JP2010511616A - 水素化ピリド（４，３−ｂ）インドール（異性体）に基づいた認知機能および記憶を改善するための手段、当該手段に基づいた薬理学的手段、および当該手段の使用のための方法 - Google Patents
水素化ピリド（４，３−ｂ）インドール（異性体）に基づいた認知機能および記憶を改善するための手段、当該手段に基づいた薬理学的手段、および当該手段の使用のための方法 Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006142521/15A RU2334514C1 (ru) | 2006-12-01 | 2006-12-01 | СРЕДСТВО ДЛЯ УЛУЧШЕНИЯ КОГНИТИВНЫХ ФУНКЦИЙ И ПАМЯТИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО (4,3-b) ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ |
| PCT/US2007/024623 WO2008069963A1 (en) | 2006-12-01 | 2007-11-30 | Means for improving cognitive functions and memory based on hydrogenated pyrido (4,3-b) indoles (variants), pharmacological means based thereon and method for the use thereof |
Publications (2)
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|---|---|
| JP2010511616A true JP2010511616A (ja) | 2010-04-15 |
| JP2010511616A5 JP2010511616A5 (enExample) | 2011-01-20 |
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| JP2009539340A Pending JP2010511616A (ja) | 2006-12-01 | 2007-11-30 | 水素化ピリド（４，３−ｂ）インドール（異性体）に基づいた認知機能および記憶を改善するための手段、当該手段に基づいた薬理学的手段、および当該手段の使用のための方法 |
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| Country | Link |
|---|---|
| US (1) | US20100286188A1 (enExample) |
| EP (1) | EP2101579A4 (enExample) |
| JP (1) | JP2010511616A (enExample) |
| AU (1) | AU2007328323A1 (enExample) |
| CA (1) | CA2671321A1 (enExample) |
| RU (1) | RU2334514C1 (enExample) |
| WO (1) | WO2008069963A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010523556A (ja) * | 2007-04-05 | 2010-07-15 | アンドレイ・アレクサンドロビッチ・イワシェンコ | 置換された２，３，４，５−テトラヒドロ−１ｈ−ピリド［４，３−ｂ］インドール、その製造のための方法及び使用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008302751A1 (en) | 2007-09-20 | 2009-03-26 | D2E, Llc | Fluoro-containing derivatives of hydrogenated pyrido[4,3-b]indoles with neuroprotective and cognition enhancing properties, process for preparing, and use |
| RU2007139634A (ru) | 2007-10-25 | 2009-04-27 | Сергей Олегович Бачурин (RU) | Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения |
| RU2544856C2 (ru) | 2008-01-25 | 2015-03-20 | Сергей Олегович Бачурин | НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
| TWI450900B (zh) | 2008-03-24 | 2014-09-01 | Medivation Technologies Inc | 橋聯雜環化合物及使用方法 |
| TWI443098B (zh) | 2008-03-24 | 2014-07-01 | Medivation Technologies Inc | 吡啶并〔３，４－ｂ〕吲哚及使用方法 |
| CN102316732B (zh) | 2008-10-31 | 2015-04-01 | 梅迪维新技术公司 | 氮杂*并[4,5-b]吲哚以及使用方法 |
| AR073923A1 (es) * | 2008-10-31 | 2010-12-09 | Medivation Technologies Inc | Pirido( 4,3-b) indoles que contienen restos rigidos |
| US9125898B2 (en) * | 2008-11-14 | 2015-09-08 | Neurotune Ag | Acetam derivatives for pain relief |
| AU2010214101A1 (en) | 2009-02-11 | 2011-09-01 | Sunovion Pharmaceuticals Inc. | Histamine H3 inverse agonists and antagonists and methods of use thereof |
| EP2236159A3 (en) * | 2009-03-31 | 2011-12-07 | Sanovel Ilac Sanayi ve Ticaret A.S. | Modified release dimebolin compositions |
| EP2236160A3 (en) * | 2009-03-31 | 2011-12-14 | Sanovel Ilac Sanayi ve Ticaret A.S. | Modified release dimebolin formulations |
| CN102395369A (zh) * | 2009-04-10 | 2012-03-28 | 中国人民解放军军事医学科学院毒物药物研究所 | 含有四氢吡啶[4，3-b]吲哚衍生物的缓释组合物及该衍生物的制备方法 |
| TR200903014A1 (tr) * | 2009-04-17 | 2010-11-22 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Oral yolla dağılan dimebolin bileşimleri. |
| WO2010127177A1 (en) | 2009-04-29 | 2010-11-04 | Medivation Technologies, Inc. | Pyrido [4,3-b] indoles and methods of use |
| WO2011019417A1 (en) | 2009-04-29 | 2011-02-17 | Medivation Technologies, Inc. | Pyrido [4, 3-b] indoles and methods of use |
| JP2013504580A (ja) * | 2009-09-11 | 2013-02-07 | スノヴィオン ファーマシューティカルズ インコーポレイテッド | ヒスタミンｈ３インバースアゴニストおよびアンタゴニストとその使用方法 |
| CN102711466A (zh) * | 2009-09-23 | 2012-10-03 | 梅迪维新技术公司 | 桥连杂环化合物及其使用方法 |
| WO2011038161A1 (en) | 2009-09-23 | 2011-03-31 | Medivation Technologies, Inc. | Pyrido[4,3-b]indoles and methods of use |
| AU2010298168B2 (en) | 2009-09-23 | 2015-11-19 | Medivation Technologies, Inc. | Pyrido(3,4-b)indoles and methods of use |
| RU2428185C1 (ru) * | 2009-12-29 | 2011-09-10 | Учреждение Российской Академии Наук Институт Физиологически Активных Веществ Ран (Ифав Ран) | ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ ДЛЯ ЛЕЧЕНИЯ НЕЙРОДЕГЕНЕРАТИВНЫХ ЗАБОЛЕВАНИЙ НА ОСНОВЕ ГИДРИРОВАННОГО ПИРИДО(4,3-b)ИНДОЛА, СПОСОБ ЕЕ ПОЛУЧЕНИЯ И ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕЕ ОСНОВЕ |
| US9193728B2 (en) | 2010-02-18 | 2015-11-24 | Medivation Technologies, Inc. | Fused tetracyclic pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use |
| US9040519B2 (en) | 2010-02-18 | 2015-05-26 | Medivation Technologies, Inc. | Fused tetracyclic pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use |
| US9034865B2 (en) | 2010-02-18 | 2015-05-19 | Medivation Technologies, Inc. | Pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use |
| US9187471B2 (en) | 2010-02-19 | 2015-11-17 | Medivation Technologies, Inc. | Pyrido [4,3-b] indole and pyrido [3,4-b] indole derivatives and methods of use |
| WO2012016708A1 (en) | 2010-08-06 | 2012-02-09 | Ratiopharm Gmbh | Oral dosage form comprising dimebolin and donepezil |
| WO2012016707A2 (en) * | 2010-08-06 | 2012-02-09 | Ratiopharm Gmbh | Oral dosage form for the modified release of dimebolin |
| WO2012112965A1 (en) | 2011-02-18 | 2012-08-23 | Medivation Technologies, Inc. | Compounds and methods of treating diabetes |
| US20140155384A1 (en) | 2011-02-18 | 2014-06-05 | Medivation Technologies, Inc. | Compounds and methods of treating diabetes |
| CA2829045A1 (en) | 2011-02-18 | 2012-08-23 | Medivation Technologies, Inc. | Compounds and methods for treatment of hypertension |
| WO2012112964A2 (en) | 2011-02-18 | 2012-08-23 | Medivation Technologies, Inc. | PYRIDO[4,3-b]INDOLE AND PYRIDO[3,4-b]INDOLE DERIVATIVES AND METHODS OF USE |
| RU2482843C2 (ru) * | 2011-05-23 | 2013-05-27 | Федеральное Медико-Биологическое Агентство Федеральное Государственное Учреждение Научно-исследовательский институт детских инфекций | Способ реабилитации неврологических нарушений у детей при нейроинфекциях |
| RU2477131C1 (ru) * | 2012-01-17 | 2013-03-10 | Алиса Владимировна Алесенко | СРЕДСТВО ДЛЯ НЕЙТРАЛИЗАЦИИ ТОКСИЧЕСКОГО ДЕЙСТВИЯ ФАКТОРА НЕКРОЗА ОПУХОЛИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО (4,3-b) ИНДОЛОВ, ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЛЕЧЕНИЯ АУТОИММУННЫХ ЗАБОЛЕВАНИЙ НА ОСНОВЕ НЕЙТРАЛИЗАЦИИ ТОКСИЧЕСКОГО ДЕЙСТВИЯ ФАКТОРА НЕКРОЗА ОПУХОЛИ |
| DE102012003065A1 (de) * | 2012-02-13 | 2013-08-14 | Friedrich-Schiller-Universität Jena | Neue bivalente Gammacarbolinderivate sowie deren Herstellung und Verwendung als Antidementiva |
| RU2672728C1 (ru) * | 2017-09-19 | 2018-11-19 | Игорь Анатольевич Помыткин | Холиновые соли фумаровой кислоты |
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| JP2010507672A (ja) * | 2006-10-27 | 2010-03-11 | メディベイション ニューロロジー， インコーポレイテッド | アルツハイマー病を治療するための方法および組み合わせ治療 |
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| RU2140417C1 (ru) * | 1995-10-17 | 1999-10-27 | Институт физиологически активных веществ РАН | Производные гидрированных пиридо(4,3-b)индолов, способы их получения, фармацевтическая композиция и способ лечения |
| RU2106864C1 (ru) * | 1995-10-23 | 1998-03-20 | Николай Серафимович Зефиров | Средство для лечения болезни альцгеймера |
| RU2283108C2 (ru) * | 2003-12-08 | 2006-09-10 | Сергей Олегович Бачурин | ГЕРОПРОТЕКТОР НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b) ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ |
| PL1831227T3 (pl) * | 2004-12-17 | 2013-10-31 | Glenmark Pharmaceuticals Sa | Nowe związki heterocykliczne użyteczne w leczeniu stanów zapalnych i dolegliwości alergicznych |
| MX2009012788A (es) * | 2007-05-25 | 2010-01-14 | Medivation Neurology Inc | Metodos y composiciones para estimular celulas. |
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2006
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2007
- 2007-11-30 EP EP07862370A patent/EP2101579A4/en not_active Withdrawn
- 2007-11-30 JP JP2009539340A patent/JP2010511616A/ja active Pending
- 2007-11-30 WO PCT/US2007/024623 patent/WO2008069963A1/en not_active Ceased
- 2007-11-30 US US12/517,191 patent/US20100286188A1/en not_active Abandoned
- 2007-11-30 CA CA002671321A patent/CA2671321A1/en not_active Abandoned
- 2007-11-30 AU AU2007328323A patent/AU2007328323A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010507672A (ja) * | 2006-10-27 | 2010-03-11 | メディベイション ニューロロジー， インコーポレイテッド | アルツハイマー病を治療するための方法および組み合わせ治療 |
Non-Patent Citations (4)
| Title |
|---|
| JPN6012058790; Ｂｕｌｌｅｔｉｎ ｏｆ Ｅｘｐｅｒｉｍｅｎｔａｌ Ｂｉｏｌｏｇｙ ａｎｄ Ｍｅｄｉｃｉｎｅ Ｖｏｌ．１３２， Ｎｏ．５, 2001, ｐ．１０７９-１０８３ * |
| JPN6012058792; Ｂｕｌｌｅｔｉｎ ｏｆ Ｅｘｐｅｒｉｍｅｎｔａｌ Ｂｉｏｌｏｇｙ ａｎｄ Ｍｅｄｉｃｉｎｅ Ｖｏｌ．１２９， Ｎｏ．６, 2000, ｐ．５４４-５４６ * |
| JPN6012058794; Ａｎｎａｌｓ Ｎｅｗ Ｙｏｒｋ Ａｃａｄｅｍｙ ｏｆ Ｓｃｉｅｎｃｅｓ Ｖｏｌ．９３９, 2001, ｐ．４２５-４３５ * |
| JPN6012058796; Ｔｈｅ Ｌａｎｃｅｔ Ｎｅｕｒｏｌｏｇｙ Ｖｏｌ．２, 2003, ｐ．５３９-５４７ * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010523556A (ja) * | 2007-04-05 | 2010-07-15 | アンドレイ・アレクサンドロビッチ・イワシェンコ | 置換された２，３，４，５−テトラヒドロ−１ｈ−ピリド［４，３−ｂ］インドール、その製造のための方法及び使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20100286188A1 (en) | 2010-11-11 |
| AU2007328323A1 (en) | 2008-06-12 |
| CA2671321A1 (en) | 2008-06-12 |
| WO2008069963A1 (en) | 2008-06-12 |
| EP2101579A4 (en) | 2011-05-18 |
| RU2334514C1 (ru) | 2008-09-27 |
| RU2006142521A (ru) | 2008-06-20 |
| EP2101579A1 (en) | 2009-09-23 |
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