CN101652126B - 活性试剂的多级递送 - Google Patents

活性试剂的多级递送 Download PDF

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Publication number
CN101652126B
CN101652126B CN2007800374243A CN200780037424A CN101652126B CN 101652126 B CN101652126 B CN 101652126B CN 2007800374243 A CN2007800374243 A CN 2007800374243A CN 200780037424 A CN200780037424 A CN 200780037424A CN 101652126 B CN101652126 B CN 101652126B
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particles
particle
composition
primary particle
silicon
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Chinese (zh)
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CN101652126A (zh
Inventor
M·菲拉里
E·塔斯齐奥提
J·萨卡莫托
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University of Texas System
Ohio State University Research Foundation
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Ohio State University Research Foundation
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2007800374243A 2006-08-08 2007-08-08 活性试剂的多级递送 Active CN101652126B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US82175006P 2006-08-08 2006-08-08
US60/821,750 2006-08-08
US91434807P 2007-04-27 2007-04-27
US60/914,348 2007-04-27
PCT/US2007/075516 WO2008021908A2 (en) 2006-08-08 2007-08-08 Multistage delivery of active agents

Publications (2)

Publication Number Publication Date
CN101652126A CN101652126A (zh) 2010-02-17
CN101652126B true CN101652126B (zh) 2013-07-17

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CN2007800374243A Active CN101652126B (zh) 2006-08-08 2007-08-08 活性试剂的多级递送

Country Status (8)

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US (4) US20080311182A1 (https=)
EP (1) EP2056794A4 (https=)
JP (1) JP2010500375A (https=)
CN (1) CN101652126B (https=)
AU (1) AU2007286203B2 (https=)
CA (1) CA2664919A1 (https=)
MX (1) MX2009001461A (https=)
WO (1) WO2008021908A2 (https=)

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Also Published As

Publication number Publication date
US20080311182A1 (en) 2008-12-18
CN101652126A (zh) 2010-02-17
EP2056794A2 (en) 2009-05-13
AU2007286203B2 (en) 2013-05-02
WO2008021908A2 (en) 2008-02-21
CA2664919A1 (en) 2008-02-21
US20160051481A1 (en) 2016-02-25
MX2009001461A (es) 2009-07-02
AU2007286203A1 (en) 2008-02-21
EP2056794A4 (en) 2012-12-26
AU2007286203A2 (en) 2009-03-19
HK1140139A1 (zh) 2010-10-08
WO2008021908A3 (en) 2008-08-14
US10143658B2 (en) 2018-12-04
US20190111000A1 (en) 2019-04-18
US20210338593A1 (en) 2021-11-04
JP2010500375A (ja) 2010-01-07

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