JP2009545534A5 - - Google Patents
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- Publication number
- JP2009545534A5 JP2009545534A5 JP2009522067A JP2009522067A JP2009545534A5 JP 2009545534 A5 JP2009545534 A5 JP 2009545534A5 JP 2009522067 A JP2009522067 A JP 2009522067A JP 2009522067 A JP2009522067 A JP 2009522067A JP 2009545534 A5 JP2009545534 A5 JP 2009545534A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- aryl
- compound according
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83542806P | 2006-08-04 | 2006-08-04 | |
| US60/835,428 | 2006-08-04 | ||
| PCT/CA2007/001357 WO2008014613A1 (en) | 2006-08-04 | 2007-08-01 | Multifunctional bioactive compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009545534A JP2009545534A (ja) | 2009-12-24 |
| JP2009545534A5 true JP2009545534A5 (https=) | 2010-02-12 |
| JP5357022B2 JP5357022B2 (ja) | 2013-12-04 |
Family
ID=38996830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009522067A Expired - Fee Related JP5357022B2 (ja) | 2006-08-04 | 2007-08-01 | 多機能生物活性化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8637521B2 (https=) |
| EP (1) | EP2046778B1 (https=) |
| JP (1) | JP5357022B2 (https=) |
| CN (1) | CN101511823B (https=) |
| AU (1) | AU2007280995C1 (https=) |
| BR (1) | BRPI0714616A2 (https=) |
| CA (1) | CA2659875C (https=) |
| EA (1) | EA018548B1 (https=) |
| MX (1) | MX2009001351A (https=) |
| WO (1) | WO2008014613A1 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
| EP1986679B1 (en) | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| CA2571645A1 (en) * | 2006-12-19 | 2008-06-19 | Apotex Technologies Inc. | Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture |
| CN101827626B (zh) | 2008-06-13 | 2015-03-18 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
| TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| EP2379511B1 (en) * | 2008-12-29 | 2014-12-17 | MannKind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| CA2749163A1 (en) | 2009-01-14 | 2010-07-22 | The Salk Institute For Biological Studies | Methods for screening and compounds that protect against amyloid diseases |
| DK2405963T3 (da) | 2009-03-11 | 2013-12-16 | Mannkind Corp | Apparat, system og fremgangsmåde til at måle modstand i en inhalator |
| KR102584844B1 (ko) | 2009-06-12 | 2023-10-04 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
| EP2464379B1 (en) * | 2009-08-10 | 2014-07-30 | Immunotech Developments Inc. | Vaccine having a peptide adjuvant for eliciting a specific immune response to treat influenza viral infection |
| CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| CN102985125A (zh) | 2010-06-21 | 2013-03-20 | 曼金德公司 | 干粉药物输送系统和方法 |
| SG194034A1 (en) | 2011-04-01 | 2013-11-29 | Mannkind Corp | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| MX2014004983A (es) | 2011-10-24 | 2014-09-22 | Mannkid Corp | Metodos y composiciones para tratar dolor. |
| EP2812313A4 (en) | 2012-02-09 | 2015-09-30 | Novus Int Inc | FUNCTIONALIZED POLYMERIC COMPOSITIONS |
| US9556167B2 (en) * | 2012-05-02 | 2017-01-31 | Yale University | TLR-agonist-conjugated antibody recruiting molecules (TLR-ARMs) |
| MX2015000395A (es) | 2012-07-12 | 2015-04-10 | Novus Int Inc | Composiciones de matriz y capa para proteccion de bioactivos. |
| KR102264177B1 (ko) | 2012-07-12 | 2021-06-11 | 맨카인드 코포레이션 | 건조 분말 약물 전달 시스템 및 방법 |
| WO2014016787A2 (en) | 2012-07-24 | 2014-01-30 | Pharma Bio Llc | Peptide-based compounds and uses thereof to treat beta-amyloid accumulation |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| EP3587404B1 (en) | 2013-03-15 | 2022-07-13 | MannKind Corporation | Microcrystalline diketopiperazine compositions, methods for preparation and use thereof |
| MX375448B (es) | 2013-07-18 | 2025-03-06 | Mannkind Corp | Composiciones farmacéuticas en polvo seco estables al calor y métodos. |
| EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| US10584306B2 (en) | 2017-08-11 | 2020-03-10 | Board Of Regents Of The University Of Oklahoma | Surfactant microemulsions |
| CN110054619A (zh) * | 2018-01-18 | 2019-07-26 | 西北农林科技大学 | 新型二酮哌嗪类组蛋白去乙酰化酶抑制剂 |
| CN113163918B (zh) * | 2018-08-28 | 2023-03-28 | 灵动科技（北京）有限公司 | 具有库存承载台车的自动驾驶系统 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4006261A (en) * | 1973-09-28 | 1977-02-01 | Firmenich S.A. | Flavoring with mixtures of theobromine and cyclic dipeptides |
| US4289759A (en) * | 1980-06-23 | 1981-09-15 | Ortho Pharmaceutical Corporation | Immunoregulatory diketopiperazine compounds |
| US4331595A (en) * | 1980-06-23 | 1982-05-25 | Ortho Pharmaceutical Corporation | Immunoregulatory diketopiperazine compounds |
| GB8427735D0 (en) * | 1984-11-02 | 1984-12-12 | Fujisawa Pharmaceutical Co | Piperazine compound |
| DE3909379A1 (de) | 1989-03-22 | 1990-09-27 | Cassella Ag | Thienylpiperazine, verfahren zu ihrer herstellung, ihre verwendung sowie diese enthaltende arzneimittel und deren herstellung |
| US6331318B1 (en) | 1994-09-30 | 2001-12-18 | Emisphere Technologies Inc. | Carbon-substituted diketopiperazine delivery systems |
| US5693338A (en) * | 1994-09-29 | 1997-12-02 | Emisphere Technologies, Inc. | Diketopiperazine-based delivery systems |
| FR2677361A1 (fr) * | 1991-06-04 | 1992-12-11 | Adir | Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| WO1993008815A1 (en) | 1991-10-28 | 1993-05-13 | Cytoven | Pharmaceutical dipeptide compositions and methods of use thereof |
| US5352461A (en) * | 1992-03-11 | 1994-10-04 | Pharmaceutical Discovery Corporation | Self assembling diketopiperazine drug delivery system |
| FR2722787B1 (fr) * | 1994-07-21 | 1996-10-11 | Univ Claude Bernard Lyon | Composes a activite anthelminthique: dicetopiperazines, precurseurs et analogues |
| US6103699A (en) * | 1996-06-07 | 2000-08-15 | Immunotech Developments Inc. | Peptide, a method for its preparation and a pharmaceutical composition containing the peptide |
| US6060452A (en) | 1996-03-13 | 2000-05-09 | Cytran, Inc. | Analogs of L-Glu-L-Trp having pharmacological activity |
| US5932579A (en) * | 1996-06-18 | 1999-08-03 | Affymax Technologies N.V. | Collagenase-1 and stromelysin-1 inhibitors, pharmaceutical compositions comprising same and methods of their use |
| JPH10226615A (ja) * | 1997-02-18 | 1998-08-25 | Pola Chem Ind Inc | アスパラギン酸フェニルアラニン環状ジペプタイド誘導体を含有する組成物 |
| US7026322B2 (en) | 1998-11-12 | 2006-04-11 | Nereus Pharmaceuticals, Inc. | Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds |
| DE19937721A1 (de) * | 1999-08-10 | 2001-02-15 | Max Planck Gesellschaft | Neue Diketopiperazine |
| US6974478B2 (en) | 1999-10-22 | 2005-12-13 | Archus Orthopedics, Inc. | Prostheses, systems and methods for replacement of natural facet joints with artificial facet joint surfaces |
| JP2001247566A (ja) * | 2000-03-03 | 2001-09-11 | Marine Biotechnol Inst Co Ltd | 新規抗カビ活性物質およびその製造法 |
| WO2002011676A2 (en) | 2000-08-04 | 2002-02-14 | Dmi Biosciences, Inc. | Method of using diketopiperazines and composition containing them |
| US20030171379A1 (en) * | 2001-12-28 | 2003-09-11 | Jacobs Robert S. | Methods of treating, preventing, or inhibiting inflammation with Mactanamide compounds |
| JP3846409B2 (ja) | 2002-02-15 | 2006-11-15 | 株式会社村田製作所 | 弾性表面波装置、通信装置 |
| EP1622633B1 (en) * | 2003-05-15 | 2016-02-24 | Ampio Pharmaceuticals, Inc. | Treatment of t-cell mediated diseases |
| KR20130066695A (ko) * | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
-
2007
- 2007-08-01 WO PCT/CA2007/001357 patent/WO2008014613A1/en not_active Ceased
- 2007-08-01 EA EA200970178A patent/EA018548B1/ru not_active IP Right Cessation
- 2007-08-01 AU AU2007280995A patent/AU2007280995C1/en not_active Ceased
- 2007-08-01 US US12/376,138 patent/US8637521B2/en not_active Expired - Fee Related
- 2007-08-01 JP JP2009522067A patent/JP5357022B2/ja not_active Expired - Fee Related
- 2007-08-01 CN CN200780033302.7A patent/CN101511823B/zh not_active Expired - Fee Related
- 2007-08-01 BR BRPI0714616-7A2A patent/BRPI0714616A2/pt not_active Application Discontinuation
- 2007-08-01 MX MX2009001351A patent/MX2009001351A/es active IP Right Grant
- 2007-08-01 EP EP07785022.0A patent/EP2046778B1/en active Active
- 2007-08-01 CA CA 2659875 patent/CA2659875C/en active Active
-
2013
- 2013-12-19 US US14/134,418 patent/US9108931B2/en active Active
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