CA2673539A1 - Fluidized spray drying - Google Patents

Fluidized spray drying Download PDF

Info

Publication number
CA2673539A1
CA2673539A1 CA002673539A CA2673539A CA2673539A1 CA 2673539 A1 CA2673539 A1 CA 2673539A1 CA 002673539 A CA002673539 A CA 002673539A CA 2673539 A CA2673539 A CA 2673539A CA 2673539 A1 CA2673539 A1 CA 2673539A1
Authority
CA
Canada
Prior art keywords
polymer
polymers
drug
feed solution
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002673539A
Other languages
English (en)
French (fr)
Inventor
Kevin John Bittorf
Jeffrey P. Katstra
Filipe Gaspar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vertex Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2673539A1 publication Critical patent/CA2673539A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00Drying solid materials or objects by processes involving the application of heat
    • F26B3/02Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • F26B3/10Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it
    • F26B3/12Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it in the form of a spray, i.e. sprayed or dispersed emulsions or suspensions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B21/00Arrangements for supplying or controlling air or other gases for drying solid materials or objects
    • F26B21/40Arrangements for supplying or controlling air or other gases for drying solid materials or objects using gases other than air
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00Drying solid materials or objects by processes involving the application of heat
    • F26B3/02Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • F26B3/06Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour flowing through the materials or objects to be dried
    • F26B3/08Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour flowing through the materials or objects to be dried so as to loosen them, e.g. to form a fluidised bed

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Drying Of Solid Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Supports Or Holders For Household Use (AREA)
CA002673539A 2006-12-22 2007-12-26 Fluidized spray drying Abandoned CA2673539A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US87169506P 2006-12-22 2006-12-22
US60/871,695 2006-12-22
US97384507P 2007-09-20 2007-09-20
US60/973,845 2007-09-20
PCT/US2007/088837 WO2008080167A2 (en) 2006-12-22 2007-12-26 Fluidized spray drying

Publications (1)

Publication Number Publication Date
CA2673539A1 true CA2673539A1 (en) 2008-07-03

Family

ID=39563267

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002673539A Abandoned CA2673539A1 (en) 2006-12-22 2007-12-26 Fluidized spray drying

Country Status (8)

Country Link
US (1) US20100011610A1 (https=)
EP (1) EP2101803A4 (https=)
JP (1) JP2010514703A (https=)
AU (1) AU2007336516B2 (https=)
CA (1) CA2673539A1 (https=)
MX (1) MX2009006806A (https=)
NZ (1) NZ577820A (https=)
WO (1) WO2008080167A2 (https=)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8399615B2 (en) 2005-08-19 2013-03-19 Vertex Pharmaceuticals Incorporated Processes and intermediates
WO2007079139A2 (en) 2005-12-28 2007-07-12 Vertex Pharmaceuticals, Inc. Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
EP1870649A1 (en) * 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
US7716849B1 (en) * 2006-07-12 2010-05-18 Neil Hicks Glove dryer
WO2008077399A1 (en) * 2006-12-22 2008-07-03 Gea Process Engineering A/S A method of controlling a spray dryer apparatus by regulating an inlet air flow rate, and a spray dryer apparatus
US7908765B2 (en) * 2006-12-22 2011-03-22 Collette Nv Continuous granulating and drying apparatus
HRP20180328T1 (hr) 2008-08-13 2018-04-20 Vertex Pharmaceuticals Inc. FARMACEUTSKI PRIPRAVAK N-[2,4-bis(1,1-DIMETILETIL)-5-HIDROKSIFENIL]-1,4-DIHIDRO-4-OKSOKINOLIN-3-KARBOKSAMIDA I NJEGOVO DAVANJE
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
US12458635B2 (en) 2008-08-13 2025-11-04 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
BRPI1006722A2 (pt) 2009-04-09 2017-10-10 Entegrion Inc "método de preparação de hemoderivados desidratado, hemoderivados desidratados, bandagem ou auxílio cirúrgico, método para a preparação de plaquetas sanguíneas fixas desidratadas, plaquetas sanguíneas fixas desidratadas, método para o tratamento de um paciente que sofre de um distúrbio sanguíneo e plaquetas de sangue fixas secas por atomização tendo geometria com cavidades esféricas"
JPWO2010123010A1 (ja) * 2009-04-21 2012-10-25 株式会社松井製作所 プラスチック成形材料の減圧乾燥装置
WO2011035062A2 (en) 2009-09-16 2011-03-24 Velico Medical, Inc. Spray dried human plasma
US8936689B1 (en) * 2009-09-24 2015-01-20 The United States Of America As Represented By The Secretary Of The Army Insensitive explosives and process therefore
RU2012136824A (ru) 2010-01-29 2014-03-10 Вертекс Фармасьютикалз Инкорпорейтед Способы лечения вирусной инфекции гепатита с
US8397592B2 (en) 2010-02-19 2013-03-19 Vertex Pharmaceuticals, Inc. Systems and methods for inline sampling
US20120014912A1 (en) * 2010-07-14 2012-01-19 Vertex Pharmaceuticals Incorporated Palatable pharmaceutical composition
CA2815416A1 (en) 2010-10-21 2012-04-26 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
US9382672B2 (en) 2010-12-06 2016-07-05 Astec, Inc. Apparatus and method for dryer performance optimization system
US8863404B1 (en) * 2010-12-06 2014-10-21 Astec, Inc. Apparatus and method for dryer performance optimization system
US20130195797A1 (en) * 2012-01-31 2013-08-01 Vertex Pharmaceuticals Incorporated High potency formulations of vx-950
EP2819670A1 (en) 2012-02-27 2015-01-07 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administration thereof
TW201402153A (zh) * 2012-04-04 2014-01-16 Lonza Ag 菸鹼醯胺粉末和其製備方法及裝置
WO2014015217A1 (en) 2012-07-19 2014-01-23 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
CN102788488A (zh) * 2012-08-03 2012-11-21 梁首强 一种高速离心干燥方法及实施该方法的干燥系统
US9789063B2 (en) * 2012-09-27 2017-10-17 Basf Se Storage-stable dust-free homogeneous particulate formulation
US9744240B2 (en) * 2012-09-27 2017-08-29 Basf Se Storage-stable dust-free homogeneous particulate formulation comprising at least one water-soluble vitamin E-derivative and at least one hydrophilic polymer
CN102937290B (zh) * 2012-11-21 2015-08-26 中国东方电气集团有限公司 一种外置床式双流化床防止锅炉沾污的系统
CN104681425B (zh) * 2013-11-29 2018-07-31 细美事有限公司 基板处理装置及基板处理方法
MA39725B1 (fr) * 2014-03-14 2021-09-30 Les Laboratoires Servier Sas Compositions pharmaceutiques de composés thérapeutiquement actifs
PT107568B (pt) 2014-03-31 2018-11-05 Hovione Farm S A Processo de secagem por atomização para a produção de pós com propriedades melhoradas.
US20160016181A1 (en) * 2014-05-02 2016-01-21 Kenneth D Lathrop Bean roaster with controllable fluid loft and electrostatic collector
US9561184B2 (en) 2014-09-19 2017-02-07 Velico Medical, Inc. Methods and systems for multi-stage drying of plasma
WO2016083617A1 (en) * 2014-11-28 2016-06-02 Chr. Hansen A/S Spray freezing
EP3257574A1 (en) * 2016-06-15 2017-12-20 Clariant International Ltd Method for producing a particle-shaped material
CN109126495B (zh) * 2018-07-09 2021-06-01 山东微研生物科技有限公司 一种节能环保型维生素b2干燥装置
US11794161B1 (en) 2018-11-21 2023-10-24 Trucapsol, Llc Reduced permeability microcapsules
US11571674B1 (en) 2019-03-28 2023-02-07 Trucapsol Llc Environmentally biodegradable microcapsules
US11542392B1 (en) 2019-04-18 2023-01-03 Trucapsol Llc Multifunctional particle additive for enhancement of toughness and degradation in biodegradable polymers
WO2021104619A1 (de) 2019-11-27 2021-06-03 Symrise Ag Partikuläre erzeugnisse und verfahren zu deren herstellung
US11547978B2 (en) 2020-01-30 2023-01-10 Trucapsol Llc Environmentally biodegradable microcapsules
US12302933B2 (en) 2021-06-25 2025-05-20 Trucapsol Llc Flavor delivery system
US12187829B2 (en) 2021-08-12 2025-01-07 Trucapsol Llc Environmentally biodegradable microcapsules
US11878280B2 (en) 2022-04-19 2024-01-23 Trucapsol Llc Microcapsules comprising natural materials
US12246266B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Disposable for a spray drying system
US11998861B2 (en) 2022-09-15 2024-06-04 Velico Medical, Inc. Usability of a disposable for a spray drying plasma system
US12083447B2 (en) 2022-09-15 2024-09-10 Velico Medical, Inc. Alignment of a disposable for a spray drying plasma system
US12246093B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Methods for making spray dried plasma
WO2024059770A1 (en) 2022-09-15 2024-03-21 Velico Medical, Inc. Rapid spray drying system
US11975274B2 (en) 2022-09-15 2024-05-07 Velico Medical, Inc. Blood plasma product
US12571587B2 (en) * 2022-09-15 2026-03-10 Velico Medical, Inc. Finishing apparatus for a spray drying system
US11841189B1 (en) 2022-09-15 2023-12-12 Velico Medical, Inc. Disposable for a spray drying system
US12539355B2 (en) * 2022-09-15 2026-02-03 Velico Medical, Inc. Dryer for a spray drying system
US11904288B1 (en) 2023-02-13 2024-02-20 Trucapsol Llc Environmentally biodegradable microcapsules
US11969491B1 (en) 2023-02-22 2024-04-30 Trucapsol Llc pH triggered release particle

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK157053B (da) * 1982-06-14 1989-11-06 Niro Atomizer As Fremgangsmaade til fremstilling af et agglomereret, pulverformet maelkeprodukt
DE69325595T2 (de) * 1993-11-17 2000-03-16 Niro Holding A/S Verfahren und sprühtrocknungsgerät zum erzeugen von agglomeriertem pulver
NL1000611C2 (nl) * 1995-06-20 1996-12-23 Stork Friesland Bv Inrichting, alsmede werkwijze voor het bereiden van een gesproeidroogd produkt.
ES2287971T3 (es) * 1997-08-11 2007-12-16 Pfizer Products Inc. Dispersiones farmaceuticas solidas con biodisponibilidad incrementada.
ATE400251T1 (de) * 1999-02-09 2008-07-15 Pfizer Prod Inc Zusammensetzungen basischer arzneistoffe mit verbesserter bioverfügbarkeit
US6223455B1 (en) * 1999-05-03 2001-05-01 Acusphere, Inc. Spray drying apparatus and methods of use
JP2000334332A (ja) * 1999-05-27 2000-12-05 Kyocera Corp 噴霧乾燥装置
US20010053791A1 (en) * 2000-03-16 2001-12-20 Babcock Walter C. Glycogen phosphorylase inhibitor
AR049297A1 (es) * 2004-06-08 2006-07-12 Vertex Pharma Una composicion farmaceutica y dispersiones solidas de vx-950 (inhibidor de la proteasa de hcv ns3/4a) y proceso de obtencion
WO2007109605A2 (en) * 2006-03-20 2007-09-27 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions

Also Published As

Publication number Publication date
AU2007336516A1 (en) 2008-07-03
MX2009006806A (es) 2009-08-27
AU2007336516B2 (en) 2013-08-01
EP2101803A4 (en) 2014-05-21
WO2008080167A2 (en) 2008-07-03
NZ577820A (en) 2012-01-12
US20100011610A1 (en) 2010-01-21
EP2101803A2 (en) 2009-09-23
WO2008080167A3 (en) 2009-04-09
JP2010514703A (ja) 2010-05-06

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20121220

FZDE Discontinued

Effective date: 20150825