JP2010500360A5 - - Google Patents

Info

Publication number

JP2010500360A5

JP2010500360A5 JP2009523863A JP2009523863A JP2010500360A5 JP 2010500360 A5 JP2010500360 A5 JP 2010500360A5 JP 2009523863 A JP2009523863 A JP 2009523863A JP 2009523863 A JP2009523863 A JP 2009523863A JP 2010500360 A5 JP2010500360 A5 JP 2010500360A5

Authority

JP

Japan

Prior art keywords

soluble

tnf

receptor

use according

receptor protein

Prior art date

2007-08-10

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 102100040247 Tumor necrosis factor Human genes 0.000 claims 8
• 102000004127 Cytokines Human genes 0.000 claims 7
• 108090000695 Cytokines Proteins 0.000 claims 7
• 102000019223 Interleukin-1 receptor Human genes 0.000 claims 7
• 108050006617 Interleukin-1 receptor Proteins 0.000 claims 7
• 239000008194 pharmaceutical composition Substances 0.000 claims 7
• 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 6
• 230000002757 inflammatory effect Effects 0.000 claims 6
• 108010002352 Interleukin-1 Proteins 0.000 claims 5
• 102000000589 Interleukin-1 Human genes 0.000 claims 5
• 102100026018 Interleukin-1 receptor antagonist protein Human genes 0.000 claims 5
• 101710144554 Interleukin-1 receptor antagonist protein Proteins 0.000 claims 5
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• 102000003675 cytokine receptors Human genes 0.000 claims 5
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• MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 claims 4
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• XSDQTOBWRPYKKA-UHFFFAOYSA-N amiloride Chemical compound NC(=N)NC(=O)C1=NC(Cl)=C(N)N=C1N XSDQTOBWRPYKKA-UHFFFAOYSA-N 0.000 claims 1
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