JP2025160226A5 - - Google Patents

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Publication number
JP2025160226A5
JP2025160226A5 JP2025114854A JP2025114854A JP2025160226A5 JP 2025160226 A5 JP2025160226 A5 JP 2025160226A5 JP 2025114854 A JP2025114854 A JP 2025114854A JP 2025114854 A JP2025114854 A JP 2025114854A JP 2025160226 A5 JP2025160226 A5 JP 2025160226A5
Authority
JP
Japan
Prior art keywords
domain
heterodimeric protein
polypeptide
residue
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025114854A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025160226A (ja
Filing date
Publication date
Priority claimed from JP2022544309A external-priority patent/JP7710450B2/ja
Application filed filed Critical
Publication of JP2025160226A publication Critical patent/JP2025160226A/ja
Publication of JP2025160226A5 publication Critical patent/JP2025160226A5/ja
Pending legal-status Critical Current

Links

JP2025114854A 2020-01-23 2025-07-08 Fc変異を有するヘテロダイマータンパク質 Pending JP2025160226A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CNPCT/CN2020/073960 2020-01-23
CN2020073960 2020-01-23
JP2022544309A JP7710450B2 (ja) 2020-01-23 2021-01-22 Fc変異を有するヘテロダイマータンパク質
PCT/CN2021/073347 WO2021148006A1 (en) 2020-01-23 2021-01-22 Heterodimeric proteins with fc mutations

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022544309A Division JP7710450B2 (ja) 2020-01-23 2021-01-22 Fc変異を有するヘテロダイマータンパク質

Publications (2)

Publication Number Publication Date
JP2025160226A JP2025160226A (ja) 2025-10-22
JP2025160226A5 true JP2025160226A5 (https=) 2026-03-11

Family

ID=76992067

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022544309A Active JP7710450B2 (ja) 2020-01-23 2021-01-22 Fc変異を有するヘテロダイマータンパク質
JP2025114854A Pending JP2025160226A (ja) 2020-01-23 2025-07-08 Fc変異を有するヘテロダイマータンパク質

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2022544309A Active JP7710450B2 (ja) 2020-01-23 2021-01-22 Fc変異を有するヘテロダイマータンパク質

Country Status (11)

Country Link
US (1) US20230124669A1 (https=)
EP (1) EP4093778A4 (https=)
JP (2) JP7710450B2 (https=)
KR (1) KR20220145833A (https=)
CN (1) CN115279796A (https=)
AU (1) AU2021210482A1 (https=)
BR (1) BR112022014574A2 (https=)
CA (1) CA3165045A1 (https=)
IL (1) IL294878A (https=)
MX (1) MX2022009101A (https=)
WO (1) WO2021148006A1 (https=)

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WO2022170619A1 (en) * 2021-02-11 2022-08-18 Adagene Pte. Ltd. Anti-cd3 antibodies and methods of use thereof
US12441816B2 (en) 2021-09-21 2025-10-14 Qilu Puget Sound Biotherapeutics Corporation Heterodimeric Fc for making fusion proteins and bispecific antibodies
US20250333539A1 (en) * 2022-03-23 2025-10-30 Cytomx Therapeutics, Inc. Activatable antigen-binding protein constructs and uses of the same
WO2023193239A1 (en) 2022-04-08 2023-10-12 Peter Peizhi Luo Anti-cd28 antibodies and methods of use thereof
CN121666401A (zh) * 2023-07-10 2026-03-13 瑞泽恩制药公司 双特异性PD-L1x4-1BB抗体及其使用方法
TW202528360A (zh) * 2023-11-20 2025-07-16 大陸商江蘇恆瑞醫藥股份有限公司 藉由重組反應製備異源多聚體的方法

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US8054928B2 (en) * 2005-11-14 2011-11-08 Ati Technologies, Inc. Programmable preamble system and method
RU2636046C2 (ru) * 2009-01-12 2017-11-17 Сайтомкс Терапьютикс, Инк Композиции модифицированных антител, способы их получения и применения
WO2011028952A1 (en) * 2009-09-02 2011-03-10 Xencor, Inc. Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
CA2785907A1 (en) * 2009-12-29 2011-07-28 Emergent Product Development Seattle, Llc Ron binding constructs and methods of use thereof
EP2576621B1 (en) * 2010-05-27 2019-04-10 Genmab A/S Monoclonal antibodies against her2
SG11201401422VA (en) * 2011-10-27 2014-09-26 Genmab As Production of heterodimeric proteins
WO2013118722A1 (ja) * 2012-02-06 2013-08-15 トヨタ自動車株式会社 硫化物固体電解質材料、電池および硫化物固体電解質材料の製造方法
UY35148A (es) * 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
JP6594855B2 (ja) * 2013-03-15 2019-10-23 ゼンコア インコーポレイテッド ヘテロ二量体タンパク質
JP2016538275A (ja) * 2013-11-04 2016-12-08 グレンマーク ファーマシューティカルズ, エセ.アー. T細胞再標的化ヘテロ二量体免疫グロブリン(hetero−dimeric immunoglobulin)の製造
US20160176969A1 (en) * 2014-11-26 2016-06-23 Xencor, Inc. Heterodimeric antibodies including binding to cd8
EP3227332B1 (en) * 2014-12-03 2019-11-06 F.Hoffmann-La Roche Ag Multispecific antibodies
CN107408987B (zh) * 2015-03-20 2020-03-17 日本电气株式会社 可插拔光模块、光通信系统和可插拔光模块控制方法
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WO2019148445A1 (en) * 2018-02-02 2019-08-08 Adagene Inc. Precision/context-dependent activatable antibodies, and methods of making and using the same
TWI798601B (zh) * 2020-11-27 2023-04-11 晶睿通訊股份有限公司 地面起伏偵測方法及其監控攝影機
JP7295438B2 (ja) * 2020-11-30 2023-06-21 日亜化学工業株式会社 面状光源
WO2023193239A1 (en) * 2022-04-08 2023-10-12 Peter Peizhi Luo Anti-cd28 antibodies and methods of use thereof

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