JP2025505611A5 - - Google Patents
Info
- Publication number
- JP2025505611A5 JP2025505611A5 JP2024546159A JP2024546159A JP2025505611A5 JP 2025505611 A5 JP2025505611 A5 JP 2025505611A5 JP 2024546159 A JP2024546159 A JP 2024546159A JP 2024546159 A JP2024546159 A JP 2024546159A JP 2025505611 A5 JP2025505611 A5 JP 2025505611A5
- Authority
- JP
- Japan
- Prior art keywords
- psma
- seq
- amino acid
- acid sequence
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210116684 | 2022-02-07 | ||
| CN202210116684.6 | 2022-02-07 | ||
| PCT/CN2023/074735 WO2023147784A1 (zh) | 2022-02-07 | 2023-02-07 | 特异性结合psma和cd3的抗原结合分子及其医药用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025505611A JP2025505611A (ja) | 2025-02-28 |
| JP2025505611A5 true JP2025505611A5 (https=) | 2026-02-17 |
Family
ID=87553110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024546159A Pending JP2025505611A (ja) | 2022-02-07 | 2023-02-07 | Ｐｓｍａとｃｄ３に特異的に結合する抗原結合分子及びその医薬的使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250043022A1 (https=) |
| EP (1) | EP4477669A4 (https=) |
| JP (1) | JP2025505611A (https=) |
| KR (1) | KR20240139065A (https=) |
| CN (1) | CN118574855A (https=) |
| TW (1) | TW202337902A (https=) |
| WO (1) | WO2023147784A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2024319528A1 (en) * | 2023-08-04 | 2026-02-12 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Anti-psma antibody-drug conjugate and pharmaceutical use thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5959177A (en) | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| ATE299938T1 (de) | 1997-05-02 | 2005-08-15 | Genentech Inc | Ein verfahren zur herstellung multispezifischer antikörper die heteromultimere und gemeinsame komponenten besitzen |
| US6040498A (en) | 1998-08-11 | 2000-03-21 | North Caroline State University | Genetically engineered duckweed |
| ES2248127T3 (es) | 1999-10-04 | 2006-03-16 | Medicago Inc. | Metodo para regular la transcripcion de genes foraneos en presencia de nigtrogeno. |
| US7125978B1 (en) | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| US7514078B2 (en) * | 2001-06-01 | 2009-04-07 | Cornell Research Foundation, Inc. | Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies |
| AU2006232287B2 (en) | 2005-03-31 | 2011-10-06 | Chugai Seiyaku Kabushiki Kaisha | Methods for producing polypeptides by regulating polypeptide association |
| PT1999154E (pt) | 2006-03-24 | 2013-01-24 | Merck Patent Gmbh | Domínios proteicos heterodiméricos modificados |
| JP2009541275A (ja) | 2006-06-22 | 2009-11-26 | ノボ・ノルデイスク・エー／エス | 二重特異性抗体の生産 |
| JP6157046B2 (ja) | 2008-01-07 | 2017-07-05 | アムジェン インコーポレイテッド | 静電的ステアリング（ｅｌｅｃｔｒｏｓｔａｔｉｃｓｔｅｅｒｉｎｇ）効果を用いた抗体Ｆｃヘテロ二量体分子を作製するための方法 |
| WO2010129304A2 (en) | 2009-04-27 | 2010-11-11 | Oncomed Pharmaceuticals, Inc. | Method for making heteromultimeric molecules |
| CA2785907A1 (en) | 2009-12-29 | 2011-07-28 | Emergent Product Development Seattle, Llc | Ron binding constructs and methods of use thereof |
| US9527926B2 (en) | 2010-05-14 | 2016-12-27 | Rinat Neuroscience Corp. | Heterodimeric proteins and methods for producing and purifying them |
| ES2758994T3 (es) | 2010-11-05 | 2020-05-07 | Zymeworks Inc | Diseño anticuerpo heterodimérico estable con mutaciones en el dominio Fc |
| RS60499B1 (sr) | 2011-12-20 | 2020-08-31 | Medimmune Llc | Modifikovani polipeptidi za bispecifične skelete antitela |
| US9248181B2 (en) | 2012-04-20 | 2016-02-02 | Merus B.V. | Methods and means for the production of Ig-like molecules |
| EP3291836A4 (en) * | 2015-05-06 | 2018-11-14 | Janssen Biotech, Inc. | Prostate specific membrane antigen (psma) bispecific binding agents and uses thereof |
| EA201891753A1 (ru) | 2016-02-03 | 2019-01-31 | Эмджен Рисерч (Мюник) Гмбх | Биспецифические конструкции антител к psma и cd3, вовлекающие т-клетки |
| BR112018074453A2 (pt) * | 2016-05-27 | 2019-03-19 | Abbvie Biotherapeutics Inc. | proteínas de ligação biespecíficas ligando uma protéina imunomoduladora e um antígeno tumoral |
| WO2018129284A1 (en) * | 2017-01-05 | 2018-07-12 | The Johns Hopkins University | Development of new monoclonal antibodies recognizing human prostate-specific membrane antigen (psma) |
| JP7599205B2 (ja) * | 2018-06-01 | 2024-12-13 | アンヘレス セラピューティクス インコーポレイテッド | 細胞療法のための多様な抗原結合ドメイン、新規プラットフォームおよびその他の強化 |
| CN116239698A (zh) | 2019-03-06 | 2023-06-09 | 江苏恒瑞医药股份有限公司 | 双功能融合蛋白及其医药用途 |
| CN118526580A (zh) * | 2019-06-21 | 2024-08-23 | 瑞泽恩制药公司 | 结合psma和cd3的双特异性抗原结合分子与4-1bb共刺激组合的用途 |
| WO2021139758A1 (zh) | 2020-01-09 | 2021-07-15 | 江苏恒瑞医药股份有限公司 | 新型多肽复合物 |
-
2023
- 2023-02-07 KR KR1020247027763A patent/KR20240139065A/ko active Pending
- 2023-02-07 WO PCT/CN2023/074735 patent/WO2023147784A1/zh not_active Ceased
- 2023-02-07 CN CN202380017887.2A patent/CN118574855A/zh active Pending
- 2023-02-07 JP JP2024546159A patent/JP2025505611A/ja active Pending
- 2023-02-07 EP EP23749363.0A patent/EP4477669A4/en active Pending
- 2023-02-07 US US18/835,963 patent/US20250043022A1/en active Pending
- 2023-02-07 TW TW112104291A patent/TW202337902A/zh unknown
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