JP2010510492A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010510492A5 JP2010510492A5 JP2009537357A JP2009537357A JP2010510492A5 JP 2010510492 A5 JP2010510492 A5 JP 2010510492A5 JP 2009537357 A JP2009537357 A JP 2009537357A JP 2009537357 A JP2009537357 A JP 2009537357A JP 2010510492 A5 JP2010510492 A5 JP 2010510492A5
- Authority
- JP
- Japan
- Prior art keywords
- fluorescent probe
- targets
- fluorescent
- sample
- bound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/560,599 | 2006-11-16 | ||
| US11/560,599 US7629125B2 (en) | 2006-11-16 | 2006-11-16 | Sequential analysis of biological samples |
| US11/864,093 | 2007-09-28 | ||
| US11/864,093 US7741046B2 (en) | 2006-11-16 | 2007-09-28 | Sequential analysis of biological samples |
| PCT/US2007/084791 WO2008133729A2 (en) | 2006-11-16 | 2007-11-15 | Sequential analysis of biological samples with intermediate bleaching of fluorescence detector |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010510492A JP2010510492A (ja) | 2010-04-02 |
| JP2010510492A5 true JP2010510492A5 (enExample) | 2011-01-06 |
| JP5123314B2 JP5123314B2 (ja) | 2013-01-23 |
Family
ID=39432912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009537357A Expired - Fee Related JP5123314B2 (ja) | 2006-11-16 | 2007-11-15 | 生体試料の連続分析 |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US7629125B2 (enExample) |
| EP (3) | EP2082239B1 (enExample) |
| JP (1) | JP5123314B2 (enExample) |
| AT (2) | ATE524736T1 (enExample) |
| AU (1) | AU2007352364B2 (enExample) |
| CA (1) | CA2669317C (enExample) |
| DK (2) | DK2082230T3 (enExample) |
| ES (3) | ES2371507T3 (enExample) |
| PL (2) | PL2082239T3 (enExample) |
| PT (2) | PT2082230E (enExample) |
| WO (2) | WO2008133729A2 (enExample) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080032321A1 (en) * | 2006-08-07 | 2008-02-07 | General Electric Company | System and methods for analyzing images of tissue samples |
| US8060348B2 (en) * | 2006-08-07 | 2011-11-15 | General Electric Company | Systems for analyzing tissue samples |
| US8131476B2 (en) * | 2006-08-07 | 2012-03-06 | General Electric Company | System and method for co-registering multi-channel images of a tissue micro array |
| US9201063B2 (en) | 2006-11-16 | 2015-12-01 | General Electric Company | Sequential analysis of biological samples |
| US7629125B2 (en) | 2006-11-16 | 2009-12-08 | General Electric Company | Sequential analysis of biological samples |
| US8305579B2 (en) | 2006-11-16 | 2012-11-06 | Thomas Pirrie Treynor | Sequential analysis of biological samples |
| US20100279272A1 (en) * | 2008-02-13 | 2010-11-04 | Michael Craig Burrell | Multiplexed analysis methods using sers-active nanoparticles |
| WO2010085548A2 (en) * | 2009-01-22 | 2010-07-29 | Li-Cor, Inc. | Single molecule proteomics with dynamic probes |
| US9677125B2 (en) * | 2009-10-21 | 2017-06-13 | General Electric Company | Detection of plurality of targets in biological samples |
| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| US8568991B2 (en) * | 2011-12-23 | 2013-10-29 | General Electric Company | Photoactivated chemical bleaching of dyes |
| US9176032B2 (en) | 2011-12-23 | 2015-11-03 | General Electric Company | Methods of analyzing an H and E stained biological sample |
| CA2867144C (en) * | 2012-03-27 | 2019-07-02 | Ventana Medical Systems, Inc. | Signaling conjugates and methods of use |
| AU2013240137B2 (en) * | 2012-03-30 | 2017-04-20 | Leica Microsystems Cms Gmbh | Methods for generating an image of a biological sample |
| RU2014137129A (ru) | 2012-03-30 | 2016-05-27 | Клариент Дайагностик Сервисез, Инк. | Иммунофлуоресцентный анализ и флуоресцентный анализ нуклеиновых кислот в одном и том же образце |
| US9150907B2 (en) | 2012-04-27 | 2015-10-06 | General Electric Company | Microfluidic flow cell assemblies and method of use |
| CN104412097B (zh) * | 2012-04-27 | 2017-07-07 | 生物辐射实验室股份有限公司 | 无染色剂蛋白定量和标准化 |
| US20150141278A1 (en) * | 2012-05-30 | 2015-05-21 | Clarient Diagnostic Services, Inc. | Multiplexed assay method for lung cancer classification |
| WO2013181418A2 (en) | 2012-05-30 | 2013-12-05 | Clarient Diagnostic Services, Inc. | Multiplexed diagnosis method for classical hodgkin lymphoma |
| US20140024024A1 (en) | 2012-07-17 | 2014-01-23 | General Electric Company | Methods of detecting dna, rna and protein in biological samples |
| US20140055853A1 (en) | 2012-08-27 | 2014-02-27 | General Electric Company | Open top microfluidic device for multiplexing |
| EP3379245A1 (en) | 2012-10-09 | 2018-09-26 | University Of Utah Research Foundation | Monitoring temperature with fluorescence |
| US20150226743A1 (en) | 2012-10-28 | 2015-08-13 | Clarient Diagnostics Services, Inc. | Multiplexed method for diagnosing classical hodgkin lymphoma |
| US9135694B2 (en) | 2012-12-04 | 2015-09-15 | General Electric Company | Systems and methods for using an immunostaining mask to selectively refine ISH analysis results |
| RU2015120176A (ru) * | 2012-12-11 | 2017-01-19 | Клариент Дайагностик Сервисез, Инк. | Фотоактивированное химическое обесцвечивание красителей |
| WO2014099222A1 (en) * | 2012-12-17 | 2014-06-26 | Clarient Diagnostic Services, Inc. | Chemical bleaching of dyes using radical photoinitiators |
| HUE034313T2 (en) | 2012-12-20 | 2018-02-28 | Hoffmann La Roche | Procedures for evaluating medical measurement curves |
| US11306360B2 (en) | 2012-12-26 | 2022-04-19 | Koninklijke Philips N.V. | Assessment of cellular signaling pathway activity using linear combination(s) of target gene expressions |
| US9932626B2 (en) | 2013-01-15 | 2018-04-03 | Quanterix Corporation | Detection of DNA or RNA using single molecule arrays and other techniques |
| WO2014138197A1 (en) | 2013-03-06 | 2014-09-12 | General Electric Company | Methods of analyzing an h&e stained biological sample |
| ES2804300T3 (es) | 2013-03-12 | 2021-02-05 | Ventana Med Syst Inc | Microscopía mejorada digitalmente para histología multiplexada |
| EP2972376B1 (en) * | 2013-03-15 | 2018-12-05 | Eisai Inc. | Methods for determining prognosis of colorectal cancer |
| EP3004372A1 (en) * | 2013-06-04 | 2016-04-13 | Roche Diagnostics GmbH | Novel compounds useful for fret and methods related thereto |
| US9322051B2 (en) | 2013-10-07 | 2016-04-26 | General Electric Company | Probing of biological samples |
| US9778263B2 (en) * | 2013-11-13 | 2017-10-03 | General Electric Company | Quantitative in situ characterization of biological samples |
| US9858469B2 (en) | 2013-12-30 | 2018-01-02 | Ge Healthcare Bio-Sciences Corp. | Modular image analysis system and method |
| US20150198580A1 (en) | 2014-01-13 | 2015-07-16 | General Electric Company | Coverslip and methods for removing |
| ES2968004T3 (es) | 2014-07-30 | 2024-05-06 | Harvard College | Construcción de bibliotecas de sondas |
| US10417247B2 (en) | 2014-09-25 | 2019-09-17 | Oracle International Corporation | Techniques for semantic searching |
| US10664488B2 (en) | 2014-09-25 | 2020-05-26 | Oracle International Corporation | Semantic searches in a business intelligence system |
| US10516980B2 (en) | 2015-10-24 | 2019-12-24 | Oracle International Corporation | Automatic redisplay of a user interface including a visualization |
| US12216673B2 (en) | 2014-09-25 | 2025-02-04 | Oracle International Corporation | Techniques for semantic searching |
| US9708349B2 (en) | 2015-02-13 | 2017-07-18 | General Electric Company | Borates for photoactivated chemical bleaching |
| US10101322B2 (en) | 2015-02-13 | 2018-10-16 | General Electric Company | Photoactivated chemical bleaching of dyes using borates |
| US10839509B2 (en) | 2015-07-10 | 2020-11-17 | 3Scan Inc. | Spatial multiplexing of histological stains |
| US11415516B2 (en) | 2015-10-28 | 2022-08-16 | Leica Microsystems Cms Gmbh | Method for reduction of autofluorescence from biological samples |
| KR20180100607A (ko) * | 2016-01-07 | 2018-09-11 | 크리에티브이 마이크로테크, 인크. | 순차적인 형광 소광 및 재염색을 이용한 생물학적 시료의 다중-표현형적 서브타이핑 |
| WO2017137402A1 (en) * | 2016-02-08 | 2017-08-17 | Lunaphore Technologies Sa | Methods of sample cycle multiplexing and in situ imaging |
| WO2017202962A1 (en) | 2016-05-24 | 2017-11-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of non small cell lung cancer (nsclc) that coexists with chronic obstructive pulmonary disease (copd) |
| JP2020513796A (ja) | 2016-11-16 | 2020-05-21 | ユニバーシティ オブ ワシントンＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｗａｓｈｉｎｇｔｏｎ | サイクリック蛍光イメージングのためのシステムおよび方法 |
| KR102476709B1 (ko) | 2016-11-21 | 2022-12-09 | 나노스트링 테크놀로지스, 인크. | 화학적 조성물 및 이것을 사용하는 방법 |
| WO2018107054A1 (en) | 2016-12-09 | 2018-06-14 | Ultivue, Inc. | Improved methods for multiplex imaging using labeled nucleic acid imaging agents |
| WO2018122245A1 (en) | 2016-12-28 | 2018-07-05 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of predicting the survival time of patients suffering from cms3 colorectal cancer |
| WO2018122249A1 (en) | 2016-12-28 | 2018-07-05 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the survival time of patients suffering from a microsatellite stable colorectal cancer |
| WO2018202850A1 (en) | 2017-05-05 | 2018-11-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Microtubule-targeting drugs as immune checkpoint inhibitors and methods of screening novel immune checkpoint inhibitors for the treatment of cancers and infectious diseases |
| WO2018218150A1 (en) | 2017-05-26 | 2018-11-29 | President And Fellows Of Harvard College | Systems and methods for high-throughput image-based screening |
| US10956237B2 (en) | 2017-06-02 | 2021-03-23 | Oracle International Corporation | Inter-application sharing of business intelligence data |
| US11614857B2 (en) | 2017-06-02 | 2023-03-28 | Oracle International Corporation | Importing, interpreting, and presenting data |
| US10917587B2 (en) | 2017-06-02 | 2021-02-09 | Oracle International Corporation | Importing and presenting data |
| EP3809138B1 (en) * | 2017-06-08 | 2025-02-19 | Lumito AB | A method of analysing a sample for at least one analyte |
| CN109781975B (zh) * | 2017-11-14 | 2022-05-06 | 河南乾坤科技有限公司 | 富集循环稀有细胞的试剂及方法 |
| CN111602136A (zh) | 2018-01-11 | 2020-08-28 | 谷歌有限责任公司 | 使用载玻片重新染色创建组织病理学基准真值掩膜的方法 |
| EP3794146B1 (en) | 2018-05-14 | 2025-12-10 | Bruker Spatial Biology, Inc. | Method for identifying a predetermined nucleotide sequence |
| CN113366116A (zh) | 2018-12-13 | 2021-09-07 | 哈佛学院院长及董事 | 用于merfish和其他应用的扩增方法和系统 |
| EP3906415A1 (en) | 2019-01-03 | 2021-11-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for enhancing cd8+ t cell-dependent immune responses in subjects suffering from cancer |
| WO2020201362A2 (en) | 2019-04-02 | 2020-10-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of predicting and preventing cancer in patients having premalignant lesions |
| WO2020208060A1 (en) | 2019-04-09 | 2020-10-15 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer |
| AU2020288603A1 (en) | 2019-06-03 | 2021-12-16 | Assistance Publique - Hôpitaux De Paris | Methods for modulating a treatment regimen |
| WO2021074391A1 (en) | 2019-10-17 | 2021-04-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosing nasal intestinal type adenocarcinomas |
| EP4110955A1 (en) | 2020-02-28 | 2023-01-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosing, prognosing and managing treatment of breast cancer |
| CN111351946B (zh) * | 2020-03-19 | 2023-08-18 | 中南大学湘雅二医院 | 用于红斑狼疮分型的AIM2+CD4+Trm细胞检测试剂盒及其应用 |
| CN115997123A (zh) | 2020-06-30 | 2023-04-21 | 国家医疗保健研究所 | 用于预测实体癌患者在术前辅助治疗后复发和/或死亡风险的方法 |
| JP7741831B2 (ja) | 2020-06-30 | 2025-09-18 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 術前補助療法及び根治手術後の固形がんを患っている患者の再発及び／又は死亡のリスクを予測するための方法 |
| US20220062898A1 (en) | 2020-08-28 | 2022-03-03 | Leica Microsystems Cms Gmbh | Microfluidic Device for Image Multiplexing |
| US20240175873A1 (en) | 2021-03-23 | 2024-05-30 | Institut National de la Santé et de la Recherche Médicale | Methods for the diagnosis and treatment of t cell-lymphomas |
| WO2022225845A1 (en) * | 2021-04-18 | 2022-10-27 | Mary Hitchcock Memorial Hospital, For Itself And On Behalf Of Dartmouth-Hitchcock Clinic | System and method for automation of surgical pathology processes using artificial intelligence |
| EP4341670A1 (en) * | 2021-05-19 | 2024-03-27 | Leica Microsystems CMS GmbH | Method and device for analyzing a biological sample |
| CA3228621A1 (en) * | 2021-08-09 | 2023-02-16 | Xin Huang | Compositions, kits, and methods for detecting preclinical alzheimer's disease |
| EP4472740A1 (en) | 2022-01-31 | 2024-12-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Cd38 as a biomarker and biotarget in t-cell lymphomas |
| US20250035635A1 (en) | 2022-03-17 | 2025-01-30 | Institut National De La Sante Et De La Recherche Medicale | Methods for predicting response to an immunotherapeutic treatment in a patient with a cancer |
| JP2025514669A (ja) | 2022-04-11 | 2025-05-09 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | Ｔ細胞悪性腫瘍の診断及び処置のための方法 |
| WO2023198874A1 (en) | 2022-04-15 | 2023-10-19 | Institut National de la Santé et de la Recherche Médicale | Methods for the diagnosis and treatment of t cell-lymphomas |
| WO2024003310A1 (en) | 2022-06-30 | 2024-01-04 | Institut National de la Santé et de la Recherche Médicale | Methods for the diagnosis and treatment of acute lymphoblastic leukemia |
| JP2025526336A (ja) | 2022-07-22 | 2025-08-13 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | Ｔ細胞悪性腫瘍におけるバイオマーカー及びバイオターゲットとしてのｇａｒｐ |
| WO2024023283A1 (en) | 2022-07-29 | 2024-02-01 | Institut National de la Santé et de la Recherche Médicale | Lrrc33 as a biomarker and biotarget in cutaneous t-cell lymphomas |
| EP4602372A1 (en) | 2022-10-12 | 2025-08-20 | Institut National de la Santé et de la Recherche Médicale | Cd81 as a biomarker and biotarget in t-cell malignancies |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4405720A (en) | 1981-03-04 | 1983-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | Silver stains for protein in gels |
| GB8405437D0 (en) | 1984-03-01 | 1984-04-04 | Amersham Int Plc | Detecting polynucleotide sequences |
| JP3130513B2 (ja) * | 1989-04-19 | 2001-01-31 | イビデン株式会社 | 生体活性物質測定用装置 |
| US5843640A (en) | 1992-06-19 | 1998-12-01 | Northwestern University | Method of simultaneously detecting amplified nucleic acid sequences and cellular antigens in cells |
| WO1994009022A1 (en) | 1992-10-09 | 1994-04-28 | Oncor, Inc. | Methods for the detection of chromosome structural abnormalities by in situ hybridization to fixed tissue |
| AU7401394A (en) | 1993-07-20 | 1995-02-20 | University Of Massachusetts Medical Center | In vivo nucleic acid hybridization method |
| FR2711671A1 (fr) | 1993-10-22 | 1995-05-05 | Centre Nat Rech Scient | Procédé de détection et de quantification d'une séquence nucléotidique dans une population cellulaire. |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| DE4421891C2 (de) | 1994-06-23 | 1996-05-15 | Helmut Prof Dr Med Feucht | Verfahren zum Nachweis von komplementaktivierenden IgG-Antikörpern gegen HLA-DR-Antigene |
| US5571643A (en) | 1994-07-22 | 1996-11-05 | Martin; Mark T. | Spectrophotometric quantitation of images in X-ray film and electrophoresis gel bands |
| ATE340866T1 (de) | 1994-10-28 | 2006-10-15 | Gen Probe Inc | Zusammensetzungen und verfahren für die gleichzeitige detektion und quantifizierung von einer mehrheit spezifischer nuklein säure sequenzen |
| US5830645A (en) | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
| US5763152A (en) | 1995-03-31 | 1998-06-09 | Fuji Photo Film Co., Ltd. | Silver halide photographic light-sensitive material |
| EP0801306A1 (en) | 1996-04-10 | 1997-10-15 | Becton, Dickinson and Company | Method for immunohistochemically quantitating co-localized molecules |
| DE19709348C2 (de) * | 1996-05-29 | 1999-07-01 | Schubert Walter Dr Md | Automatisches Multi-Epitop-Ligand-Kartierungsverfahren |
| WO1998002577A1 (en) | 1996-07-15 | 1998-01-22 | The Children's Medical Center Corporation | Method to co-detect introduced genes and their products |
| US6735531B2 (en) * | 1996-10-07 | 2004-05-11 | Lab Vision Corporation | Method and apparatus for automatic tissue staining |
| DE19717904A1 (de) * | 1997-04-23 | 1998-10-29 | Diagnostikforschung Inst | Säurelabile und enzymatisch spaltbare Farbstoffkonstrukte zur Diagnostik mit Nahinfrarotlicht und zur Therapie |
| US6068979A (en) * | 1998-04-22 | 2000-05-30 | Lumigen, Inc. | Simplified sequential chemiluminescent detection |
| US6083486A (en) * | 1998-05-14 | 2000-07-04 | The General Hospital Corporation | Intramolecularly-quenched near infrared fluorescent probes |
| JP2002520448A (ja) | 1998-07-10 | 2002-07-09 | クロマジェン インコーポレーティッド | 加水分解酵素の新規蛍光原基質 |
| DE19835284C2 (de) | 1998-08-05 | 2001-03-01 | Tuhh Tech Gmbh | Vorrichtung und Verfahren zur automatischen Fokussierung und Belichtung von Bildaufnahmesystemen |
| US6573043B1 (en) | 1998-10-07 | 2003-06-03 | Genentech, Inc. | Tissue analysis and kits therefor |
| CA2345276C (en) | 1998-10-09 | 2011-03-29 | Ludwig Institute For Cancer Research | Flt4 (vegfr-3) as a target for tumor imaging and anti-tumor therapy |
| US6087112A (en) | 1998-12-30 | 2000-07-11 | Oligos Etc. Inc. | Arrays with modified oligonucleotide and polynucleotide compositions |
| US20020044353A1 (en) * | 1999-02-10 | 2002-04-18 | Salzman David B. | Spintronic optical shutter |
| WO2000058507A1 (en) | 1999-03-30 | 2000-10-05 | Solexa Ltd. | Polynucleotide sequencing |
| US6391649B1 (en) | 1999-05-04 | 2002-05-21 | The Rockefeller University | Method for the comparative quantitative analysis of proteins and other biological material by isotopic labeling and mass spectroscopy |
| EP1218543A2 (en) * | 1999-09-29 | 2002-07-03 | Solexa Ltd. | Polynucleotide sequencing |
| GB0002389D0 (en) * | 2000-02-02 | 2000-03-22 | Solexa Ltd | Molecular arrays |
| DE10014685B4 (de) * | 2000-03-24 | 2004-07-01 | Schubert, Walter, Dr. | Verfahren zur Identifizierung von zellspezifischen Zielstrukturen |
| WO2001086296A2 (en) * | 2000-05-05 | 2001-11-15 | Agilix Corporation | Highly multiplexed reporter carrier systems |
| IL136232A0 (en) | 2000-05-18 | 2001-05-20 | Bar Ilan University Res Author | Measurements of enzymatic activity in a single, individual cell in population |
| US6545758B1 (en) * | 2000-08-17 | 2003-04-08 | Perry Sandstrom | Microarray detector and synthesizer |
| US20030044353A1 (en) * | 2001-01-05 | 2003-03-06 | Ralph Weissleder | Activatable imaging probes |
| JP2002323416A (ja) | 2001-02-20 | 2002-11-08 | Hitachi Ltd | 検査容器 |
| US20050230255A1 (en) | 2001-03-30 | 2005-10-20 | Sumner Lloyd W | Silver destaining method |
| US7219016B2 (en) * | 2001-04-20 | 2007-05-15 | Yale University | Systems and methods for automated analysis of cells and tissues |
| US20020173053A1 (en) * | 2001-04-27 | 2002-11-21 | Bassam Damaj | Multiple simultaneous antigen detection by immunohistochemistry |
| JP3899845B2 (ja) | 2001-05-23 | 2007-03-28 | 日本光電工業株式会社 | 染色標本の脱色方法および装置 |
| US20040219551A1 (en) * | 2001-07-09 | 2004-11-04 | Petersen Ole William | Epsti1, a novel gene induced by epithelial-stromal interaction in human breast cancer |
| US20040241688A1 (en) * | 2001-07-19 | 2004-12-02 | Cuneyt Bukusoglu | Human tissue specific drug screening procedure |
| DE10143757A1 (de) | 2001-09-06 | 2003-03-27 | Werner M | Methode zur Darstellung von Merkmalen in Geweben |
| US8323903B2 (en) * | 2001-10-12 | 2012-12-04 | Life Technologies Corporation | Antibody complexes and methods for immunolabeling |
| WO2003061711A2 (en) * | 2002-01-16 | 2003-07-31 | Visen Medical, Inc. | Chromophore probes for optical imaging |
| US6731831B2 (en) | 2002-02-27 | 2004-05-04 | Xiang Zheng Tu | Optical switch array assembly for DNA probe synthesis and detection |
| US7166478B2 (en) * | 2002-03-12 | 2007-01-23 | Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. | Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses |
| US7776195B2 (en) * | 2002-05-28 | 2010-08-17 | Autogenomics, Inc. | Integrated sample processing platform |
| JP2004041121A (ja) * | 2002-07-12 | 2004-02-12 | Hitachi Ltd | アレルギー解析方法及びシステム |
| WO2004061131A1 (en) * | 2002-12-18 | 2004-07-22 | Aclara Biosciences, Inc. | Multiplexed immunohistochemical assays using molecular tags |
| US20040241776A1 (en) | 2003-05-22 | 2004-12-02 | Agdia, Inc. | Multiplex enzyme-linked immunosorbent assay for detecting multiple analytes |
| JP3936689B2 (ja) * | 2003-09-09 | 2007-06-27 | 日本碍子株式会社 | シアニン系有機色素劣化環境の検知方法 |
| US7463778B2 (en) | 2004-01-30 | 2008-12-09 | Hewlett-Packard Development Company, L.P | Motion estimation for compressing multiple view images |
| JP4538628B2 (ja) | 2004-03-16 | 2010-09-08 | 学校法人慶應義塾 | 遺伝子発現検出方法 |
| JP4189495B2 (ja) * | 2004-08-02 | 2008-12-03 | 国立大学法人群馬大学 | ゲノムｄｎａのメチル化検出方法 |
| EP3257949A1 (en) * | 2005-06-15 | 2017-12-20 | Complete Genomics Inc. | Nucleic acid analysis by random mixtures of non-overlapping fragments |
| JP2007033159A (ja) * | 2005-07-25 | 2007-02-08 | Assay Corp | 蛍光分子で標識された測定対象物質 |
| JPWO2007055302A1 (ja) * | 2005-11-10 | 2009-04-30 | 国立大学法人富山大学 | 生体物質と生体物質結合性物質との結合性評価方法 |
| US7741045B2 (en) * | 2006-11-16 | 2010-06-22 | General Electric Company | Sequential analysis of biological samples |
| US8305579B2 (en) * | 2006-11-16 | 2012-11-06 | Thomas Pirrie Treynor | Sequential analysis of biological samples |
| US7629125B2 (en) | 2006-11-16 | 2009-12-08 | General Electric Company | Sequential analysis of biological samples |
-
2006
- 2006-11-16 US US11/560,599 patent/US7629125B2/en active Active
-
2007
- 2007-09-28 US US11/864,093 patent/US7741046B2/en active Active
- 2007-11-15 AU AU2007352364A patent/AU2007352364B2/en not_active Ceased
- 2007-11-15 PT PT07874282T patent/PT2082230E/pt unknown
- 2007-11-15 WO PCT/US2007/084791 patent/WO2008133729A2/en not_active Ceased
- 2007-11-15 WO PCT/US2007/084783 patent/WO2008133727A2/en not_active Ceased
- 2007-11-15 EP EP07874284A patent/EP2082239B1/en active Active
- 2007-11-15 ES ES07874284T patent/ES2371507T3/es active Active
- 2007-11-15 JP JP2009537357A patent/JP5123314B2/ja not_active Expired - Fee Related
- 2007-11-15 CA CA2669317A patent/CA2669317C/en active Active
- 2007-11-15 ES ES07871481T patent/ES2371290T3/es active Active
- 2007-11-15 DK DK07874282.2T patent/DK2082230T3/da active
- 2007-11-15 EP EP11175305.9A patent/EP2383574B1/en active Active
- 2007-11-15 AT AT07874282T patent/ATE524736T1/de active
- 2007-11-15 AT AT07874284T patent/ATE524742T1/de active
- 2007-11-15 PL PL07874284T patent/PL2082239T3/pl unknown
- 2007-11-15 ES ES07874282T patent/ES2371506T3/es active Active
- 2007-11-15 PT PT07874284T patent/PT2082239E/pt unknown
- 2007-11-15 PL PL07874282T patent/PL2082230T3/pl unknown
- 2007-11-15 EP EP07874282A patent/EP2082230B1/en active Active
- 2007-11-15 DK DK07874284.8T patent/DK2082239T3/da active
-
2009
- 2009-11-03 US US12/611,299 patent/US9518982B2/en not_active Expired - Fee Related
-
2012
- 2012-04-27 US US13/457,531 patent/US8822147B2/en active Active
-
2013
- 2013-10-23 US US14/060,650 patent/US20140045251A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010510492A5 (enExample) | ||
| JP2010510493A5 (enExample) | ||
| JP2010520989A5 (enExample) | ||
| ATE520026T1 (de) | Sequenzielle analyse biologischer proben | |
| ATE541215T1 (de) | Sequenzielle analyse biologischer proben mit zwischenbleichung eines fluoreszenzdetektors | |
| MX2010010465A (es) | Metodo para la deteccion de igf1r/chr 15 en celulas tumorales circulantes mediante hibridacion fluorescente in situ. | |
| CN106092982B (zh) | 癌细胞及细胞表面多糖检测荧光/比色双模式纸芯片的制备 | |
| WO2008133729A3 (en) | Sequential analysis of biological samples with intermediate bleaching of fluorescence detector | |
| KR20170104154A (ko) | 샘플과 연관된 폴리뉴클레오티드의 식별 | |
| Chao et al. | A rapid and portable sensor based on protein-modified gold nanoparticle probes and lateral flow assay for naked eye detection of mercury ion | |
| CN110455756B (zh) | 一种同时检测二价铅离子和二价铜离子的方法 | |
| ATE549624T1 (de) | Verfahren und zusammensetzungen zur diagnose und behandlung von grippe | |
| JP2009515553A5 (enExample) | ||
| JP2009524829A5 (enExample) | ||
| JP2014507949A5 (enExample) | ||
| JP2012524523A5 (enExample) | ||
| Zhao et al. | Application of recombinase polymerase amplification with lateral flow assay to pathogen point-of-care diagnosis | |
| ATE529533T1 (de) | Verfahren zum nachweis von analyten in einer probe | |
| Liu et al. | A dual DNA tetrahedrons and MnO2 nanosheets sustained entropy-driven DNA amplifier enables high-performance operation in live cells and bodies under a light-gated manner | |
| Lu et al. | Exonuclease III-assisted CRISPR/Cas12a electrochemical biosensor for detection of transcription factor binding catalytic hairpin assembly signal amplification technology | |
| JP2003530118A5 (enExample) | ||
| Shav-Tal et al. | Gene expression within a dynamic nuclear landscape | |
| JP2012050391A5 (enExample) | ||
| JP2011523847A5 (enExample) | ||
| CN119391829A (zh) | 基于dna四面体链置换反应的端粒酶检测组合物、试剂盒及系统 |