|
EP2409753B1
(en)
*
|
2005-07-28 |
2017-07-19 |
Carbon Sink Inc. |
Removal of carbon dioxide from air
|
|
WO2007073486A2
(en)
|
2005-12-20 |
2007-06-28 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
|
US8841255B2
(en)
*
|
2005-12-20 |
2014-09-23 |
Duke University |
Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
|
|
US20130172274A1
(en)
|
2005-12-20 |
2013-07-04 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
|
US7709227B2
(en)
|
2006-01-04 |
2010-05-04 |
Phasebio Pharmaceuticals, Inc. |
Multimeric ELP fusion constructs
|
|
EP2327768B1
(en)
|
2006-04-03 |
2015-09-09 |
Promega Corporation |
Permuted and nonpermuted luciferase biosensors
|
|
WO2009142735A2
(en)
|
2008-05-19 |
2009-11-26 |
Promega Corporation |
LUCIFERASE BIOSENSORS FOR cAMP
|
|
CN102131516B
(zh)
|
2008-06-27 |
2016-03-16 |
杜克大学 |
包含弹性蛋白样肽的治疗剂
|
|
US20110229877A1
(en)
|
2008-07-07 |
2011-09-22 |
Oxford Nanopore Technologies Limited |
Enzyme-pore constructs
|
|
EP2310534B1
(en)
|
2008-07-07 |
2018-09-05 |
Oxford Nanopore Technologies Limited |
Base-detecting pore
|
|
GB0820927D0
(en)
|
2008-11-14 |
2008-12-24 |
Isis Innovation |
Method
|
|
CN101418290A
(zh)
*
|
2008-12-02 |
2009-04-29 |
中山大学 |
一种高效的elp融合蛋白酶及其制备和应用
|
|
WO2010085768A1
(en)
|
2009-01-26 |
2010-07-29 |
Nanoink,Inc. |
Large area, homogeneous array fabbrication including leveling with use of bright spots
|
|
EP2391732B1
(en)
|
2009-01-30 |
2015-05-27 |
Oxford Nanopore Technologies Limited |
Methods using adaptors for nucleic acid constructs in transmembrane sequencing
|
|
KR20110125226A
(ko)
*
|
2009-01-30 |
2011-11-18 |
옥스포드 나노포어 테크놀로지즈 리미티드 |
혼성화 링커
|
|
GB0905140D0
(en)
|
2009-03-25 |
2009-05-06 |
Isis Innovation |
Method
|
|
WO2010124180A1
(en)
*
|
2009-04-23 |
2010-10-28 |
Phasebio Pharmaceuticals, Inc. |
Phenylalanine hydroxylase fusion protein and methods for treating phenylketonuria
|
|
US9029505B2
(en)
|
2009-08-14 |
2015-05-12 |
Phasebio Pharmaceuticals, Inc. |
Modified vasoactive intestinal peptides
|
|
US8940868B2
(en)
*
|
2009-10-08 |
2015-01-27 |
The General Hospital Corporation |
Elastin based growth factor delivery platform for wound healing and regeneration
|
|
WO2011112549A2
(en)
*
|
2010-03-10 |
2011-09-15 |
Emory University |
Temperature sensitive conjugate compositions, and uses related thereto
|
|
US9290794B2
(en)
|
2010-05-11 |
2016-03-22 |
Promega Corporation |
Mutant protease biosensors with enhanced detection characteristics
|
|
US8735559B2
(en)
|
2010-05-11 |
2014-05-27 |
Promega Corporation |
Mutant protease biosensors with enhanced detection characteristics
|
|
CN101955960B
(zh)
*
|
2010-08-03 |
2012-05-23 |
中山大学 |
一种利用类弹性蛋白标签纯化重组乳糖酶的方法
|
|
KR101939420B1
(ko)
|
2011-02-11 |
2019-01-16 |
옥스포드 나노포어 테크놀로지즈 리미티드 |
돌연변이체 세공
|
|
EP2673297A2
(en)
|
2011-02-11 |
2013-12-18 |
Zyngenia, Inc. |
Monovalent and multivalent multispecific complexes and uses thereof
|
|
CA2873553C
(en)
|
2011-06-06 |
2020-01-28 |
Phasebio Pharmaceuticals, Inc. |
Use of modified vasoactive intestinal peptides in the treatment of hypertension
|
|
CN102241747A
(zh)
*
|
2011-06-17 |
2011-11-16 |
李立文 |
类人弹性蛋白及其生产方法
|
|
JP6298404B2
(ja)
|
2011-07-25 |
2018-03-20 |
オックスフォード ナノポール テクノロジーズ リミテッド |
膜貫通ポアを用いる二重鎖ポリヌクレオチド配列決定のためのヘアピンループ方法
|
|
WO2013016578A2
(en)
*
|
2011-07-26 |
2013-01-31 |
University Of Southern California |
Controlled release of ocular biopharmaceuticals using bioresponsive protein polymers
|
|
CN104023784B
(zh)
*
|
2011-08-24 |
2018-05-25 |
费斯生物制药公司 |
供持续释放的活性剂制剂
|
|
WO2013120022A2
(en)
*
|
2012-02-08 |
2013-08-15 |
Seneb Biosciences, Inc. |
Treatment of hypoglycemia
|
|
US20130210747A1
(en)
|
2012-02-13 |
2013-08-15 |
University Of Southern California |
Methods and Therapeutics Comprising Ligand-Targeted ELPs
|
|
JP6157877B2
(ja)
*
|
2012-02-28 |
2017-07-05 |
三洋化成工業株式会社 |
組織再生用ゲル、組織再生用タンパク質溶液及び組織再生用ゲルの製造方法
|
|
KR102083695B1
(ko)
|
2012-04-10 |
2020-03-02 |
옥스포드 나노포어 테크놀로지즈 리미티드 |
돌연변이체 리세닌 기공
|
|
US11155860B2
(en)
|
2012-07-19 |
2021-10-26 |
Oxford Nanopore Technologies Ltd. |
SSB method
|
|
WO2014026054A2
(en)
|
2012-08-10 |
2014-02-13 |
University Of Southern California |
CD20 scFv-ELPs METHODS AND THERAPEUTICS
|
|
WO2014028776A1
(en)
*
|
2012-08-15 |
2014-02-20 |
Zyngenia, Inc. |
Monovalent and multivalent multispecific complexes and uses thereof
|
|
JP2016505627A
(ja)
*
|
2013-01-15 |
2016-02-25 |
フェーズバイオ ファーマシューティカルズ，インコーポレイテッド |
治療剤、組成物、および血糖コントロールのための方法
|
|
GB201314695D0
(en)
|
2013-08-16 |
2013-10-02 |
Oxford Nanopore Tech Ltd |
Method
|
|
CA2901545C
(en)
|
2013-03-08 |
2019-10-08 |
Oxford Nanopore Technologies Limited |
Use of spacer elements in a nucleic acid to control movement of a helicase
|
|
GB201313477D0
(en)
|
2013-07-29 |
2013-09-11 |
Univ Leuven Kath |
Nanopore biosensors for detection of proteins and nucleic acids
|
|
EP3785725A1
(en)
*
|
2013-10-01 |
2021-03-03 |
University of Mississippi Medical Center |
Composition and method for therapeutic agent delivery during pregnancy
|
|
US11268127B2
(en)
|
2014-02-04 |
2022-03-08 |
Duke University |
Systems and devices for protease detection based on engineered polymers and biopolymers and methods of use
|
|
GB201403096D0
(en)
|
2014-02-21 |
2014-04-09 |
Oxford Nanopore Tech Ltd |
Sample preparation method
|
|
PL3145530T3
(pl)
|
2014-04-21 |
2021-10-18 |
D&D Pharmatech Inc. |
Agonisty receptora trail w leczeniu chorób zwłóknieniowych
|
|
EP3137490B1
(en)
|
2014-05-02 |
2021-01-27 |
Oxford Nanopore Technologies Limited |
Mutant pores
|
|
US11052132B2
(en)
|
2014-05-08 |
2021-07-06 |
Phasebio Pharmaceuticals, Inc. |
Methods and compositions for treating cystic fibrosis
|
|
CA2959220A1
(en)
|
2014-09-01 |
2016-03-10 |
Vib Vzw |
Mutant csgg pores
|
|
EP3204511B1
(en)
|
2014-10-07 |
2021-07-28 |
Oxford Nanopore Technologies Limited |
Mutant pores
|
|
GB201418159D0
(en)
|
2014-10-14 |
2014-11-26 |
Oxford Nanopore Tech Ltd |
Method
|
|
EP3220936A4
(en)
*
|
2014-11-21 |
2018-08-22 |
Phasebio Pharmaceuticals, Inc. |
Elp fusion proteins for controlled and sustained release
|
|
CA2970478A1
(en)
|
2014-12-10 |
2016-06-16 |
S-Aima Holding Company, Llc |
Generation of hemoglobin-based oxygen carriers using elastin-like polypeptides
|
|
CN114652817B
(zh)
|
2015-02-09 |
2026-04-17 |
费斯生物制药公司 |
用于治疗肌肉疾病和病症的方法和组合物
|
|
WO2017020025A1
(en)
*
|
2015-07-29 |
2017-02-02 |
Kiick Kristi |
Thermoresponsive bioconjugates and their controlled delivery of cargo
|
|
CN106632682A
(zh)
*
|
2015-08-04 |
2017-05-10 |
清华大学 |
融合蛋白ifn-elp及其应用
|
|
EA037478B1
(ru)
|
2015-08-04 |
2021-04-01 |
Дьюк Юниверсити |
Генетически кодируемые внутренне неупорядоченные полимеры-"невидимки" для доставки и способы их применения
|
|
KR101759122B1
(ko)
|
2015-08-07 |
2017-07-18 |
계명대학교 산학협력단 |
오렉신 a를 함유하는 당뇨병 치료용 약학 조성물
|
|
US11007251B2
(en)
|
2015-12-17 |
2021-05-18 |
The Johns Hopkins University |
Ameliorating systemic sclerosis with death receptor agonists
|
|
US11752213B2
(en)
|
2015-12-21 |
2023-09-12 |
Duke University |
Surfaces having reduced non-specific binding and antigenicity
|
|
US11059870B2
(en)
|
2016-03-14 |
2021-07-13 |
Industry-University Cooperation Foundation Hanyang University Erica Campus |
Polypeptides with phase transition, triblock polypeptides of the polypeptide-calmodulin-polypeptide with multi-stimuli responsiveness, hydrogel of the triblock polypeptides, and its uses
|
|
KR102028931B1
(ko)
*
|
2016-03-24 |
2019-10-08 |
한양대학교 에리카산학협력단 |
지능형 약물 전달을 위한 다중 자극 반응성을 지닌 칼모듈린-엘라스틴 이중 블럭 폴리펩타이드의 동적 나노 전달체 및 제조방법
|
|
EA201892260A1
(ru)
|
2016-04-07 |
2019-03-29 |
Дзе Джонс Хопкинс Юниверсити |
Композиции и способы для лечения панкреатита и боли с применением агонистов рецептора смерти
|
|
MX2018013546A
(es)
*
|
2016-05-06 |
2019-04-22 |
Phasebio Pharmaceuticals Inc |
Proteinas de fusion de elp para liberacion controlada y sostenida.
|
|
GB201609220D0
(en)
|
2016-05-25 |
2016-07-06 |
Oxford Nanopore Tech Ltd |
Method
|
|
WO2017210476A1
(en)
|
2016-06-01 |
2017-12-07 |
Duke University |
Nonfouling biosensors
|
|
CN107459580A
(zh)
*
|
2016-06-06 |
2017-12-12 |
易金阳 |
一种利用酵母菌表达含有穿膜肽的寡肽‑1（egf）创新制备工艺
|
|
WO2018053201A1
(en)
|
2016-09-14 |
2018-03-22 |
Duke University |
Triblock polypeptide-based nanoparticles for the delivery of hydrophilic drugs
|
|
JP2020500150A
(ja)
|
2016-09-23 |
2020-01-09 |
デューク ユニバーシティ |
下限臨界溶液温度挙動を有する非反復かつ非構造的ポリペプチド
|
|
CN106519040B
(zh)
*
|
2016-11-02 |
2020-03-27 |
南京大学 |
一种含肿瘤坏死因子相关凋亡诱导配体的融合蛋白和其制备方法及由该蛋白自组装的纳米粒
|
|
WO2018132732A1
(en)
|
2017-01-12 |
2018-07-19 |
Duke University |
Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly
|
|
WO2018213320A1
(en)
|
2017-05-15 |
2018-11-22 |
Duke University |
Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents
|
|
KR101955366B1
(ko)
*
|
2017-06-02 |
2019-03-07 |
인제대학교 산학협력단 |
인터페론 베타-엘라스틴 재조합 단백질 및 이의 생산방법
|
|
WO2019006374A1
(en)
|
2017-06-30 |
2019-01-03 |
Duke University |
ORDER AND DISORDER AS A DESIGN PRINCIPLE FOR STIMULI-SENSITIVE BIOPOLYMER NETWORKS
|
|
JP7074995B2
(ja)
*
|
2017-10-13 |
2022-05-25 |
林兼産業株式会社 |
線維芽細胞増殖促進剤及び線維芽細胞におけるエラスチン産生促進剤
|
|
WO2019147954A1
(en)
|
2018-01-26 |
2019-08-01 |
Duke University |
Albumin binding peptide-drug (aibiped) conjugates and methods of making and using same
|
|
CN108531492A
(zh)
*
|
2018-04-23 |
2018-09-14 |
内蒙古农业大学 |
利用类弹性蛋白elp构建活性绵羊β-防御素sbd-1体外表达的方法
|
|
EP3788343B1
(en)
|
2018-04-30 |
2024-03-27 |
Duke University |
Stimuli-responsive peg-like polymer-based drug delivery platform
|
|
GB201807793D0
(en)
|
2018-05-14 |
2018-06-27 |
Oxford Nanopore Tech Ltd |
Method
|
|
US11649275B2
(en)
|
2018-08-02 |
2023-05-16 |
Duke University |
Dual agonist fusion proteins
|
|
US12269847B2
(en)
|
2018-08-16 |
2025-04-08 |
Donaldson Company, Inc. |
Genetically encoded polypeptide for affinity capture and purification of biologics
|
|
US12594347B2
(en)
|
2018-09-07 |
2026-04-07 |
Duke University |
Nanoparticulate drug delivery systems
|
|
US11512314B2
(en)
|
2019-07-12 |
2022-11-29 |
Duke University |
Amphiphilic polynucleotides
|
|
EP4010008A4
(en)
*
|
2019-08-09 |
2023-08-16 |
Phasebio Pharmaceuticals, Inc. |
ELP FUSION PROTEINS INCLUDING PARATHYROID HORMONE FOR CONTROLLED AND SUSTAINED RELEASE
|
|
US20230099707A1
(en)
*
|
2020-02-19 |
2023-03-30 |
Isolere Bio, Inc. |
Protein-based purification matrices and methods of using the same
|
|
WO2021202546A1
(en)
|
2020-03-31 |
2021-10-07 |
Cyclerion Therapeutics, Inc. |
Early drug interventions to reduce covid-19 related respiratory distress, need for ventilator assistance and death
|
|
US11767353B2
(en)
|
2020-06-05 |
2023-09-26 |
Theraly Fibrosis, Inc. |
Trail compositions with reduced immunogenicity
|
|
KR102687389B1
(ko)
*
|
2020-08-25 |
2024-07-25 |
한양대학교 에리카산학협력단 |
자극 반응성 및 표면 부착성을 가진 점착성 엘라스틴 및 서커린 기반 다중 블록 코폴리펩타이드, 그의 자가조립 구조체 및 주사형 하이드로겔의 생접착제 응용
|
|
AU2021410080A1
(en)
|
2020-12-23 |
2023-06-22 |
Jazz Pharmaceuticals Ireland Ltd. |
Methods of purifying charge-shielded fusion proteins
|
|
US20240317837A1
(en)
*
|
2021-02-19 |
2024-09-26 |
Isolere Bio, Inc. |
Fusion proteins comprising a protein with phase behavior
|
|
WO2023225802A1
(zh)
*
|
2022-05-23 |
2023-11-30 |
复旦大学 |
三叶因子2/干扰素α2融合蛋白及其防治病毒感染性疾病的应用
|
|
CN115724915B
(zh)
*
|
2022-08-17 |
2025-08-12 |
上普博源（北京）生物科技有限公司 |
类弹性蛋白多肽粘合剂及其制备方法与应用
|
|
CN117777303A
(zh)
*
|
2022-09-27 |
2024-03-29 |
北京大学 |
一种高亲和力pd1蛋白偶联物及其应用
|
|
JP2025541413A
(ja)
*
|
2022-12-27 |
2025-12-18 |
ネクスセラ カンパニー リミテッド |
エラスチン類似ポリペプチド基盤の組換えタンパク質の作製及びその動物細胞発現プラットフォーム
|
|
WO2025076213A1
(en)
*
|
2023-10-04 |
2025-04-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
Isothermally phase-separable elastin-like polypeptides, compositions, and methods of use thereof
|
|
WO2025100511A1
(ja)
*
|
2023-11-10 |
2025-05-15 |
地方独立行政法人神奈川県立産業技術総合研究所 |
融合ペプチド
|
|
WO2026005476A1
(ko)
*
|
2024-06-26 |
2026-01-02 |
주식회사 넥스세라 |
혈소판 감소증 치료를 위한 재조합 단백질 및 이의 용도
|