JP2024532485A5 - - Google Patents

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Publication number
JP2024532485A5
JP2024532485A5 JP2024513933A JP2024513933A JP2024532485A5 JP 2024532485 A5 JP2024532485 A5 JP 2024532485A5 JP 2024513933 A JP2024513933 A JP 2024513933A JP 2024513933 A JP2024513933 A JP 2024513933A JP 2024532485 A5 JP2024532485 A5 JP 2024532485A5
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JP
Japan
Prior art keywords
seq
variable region
chain variable
region sequence
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024513933A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024532485A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/075846 external-priority patent/WO2023034922A2/en
Publication of JP2024532485A publication Critical patent/JP2024532485A/ja
Publication of JP2024532485A5 publication Critical patent/JP2024532485A5/ja
Pending legal-status Critical Current

Links

JP2024513933A 2021-09-03 2022-09-01 Cd137および腫瘍関連抗原に結合する二重特異性結合タンパク質 Pending JP2024532485A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163240402P 2021-09-03 2021-09-03
US63/240,402 2021-09-03
US202263327700P 2022-04-05 2022-04-05
US63/327,700 2022-04-05
PCT/US2022/075846 WO2023034922A2 (en) 2021-09-03 2022-09-01 Bispecific binding proteins that bind cd137 and a tumor associated antigen

Publications (2)

Publication Number Publication Date
JP2024532485A JP2024532485A (ja) 2024-09-05
JP2024532485A5 true JP2024532485A5 (https=) 2025-09-05

Family

ID=85413134

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024513933A Pending JP2024532485A (ja) 2021-09-03 2022-09-01 Cd137および腫瘍関連抗原に結合する二重特異性結合タンパク質

Country Status (7)

Country Link
US (1) US20240383978A1 (https=)
EP (1) EP4395823A4 (https=)
JP (1) JP2024532485A (https=)
KR (1) KR20240073008A (https=)
AU (1) AU2022337286A1 (https=)
CA (1) CA3230426A1 (https=)
WO (1) WO2023034922A2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240133746A (ko) * 2022-01-09 2024-09-04 아이-맵 바이오파마 컴파니 리미티드 다중특이적 작제물 및 이의 용도
US20250049810A1 (en) 2023-08-07 2025-02-13 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
AU2024360465A1 (en) 2023-10-12 2026-04-09 Revolution Medicines, Inc. Macrocyclic ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
TW202547461A (zh) 2024-05-17 2025-12-16 美商銳新醫藥公司 Ras抑制劑
WO2025255438A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors
WO2026015790A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015801A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015796A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015825A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Use of ras inhibitor for treating pancreatic cancer
WO2026050446A1 (en) 2024-08-29 2026-03-05 Revolution Medicines, Inc. Ras inhibitors
WO2026072904A2 (en) 2024-09-26 2026-04-02 Revolution Medicines, Inc. Compositions and methods for treating lung cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2564432A1 (en) * 2004-04-27 2005-11-10 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Human anti-amyloid .beta. peptide antibody and fragment of said antibody
EP2303924B1 (en) * 2008-06-16 2016-07-27 Patrys Limited Lm-antibodies, functional fragments, lm-1 target antigen, and methods for making and using same
PT3514172T (pt) * 2014-04-01 2020-04-21 Tron Translationale Onkologie An Der Univ Der Johannes Gutenberg Univ Mainz Gemeinnuetzige Gmbh Imunorrecetores específicos de claudina-6 e epítopos de células t
EP3554544A4 (en) * 2016-12-16 2020-07-29 Bluefin Biomedicine, Inc. ANTI-PROTEIN 1 ANTIBODY CONTAINING AN ANTI-CUB DOMAIN (CDCP1), ANTIBODY-DRUG CONJUGATES AND THEIR METHODS OF USE
US10752691B2 (en) * 2018-03-13 2020-08-25 Tusk Therapeutics Ltd. Anti-CD25 antibody agents
US20220177583A1 (en) * 2019-03-20 2022-06-09 The Regents Of The University Of California Claudin-6 bispecific antibodies
BR112021008870A2 (pt) * 2019-08-12 2021-11-30 Abl Bio Inc Anticorpo, um ou mais polinucleotídeos, composição, uso do anticorpo, e, método para tratar câncer.
AU2020337958A1 (en) * 2019-08-28 2022-03-17 Horizon Therapeutics Ireland Dac Methods for the treatment of thyroid eye disease
JP7758672B2 (ja) * 2019-12-20 2025-10-22 ノヴァロック バイオセラピューティクス, リミテッド 抗インターロイキン-23 p19抗体およびそれの使用方法
CA3174094A1 (en) * 2020-03-31 2021-10-07 Shinya Ishii Claudin-6 targeting multispecific antigen-binding molecules and uses thereof
US20250277026A1 (en) * 2021-03-02 2025-09-04 Novarock Biotherapeutics, Ltd. Antibodies against claudin-6 and uses thereof

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