JP2025160226A5 - - Google Patents
Info
- Publication number
- JP2025160226A5 JP2025160226A5 JP2025114854A JP2025114854A JP2025160226A5 JP 2025160226 A5 JP2025160226 A5 JP 2025160226A5 JP 2025114854 A JP2025114854 A JP 2025114854A JP 2025114854 A JP2025114854 A JP 2025114854A JP 2025160226 A5 JP2025160226 A5 JP 2025160226A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- heterodimeric protein
- polypeptide
- residue
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2020/073960 | 2020-01-23 | ||
| CN2020073960 | 2020-01-23 | ||
| JP2022544309A JP7710450B2 (ja) | 2020-01-23 | 2021-01-22 | Ｆｃ変異を有するヘテロダイマータンパク質 |
| PCT/CN2021/073347 WO2021148006A1 (en) | 2020-01-23 | 2021-01-22 | Heterodimeric proteins with fc mutations |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022544309A Division JP7710450B2 (ja) | 2020-01-23 | 2021-01-22 | Ｆｃ変異を有するヘテロダイマータンパク質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025160226A JP2025160226A (ja) | 2025-10-22 |
| JP2025160226A5 true JP2025160226A5 (https=) | 2026-03-11 |
Family
ID=76992067
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022544309A Active JP7710450B2 (ja) | 2020-01-23 | 2021-01-22 | Ｆｃ変異を有するヘテロダイマータンパク質 |
| JP2025114854A Pending JP2025160226A (ja) | 2020-01-23 | 2025-07-08 | Ｆｃ変異を有するヘテロダイマータンパク質 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022544309A Active JP7710450B2 (ja) | 2020-01-23 | 2021-01-22 | Ｆｃ変異を有するヘテロダイマータンパク質 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230124669A1 (https=) |
| EP (1) | EP4093778A4 (https=) |
| JP (2) | JP7710450B2 (https=) |
| KR (1) | KR20220145833A (https=) |
| CN (1) | CN115279796A (https=) |
| AU (1) | AU2021210482A1 (https=) |
| BR (1) | BR112022014574A2 (https=) |
| CA (1) | CA3165045A1 (https=) |
| IL (1) | IL294878A (https=) |
| MX (1) | MX2022009101A (https=) |
| WO (1) | WO2021148006A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022170619A1 (en) * | 2021-02-11 | 2022-08-18 | Adagene Pte. Ltd. | Anti-cd3 antibodies and methods of use thereof |
| EP4405398A4 (en) * | 2021-09-21 | 2025-10-29 | Qilu Puget Sound Biotherapeutics Corp | FC HETERODIMERS ALLOWING THE MANUFACTURE OF FUSION PROTEINS AND BI-SPECIFIC ANTIBODIES |
| WO2023183888A1 (en) * | 2022-03-23 | 2023-09-28 | Cytomx Therapeutics, Inc. | Activatable antigen-binding protein constructs and uses of the same |
| WO2023193239A1 (en) | 2022-04-08 | 2023-10-12 | Peter Peizhi Luo | Anti-cd28 antibodies and methods of use thereof |
| AU2024287529A1 (en) * | 2023-07-10 | 2026-02-05 | Regeneron Pharmaceuticals, Inc. | Bispecific pd-l1x4-1bb antibodies and methods of use thereof |
| WO2025108310A1 (zh) * | 2023-11-20 | 2025-05-30 | 江苏恒瑞医药股份有限公司 | 通过重组反应制备异源多聚体的方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101270829B1 (ko) * | 2004-09-23 | 2013-06-07 | 제넨테크, 인크. | 시스테인 유전자조작 항체 및 접합체 |
| US8054928B2 (en) * | 2005-11-14 | 2011-11-08 | Ati Technologies, Inc. | Programmable preamble system and method |
| US20100189651A1 (en) * | 2009-01-12 | 2010-07-29 | Cytomx Therapeutics, Llc | Modified antibody compositions, methods of making and using thereof |
| US9493578B2 (en) * | 2009-09-02 | 2016-11-15 | Xencor, Inc. | Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens |
| CN102958942A (zh) * | 2009-12-29 | 2013-03-06 | 新兴产品开发西雅图有限公司 | 异二聚体结合蛋白及其应用 |
| CN114805583A (zh) * | 2010-05-27 | 2022-07-29 | 根马布股份公司 | 针对her2的单克隆抗体 |
| US10344050B2 (en) * | 2011-10-27 | 2019-07-09 | Genmab A/S | Production of heterodimeric proteins |
| WO2013118722A1 (ja) * | 2012-02-06 | 2013-08-15 | トヨタ自動車株式会社 | 硫化物固体電解質材料、電池および硫化物固体電解質材料の製造方法 |
| UY35148A (es) * | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
| CA2902739C (en) * | 2013-03-15 | 2022-11-22 | Xencor, Inc. | Heterodimeric proteins |
| CN110627907B (zh) * | 2013-11-04 | 2024-03-29 | 艾科诺斯科技股份有限公司 | 重靶向t细胞的异源二聚免疫球蛋白的产生 |
| US20160176969A1 (en) * | 2014-11-26 | 2016-06-23 | Xencor, Inc. | Heterodimeric antibodies including binding to cd8 |
| CN107001482B (zh) * | 2014-12-03 | 2021-06-15 | 豪夫迈·罗氏有限公司 | 多特异性抗体 |
| WO2016152136A1 (ja) * | 2015-03-20 | 2016-09-29 | 日本電気株式会社 | プラガブル光モジュール、光通信システム及びプラガブル光モジュールの制御方法 |
| CN106883297B (zh) * | 2015-12-16 | 2019-12-13 | 苏州康宁杰瑞生物科技有限公司 | 基于ch3结构域的异二聚体分子、其制备方法及用途 |
| EP3489262A4 (en) * | 2016-07-19 | 2020-07-08 | Ibentrus, Inc. | BISPECIFIC PROTEINS AND PROCESSES FOR THEIR PREPARATION |
| WO2019014912A1 (zh) * | 2017-07-21 | 2019-01-24 | 赵磊 | 一种异二聚体蛋白及其制备方法 |
| EP3728326A4 (en) * | 2017-12-21 | 2021-12-15 | Amunix Pharmaceuticals, Inc. | SEPARATING SEGMENTS AND BINDING COMPOSITIONS THEREFORE |
| WO2019148445A1 (en) * | 2018-02-02 | 2019-08-08 | Adagene Inc. | Precision/context-dependent activatable antibodies, and methods of making and using the same |
| TWI798601B (zh) * | 2020-11-27 | 2023-04-11 | 晶睿通訊股份有限公司 | 地面起伏偵測方法及其監控攝影機 |
| JP7295438B2 (ja) * | 2020-11-30 | 2023-06-21 | 日亜化学工業株式会社 | 面状光源 |
| WO2023193239A1 (en) * | 2022-04-08 | 2023-10-12 | Peter Peizhi Luo | Anti-cd28 antibodies and methods of use thereof |
-
2021
- 2021-01-22 WO PCT/CN2021/073347 patent/WO2021148006A1/en not_active Ceased
- 2021-01-22 CA CA3165045A patent/CA3165045A1/en active Pending
- 2021-01-22 BR BR112022014574A patent/BR112022014574A2/pt unknown
- 2021-01-22 MX MX2022009101A patent/MX2022009101A/es unknown
- 2021-01-22 KR KR1020227029071A patent/KR20220145833A/ko active Pending
- 2021-01-22 IL IL294878A patent/IL294878A/en unknown
- 2021-01-22 US US17/759,282 patent/US20230124669A1/en active Pending
- 2021-01-22 AU AU2021210482A patent/AU2021210482A1/en active Pending
- 2021-01-22 EP EP21744991.7A patent/EP4093778A4/en active Pending
- 2021-01-22 CN CN202180021100.0A patent/CN115279796A/zh active Pending
- 2021-01-22 JP JP2022544309A patent/JP7710450B2/ja active Active
-
2025
- 2025-07-08 JP JP2025114854A patent/JP2025160226A/ja active Pending