic agents for nucleic acid conjugates
EP2527440A1 (en) 2011-05-27 2012-11-28 Institut Curie Cancer treatment by combining DNA molecules mimicking double strand breaks with hyperthermia
EP3325623B3 (en) 2015-07-23 2021-01-20 Institut Curie Use of a combination of dbait molecule and parp inhibitors to treat cancer
KR20220127360A (ko) * 2016-03-01 2022-09-19 옹쎄오 Dbait 분자의 전신 투여에 의한 암 치료법
WO2017186882A1 (en) * 2016-04-29 2017-11-02 Onxeo A method of predicting a response to an anti-tumor treatment by means of signal interfering dna molecules
WO2018162439A1 (en) 2017-03-08 2018-09-13 Onxeo New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule
KR20200028392A (ko) * 2017-06-12 2020-03-16 유니버시티 오브 마이애미 질환의 치료를 위한 sting-의존성 활성화제
CN107793468A (zh) * 2017-06-26 2018-03-13 上海悦良生物科技有限公司 一种检测dna损伤的方法
EP3461488A1 (en) 2017-09-27 2019-04-03 Onxeo Combination of a dbait molecule and a hdac inhibitor for treating cancer
WO2019175132A1 (en) * 2018-03-13 2019-09-19 Onxeo A dbait molecule against acquired resistance in the treatment of cancer
CN109321585B (zh) * 2018-09-30 2021-08-06 山东大学 一种利用t4脱氧核糖核酸连接酶提高原核微生物诱变育种效率的方法
MX2021007271A (es) 2018-12-21 2021-07-15 Onxeo Nuevas moleculas de acido nucleico conjugado y sus usos.
JP2022526713A (ja) * 2019-03-21 2022-05-26 オンクセオ がんの処置のための、キナーゼ阻害剤と組み合わせたDbait分子
EP4075980B1 (en) 2019-12-18 2025-07-23 Stinginn LLC Substituted 1,2, 4-triazoles and methods of use
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
WO2021178295A1 (en) * 2020-03-03 2021-09-10 University Of Washington Synthetic agonists of dna-pk and their use
US11897888B1 (en) 2020-04-30 2024-02-13 Stinginn Llc Small molecular inhibitors of sting signaling compositions and methods of use
TW202210633A (zh) 2020-06-05 2022-03-16 法商昂席歐公司 用於治療癌症之dbait分子與kras抑制劑的組合
TW202214857A (zh) 2020-06-19 2022-04-16 法商昂席歐公司 新型結合核酸分子及其用途
CN118660964A (zh) 2021-12-16 2024-09-17 瓦莱里奥治疗公司 新型缀合核酸分子及其用途
WO2024240858A1 (en) 2023-05-23 2024-11-28 Valerio Therapeutics Protac molecules directed against dna damage repair system and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1526177A1 (en) * 2003-10-24 2005-04-27 Institut Curie Nucleic acids useful for triggering tumor cell lethality
JP2005247807A (ja) * 2004-03-08 2005-09-15 Japan Science & Technology Agency Nsaidを利用した癌治療用組成物
US20060276423A1 (en) * 2005-04-18 2006-12-07 Rachel Altura Survivin-directed RNA interference-compositions and methods

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