JP2022512132A5 - - Google Patents

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Publication number
JP2022512132A5
JP2022512132A5 JP2021532180A JP2021532180A JP2022512132A5 JP 2022512132 A5 JP2022512132 A5 JP 2022512132A5 JP 2021532180 A JP2021532180 A JP 2021532180A JP 2021532180 A JP2021532180 A JP 2021532180A JP 2022512132 A5 JP2022512132 A5 JP 2022512132A5
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JP
Japan
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JP2021532180A
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Japanese (ja)
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JP7458399B2 (ja
JP2022512132A (ja
JPWO2020114480A5 (https=
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Priority claimed from PCT/CN2019/123588 external-priority patent/WO2020114480A1/en
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Publication of JPWO2020114480A5 publication Critical patent/JPWO2020114480A5/ja
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JP2021532180A 2018-12-07 2019-12-06 抗クローディン抗体及びそれらの使用 Active JP7458399B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2018/119797 2018-12-07
CNPCT/CN2018/119797 2018-12-07
PCT/CN2019/123588 WO2020114480A1 (en) 2018-12-07 2019-12-06 Anti-claudin antibodies and uses thereof

Publications (4)

Publication Number Publication Date
JP2022512132A JP2022512132A (ja) 2022-02-02
JP2022512132A5 true JP2022512132A5 (https=) 2022-12-13
JPWO2020114480A5 JPWO2020114480A5 (https=) 2022-12-13
JP7458399B2 JP7458399B2 (ja) 2024-03-29

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JP2021532180A Active JP7458399B2 (ja) 2018-12-07 2019-12-06 抗クローディン抗体及びそれらの使用

Country Status (12)

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US (1) US20210380680A1 (https=)
EP (1) EP3891183A4 (https=)
JP (1) JP7458399B2 (https=)
KR (1) KR20210100655A (https=)
CN (1) CN113423735B (https=)
AU (1) AU2019391204A1 (https=)
BR (1) BR112021011014A2 (https=)
CA (1) CA3122135A1 (https=)
IL (1) IL283754A (https=)
MX (1) MX2021006681A (https=)
SG (1) SG11202105885WA (https=)
WO (1) WO2020114480A1 (https=)

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Publication number Priority date Publication date Assignee Title
US12297265B2 (en) 2018-12-28 2025-05-13 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Antibody and use thereof
CA3128502A1 (en) 2019-02-01 2020-08-06 Novarock Biotherapeutics, Ltd. Anti-claudin 18 antibodies and methods of use thereof
CN115943162A (zh) * 2020-06-19 2023-04-07 信达生物制药(苏州)有限公司 抗Claudin18.2抗体以及其用途
CN113929780A (zh) * 2020-07-13 2022-01-14 北京凯因科技股份有限公司 一种结合密蛋白的用于治疗癌症的人源化抗体
KR20230079096A (ko) * 2020-09-30 2023-06-05 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 항체-약물 접합체를 포함하는 약제학적 조성물 및 약제학적 조성물의 용도
US20240034784A1 (en) * 2020-09-30 2024-02-01 Nanjing GenScript Biotech Co., Ltd. Antibodies targeting human claudin 18.2 and uses thereof
CN115109154A (zh) * 2021-03-17 2022-09-27 三优生物医药(上海)有限公司 一种靶向cldn18.2的抗体或其抗原结合片段及其应用
CN115611983A (zh) * 2021-07-14 2023-01-17 三优生物医药(上海)有限公司 Cldn18.2结合分子及其用途
WO2023066267A1 (en) * 2021-10-19 2023-04-27 Biosion Inc. Antibodies binding cldn18.2 and uses thereof
CN114044822B (zh) * 2021-10-28 2023-06-27 杭州博茵生物技术有限公司 血清淀粉样蛋白a抗体的重链和轻链可变区、抗体及运用
CN118139888A (zh) * 2021-11-05 2024-06-04 正大天晴药业集团股份有限公司 抗cldn18.2抗体及其用途
CN114395040B (zh) * 2022-02-09 2023-12-15 东南大学附属中大医院 再生蛋白reg1a单克隆抗体及其应用
WO2023196882A1 (en) 2022-04-06 2023-10-12 Zai Lab (Us) Llc Claudin 18.2 immunohistochemistry assay and use thereof
CN117229398A (zh) * 2022-06-15 2023-12-15 中山康方生物医药有限公司 抗cldn18.2抗体、其药物组合物及用途
CA3261520A1 (en) * 2022-07-08 2024-01-11 Telix Targeting Technologies, Inc. ANTIBODIES, THEIR MANUFACTURING PROCESSES AND METHODS OF USE
WO2024131683A1 (zh) * 2022-12-19 2024-06-27 华润生物医药有限公司 结合cldn18.2的抗体和抗体药物偶联物及其用途
IL326136A (en) 2023-08-07 2026-03-01 Revolution Medicines Inc RMC-6291 for use in the treatment of a disease or disorder associated with the RAS protein
US20250154171A1 (en) 2023-10-12 2025-05-15 Revolution Medicines, Inc. Ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
US20250375445A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors
WO2026015825A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Use of ras inhibitor for treating pancreatic cancer
WO2026015796A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015790A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015801A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026050446A1 (en) 2024-08-29 2026-03-05 Revolution Medicines, Inc. Ras inhibitors
WO2026072904A2 (en) 2024-09-26 2026-04-02 Revolution Medicines, Inc. Compositions and methods for treating lung cancer

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DE102004024617A1 (de) * 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
EP1790664A1 (en) * 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoclonal antibodies against claudin-18 for treatment of cancer
EP1997832A1 (en) * 2007-05-29 2008-12-03 Ganymed Pharmaceuticals AG Monoclonal antibodies against Claudin-18 for treatment of cancer
WO2013167153A1 (en) * 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
WO2013174404A1 (en) * 2012-05-23 2013-11-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2014146672A1 (en) * 2013-03-18 2014-09-25 Ganymed Pharmaceuticals Ag Therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2016165762A1 (en) * 2015-04-15 2016-10-20 Ganymed Pharmaceuticals Ag Drug conjugates comprising antibodies against claudin 18.2
AU2017294276B2 (en) * 2016-07-08 2024-08-01 Crage Medical Co., Limited Antibody for anti-claudin 18A2 and use thereof
WO2018054484A1 (en) * 2016-09-23 2018-03-29 Biontech Ag Bispecific trivalent antibodies binding to claudin 6 or claudin18.2 and cd3 for treatment of claudin expressing cancer diseases

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