JP2010514703A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010514703A5 JP2010514703A5 JP2009543292A JP2009543292A JP2010514703A5 JP 2010514703 A5 JP2010514703 A5 JP 2010514703A5 JP 2009543292 A JP2009543292 A JP 2009543292A JP 2009543292 A JP2009543292 A JP 2009543292A JP 2010514703 A5 JP2010514703 A5 JP 2010514703A5
- Authority
- JP
- Japan
- Prior art keywords
- feed solution
- chamber
- surfactant
- product
- reintroduced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims description 26
- 239000012527 feed solution Substances 0.000 claims description 18
- 238000001035 drying Methods 0.000 claims description 17
- 239000004094 surface-active agent Substances 0.000 claims description 10
- 239000007789 gas Substances 0.000 claims description 8
- 239000002904 solvent Substances 0.000 claims description 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 6
- 239000012530 fluid Substances 0.000 claims description 5
- 229920000642 polymer Polymers 0.000 claims description 5
- 239000011859 microparticle Substances 0.000 claims description 4
- 239000002245 particle Substances 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 3
- 229910052757 nitrogen Inorganic materials 0.000 claims description 3
- 238000000926 separation method Methods 0.000 claims description 3
- 238000001694 spray drying Methods 0.000 claims description 3
- 239000007921 spray Substances 0.000 claims description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 6
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical group ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 claims 6
- 238000005243 fluidization Methods 0.000 claims 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical group [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 3
- 229930003427 Vitamin E Natural products 0.000 claims 3
- 150000004347 all-trans-retinol derivatives Chemical class 0.000 claims 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 3
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 3
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 3
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims 3
- 229940046009 vitamin E Drugs 0.000 claims 3
- 235000019165 vitamin E Nutrition 0.000 claims 3
- 239000011709 vitamin E Substances 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 2
- 238000007599 discharging Methods 0.000 claims 1
- 239000010419 fine particle Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 description 3
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87169506P | 2006-12-22 | 2006-12-22 | |
| US97384507P | 2007-09-20 | 2007-09-20 | |
| PCT/US2007/088837 WO2008080167A2 (en) | 2006-12-22 | 2007-12-26 | Fluidized spray drying |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010514703A JP2010514703A (ja) | 2010-05-06 |
| JP2010514703A5 true JP2010514703A5 (https=) | 2011-06-30 |
Family
ID=39563267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009543292A Pending JP2010514703A (ja) | 2006-12-22 | 2007-12-26 | 流動床スプレー乾燥法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100011610A1 (https=) |
| EP (1) | EP2101803A4 (https=) |
| JP (1) | JP2010514703A (https=) |
| AU (1) | AU2007336516B2 (https=) |
| CA (1) | CA2673539A1 (https=) |
| MX (1) | MX2009006806A (https=) |
| NZ (1) | NZ577820A (https=) |
| WO (1) | WO2008080167A2 (https=) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8399615B2 (en) | 2005-08-19 | 2013-03-19 | Vertex Pharmaceuticals Incorporated | Processes and intermediates |
| EP3219705B1 (en) | 2005-12-28 | 2020-03-11 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions of the amorphous form of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
| EP1870649A1 (en) * | 2006-06-20 | 2007-12-26 | Octapharma AG | Lyophilisation targetting defined residual moisture by limited desorption energy levels |
| US7716849B1 (en) * | 2006-07-12 | 2010-05-18 | Neil Hicks | Glove dryer |
| DK2097148T3 (da) * | 2006-12-22 | 2010-10-18 | Gea Process Engineering As | Fremgangsmåde til styring af et spraytørreapparat ved styring af en indløbsluftstrømningshastighed, og et spraytørreapparat |
| US7908765B2 (en) * | 2006-12-22 | 2011-03-22 | Collette Nv | Continuous granulating and drying apparatus |
| MX2011001782A (es) | 2008-08-13 | 2012-02-08 | Vertex Pharma | Composicion farmaceutica y su administracion. |
| US12458635B2 (en) | 2008-08-13 | 2025-11-04 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| WO2010117976A1 (en) | 2009-04-09 | 2010-10-14 | Entegrion, Inc | Spray-dried blood products and methods of making same |
| JPWO2010123010A1 (ja) * | 2009-04-21 | 2012-10-25 | 株式会社松井製作所 | プラスチック成形材料の減圧乾燥装置 |
| US20110142885A1 (en) | 2009-09-16 | 2011-06-16 | Velico Medical, Inc. | Spray-dried human plasma |
| US8936689B1 (en) * | 2009-09-24 | 2015-01-20 | The United States Of America As Represented By The Secretary Of The Army | Insensitive explosives and process therefore |
| AU2011210795A1 (en) | 2010-01-29 | 2012-08-02 | Vertex Pharmaceuticals Incorporated | Therapies for treating Hepatitis C virus infection |
| US8397592B2 (en) | 2010-02-19 | 2013-03-19 | Vertex Pharmaceuticals, Inc. | Systems and methods for inline sampling |
| EP2593105A1 (en) | 2010-07-14 | 2013-05-22 | Vertex Pharmaceuticals Incorporated | Palatable pharmaceutical composition comprising vx-950 |
| WO2012054870A2 (en) | 2010-10-21 | 2012-04-26 | Vertex Pharmaceuticals Incorporated | Biomarkers for hcv infected patients |
| US9382672B2 (en) | 2010-12-06 | 2016-07-05 | Astec, Inc. | Apparatus and method for dryer performance optimization system |
| US8863404B1 (en) * | 2010-12-06 | 2014-10-21 | Astec, Inc. | Apparatus and method for dryer performance optimization system |
| US20130195797A1 (en) * | 2012-01-31 | 2013-08-01 | Vertex Pharmaceuticals Incorporated | High potency formulations of vx-950 |
| JP2015511583A (ja) | 2012-02-27 | 2015-04-20 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | 薬学的組成物およびその投与 |
| TW201402153A (zh) * | 2012-04-04 | 2014-01-16 | Lonza Ag | 菸鹼醯胺粉末和其製備方法及裝置 |
| WO2014015217A1 (en) | 2012-07-19 | 2014-01-23 | Vertex Pharmaceuticals Incorporated | Biomarkers for hcv infected patients |
| CN102788488A (zh) * | 2012-08-03 | 2012-11-21 | 梁首强 | 一种高速离心干燥方法及实施该方法的干燥系统 |
| US9744240B2 (en) * | 2012-09-27 | 2017-08-29 | Basf Se | Storage-stable dust-free homogeneous particulate formulation comprising at least one water-soluble vitamin E-derivative and at least one hydrophilic polymer |
| US9789063B2 (en) * | 2012-09-27 | 2017-10-17 | Basf Se | Storage-stable dust-free homogeneous particulate formulation |
| CN102937290B (zh) * | 2012-11-21 | 2015-08-26 | 中国东方电气集团有限公司 | 一种外置床式双流化床防止锅炉沾污的系统 |
| CN104681425B (zh) * | 2013-11-29 | 2018-07-31 | 细美事有限公司 | 基板处理装置及基板处理方法 |
| BR122023021436A2 (pt) * | 2014-03-14 | 2023-12-12 | Les Laboratoires Servier | Formas cristalinas e composição farmacêutica de compostos terapeuticamente ativos |
| PT107568B (pt) | 2014-03-31 | 2018-11-05 | Hovione Farm S A | Processo de secagem por atomização para a produção de pós com propriedades melhoradas. |
| US20160016181A1 (en) * | 2014-05-02 | 2016-01-21 | Kenneth D Lathrop | Bean roaster with controllable fluid loft and electrostatic collector |
| US9561184B2 (en) | 2014-09-19 | 2017-02-07 | Velico Medical, Inc. | Methods and systems for multi-stage drying of plasma |
| WO2016083617A1 (en) * | 2014-11-28 | 2016-06-02 | Chr. Hansen A/S | Spray freezing |
| EP3257574A1 (en) * | 2016-06-15 | 2017-12-20 | Clariant International Ltd | Method for producing a particle-shaped material |
| CN109126495B (zh) * | 2018-07-09 | 2021-06-01 | 山东微研生物科技有限公司 | 一种节能环保型维生素b2干燥装置 |
| US11794161B1 (en) | 2018-11-21 | 2023-10-24 | Trucapsol, Llc | Reduced permeability microcapsules |
| US11571674B1 (en) | 2019-03-28 | 2023-02-07 | Trucapsol Llc | Environmentally biodegradable microcapsules |
| US11542392B1 (en) | 2019-04-18 | 2023-01-03 | Trucapsol Llc | Multifunctional particle additive for enhancement of toughness and degradation in biodegradable polymers |
| WO2021104619A1 (de) | 2019-11-27 | 2021-06-03 | Symrise Ag | Partikuläre erzeugnisse und verfahren zu deren herstellung |
| US11484857B2 (en) | 2020-01-30 | 2022-11-01 | Trucapsol Llc | Environmentally biodegradable microcapsules |
| US12302933B2 (en) | 2021-06-25 | 2025-05-20 | Trucapsol Llc | Flavor delivery system |
| US12187829B2 (en) | 2021-08-12 | 2025-01-07 | Trucapsol Llc | Environmentally biodegradable microcapsules |
| US11878280B2 (en) | 2022-04-19 | 2024-01-23 | Trucapsol Llc | Microcapsules comprising natural materials |
| US12571587B2 (en) * | 2022-09-15 | 2026-03-10 | Velico Medical, Inc. | Finishing apparatus for a spray drying system |
| US11998861B2 (en) | 2022-09-15 | 2024-06-04 | Velico Medical, Inc. | Usability of a disposable for a spray drying plasma system |
| US11975274B2 (en) | 2022-09-15 | 2024-05-07 | Velico Medical, Inc. | Blood plasma product |
| US12539355B2 (en) * | 2022-09-15 | 2026-02-03 | Velico Medical, Inc. | Dryer for a spray drying system |
| US11841189B1 (en) | 2022-09-15 | 2023-12-12 | Velico Medical, Inc. | Disposable for a spray drying system |
| US12246266B2 (en) | 2022-09-15 | 2025-03-11 | Velico Medical, Inc. | Disposable for a spray drying system |
| US12083447B2 (en) | 2022-09-15 | 2024-09-10 | Velico Medical, Inc. | Alignment of a disposable for a spray drying plasma system |
| WO2024059770A1 (en) | 2022-09-15 | 2024-03-21 | Velico Medical, Inc. | Rapid spray drying system |
| US12246093B2 (en) | 2022-09-15 | 2025-03-11 | Velico Medical, Inc. | Methods for making spray dried plasma |
| US11904288B1 (en) | 2023-02-13 | 2024-02-20 | Trucapsol Llc | Environmentally biodegradable microcapsules |
| US11969491B1 (en) | 2023-02-22 | 2024-04-30 | Trucapsol Llc | pH triggered release particle |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK157053B (da) * | 1982-06-14 | 1989-11-06 | Niro Atomizer As | Fremgangsmaade til fremstilling af et agglomereret, pulverformet maelkeprodukt |
| JPH09505516A (ja) * | 1993-11-17 | 1997-06-03 | ニロ・ホールディング・アー／エス | 凝集塊粉体を製造するための噴霧乾燥方法及び装置 |
| NL1000611C2 (nl) * | 1995-06-20 | 1996-12-23 | Stork Friesland Bv | Inrichting, alsmede werkwijze voor het bereiden van een gesproeidroogd produkt. |
| ATE364374T1 (de) * | 1997-08-11 | 2007-07-15 | Pfizer Prod Inc | Feste pharmazeutische dispersionen mit erhöhter bioverfügbarkeit |
| ES2306646T3 (es) * | 1999-02-09 | 2008-11-16 | Pfizer Products Inc. | Composiciones de farmacos basicos con biodisponibilidad incrementada. |
| US6223455B1 (en) * | 1999-05-03 | 2001-05-01 | Acusphere, Inc. | Spray drying apparatus and methods of use |
| JP2000334332A (ja) * | 1999-05-27 | 2000-12-05 | Kyocera Corp | 噴霧乾燥装置 |
| US20010053791A1 (en) * | 2000-03-16 | 2001-12-20 | Babcock Walter C. | Glycogen phosphorylase inhibitor |
| KR20120039763A (ko) * | 2004-06-08 | 2012-04-25 | 버텍스 파마슈티칼스 인코포레이티드 | 약학 조성물 |
| TWI428125B (zh) * | 2006-03-20 | 2014-03-01 | Vertex Pharma | 對包括vx-950之藥物實施噴霧乾燥之方法及由此方法製備之產物 |
-
2007
- 2007-04-11 MX MX2009006806A patent/MX2009006806A/es not_active Application Discontinuation
- 2007-12-26 CA CA002673539A patent/CA2673539A1/en not_active Abandoned
- 2007-12-26 NZ NZ577820A patent/NZ577820A/en not_active IP Right Cessation
- 2007-12-26 WO PCT/US2007/088837 patent/WO2008080167A2/en not_active Ceased
- 2007-12-26 JP JP2009543292A patent/JP2010514703A/ja active Pending
- 2007-12-26 EP EP07866017.2A patent/EP2101803A4/en not_active Withdrawn
- 2007-12-26 AU AU2007336516A patent/AU2007336516B2/en not_active Ceased
-
2009
- 2009-06-22 US US12/488,754 patent/US20100011610A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010514703A5 (https=) | ||
| Cal et al. | Spray drying technique. I: Hardware and process parameters | |
| Santos et al. | Spray drying: an overview | |
| US10918603B2 (en) | Spray drying process for production of powders with enhanced properties | |
| DK2834217T3 (en) | NICOTINAMIDE POWDER AND PROCEDURE AND PREPARATION FOR PREPARING THEREOF | |
| CN100500275C (zh) | 使用喷雾干燥器和内连气流粉碎机制备粒子的方法和设备 | |
| Manu et al. | Spray drying in pharmaceutical industry: A review | |
| Jadhav et al. | A critical review on developments in drying technologies for enhanced stability and bioavailability of pharmaceuticals | |
| CN101730580A (zh) | 用于包衣固体颗粒的流化床设备 | |
| JP2019532068A (ja) | 噴霧乾燥組成物の製造方法及び噴霧乾燥装置 | |
| Binesh et al. | Microencapsulation: spray drying | |
| Hirjau et al. | Pelletization techniques used in pharmaceutical fields | |
| CN108463213A (zh) | 可吸入扎鲁司特颗粒的制备 | |
| Ferreira et al. | Spray-drying for the formulation of oral drug delivery systems | |
| Aundhia et al. | Spray Drying in the pharmaceuticaul Industry-A Review | |
| US12357956B2 (en) | Particle coating method | |
| Negi et al. | Engineering Inhalable Therapeutic Particles: Conventional and Emerging Approaches. Pharmaceutics 2023, 15, 2706 | |
| Çelik et al. | 161 Spray Drying and Pharmaceutical Applications | |
| Solanki | 21 Encapsulation Process in Granulation Technology |