JP2010508285A5 - - Google Patents
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- Publication number
- JP2010508285A5 JP2010508285A5 JP2009534841A JP2009534841A JP2010508285A5 JP 2010508285 A5 JP2010508285 A5 JP 2010508285A5 JP 2009534841 A JP2009534841 A JP 2009534841A JP 2009534841 A JP2009534841 A JP 2009534841A JP 2010508285 A5 JP2010508285 A5 JP 2010508285A5
- Authority
- JP
- Japan
- Prior art keywords
- ester
- sucrose
- btc
- dmf
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/552,789 US8258291B2 (en) | 2006-10-25 | 2006-10-25 | Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC) |
| PCT/US2007/082422 WO2008052076A2 (en) | 2006-10-25 | 2007-10-24 | Process for the preparation of sucralose by the chlorination of sugar with triphosgene (btc) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010508285A JP2010508285A (ja) | 2010-03-18 |
| JP2010508285A5 true JP2010508285A5 (https=) | 2011-01-20 |
Family
ID=39325402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009534841A Pending JP2010508285A (ja) | 2006-10-25 | 2007-10-24 | トリホスゲン（ｂｔｃ）を用いた糖の塩素化によるスクラロースの製造方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8258291B2 (https=) |
| EP (1) | EP2094873B1 (https=) |
| JP (1) | JP2010508285A (https=) |
| KR (1) | KR20090082422A (https=) |
| CN (1) | CN101631878A (https=) |
| AT (1) | ATE515509T1 (https=) |
| AU (1) | AU2007308947A1 (https=) |
| BR (1) | BRPI0718178A2 (https=) |
| CA (1) | CA2667419A1 (https=) |
| CY (1) | CY1112434T1 (https=) |
| DK (1) | DK2094873T3 (https=) |
| ES (1) | ES2366063T3 (https=) |
| MX (1) | MX2009004355A (https=) |
| PL (1) | PL2094873T3 (https=) |
| PT (1) | PT2094873E (https=) |
| RU (1) | RU2009119515A (https=) |
| SI (1) | SI2094873T1 (https=) |
| TW (1) | TW200833706A (https=) |
| WO (1) | WO2008052076A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080103295A1 (en) * | 2006-10-25 | 2008-05-01 | David Losan Ho | Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst |
| US7862744B2 (en) * | 2008-07-23 | 2011-01-04 | Mamtek International Limited | Methods and systems for preparing materials for sucralose production |
| CA2817630C (en) | 2010-11-23 | 2019-09-03 | Lexington Pharmaceuticals Laboratories, Llc | Low temperature chlorination of carbohydrates |
| US8884004B2 (en) | 2011-09-02 | 2014-11-11 | Divi's Laboratories, Ltd. | Process for the preparation of sucralose |
| MX342969B (es) | 2011-10-14 | 2016-10-20 | Lexington Pharmaceuticals Laboratories Llc | Cloracion de carbohidratos y derivados de carbohidratos. |
| CN103087116A (zh) * | 2011-11-07 | 2013-05-08 | 常茂生物化学工程股份有限公司 | 三氯蔗糖的制备方法 |
| CN104774227A (zh) * | 2015-04-08 | 2015-07-15 | 常州市牛塘化工厂有限公司 | 一种蔗糖-6-乙酯的氯化方法 |
| WO2016194001A1 (en) * | 2015-05-29 | 2016-12-08 | Alaparthi Lakshmi Prasad | Processes for preparation of sugammadex and intermediates thereof |
| CN105111250A (zh) * | 2015-08-28 | 2015-12-02 | 山东康宝生化科技有限公司 | 一种利用固体光气进行三氯蔗糖6乙酯的制备方法 |
| CN105153248A (zh) * | 2015-08-28 | 2015-12-16 | 山东康宝生化科技有限公司 | 在固体光气法合成三氯蔗糖6乙酯过程中的温度控制方法 |
| JP6815932B2 (ja) * | 2017-05-31 | 2021-01-20 | 株式会社トクヤマ | Ｎ−カルバメート保護カルボキシ無水物の製造方法 |
| CN108203452B (zh) * | 2018-01-24 | 2021-04-06 | 山东康宝生化科技有限公司 | 一种合成三氯蔗糖-6-乙酯的方法 |
| CN110950888B (zh) * | 2019-11-11 | 2022-05-20 | 山东省科学院菏泽分院 | 一种Vilsmeier试剂参与的氯噁酮的制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3072725A (en) | 1960-11-14 | 1963-01-08 | Du Pont | Preparation of dimethylformamide |
| EP0043649B1 (en) * | 1980-07-08 | 1984-09-12 | TATE & LYLE PUBLIC LIMITED COMPANY | Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs) |
| GB8818430D0 (en) | 1988-08-03 | 1988-09-07 | Tate & Lyle Plc | Process |
| US4980463A (en) | 1989-07-18 | 1990-12-25 | Noramco, Inc. | Sucrose-6-ester chlorination |
| JP3002885B2 (ja) | 1989-11-02 | 2000-01-24 | 住友化学工業株式会社 | ジメチルホルムアミドの回収精製法 |
| JP3514495B2 (ja) * | 1992-10-02 | 2004-03-31 | エーザイ株式会社 | ハロゲン化アミノチアジアゾリル酢酸誘導体の製造法 |
| CO4410191A1 (es) | 1994-09-19 | 1997-01-09 | Lilly Co Eli | SINTESIS DE 3-[4-(2-AMINOETOXI)BENZOIL]-2-ARIL-6- HIDROXIBENZO [b] TIOFENOS |
| US5498709A (en) | 1994-10-17 | 1996-03-12 | Mcneil-Ppc, Inc. | Production of sucralose without intermediate isolation of crystalline sucralose-6-ester |
| EP1076661A1 (en) * | 1998-05-15 | 2001-02-21 | Rostislav G. Zhbankov | Method of preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose |
| CA2291134C (en) * | 1998-10-20 | 2006-05-23 | H. Lundbeck A/S | Method for the preparation of citalopram |
| US6998480B2 (en) | 2002-03-08 | 2006-02-14 | Tate & Lyle Public Limited Company | Process for improving sucralose purity and yield |
| CN1176094C (zh) | 2003-05-23 | 2004-11-17 | 广东省食品工业研究所 | 一种三氯蔗糖的合成方法 |
| US20060205936A1 (en) | 2005-03-14 | 2006-09-14 | Sl Laboratories, Llc | Chlorination of Sucrose-6-esters |
| KR20080004575A (ko) * | 2005-05-04 | 2008-01-09 | 팜드 메디케어 프리베이트 리미티드 | 염소화 반응을 위한 디(트리클로로메틸)카보네이트 유래의빌스마이어 헥크 시약의 합성 |
| US7951937B2 (en) | 2005-08-30 | 2011-05-31 | V.B. Medicare Private Limited | Process for purification of trichlorogalactosucrose based on direct extraction in organic solvent from reaction mixture followed by evaporative removal of solvent |
| BRPI0711237A2 (pt) | 2006-05-23 | 2011-08-23 | Vb Medicare Pvt Ltd | processo de purificação e recuperação de uma amida terciária a partir de uma composição lìquida aquosa |
| US20080103295A1 (en) | 2006-10-25 | 2008-05-01 | David Losan Ho | Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst |
-
2006
- 2006-10-25 US US11/552,789 patent/US8258291B2/en not_active Expired - Fee Related
-
2007
- 2007-10-19 TW TW096139365A patent/TW200833706A/zh unknown
- 2007-10-24 AT AT07854397T patent/ATE515509T1/de active
- 2007-10-24 BR BRPI0718178-7A2A patent/BRPI0718178A2/pt not_active Application Discontinuation
- 2007-10-24 PT PT07854397T patent/PT2094873E/pt unknown
- 2007-10-24 DK DK07854397.2T patent/DK2094873T3/da active
- 2007-10-24 JP JP2009534841A patent/JP2010508285A/ja active Pending
- 2007-10-24 CA CA002667419A patent/CA2667419A1/en not_active Abandoned
- 2007-10-24 EP EP07854397A patent/EP2094873B1/en not_active Not-in-force
- 2007-10-24 SI SI200730686T patent/SI2094873T1/sl unknown
- 2007-10-24 KR KR1020097010474A patent/KR20090082422A/ko not_active Withdrawn
- 2007-10-24 ES ES07854397T patent/ES2366063T3/es active Active
- 2007-10-24 AU AU2007308947A patent/AU2007308947A1/en not_active Abandoned
- 2007-10-24 RU RU2009119515/04A patent/RU2009119515A/ru not_active Application Discontinuation
- 2007-10-24 WO PCT/US2007/082422 patent/WO2008052076A2/en not_active Ceased
- 2007-10-24 MX MX2009004355A patent/MX2009004355A/es not_active Application Discontinuation
- 2007-10-24 PL PL07854397T patent/PL2094873T3/pl unknown
- 2007-10-24 CN CN200780043677A patent/CN101631878A/zh active Pending
-
2011
- 2011-08-08 CY CY20111100756T patent/CY1112434T1/el unknown
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