AU2007333565A1 - Compositions and methods for treating a neoplasm - Google Patents

Compositions and methods for treating a neoplasm Download PDF

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Publication number
AU2007333565A1
AU2007333565A1 AU2007333565A AU2007333565A AU2007333565A1 AU 2007333565 A1 AU2007333565 A1 AU 2007333565A1 AU 2007333565 A AU2007333565 A AU 2007333565A AU 2007333565 A AU2007333565 A AU 2007333565A AU 2007333565 A1 AU2007333565 A1 AU 2007333565A1
Authority
AU
Australia
Prior art keywords
vegf
antibody
thalidomide
bortezomib
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007333565A
Other languages
English (en)
Inventor
Robert D. Mass
Gregory D. Plowman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of AU2007333565A1 publication Critical patent/AU2007333565A1/en
Priority to AU2014201911A priority Critical patent/AU2014201911A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2007333565A 2006-12-11 2007-05-04 Compositions and methods for treating a neoplasm Abandoned AU2007333565A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014201911A AU2014201911A1 (en) 2006-12-11 2014-04-03 Compositions and methods for treating a neoplasm

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87446006P 2006-12-11 2006-12-11
US60/874,460 2006-12-11
PCT/US2007/068300 WO2008073509A2 (en) 2006-12-11 2007-05-04 Compositions and methods for treating a neoplasm

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2014201911A Division AU2014201911A1 (en) 2006-12-11 2014-04-03 Compositions and methods for treating a neoplasm

Publications (1)

Publication Number Publication Date
AU2007333565A1 true AU2007333565A1 (en) 2008-06-19

Family

ID=38521756

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007333565A Abandoned AU2007333565A1 (en) 2006-12-11 2007-05-04 Compositions and methods for treating a neoplasm

Country Status (17)

Country Link
US (1) US20100086544A1 (cg-RX-API-DMAC7.html)
EP (1) EP2099489B1 (cg-RX-API-DMAC7.html)
JP (1) JP2010512407A (cg-RX-API-DMAC7.html)
KR (1) KR101320198B1 (cg-RX-API-DMAC7.html)
CN (1) CN101547705B (cg-RX-API-DMAC7.html)
AU (1) AU2007333565A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0717688A2 (cg-RX-API-DMAC7.html)
CA (1) CA2670707A1 (cg-RX-API-DMAC7.html)
DK (1) DK2099489T3 (cg-RX-API-DMAC7.html)
IL (1) IL198852A (cg-RX-API-DMAC7.html)
MX (1) MX2009006202A (cg-RX-API-DMAC7.html)
NZ (1) NZ577058A (cg-RX-API-DMAC7.html)
RU (1) RU2482877C2 (cg-RX-API-DMAC7.html)
SG (1) SG177891A1 (cg-RX-API-DMAC7.html)
SI (1) SI2099489T1 (cg-RX-API-DMAC7.html)
WO (1) WO2008073509A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200903489B (cg-RX-API-DMAC7.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20160082T1 (hr) 2006-09-29 2016-02-26 Oncomed Pharmaceuticals, Inc. Sastavi i postupci za dijagnosticiranje i lijeäśenje raka
DK2488204T3 (en) 2009-10-16 2016-06-06 Oncomed Pharm Inc Therapeutic combination and use of DLL4 antagonist antibodies and blood pressure lowering agents
US8551479B2 (en) 2010-09-10 2013-10-08 Oncomed Pharmaceuticals, Inc. Methods for treating melanoma
WO2012088438A1 (en) 2010-12-22 2012-06-28 Eutropics Pharmaceuticals, Inc. Compositions and methods useful for treating diseases
SI3485903T1 (sl) 2011-09-23 2023-02-28 Mereo Biopharma 5, Inc. Sredstva, ki vežejo VEGF/DLL4, in njihove uporabe
AU2013232208B2 (en) * 2012-03-14 2017-04-27 Indiana University Research And Technology Corporation Compounds and methods for treating leukemia
CA2889638A1 (en) 2012-10-31 2014-05-08 Oncomed Pharmaceuticals, Inc. Methods and monitoring of treatment with a dll4 antagonist
GB201409471D0 (en) * 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
CA2966042A1 (en) 2014-10-31 2016-05-06 Oncomed Pharmaceuticals, Inc. Combination therapy for treatment of disease
RU2697665C1 (ru) 2015-07-27 2019-08-16 Чонг Кун Данг Фармасьютикал Корп. Производные 1,3,4-оксадиазолсульфонамида в качестве ингибиторов деацетилазы гистонов 6 и фармацевтическая композиция, содержащая их
KR101799009B1 (ko) 2015-07-27 2017-11-17 주식회사 종근당 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 아마이드 유도체 화합물 및 이를 포함하는 약제학적 조성물
MY194018A (en) 2015-07-27 2022-11-08 Chong Kun Dang Pharmaceutical Corp 1,3,4-oxadiazole sulfamide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same
EP3331864B1 (en) 2015-08-04 2021-11-03 Chong Kun Dang Pharmaceutical Corp. 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same
AU2016326609B2 (en) 2015-09-23 2023-03-09 Mereo Biopharma 5, Inc. Methods and compositions for treatment of cancer
AU2016338118B2 (en) 2015-10-12 2019-03-14 Chong Kun Dang Pharmaceutical Corp. Oxadiazole amine derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
EA202091786A1 (ru) 2018-01-26 2020-10-20 Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния Способы и композиции для лечения ангиогенных расстройств с применением агентов против фрэс
KR102316234B1 (ko) 2018-07-26 2021-10-22 주식회사 종근당 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물
JP7451569B2 (ja) 2019-05-31 2024-03-18 チョン クン ダン ファーマシューティカル コーポレーション ヒストン脱アセチル化酵素6阻害剤としての1,3,4-オキサジアゾールホモフタルイミド誘導体化合物、およびそれを含む薬剤学的組成物
MX2022006241A (es) 2019-11-25 2022-08-22 Univ California Inhibidores de vegf de accion prolongada para la neovascularizacion intraocular.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635517B1 (en) * 1996-07-24 1999-06-29 Celgene Corp Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines
US6281230B1 (en) * 1996-07-24 2001-08-28 Celgene Corporation Isoindolines, method of use, and pharmaceutical compositions
SE9704545D0 (sv) * 1997-12-05 1997-12-05 Astra Pharma Prod Novel compounds
US6169106B1 (en) * 1998-04-15 2001-01-02 Boehringer Ingelheim Pharma Kg Indolinones having kinase inhibitory activity
EE200100184A (et) * 1998-09-25 2002-08-15 Boehringer Ingelheim Pharma Kg Uudsed asendatud indolinoonid inhibeeriva toimegamitmesugustele kinaasidele ja tsükliin/CDK kompleksidele
US6762180B1 (en) * 1999-10-13 2004-07-13 Boehringer Ingelheim Pharma Kg Substituted indolines which inhibit receptor tyrosine kinases
US6638965B2 (en) * 2000-11-01 2003-10-28 Boehringer Ingelheim Pharma Kg Substituted indolinones, preparation thereof and their use as pharmaceutical compositions
US7323479B2 (en) * 2002-05-17 2008-01-29 Celgene Corporation Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline
US7758859B2 (en) * 2003-08-01 2010-07-20 Genentech, Inc. Anti-VEGF antibodies
US20050106667A1 (en) * 2003-08-01 2005-05-19 Genentech, Inc Binding polypeptides with restricted diversity sequences
TWI468417B (zh) * 2007-11-30 2015-01-11 Genentech Inc 抗-vegf抗體

Also Published As

Publication number Publication date
WO2008073509A3 (en) 2009-01-08
JP2010512407A (ja) 2010-04-22
MX2009006202A (es) 2009-06-22
HK1131064A1 (en) 2010-01-15
KR101320198B1 (ko) 2013-10-30
IL198852A0 (en) 2011-08-01
DK2099489T3 (da) 2014-08-18
RU2009126588A (ru) 2011-01-20
BRPI0717688A2 (pt) 2013-01-22
RU2482877C2 (ru) 2013-05-27
EP2099489A2 (en) 2009-09-16
SI2099489T1 (sl) 2014-09-30
CN101547705A (zh) 2009-09-30
CN101547705B (zh) 2013-06-12
WO2008073509A2 (en) 2008-06-19
SG177891A1 (en) 2012-02-28
KR20090087908A (ko) 2009-08-18
NZ577058A (en) 2012-04-27
CA2670707A1 (en) 2008-06-19
US20100086544A1 (en) 2010-04-08
IL198852A (en) 2013-06-27
ZA200903489B (en) 2010-08-25
EP2099489B1 (en) 2014-05-21

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MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted