JP2010075182A5 - - Google Patents

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Publication number
JP2010075182A5
JP2010075182A5 JP2009239501A JP2009239501A JP2010075182A5 JP 2010075182 A5 JP2010075182 A5 JP 2010075182A5 JP 2009239501 A JP2009239501 A JP 2009239501A JP 2009239501 A JP2009239501 A JP 2009239501A JP 2010075182 A5 JP2010075182 A5 JP 2010075182A5
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JP
Japan
Prior art keywords
seq
nucleic acid
kcnq3
mutation
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009239501A
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English (en)
Japanese (ja)
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JP5328603B2 (ja
JP2010075182A (ja
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Publication date
Application filed filed Critical
Publication of JP2010075182A publication Critical patent/JP2010075182A/ja
Publication of JP2010075182A5 publication Critical patent/JP2010075182A5/ja
Application granted granted Critical
Publication of JP5328603B2 publication Critical patent/JP5328603B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2009239501A 1997-10-24 2009-10-16 良性の家族性新生児痙攣（ｂｆｎｃ）および他の癲癇において突然変異されたｋｃｎｑ２およびｋｃｎｑ３−カリウムチャンネル遺伝子 Expired - Lifetime JP5328603B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6314797P 1997-10-24 1997-10-24
US60/063,147 1997-10-24

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2000517983A Division JP4520634B2 (ja) 1997-10-24 1998-10-23 良性の家族性新生児痙攣（ｂｆｎｃ）および他の癲癇において突然変異されたｋｃｎｑ２およびｋｃｎｑ３−カリウムチャンネル遺伝子

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013112986A Division JP5911823B2 (ja) 1997-10-24 2013-05-29 良性の家族性新生児痙攣（ｂｆｎｃ）および他の癲癇において突然変異されたｋｃｎｑ２およびｋｃｎｑ３−カリウムチャンネル遺伝子

Publications (3)

Publication Number Publication Date
JP2010075182A JP2010075182A (ja) 2010-04-08
JP2010075182A5 true JP2010075182A5 (https=) 2010-10-07
JP5328603B2 JP5328603B2 (ja) 2013-10-30

Family

ID=22047238

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2000517983A Expired - Lifetime JP4520634B2 (ja) 1997-10-24 1998-10-23 良性の家族性新生児痙攣（ｂｆｎｃ）および他の癲癇において突然変異されたｋｃｎｑ２およびｋｃｎｑ３−カリウムチャンネル遺伝子
JP2009239501A Expired - Lifetime JP5328603B2 (ja) 1997-10-24 2009-10-16 良性の家族性新生児痙攣（ｂｆｎｃ）および他の癲癇において突然変異されたｋｃｎｑ２およびｋｃｎｑ３−カリウムチャンネル遺伝子
JP2013112986A Expired - Lifetime JP5911823B2 (ja) 1997-10-24 2013-05-29 良性の家族性新生児痙攣（ｂｆｎｃ）および他の癲癇において突然変異されたｋｃｎｑ２およびｋｃｎｑ３−カリウムチャンネル遺伝子

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2000517983A Expired - Lifetime JP4520634B2 (ja) 1997-10-24 1998-10-23 良性の家族性新生児痙攣（ｂｆｎｃ）および他の癲癇において突然変異されたｋｃｎｑ２およびｋｃｎｑ３−カリウムチャンネル遺伝子

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013112986A Expired - Lifetime JP5911823B2 (ja) 1997-10-24 2013-05-29 良性の家族性新生児痙攣（ｂｆｎｃ）および他の癲癇において突然変異されたｋｃｎｑ２およびｋｃｎｑ３−カリウムチャンネル遺伝子

Country Status (5)

Country Link
US (3) US6413719B1 (https=)
EP (1) EP1037900A4 (https=)
JP (3) JP4520634B2 (https=)
CA (1) CA2307316C (https=)
WO (1) WO1999021875A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999007832A1 (en) 1997-08-12 1999-02-18 Bristol-Myers Squibb Company Kcnq potassium channels and methods of modulating same
EP1037900A4 (en) 1997-10-24 2006-08-30 Univ Utah Res Found KNCQ2 AND KNCQ3, GENES OF THE POTASSIUM CHANNEL HAVING MUTATION IN BENIGN FAMILY NEONATAL CONVULSIONS (BFNC) AND OTHER EPILEPSIES
AU2092700A (en) * 1999-01-26 2000-08-18 Neurosearch A/S Novel potassium channels and genes encoding these potassium channels
US6794161B1 (en) 1999-01-26 2004-09-21 Neurosearch A/S Potassium channels and genes encoding these potassium channels
JP4833467B2 (ja) * 1999-06-11 2011-12-07 ニューロサーチ、アクティーゼルスカブ 新規カリウムチャネル及び同カリウムチャネルをコードする遺伝子
US6649371B1 (en) 1999-06-11 2003-11-18 Neurosearch A/S Potassium channel KCNQ5 and sequences encoding the same
GB9915414D0 (en) * 1999-07-01 1999-09-01 Glaxo Group Ltd Medical use
US6472165B1 (en) * 1999-08-03 2002-10-29 Arzneimittelwerk Dresden Gmbh Modulatory binding site in potassium channels for screening and finding new active ingredients
EP1200086A4 (en) * 1999-08-04 2009-05-27 Icagen Inc THERAPEUTIC OR PROPHYLACTIC METHODS OF PAIN AND ANXIETY
DE1252330T1 (de) 1999-11-26 2003-11-27 Mcgill University, Montreal Loci der idiopathischen epilepsie, mutationen derselben und verfahren zu deren verwendung zur feststellung, prognose und behandlung von epilepsie
US6617131B2 (en) 2000-03-21 2003-09-09 Aventis Pharma Deutschland Gmbh Nucleic acid molecule encoding the potassium channel protein, KCNQ5
DE10013732A1 (de) * 2000-03-21 2001-09-27 Aventis Pharma Gmbh Das Kaliumkanalprotein KCNQ5, ein neuer Angriffspunkt bei Erkrankungen des zentralen Nervensystems und des Herz-Kreislauf-Systems
US6348486B1 (en) * 2000-10-17 2002-02-19 American Home Products Corporation Methods for modulating bladder function
US7537928B2 (en) * 2003-08-22 2009-05-26 Masonic Medical Research Laboratory Mutations in ion channel proteins associated with sudden cardiac death
CA2541836A1 (en) * 2003-10-13 2005-04-21 Bionomics Limited A diagnostic method for neonatal or infantile epilepsy syndromes
WO2006096648A2 (en) * 2005-03-07 2006-09-14 University Of Utah Research Foundation Mouse model
KR102361394B1 (ko) * 2017-12-28 2022-02-14 재단법인 대구경북과학기술원 뇌전증과 관련된 ｍｉＲＮＡ 및 그의 용도
KR102248910B1 (ko) * 2017-12-28 2021-05-06 재단법인대구경북과학기술원 뇌전증과 관련된 ｍｉＲＮＡ 및 그의 용도
CN111499758B (zh) * 2019-01-31 2023-01-31 中国科学院脑科学与智能技术卓越创新中心 筛选人钾离子通道调节剂的方法
BR112022004847A2 (pt) * 2019-09-17 2022-06-07 Knopp Biosciences Llc Método para tratar uma doença ou distúrbio de neurodesenvolvimento
WO2021178769A1 (en) * 2020-03-06 2021-09-10 Ionis Pharmaceuticals, Inc. Compounds and methods for modulating kcnq2

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5833975A (en) 1989-03-08 1998-11-10 Virogenetics Corporation Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence
US4675285A (en) * 1984-09-19 1987-06-23 Genetics Institute, Inc. Method for identification and isolation of DNA encoding a desired protein
ATE202571T1 (de) 1993-09-14 2001-07-15 Merck & Co Inc Humane protein-tyrosinphosphatase decodierende cdna
JP3619282B2 (ja) 1994-04-01 2005-02-09 中外製薬株式会社 ＩｇＧＦｃ部結合タンパク質をコードする遺伝子
DK0876491T3 (da) * 1995-12-22 2009-07-06 Univ Utah Res Found Langt QT-syndrom-gen, der koder for KVLQT1 og dets association med minK
JPH09191882A (ja) * 1996-01-16 1997-07-29 Japan Tobacco Inc ヒト新規ｋ＋チャネル蛋白質をコードするｄｎａおよびその断片
WO1999007832A1 (en) * 1997-08-12 1999-02-18 Bristol-Myers Squibb Company Kcnq potassium channels and methods of modulating same
EP1037900A4 (en) 1997-10-24 2006-08-30 Univ Utah Res Found KNCQ2 AND KNCQ3, GENES OF THE POTASSIUM CHANNEL HAVING MUTATION IN BENIGN FAMILY NEONATAL CONVULSIONS (BFNC) AND OTHER EPILEPSIES
GB9726339D0 (en) * 1997-12-13 1998-02-11 Zeneca Ltd Human-derived tissue-specific potassium channel

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