JP2010500375A - 活性剤の多段階送達 - Google Patents

活性剤の多段階送達 Download PDF

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Publication number
JP2010500375A
JP2010500375A JP2009523983A JP2009523983A JP2010500375A JP 2010500375 A JP2010500375 A JP 2010500375A JP 2009523983 A JP2009523983 A JP 2009523983A JP 2009523983 A JP2009523983 A JP 2009523983A JP 2010500375 A JP2010500375 A JP 2010500375A
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stage
particles
particle
composition
stage particle
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JP2009523983A
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Japanese (ja)
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JP2010500375A5 (https=
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フェラーリ，マウロ
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University of Texas System
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University of Texas System
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Publication of JP2010500375A publication Critical patent/JP2010500375A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009523983A 2006-08-08 2007-08-08 活性剤の多段階送達 Pending JP2010500375A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82175006P 2006-08-08 2006-08-08
US91434807P 2007-04-27 2007-04-27
PCT/US2007/075516 WO2008021908A2 (en) 2006-08-08 2007-08-08 Multistage delivery of active agents

Publications (2)

Publication Number Publication Date
JP2010500375A true JP2010500375A (ja) 2010-01-07
JP2010500375A5 JP2010500375A5 (https=) 2010-09-24

Family

ID=39082940

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009523983A Pending JP2010500375A (ja) 2006-08-08 2007-08-08 活性剤の多段階送達

Country Status (8)

Country Link
US (4) US20080311182A1 (https=)
EP (1) EP2056794A4 (https=)
JP (1) JP2010500375A (https=)
CN (1) CN101652126B (https=)
AU (1) AU2007286203B2 (https=)
CA (1) CA2664919A1 (https=)
MX (1) MX2009001461A (https=)
WO (1) WO2008021908A2 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013537540A (ja) * 2010-08-16 2013-10-03 オーストラリアン ニュークリア サイエンス アンド テクノロジー オーガニゼーション 生体分子を送達するためのセラミック粒子を含む粒子状物質
JP2015536319A (ja) * 2012-10-16 2015-12-21 ウィリアム・マーシュ・ライス・ユニバーシティ 薬剤耐性を克服するための改善されたナノベクターベースの薬物送達システム
JP2018519347A (ja) * 2015-07-09 2018-07-19 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 融合性リポソーム被覆多孔質ケイ素ナノ粒子
JP2019510085A (ja) * 2016-03-08 2019-04-11 ロス ガトス ファーマスーティカルズ， インク．Ｌｏｓ Ｇａｔｏｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 癌治療のためのナノ粒子ならびに方法および化合物
JP2020504177A (ja) * 2017-01-04 2020-02-06 ナノティックス，エルエルシー 捕捉粒子をアセンブルするための方法

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US7854944B2 (en) * 2004-12-17 2010-12-21 Advanced Cardiovascular Systems, Inc. Tissue regeneration
CA2648581A1 (en) 2006-04-07 2008-09-12 Chimeros, Inc. Compositions and methods for treating b- cell malignancies
US8563022B2 (en) * 2006-10-11 2013-10-22 Board Of Regents Of The University Of Texas System Particles for cell targeting
US8361508B2 (en) * 2007-02-26 2013-01-29 Board Of Regents Of The University Of Texas System Endocytotic particles
US8920625B2 (en) 2007-04-27 2014-12-30 Board Of Regents Of The University Of Texas System Electrochemical method of making porous particles using a constant current density
EP2288336B8 (en) * 2008-04-25 2017-03-22 Northwestern University Nanostructures suitable for sequestering cholesterol
EP2326314A1 (en) * 2008-07-29 2011-06-01 Board of Regents of the University of Texas System Particle compositions with a pre-selected cell internalization mode
US8173115B2 (en) 2008-07-29 2012-05-08 The Board Of Regents Of The University Of Texas System Particle compositions with a pre-selected cell internalization mode
WO2010025322A2 (en) * 2008-08-28 2010-03-04 The Florida International University Board Of Trustees Magnetic nanodelivery of therapeutic agents across the blood brain barrier
KR20110103442A (ko) * 2008-12-23 2011-09-20 보드 오브 리전츠 더 유니버시티 오브 텍사스 시스템 염증 표적화 입자
US20100233270A1 (en) 2009-01-08 2010-09-16 Northwestern University Delivery of Oligonucleotide-Functionalized Nanoparticles
MX2011007532A (es) * 2009-01-15 2011-11-04 Univ Texas Estructuras porosas con cinetica de biodegradacion modificada.
JP5960434B2 (ja) * 2009-02-18 2016-08-02 アラダイム コーポレーション 肺送達のためのｐＨ調節された製剤
US8808733B2 (en) 2009-03-31 2014-08-19 The Board Of Trustees Of The University Of Arkansas Method of controlled drug release from a liposome carrier
WO2010120874A2 (en) 2009-04-14 2010-10-21 Chimeros, Inc. Chimeric therapeutics, compositions, and methods for using same
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WO2011105520A1 (ja) * 2010-02-26 2011-09-01 国立大学法人 長崎大学 抗原または薬物送達複合体
CN103081107B (zh) 2010-03-09 2017-02-08 得克萨斯州大学系统董事会 多孔和非多孔纳米结构
EP2547370A4 (en) * 2010-03-17 2014-06-25 Univ Texas UNIVERSAL CELL-ORIENTED THEROSTICISM
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CN103608285B (zh) * 2011-04-14 2016-07-06 加利福尼亚大学董事会 多功能纳米颗粒设计和应用
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US9101547B2 (en) 2011-08-04 2015-08-11 Nano And Advanced Materials Institute Limited Enteric-coated capsule containing cationic nanoparticles for oral insulin delivery
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US9849087B2 (en) 2011-11-08 2017-12-26 The Board Of Trustees Of The University Of Arkansas Methods and compositions for X-ray induced release from pH sensitive liposomes
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US10842749B2 (en) * 2012-06-12 2020-11-24 The Methodist Hospital Research Institute Compositions and methods of treating therapy resistant cancer and uses thereof
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JP2015007209A (ja) * 2013-05-31 2015-01-15 株式会社リコー コアシェル型粒子、及びその製造方法
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US10568898B2 (en) 2013-08-13 2020-02-25 Northwestern University Lipophilic nanoparticles for drug delivery
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CN111132666B (zh) * 2017-07-25 2022-11-04 雷莫内克斯生物制药有限公司 用于将生理活性成分递送至血管的组合物
KR102152348B1 (ko) 2017-09-05 2020-09-08 주식회사 레모넥스 세포 운명 조절용 조성물
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JPH10203964A (ja) * 1997-01-16 1998-08-04 Lipotec Sa 難吸収性薬剤の経口生物学的利用能を改善する新しい調剤
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013537540A (ja) * 2010-08-16 2013-10-03 オーストラリアン ニュークリア サイエンス アンド テクノロジー オーガニゼーション 生体分子を送達するためのセラミック粒子を含む粒子状物質
JP2015536319A (ja) * 2012-10-16 2015-12-21 ウィリアム・マーシュ・ライス・ユニバーシティ 薬剤耐性を克服するための改善されたナノベクターベースの薬物送達システム
JP2018519347A (ja) * 2015-07-09 2018-07-19 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 融合性リポソーム被覆多孔質ケイ素ナノ粒子
JP2019510085A (ja) * 2016-03-08 2019-04-11 ロス ガトス ファーマスーティカルズ， インク．Ｌｏｓ Ｇａｔｏｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 癌治療のためのナノ粒子ならびに方法および化合物
JP2020504177A (ja) * 2017-01-04 2020-02-06 ナノティックス，エルエルシー 捕捉粒子をアセンブルするための方法
JP2023075293A (ja) * 2017-01-04 2023-05-30 ナノティックス，エルエルシー 捕捉粒子をアセンブルするための方法

Also Published As

Publication number Publication date
HK1140139A1 (zh) 2010-10-08
US20080311182A1 (en) 2008-12-18
AU2007286203B2 (en) 2013-05-02
MX2009001461A (es) 2009-07-02
WO2008021908A2 (en) 2008-02-21
US20190111000A1 (en) 2019-04-18
AU2007286203A2 (en) 2009-03-19
US10143658B2 (en) 2018-12-04
EP2056794A2 (en) 2009-05-13
WO2008021908A3 (en) 2008-08-14
US20160051481A1 (en) 2016-02-25
CN101652126B (zh) 2013-07-17
AU2007286203A1 (en) 2008-02-21
CA2664919A1 (en) 2008-02-21
US20210338593A1 (en) 2021-11-04
CN101652126A (zh) 2010-02-17
EP2056794A4 (en) 2012-12-26

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