JP2010513539A5 - - Google Patents
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- JP2010513539A5 JP2010513539A5 JP2009542980A JP2009542980A JP2010513539A5 JP 2010513539 A5 JP2010513539 A5 JP 2010513539A5 JP 2009542980 A JP2009542980 A JP 2009542980A JP 2009542980 A JP2009542980 A JP 2009542980A JP 2010513539 A5 JP2010513539 A5 JP 2010513539A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- heavy chain
- light chain
- amino acid
- chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87106906P | 2006-12-20 | 2006-12-20 | |
| PCT/US2007/078568 WO2008079466A1 (en) | 2006-12-20 | 2007-09-14 | Antibodies and methods for making and using them |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013169145A Division JP2014028812A (ja) | 2006-12-20 | 2013-08-16 | 抗体とその製造法および使用法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010513539A JP2010513539A (ja) | 2010-04-30 |
| JP2010513539A5 true JP2010513539A5 (https=) | 2010-09-30 |
Family
ID=39536929
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009542980A Pending JP2010513539A (ja) | 2006-12-20 | 2007-09-14 | 抗体とその製造法および使用法 |
| JP2013169145A Pending JP2014028812A (ja) | 2006-12-20 | 2013-08-16 | 抗体とその製造法および使用法 |
| JP2015056137A Pending JP2015145394A (ja) | 2006-12-20 | 2015-03-19 | 抗体とその製造法および使用法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013169145A Pending JP2014028812A (ja) | 2006-12-20 | 2013-08-16 | 抗体とその製造法および使用法 |
| JP2015056137A Pending JP2015145394A (ja) | 2006-12-20 | 2015-03-19 | 抗体とその製造法および使用法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US8465741B2 (https=) |
| EP (3) | EP2716657A3 (https=) |
| JP (3) | JP2010513539A (https=) |
| KR (2) | KR101546441B1 (https=) |
| CN (2) | CN101675074B (https=) |
| AU (1) | AU2007338607B2 (https=) |
| BR (1) | BRPI0720565A2 (https=) |
| CA (2) | CA2832111A1 (https=) |
| MX (1) | MX2009006659A (https=) |
| WO (2) | WO2008079466A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0720565A2 (pt) * | 2006-12-20 | 2013-09-17 | Mmr Information Systems Inc | anticorpos e mÉtodos para a sua preparaÇço e seu uso |
| EP3181583A1 (en) | 2009-02-24 | 2017-06-21 | ESBATech, an Alcon Biomedical Research Unit LLC | Methods for identifying immunobinders of antigens |
| CN103037900B (zh) | 2010-02-24 | 2016-04-06 | 伊缪诺金公司 | 叶酸受体1抗体与免疫缀合物以及其用途 |
| JP2013529076A (ja) | 2010-05-11 | 2013-07-18 | アベオ ファーマシューティカルズ， インコーポレイテッド | 抗ｆｇｆｒ２抗体 |
| CN103620405B (zh) * | 2010-12-31 | 2016-05-25 | 生物蛋白有限公司 | 全面单克隆抗体产生 |
| US9683054B2 (en) * | 2010-12-31 | 2017-06-20 | BioAlta, LLC | Express humanization of antibodies |
| EP2673635A4 (en) * | 2011-02-07 | 2015-08-12 | Neotope Biosciences Ltd | IMMUNOTHERAPY THROUGH APOE |
| IL281714B2 (en) | 2011-04-01 | 2023-11-01 | Immunogen Inc | Methods for increasing the effectiveness of FOLR1 cancer therapy |
| CA2853637C (en) | 2011-10-26 | 2023-04-04 | Novartis Ag | Anti-canine cd20 monoclonal antibodies and methods of use |
| US12384848B2 (en) | 2011-12-19 | 2025-08-12 | The Rockefeller University | Anti-inflammatory polypeptides |
| EP2793943B1 (en) | 2011-12-19 | 2018-09-26 | The Rockefeller University | Non-sialylated anti-inflammatory polypeptides |
| HUE049693T2 (hu) | 2012-08-31 | 2020-10-28 | Immunogen Inc | Diagnosztikai ASSAY-k és készletek a folát receptor 1 kimutatására |
| CN109776676A (zh) | 2012-11-28 | 2019-05-21 | Cnj控股公司 | 针对艰难梭菌的抗体 |
| AU2014312086B2 (en) | 2013-08-30 | 2020-03-12 | Immunogen, Inc. | Antibodies and assays for detection of folate receptor 1 |
| AU2016226115B2 (en) | 2015-03-04 | 2021-03-25 | The Rockefeller University | Anti-inflammatory polypeptides |
| AU2016323968B2 (en) | 2015-09-17 | 2023-07-06 | Immunogen, Inc. | Therapeutic combinations comprising anti-FOLR1 immunoconjugates |
| CN109689684B (zh) * | 2016-07-06 | 2022-09-23 | 细胞基因公司 | 具有低免疫原性的抗体及其用途 |
| KR102733407B1 (ko) * | 2017-08-03 | 2024-11-21 | 알렉터 엘엘씨 | 항-cd33 항체 및 이의 이용 방법 |
| CA3109726A1 (en) * | 2018-08-31 | 2020-03-05 | Immune Biosolutions Inc | Antibodies specific for ntsr1 and uses thereof |
| CN111662382A (zh) * | 2019-03-06 | 2020-09-15 | 瑞阳(苏州)生物科技有限公司 | 特异结合cd3的抗体、抗原结合片段和单链抗体可变区片段及其应用 |
| JP7370569B2 (ja) * | 2019-08-07 | 2023-10-30 | 国立大学法人 大分大学 | アミロイドβタンパク質オリゴマーと結合するヒト化抗体 |
| CN115803340A (zh) * | 2020-04-24 | 2023-03-14 | 纪念斯隆凯特琳癌症中心 | 抗cd3抗体及其用途 |
| CN116635948A (zh) * | 2020-12-07 | 2023-08-22 | Absci公司 | 用于产生疾病相关蛋白质组合物的系统和方法 |
| WO2025024323A1 (en) * | 2023-07-21 | 2025-01-30 | Bighat Biosciences, Inc. | P- and e-selectin-binding compositions and methods of use thereof |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1400536A1 (en) * | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| DE69230545T2 (de) * | 1991-08-21 | 2000-07-06 | Novartis Ag, Basel | Antikörperderivate |
| ES2136092T3 (es) | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
| US5840299A (en) | 1994-01-25 | 1998-11-24 | Athena Neurosciences, Inc. | Humanized antibodies against leukocyte adhesion molecule VLA-4 |
| US5721121A (en) | 1995-06-06 | 1998-02-24 | Genentech, Inc. | Mammalian cell culture process for producing a tumor necrosis factor receptor immunoglobulin chimeric protein |
| US6764835B2 (en) | 1995-12-07 | 2004-07-20 | Diversa Corporation | Saturation mutageneis in directed evolution |
| US6171820B1 (en) | 1995-12-07 | 2001-01-09 | Diversa Corporation | Saturation mutagenesis in directed evolution |
| US6537776B1 (en) | 1999-06-14 | 2003-03-25 | Diversa Corporation | Synthetic ligation reassembly in directed evolution |
| US6562594B1 (en) | 1999-09-29 | 2003-05-13 | Diversa Corporation | Saturation mutagenesis in directed evolution |
| US5834597A (en) * | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| JP2000169393A (ja) * | 1998-09-30 | 2000-06-20 | Sankyo Co Ltd | 抗Ｆａｓ抗体を含有する医薬 |
| EP3029062A1 (en) | 2000-05-26 | 2016-06-08 | Bristol-Myers Squibb Company | Soluble ctla4 mutant molecules and uses thereof |
| US20030026806A1 (en) * | 2000-10-27 | 2003-02-06 | Amgen Inc. | Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof |
| US7321026B2 (en) * | 2001-06-27 | 2008-01-22 | Skytech Technology Limited | Framework-patched immunoglobulins |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| KR101033196B1 (ko) * | 2002-02-14 | 2011-05-09 | 이뮤노메딕스, 인코오포레이티드 | 항-ｃｄ20 항체 및 그 융합 단백질 및 이들의 이용방법 |
| AR044388A1 (es) * | 2003-05-20 | 2005-09-07 | Applied Molecular Evolution | Moleculas de union a cd20 |
| SI1629011T1 (sl) * | 2003-05-31 | 2010-05-31 | Micromet Ag | Humane molekule za vezavo anti hu cd |
| US20060228350A1 (en) | 2003-08-18 | 2006-10-12 | Medimmune, Inc. | Framework-shuffling of antibodies |
| DE602004030811D1 (de) * | 2003-10-16 | 2011-02-10 | Micromet Ag | Multispezifische deimmunisierte cd3-bindende moleküle |
| ES2672640T3 (es) | 2003-11-05 | 2018-06-15 | Roche Glycart Ag | Moléculas de unión a antígeno con afinidad de unión a receptores Fc y función efectora incrementadas |
| BRPI0508762A (pt) * | 2004-04-16 | 2007-08-14 | Genentech Inc | método de aumento do esgotamento de células b em mamìferos, método de aumento da eficácia do esgotamento de células b, método de tratamento de malignidade ou neoplasma de células b, método de alìvio de disfunção autoimunológica regulada por células b, método de esgotamento das células b e composição |
| JP2007536246A (ja) | 2004-05-05 | 2007-12-13 | ジェネンテック・インコーポレーテッド | 自己免疫疾患の予防法 |
| PL1776384T3 (pl) * | 2004-08-04 | 2013-10-31 | Mentrik Biotech Llc | WARIANTY REGIONÓW Fc |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| JP5153613B2 (ja) * | 2005-03-18 | 2013-02-27 | メディミューン，エルエルシー | 抗体のフレームワーク・シャッフル |
| KR20080031001A (ko) * | 2005-06-02 | 2008-04-07 | 아스트라제네카 아베 | Ｃｄ20에 대한 항체 및 그의 용도 |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| US10155816B2 (en) | 2005-11-28 | 2018-12-18 | Genmab A/S | Recombinant monovalent antibodies and methods for production thereof |
| BRPI0720565A2 (pt) | 2006-12-20 | 2013-09-17 | Mmr Information Systems Inc | anticorpos e mÉtodos para a sua preparaÇço e seu uso |
-
2007
- 2007-09-14 BR BRPI0720565-1A2A patent/BRPI0720565A2/pt not_active IP Right Cessation
- 2007-09-14 CA CA2832111A patent/CA2832111A1/en not_active Abandoned
- 2007-09-14 KR KR1020137022383A patent/KR101546441B1/ko not_active Expired - Fee Related
- 2007-09-14 WO PCT/US2007/078568 patent/WO2008079466A1/en not_active Ceased
- 2007-09-14 WO PCT/US2007/078566 patent/WO2008076487A2/en not_active Ceased
- 2007-09-14 CN CN200780051557.6A patent/CN101675074B/zh not_active Expired - Fee Related
- 2007-09-14 US US11/855,943 patent/US8465741B2/en not_active Expired - Fee Related
- 2007-09-14 EP EP13198591.3A patent/EP2716657A3/en not_active Withdrawn
- 2007-09-14 JP JP2009542980A patent/JP2010513539A/ja active Pending
- 2007-09-14 CN CN201310355119.6A patent/CN103709249B/zh not_active Expired - Fee Related
- 2007-09-14 MX MX2009006659A patent/MX2009006659A/es active IP Right Grant
- 2007-09-14 CA CA2673725A patent/CA2673725C/en not_active Expired - Fee Related
- 2007-09-14 EP EP13198631.7A patent/EP2716658A3/en not_active Withdrawn
- 2007-09-14 EP EP07842553A patent/EP2121756A4/en not_active Withdrawn
- 2007-09-14 AU AU2007338607A patent/AU2007338607B2/en not_active Ceased
- 2007-09-14 KR KR1020097015196A patent/KR101378302B1/ko not_active Expired - Fee Related
-
2009
- 2009-06-18 US US12/487,422 patent/US8945550B2/en not_active Expired - Fee Related
-
2013
- 2013-04-19 US US13/866,120 patent/US20130287766A1/en not_active Abandoned
- 2013-08-16 JP JP2013169145A patent/JP2014028812A/ja active Pending
-
2015
- 2015-03-19 JP JP2015056137A patent/JP2015145394A/ja active Pending