JP2010506953A5 - - Google Patents
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- Publication number
- JP2010506953A5 JP2010506953A5 JP2009533511A JP2009533511A JP2010506953A5 JP 2010506953 A5 JP2010506953 A5 JP 2010506953A5 JP 2009533511 A JP2009533511 A JP 2009533511A JP 2009533511 A JP2009533511 A JP 2009533511A JP 2010506953 A5 JP2010506953 A5 JP 2010506953A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- compound
- pharmaceutical composition
- acceptable carrier
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 239000003937 drug carrier Substances 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 230000003780 keratinization Effects 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 206010004146 Basal cell carcinoma Diseases 0.000 claims 2
- 208000003373 basosquamous carcinoma Diseases 0.000 claims 2
- 208000002874 Acne Vulgaris Diseases 0.000 claims 1
- 201000004384 Alopecia Diseases 0.000 claims 1
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical group OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 claims 1
- 201000004624 Dermatitis Diseases 0.000 claims 1
- 208000025309 Hair disease Diseases 0.000 claims 1
- 206010051246 Photodermatosis Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 241001303601 Rosacea Species 0.000 claims 1
- 206010000496 acne Diseases 0.000 claims 1
- 208000009621 actinic keratosis Diseases 0.000 claims 1
- 231100000360 alopecia Toxicity 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 208000034653 disorder of pilosebaceous unit Diseases 0.000 claims 1
- 229940097042 glucuronate Drugs 0.000 claims 1
- 206010021198 ichthyosis Diseases 0.000 claims 1
- 208000026721 nail disease Diseases 0.000 claims 1
- 201000004700 rosacea Diseases 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 0 CCC(CC)[C@](C1=CCC=C(*c2nc3ccccc3[s]2)C=C1)N1N=CN=CC1 Chemical compound CCC(CC)[C@](C1=CCC=C(*c2nc3ccccc3[s]2)C=C1)N1N=CN=CC1 0.000 description 5
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85198906P | 2006-10-17 | 2006-10-17 | |
| US60/851,989 | 2006-10-17 | ||
| PCT/US2007/081685 WO2008049027A1 (en) | 2006-10-17 | 2007-10-17 | Talarazole metabolites |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010506953A JP2010506953A (ja) | 2010-03-04 |
| JP2010506953A5 true JP2010506953A5 (enExample) | 2010-09-16 |
| JP5343267B2 JP5343267B2 (ja) | 2013-11-13 |
Family
ID=39314359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009533511A Expired - Fee Related JP5343267B2 (ja) | 2006-10-17 | 2007-10-17 | タラロゾール代謝物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8188124B2 (enExample) |
| EP (1) | EP2114895A4 (enExample) |
| JP (1) | JP5343267B2 (enExample) |
| KR (1) | KR101419965B1 (enExample) |
| CN (1) | CN101611016B (enExample) |
| AU (1) | AU2007311026B2 (enExample) |
| BR (1) | BRPI0718310A2 (enExample) |
| CA (1) | CA2667053C (enExample) |
| MX (1) | MX2009004096A (enExample) |
| WO (1) | WO2008049027A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9080145B2 (en) | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
| RU2473685C2 (ru) | 2007-07-31 | 2013-01-27 | Лайфскен, Инк. | Дифференцировка человеческих эмбриональных стволовых клеток |
| CN107574142B (zh) | 2007-11-27 | 2021-07-06 | 生命扫描有限公司 | 人胚胎干细胞的分化 |
| BRPI0908033A2 (pt) | 2008-02-21 | 2015-08-04 | Centocor Ortho Biotech Inc | Método placas de superfície modificada e composições para adesão, cultura e desprendimento de célula |
| CA2729121C (en) | 2008-06-30 | 2019-04-09 | Centocor Ortho Biotech Inc. | Differentiation of pluripotent stem cells |
| JP2012507289A (ja) | 2008-10-31 | 2012-03-29 | ヤンセン バイオテツク，インコーポレーテツド | ヒト胚性幹細胞の膵内分泌系への分化 |
| EP2346988B1 (en) | 2008-10-31 | 2017-05-31 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells to the pancreatic endocrine lineage |
| MX2011005288A (es) | 2008-11-20 | 2011-06-01 | Centocor Ortho Biotech Inc | Celulas madre pluripotentes en microportadores. |
| CA2744227C (en) | 2008-11-20 | 2018-10-02 | Centocor Ortho Biotech Inc. | Methods and compositions for cell attachment and cultivation on planar substrates |
| EP2456862A4 (en) | 2009-07-20 | 2013-02-27 | Janssen Biotech Inc | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS |
| DK2516625T3 (da) | 2009-12-23 | 2024-09-09 | Janssen Biotech Inc | Differentiering af humane embryonale stamceller |
| AU2011223900A1 (en) | 2010-03-01 | 2012-09-13 | Janssen Biotech, Inc. | Methods for purifying cells derived from pluripotent stem cells |
| AU2011250912A1 (en) | 2010-05-12 | 2012-11-22 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
| WO2012030540A2 (en) | 2010-08-31 | 2012-03-08 | Janssen Biotech, Inc. | Differentiation of pluripotent stem cells |
| CN103221536B (zh) | 2010-08-31 | 2016-08-31 | 詹森生物科技公司 | 人胚胎干细胞的分化 |
| KR101836850B1 (ko) | 2010-08-31 | 2018-03-09 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 분화 |
| US9248120B2 (en) | 2011-08-23 | 2016-02-02 | The Board Of Trustees Of The Leland Stanford Junior University | Reversing intestinal inflammation by inhibiting retinoic acid metabolism |
| RU2705001C2 (ru) | 2011-12-22 | 2019-11-01 | Янссен Байотек, Инк. | Дифференцировка эмбриональных стволовых клеток человека в одногормональные инсулинположительные клетки |
| MX354775B (es) | 2012-03-07 | 2018-03-20 | Janssen Biotech Inc | Medios definidos para la expansion y el mantenimiento de celulas madre pluripotentes. |
| CN104334719B (zh) | 2012-06-08 | 2018-02-13 | 詹森生物科技公司 | 人胚胎干细胞向胰腺内分泌细胞的分化 |
| MX2015008578A (es) | 2012-12-31 | 2015-09-07 | Janssen Biotech Inc | Diferenciacion de celulas madre embrionarias humanas en celulas endocrinas pancreaticas mediante el uso de relugadores de hb9. |
| DK2938722T3 (da) | 2012-12-31 | 2022-02-14 | Janssen Biotech Inc | Suspension og klyngedannelse af humane pluripotente celler til differentiering til endokrine pankreasceller |
| US10370644B2 (en) | 2012-12-31 | 2019-08-06 | Janssen Biotech, Inc. | Method for making human pluripotent suspension cultures and cells derived therefrom |
| KR102084561B1 (ko) | 2012-12-31 | 2020-03-04 | 얀센 바이오테크 인코포레이티드 | 췌장 내분비 세포로의 분화를 위한 공기-액체 계면에서의 인간 배아 줄기세포의 배양 |
| SG11201609473XA (en) | 2014-05-16 | 2016-12-29 | Janssen Biotech Inc | Use of small molecules to enhance mafa expression in pancreatic endocrine cells |
| WO2017180361A1 (en) | 2016-04-14 | 2017-10-19 | Janssen Biotech, Inc. | Differentiation of pluripotent stem cells to intestinal midgut endoderm cells |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3404749B2 (ja) | 1996-06-27 | 2003-05-12 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Ｎ―［４―（ヘテロアリールメチル）フェニル］―ヘテロアリールアミン |
| AP869A (en) | 1998-01-05 | 2000-09-04 | Pfizer | 2,3-Substituted indole compounds as anti-inflammatory and analgesic agents. |
| CN1596240A (zh) * | 2001-12-19 | 2005-03-16 | 阿特罗吉尼克斯公司 | 查耳酮衍生物及其治疗疾病的用途 |
| US20060205945A1 (en) * | 2004-05-14 | 2006-09-14 | Pfizer Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
| PL372356A1 (pl) * | 2005-01-20 | 2006-07-24 | ADAMED Sp.z o.o. | Nowe związki, pochodne kwasu 3-fenylopropionowego |
| TW200639163A (en) * | 2005-02-04 | 2006-11-16 | Genentech Inc | RAF inhibitor compounds and methods |
-
2007
- 2007-10-17 CN CN2007800387031A patent/CN101611016B/zh not_active Expired - Fee Related
- 2007-10-17 US US12/311,862 patent/US8188124B2/en not_active Expired - Fee Related
- 2007-10-17 WO PCT/US2007/081685 patent/WO2008049027A1/en not_active Ceased
- 2007-10-17 CA CA2667053A patent/CA2667053C/en not_active Expired - Fee Related
- 2007-10-17 BR BRPI0718310-0A patent/BRPI0718310A2/pt not_active IP Right Cessation
- 2007-10-17 JP JP2009533511A patent/JP5343267B2/ja not_active Expired - Fee Related
- 2007-10-17 AU AU2007311026A patent/AU2007311026B2/en not_active Ceased
- 2007-10-17 EP EP07854136A patent/EP2114895A4/en not_active Withdrawn
- 2007-10-17 MX MX2009004096A patent/MX2009004096A/es active IP Right Grant
- 2007-10-17 KR KR1020097009986A patent/KR101419965B1/ko not_active Expired - Fee Related
-
2012
- 2012-05-21 US US13/476,216 patent/US8399495B2/en not_active Expired - Fee Related
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