JP2010503629A5 - - Google Patents
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- Publication number
- JP2010503629A5 JP2010503629A5 JP2009527741A JP2009527741A JP2010503629A5 JP 2010503629 A5 JP2010503629 A5 JP 2010503629A5 JP 2009527741 A JP2009527741 A JP 2009527741A JP 2009527741 A JP2009527741 A JP 2009527741A JP 2010503629 A5 JP2010503629 A5 JP 2010503629A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- alkyl
- benzoxazol
- methyl
- piperazin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06120733.8 | 2006-09-15 | ||
| EP06120733A EP1900729A1 (en) | 2006-09-15 | 2006-09-15 | Benzoxazoles and oxazolopyridines being useful as Janus kinases inhibitors |
| PCT/EP2007/007983 WO2008031594A1 (en) | 2006-09-15 | 2007-09-13 | Benzoxazoles and oxazolopyridines being useful as janus kinases inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010503629A JP2010503629A (ja) | 2010-02-04 |
| JP2010503629A5 true JP2010503629A5 (https=) | 2010-10-28 |
| JP5325105B2 JP5325105B2 (ja) | 2013-10-23 |
Family
ID=37717673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009527741A Expired - Fee Related JP5325105B2 (ja) | 2006-09-15 | 2007-09-13 | ヤヌスキナーゼ阻害剤として有用なベンゾオキサゾールおよびオキサゾロピリジン |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US8629168B2 (https=) |
| EP (2) | EP1900729A1 (https=) |
| JP (1) | JP5325105B2 (https=) |
| KR (1) | KR20090064389A (https=) |
| CN (1) | CN101516860B (https=) |
| AR (1) | AR062786A1 (https=) |
| AT (1) | ATE532774T1 (https=) |
| AU (1) | AU2007296916B2 (https=) |
| BR (1) | BRPI0716841A2 (https=) |
| CA (1) | CA2660987A1 (https=) |
| CL (1) | CL2007002669A1 (https=) |
| CO (1) | CO6150142A2 (https=) |
| CR (1) | CR10639A (https=) |
| EA (1) | EA200900388A1 (https=) |
| ES (1) | ES2377148T3 (https=) |
| GT (1) | GT200900056A (https=) |
| IL (1) | IL196860A0 (https=) |
| MA (1) | MA30723B1 (https=) |
| MX (1) | MX2009002812A (https=) |
| NO (1) | NO20091469L (https=) |
| PA (1) | PA8748101A1 (https=) |
| PE (1) | PE20080842A1 (https=) |
| PL (1) | PL2066647T3 (https=) |
| PT (1) | PT2066647E (https=) |
| SM (1) | SMP200900023B (https=) |
| TN (1) | TN2009000070A1 (https=) |
| TW (1) | TW200819444A (https=) |
| UY (1) | UY30587A1 (https=) |
| WO (1) | WO2008031594A1 (https=) |
| ZA (1) | ZA200900477B (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2467670B (en) | 2007-10-04 | 2012-08-01 | Intellikine Inc | Chemical entities and therapeutic uses thereof |
| US8993580B2 (en) | 2008-03-14 | 2015-03-31 | Intellikine Llc | Benzothiazole kinase inhibitors and methods of use |
| JP5788316B2 (ja) | 2008-07-08 | 2015-09-30 | インテリカイン， エルエルシー | キナーゼインヒビターおよび使用方法 |
| EP2318415B1 (en) * | 2008-07-15 | 2013-02-20 | Sanofi | Oxazolopyrimidines as edg-1 receptor agonists |
| TW201010977A (en) * | 2008-08-12 | 2010-03-16 | Takeda Pharmaceutical | Amide compound |
| US8476431B2 (en) | 2008-11-03 | 2013-07-02 | Itellikine LLC | Benzoxazole kinase inhibitors and methods of use |
| WO2010061971A1 (ja) | 2008-11-28 | 2010-06-03 | 興和株式会社 | ピリジン－３－カルボキシアミド誘導体 |
| EP2518054A1 (en) | 2009-12-24 | 2012-10-31 | Takeda Pharmaceutical Company Limited | Amide compound |
| AR079980A1 (es) * | 2010-01-13 | 2012-03-07 | Sanofi Aventis | Derivados de oxazolopirimidina sustituida en 2,5,7 |
| US9295673B2 (en) | 2011-02-23 | 2016-03-29 | Intellikine Llc | Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof |
| US8907093B2 (en) * | 2011-07-07 | 2014-12-09 | Sanofi | Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring |
| US8580816B2 (en) * | 2011-07-07 | 2013-11-12 | Sanofi | Carboxylic acid derivatives having an oxazolo[5,4-b]pyridine ring |
| CN103102359B (zh) * | 2011-11-15 | 2016-11-09 | 江苏先声药业有限公司 | 嘧啶类化合物及其应用 |
| EP4556010A3 (en) | 2011-11-30 | 2025-07-23 | Emory University | Jak inhibitors for use in the prevention or treatment of a viral disease caused by a coronaviridae |
| WO2014075318A1 (zh) * | 2012-11-19 | 2014-05-22 | 江苏先声药业有限公司 | 嘧啶类化合物及其应用 |
| WO2014153509A1 (en) | 2013-03-22 | 2014-09-25 | Millennium Pharmaceuticals, Inc. | Combination of catalytic mtorc 1/2 inhibitors and selective inhibitors of aurora a kinase |
| CN103664759A (zh) * | 2013-12-06 | 2014-03-26 | 常熟市联创化学有限公司 | 一种3-羟基-2-硝基吡啶的制备方法 |
| WO2015117146A1 (en) | 2014-02-03 | 2015-08-06 | Quadriga Biosciences, Inc. | Beta-substituted gamma-amino acids and analogs as chemotherapeutic agents |
| ES2896882T3 (es) | 2014-02-03 | 2022-02-28 | Quadriga Biosciences Inc | Beta-aminoácidos beta sustituidos y análogos como agentes quimioterapéuticos |
| WO2016047678A1 (ja) * | 2014-09-25 | 2016-03-31 | 武田薬品工業株式会社 | 複素環化合物 |
| CN108026026B (zh) | 2015-08-03 | 2021-02-09 | 夸德里加生物科学公司 | 作为化疗剂的β-取代的β-氨基酸和类似物及其应用 |
| CN114761013A (zh) | 2019-09-27 | 2022-07-15 | 迪斯克医药公司 | 治疗骨髓纤维化和相关病症的方法 |
| WO2021231798A1 (en) | 2020-05-13 | 2021-11-18 | Disc Medicine, Inc. | Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis |
| TW202307005A (zh) | 2021-05-28 | 2023-02-16 | 美商邊際分析公司 | 以核醣體蛋白質S6激酶α-1 (RSK1)及核醣體蛋白質S6激酶α-3 (RSK2)之調節劑治療神經病症之方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1382339B1 (en) * | 1999-12-10 | 2007-12-05 | Pfizer Products Inc. | Compositions containing pyrrolo ¬2,3-d pyrimidine derivatives |
| SE0301373D0 (sv) * | 2003-05-09 | 2003-05-09 | Astrazeneca Ab | Novel compounds |
| DE10344223A1 (de) * | 2003-09-24 | 2005-04-21 | Merck Patent Gmbh | 1,3-Benzoxazolylderivate als Kinase-Inhibitoren |
| GB0402140D0 (en) * | 2004-01-30 | 2004-03-03 | Smithkline Beecham Corp | Novel compounds |
| EP1674467A1 (en) * | 2004-12-22 | 2006-06-28 | 4Sc Ag | 2,5- and 2,6-disubstituted benzazole derivatives useful as protein kinase inhibitors |
| ATE497959T1 (de) * | 2005-09-02 | 2011-02-15 | Hoffmann La Roche | Benzoxazol-, oxazolopyridin-, benzothiazol- und thiazolopyridinderivate |
| MX2009000769A (es) * | 2006-07-21 | 2009-01-28 | Novartis Ag | Compuestos de 2,4-di(arilaminio)-pirimidin-5-carboxamida como inhibidores de cinasas jak. |
-
2006
- 2006-09-15 EP EP06120733A patent/EP1900729A1/en not_active Ceased
-
2007
- 2007-09-12 UY UY30587A patent/UY30587A1/es not_active Application Discontinuation
- 2007-09-13 WO PCT/EP2007/007983 patent/WO2008031594A1/en not_active Ceased
- 2007-09-13 AU AU2007296916A patent/AU2007296916B2/en not_active Ceased
- 2007-09-13 PL PL07802300T patent/PL2066647T3/pl unknown
- 2007-09-13 PE PE2007001237A patent/PE20080842A1/es not_active Application Discontinuation
- 2007-09-13 KR KR1020097005248A patent/KR20090064389A/ko not_active Withdrawn
- 2007-09-13 ES ES07802300T patent/ES2377148T3/es active Active
- 2007-09-13 JP JP2009527741A patent/JP5325105B2/ja not_active Expired - Fee Related
- 2007-09-13 PT PT07802300T patent/PT2066647E/pt unknown
- 2007-09-13 CN CN2007800339907A patent/CN101516860B/zh not_active Expired - Fee Related
- 2007-09-13 EA EA200900388A patent/EA200900388A1/ru unknown
- 2007-09-13 AR ARP070104060A patent/AR062786A1/es unknown
- 2007-09-13 MX MX2009002812A patent/MX2009002812A/es active IP Right Grant
- 2007-09-13 CA CA002660987A patent/CA2660987A1/en not_active Abandoned
- 2007-09-13 BR BRPI0716841-1A2A patent/BRPI0716841A2/pt not_active IP Right Cessation
- 2007-09-13 AT AT07802300T patent/ATE532774T1/de active
- 2007-09-13 EP EP07802300A patent/EP2066647B1/en active Active
- 2007-09-13 US US12/440,298 patent/US8629168B2/en not_active Expired - Fee Related
- 2007-09-14 TW TW096134606A patent/TW200819444A/zh unknown
- 2007-09-14 CL CL200702669A patent/CL2007002669A1/es unknown
- 2007-09-14 PA PA20078748101A patent/PA8748101A1/es unknown
-
2009
- 2009-01-21 ZA ZA200900477A patent/ZA200900477B/xx unknown
- 2009-02-02 IL IL196860A patent/IL196860A0/en unknown
- 2009-02-26 CR CR10639A patent/CR10639A/es not_active Application Discontinuation
- 2009-02-27 TN TN2009000070A patent/TN2009000070A1/fr unknown
- 2009-03-10 CO CO09024347A patent/CO6150142A2/es unknown
- 2009-03-11 GT GT200900056A patent/GT200900056A/es unknown
- 2009-03-30 MA MA31738A patent/MA30723B1/fr unknown
- 2009-04-09 SM SM200900023T patent/SMP200900023B/it unknown
- 2009-04-15 NO NO20091469A patent/NO20091469L/no not_active Application Discontinuation
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