JP2010512407A - 新生物を処置するための組成物および方法 - Google Patents

新生物を処置するための組成物および方法 Download PDF

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Publication number
JP2010512407A
JP2010512407A JP2009541425A JP2009541425A JP2010512407A JP 2010512407 A JP2010512407 A JP 2010512407A JP 2009541425 A JP2009541425 A JP 2009541425A JP 2009541425 A JP2009541425 A JP 2009541425A JP 2010512407 A JP2010512407 A JP 2010512407A
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Prior art keywords
vegf
antibody
thalidomide
patient
relapsed
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JP2009541425A
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Japanese (ja)
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JP2010512407A5 (cg-RX-API-DMAC7.html
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ロバート ディー． マス
グレゴリー ディー． プラウマン
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ジェネンテック インコーポレイテッド
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Publication of JP2010512407A5 publication Critical patent/JP2010512407A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2009541425A 2006-12-11 2007-05-04 新生物を処置するための組成物および方法 Pending JP2010512407A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87446006P 2006-12-11 2006-12-11
PCT/US2007/068300 WO2008073509A2 (en) 2006-12-11 2007-05-04 Compositions and methods for treating a neoplasm

Publications (2)

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JP2010512407A true JP2010512407A (ja) 2010-04-22
JP2010512407A5 JP2010512407A5 (cg-RX-API-DMAC7.html) 2012-06-14

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JP2009541425A Pending JP2010512407A (ja) 2006-12-11 2007-05-04 新生物を処置するための組成物および方法

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US (1) US20100086544A1 (cg-RX-API-DMAC7.html)
EP (1) EP2099489B1 (cg-RX-API-DMAC7.html)
JP (1) JP2010512407A (cg-RX-API-DMAC7.html)
KR (1) KR101320198B1 (cg-RX-API-DMAC7.html)
CN (1) CN101547705B (cg-RX-API-DMAC7.html)
AU (1) AU2007333565A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0717688A2 (cg-RX-API-DMAC7.html)
CA (1) CA2670707A1 (cg-RX-API-DMAC7.html)
DK (1) DK2099489T3 (cg-RX-API-DMAC7.html)
IL (1) IL198852A (cg-RX-API-DMAC7.html)
MX (1) MX2009006202A (cg-RX-API-DMAC7.html)
NZ (1) NZ577058A (cg-RX-API-DMAC7.html)
RU (1) RU2482877C2 (cg-RX-API-DMAC7.html)
SG (1) SG177891A1 (cg-RX-API-DMAC7.html)
SI (1) SI2099489T1 (cg-RX-API-DMAC7.html)
WO (1) WO2008073509A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200903489B (cg-RX-API-DMAC7.html)

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ME02371B (me) 2006-09-29 2016-06-20 Oncomed Pharm Inc Sastojci i postupci za dijagnstikovanje i tretman raka
US8883145B2 (en) 2009-10-16 2014-11-11 Oncomed Pharmaceuticals, Inc. Methods of treatment with DLL4 antagonists and an anti-hypertensive agent
US8551479B2 (en) 2010-09-10 2013-10-08 Oncomed Pharmaceuticals, Inc. Methods for treating melanoma
WO2012088438A1 (en) * 2010-12-22 2012-06-28 Eutropics Pharmaceuticals, Inc. Compositions and methods useful for treating diseases
CN107722122B (zh) 2011-09-23 2022-05-27 昂考梅德药品有限公司 Vegf/dll4结合剂及其应用
RU2672553C2 (ru) * 2012-03-14 2018-11-16 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Соединения и способы лечения лейкемии
AU2013337811A1 (en) 2012-10-31 2015-05-14 Oncomed Pharmaceuticals, Inc. Methods and monitoring of treatment with a DLL4 antagonist
GB201409471D0 (en) * 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
PT3212233T (pt) 2014-10-31 2020-07-16 Oncomed Pharm Inc Terapia combinada para o tratamento de doenças
RU2700696C2 (ru) 2015-07-27 2019-09-19 Чонг Кун Данг Фармасьютикал Корп. 1,3,4,-оксадизоламидное производное соединение в качестве ингибитора гистондеацетилазы 6 и содержащая его фармацевтическая композиция
WO2017018803A1 (en) 2015-07-27 2017-02-02 Chong Kun Dang Pharmaceutical Corp. 1,3,4-oxadiazole sulfonamide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same
NZ736432A (en) 2015-07-27 2019-01-25 Chong Kun Dang Pharmaceutical Corp 1,3,4-oxadiazole sulfamide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same
HUE057544T2 (hu) 2015-08-04 2022-05-28 Chong Kun Dang Pharmaceutical Corp 1,3,4-oxadiazol-származék vegyületek mint hiszton deacetiláz 6 inhibitorok, és ezeket tartalmazó gyógyszerkészítmények
ES2968074T3 (es) 2015-09-23 2024-05-07 Mereo Biopharma 5 Inc Anticuerpo bi-específico anti-VEGF/DLL4 para su uso en el tratamiento del cáncer de ovario resistente al platino
RU2695133C1 (ru) 2015-10-12 2019-07-22 Чонг Кун Данг Фармасьютикал Корп. Производные оксадиазоламина в качестве ингибитора гистондеацетилазы 6 и содержащая их фармацевтическая композиция
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
ES3009668T3 (en) 2018-01-26 2025-03-31 Univ California Methods and compositions for treatment of angiogenic disorders using anti-vegf agents
KR102316234B1 (ko) 2018-07-26 2021-10-22 주식회사 종근당 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물
EP3976602A4 (en) 2019-05-31 2023-05-31 Chong Kun Dang Pharmaceutical Corp. 1,3,4-OXADIAZOLE HOMOPHTHALIMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE-6 INHIBITOR AND PHARMACEUTICAL COMPOSITION THEREOF
CA3168512A1 (en) 2019-11-25 2021-06-03 Napoleone Ferrara Long-acting vegf inhibitors for intraocular neovascularization

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WO2005012359A2 (en) * 2003-08-01 2005-02-10 Genentech, Inc. Anti-vegf antibodies

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Also Published As

Publication number Publication date
NZ577058A (en) 2012-04-27
RU2482877C2 (ru) 2013-05-27
SG177891A1 (en) 2012-02-28
IL198852A (en) 2013-06-27
EP2099489A2 (en) 2009-09-16
US20100086544A1 (en) 2010-04-08
MX2009006202A (es) 2009-06-22
WO2008073509A2 (en) 2008-06-19
DK2099489T3 (da) 2014-08-18
CA2670707A1 (en) 2008-06-19
SI2099489T1 (sl) 2014-09-30
CN101547705A (zh) 2009-09-30
ZA200903489B (en) 2010-08-25
KR101320198B1 (ko) 2013-10-30
IL198852A0 (en) 2011-08-01
CN101547705B (zh) 2013-06-12
KR20090087908A (ko) 2009-08-18
HK1131064A1 (en) 2010-01-15
BRPI0717688A2 (pt) 2013-01-22
WO2008073509A3 (en) 2009-01-08
AU2007333565A1 (en) 2008-06-19
EP2099489B1 (en) 2014-05-21
RU2009126588A (ru) 2011-01-20

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