JP2010502713A5 - - Google Patents
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- JP2010502713A5 JP2010502713A5 JP2009527422A JP2009527422A JP2010502713A5 JP 2010502713 A5 JP2010502713 A5 JP 2010502713A5 JP 2009527422 A JP2009527422 A JP 2009527422A JP 2009527422 A JP2009527422 A JP 2009527422A JP 2010502713 A5 JP2010502713 A5 JP 2010502713A5
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- 239000002245 particle Substances 0.000 claims description 146
- 239000000203 mixture Substances 0.000 claims description 38
- 210000003097 mucus Anatomy 0.000 claims description 30
- 239000012867 bioactive agent Substances 0.000 claims description 20
- 241000700605 Viruses Species 0.000 claims description 18
- 239000008194 pharmaceutical composition Substances 0.000 claims description 6
- 239000002872 contrast media Substances 0.000 claims description 5
- 229920000642 polymer Polymers 0.000 claims description 5
- 229920001577 copolymer Polymers 0.000 claims description 4
- 239000003814 drug Substances 0.000 claims description 4
- 210000004400 mucous membrane Anatomy 0.000 claims description 4
- 239000004094 surface-active agent Substances 0.000 claims description 4
- 229940124597 therapeutic agent Drugs 0.000 claims description 4
- 210000001519 tissue Anatomy 0.000 claims description 4
- 239000003937 drug carrier Substances 0.000 claims description 2
- 108010003272 Hyaluronate lyase Proteins 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical group CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims 1
- 229920001400 block copolymer Polymers 0.000 claims 1
- 125000006353 oxyethylene group Chemical group 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 15
- 238000000034 method Methods 0.000 description 15
- 238000012986 modification Methods 0.000 description 14
- 230000004048 modification Effects 0.000 description 14
- 108020004707 nucleic acids Proteins 0.000 description 7
- 102000039446 nucleic acids Human genes 0.000 description 7
- 150000007523 nucleic acids Chemical class 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- 239000004793 Polystyrene Substances 0.000 description 6
- 239000000825 pharmaceutical preparation Substances 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 238000006073 displacement reaction Methods 0.000 description 5
- 238000009792 diffusion process Methods 0.000 description 4
- 239000002202 Polyethylene glycol Substances 0.000 description 3
- 150000001720 carbohydrates Chemical class 0.000 description 3
- 235000014633 carbohydrates Nutrition 0.000 description 3
- 239000000032 diagnostic agent Substances 0.000 description 3
- 229940039227 diagnostic agent Drugs 0.000 description 3
- 150000002632 lipids Chemical class 0.000 description 3
- 239000000816 peptidomimetic Substances 0.000 description 3
- 229920001223 polyethylene glycol Polymers 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 150000003384 small molecules Chemical class 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 2
- 108090001008 Avidin Proteins 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000001415 gene therapy Methods 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910044991 metal oxide Inorganic materials 0.000 description 1
- 150000004706 metal oxides Chemical class 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 239000002096 quantum dot Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84328206P | 2006-09-08 | 2006-09-08 | |
| PCT/US2007/019522 WO2008030557A2 (en) | 2006-09-08 | 2007-09-07 | Compositions and methods for enhancing transport through mucus |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013110583A Division JP2013163697A (ja) | 2006-09-08 | 2013-05-27 | 粘液を通る輸送を増強するための組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010502713A JP2010502713A (ja) | 2010-01-28 |
| JP2010502713A5 true JP2010502713A5 (https=) | 2011-10-27 |
Family
ID=38945776
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009527422A Withdrawn JP2010502713A (ja) | 2006-09-08 | 2007-09-07 | 粘液を通る輸送を増強するための組成物および方法 |
| JP2013110583A Withdrawn JP2013163697A (ja) | 2006-09-08 | 2013-05-27 | 粘液を通る輸送を増強するための組成物および方法 |
| JP2014256264A Active JP6297481B2 (ja) | 2006-09-08 | 2014-12-18 | 粘液を通る輸送を増強するための組成物および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013110583A Withdrawn JP2013163697A (ja) | 2006-09-08 | 2013-05-27 | 粘液を通る輸送を増強するための組成物および方法 |
| JP2014256264A Active JP6297481B2 (ja) | 2006-09-08 | 2014-12-18 | 粘液を通る輸送を増強するための組成物および方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (6) | US20100215580A1 (https=) |
| EP (1) | EP2061433B1 (https=) |
| JP (3) | JP2010502713A (https=) |
| AT (1) | ATE498393T1 (https=) |
| AU (1) | AU2007292902B8 (https=) |
| CA (1) | CA2663003C (https=) |
| DE (1) | DE602007012559D1 (https=) |
| ES (1) | ES2360538T3 (https=) |
| WO (1) | WO2008030557A2 (https=) |
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| EP2538929A4 (en) | 2010-02-25 | 2014-07-09 | Univ Johns Hopkins | DELAYED RELEASE OF THERAPIES IN A PART OF THE EYE |
| EP2563455A4 (en) | 2010-04-28 | 2014-02-19 | Kimberly Clark Co | METHOD FOR INCREASING THE PERMEABILITY OF AN EPITHELIAL BARRIER |
| CA2797204C (en) | 2010-04-28 | 2018-06-12 | Kimberly-Clark Worldwide, Inc. | Device for delivery of rheumatoid arthritis medication |
| JP5860033B2 (ja) | 2010-04-28 | 2016-02-16 | キンバリー クラーク ワールドワイド インコーポレイテッド | ｓｉＲＮＡ送達用の医療デバイス |
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-
2007
- 2007-09-07 DE DE602007012559T patent/DE602007012559D1/de active Active
- 2007-09-07 WO PCT/US2007/019522 patent/WO2008030557A2/en not_active Ceased
- 2007-09-07 AT AT07837876T patent/ATE498393T1/de not_active IP Right Cessation
- 2007-09-07 EP EP07837876A patent/EP2061433B1/en not_active Revoked
- 2007-09-07 JP JP2009527422A patent/JP2010502713A/ja not_active Withdrawn
- 2007-09-07 ES ES07837876T patent/ES2360538T3/es active Active
- 2007-09-07 CA CA2663003A patent/CA2663003C/en active Active
- 2007-09-07 US US12/310,751 patent/US20100215580A1/en not_active Abandoned
- 2007-09-07 AU AU2007292902A patent/AU2007292902B8/en active Active
-
2012
- 2012-12-03 US US13/692,442 patent/US20130164343A1/en not_active Abandoned
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2013
- 2013-05-27 JP JP2013110583A patent/JP2013163697A/ja not_active Withdrawn
-
2014
- 2014-12-18 JP JP2014256264A patent/JP6297481B2/ja active Active
-
2016
- 2016-06-29 US US15/196,178 patent/US20170095566A1/en not_active Abandoned
-
2018
- 2018-05-17 US US15/982,447 patent/US20180264135A1/en not_active Abandoned
-
2020
- 2020-07-22 US US16/936,220 patent/US20200345864A1/en not_active Abandoned
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2022
- 2022-08-05 US US17/882,132 patent/US20230108636A1/en not_active Abandoned
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