JP2009545313A - ミオスタチンアンタゴニスト - Google Patents
ミオスタチンアンタゴニスト Download PDFInfo
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- JP2009545313A JP2009545313A JP2009522733A JP2009522733A JP2009545313A JP 2009545313 A JP2009545313 A JP 2009545313A JP 2009522733 A JP2009522733 A JP 2009522733A JP 2009522733 A JP2009522733 A JP 2009522733A JP 2009545313 A JP2009545313 A JP 2009545313A
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- myostatin
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018030432A1 (ja) * | 2016-08-10 | 2018-02-15 | 学校法人東京薬科大学 | ペプチドもしくはその薬学的に許容される塩、またはそれらのプロドラッグ |
| JP2020127430A (ja) * | 2014-11-06 | 2020-08-27 | スカラー ロック インコーポレイテッドＳｃｈｏｌａｒ Ｒｏｃｋ，Ｉｎｃ． | 抗プロ／潜在型−ミオスタチン抗体およびその使用 |
| WO2021060880A1 (ko) * | 2019-09-24 | 2021-04-01 | 마이오텍사이언스 주식회사 | 비천연 아미노산을 함유하는 근감소증의 예방 또는 치료용 약학적 조성물 |
| JP2021516252A (ja) * | 2018-03-21 | 2021-07-01 | 傅▲恵▼芳ＣＨＡＲＯＥＮＦＵＰＲＡＳＥＲＴ， Ｓｕｌａｗａｎ | 局部の筋肉増加を促進し、若しくは局部の筋萎縮を抑制又は防止する組成物及び当該組成物を使用して製造された薬物 |
| US12006359B2 (en) | 2016-01-08 | 2024-06-11 | Scholar Rock, Inc. | Methods for altering body composition by administering anti-pro/latent myostatin antibodies |
| US12338279B2 (en) | 2022-12-22 | 2025-06-24 | Scholar Rock, Inc. | Selective and potent inhibitory antibodies of myostatin activation |
| US12582712B2 (en) | 2015-09-15 | 2026-03-24 | Scholar Rock, Inc. | Method of making anti-pro/latent myostatin antibodies |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2582940A1 (en) * | 2004-09-30 | 2006-04-06 | Orico Limited | Myostatin isoform |
| ES2655877T3 (es) * | 2009-04-27 | 2018-02-22 | Novartis Ag | Composiciones y métodos para aumentar el crecimiento muscular |
| CN101659700B (zh) * | 2009-07-27 | 2011-11-16 | 广州罗森生物科技有限公司 | 一种短肽 |
| NZ599604A (en) * | 2009-10-01 | 2014-07-25 | Myostin Therapeutics Pty Ltd | Synthetic myostatin peptide antagonists |
| JO3340B1 (ar) * | 2010-05-26 | 2019-03-13 | Regeneron Pharma | مضادات حيوية لـعامل تمايز النمو 8 البشري |
| PH12013500315A1 (en) * | 2010-08-16 | 2013-04-29 | Amgen Inc | Antibodies that bind myostatin, compositions and methods |
| SMT201800092T1 (it) | 2011-11-14 | 2018-03-08 | Regeneron Pharma | Composizioni e metodi per aumentare la massa muscolare e la forza muscolare antagonizzando specificamente gdf8 e/o activina a |
| WO2016168613A1 (en) | 2015-04-15 | 2016-10-20 | Regeneron Pharmaceuticals, Inc. | Methods of increasing strength and functionality with gdf8 inhibitors |
| HRP20230308T1 (hr) * | 2017-01-06 | 2023-05-12 | Scholar Rock, Inc. | Liječenje metaboličkih bolesti putem inhibiranja aktivacije miostatina |
| IL276921B2 (en) | 2018-03-01 | 2025-12-01 | Regeneron Pharma | Methods for altering body composition |
| TWI649332B (zh) * | 2018-03-21 | 2019-02-01 | 英屬安圭拉商維多利亞生物醫學控股股份有限公司 | Composition for promoting local muscle growth, slowing or preventing local muscle atrophy and use thereof |
| CN112384247B (zh) * | 2018-07-02 | 2024-09-27 | 库拉米斯公司 | 利用细胞融合技术的基因及细胞治疗剂以及其的用途 |
| WO2020154034A1 (en) * | 2019-01-25 | 2020-07-30 | Children's Medical Center Corporation | Compositions and methods for treating muscular dystrophy and related disorders |
| EP3916009B1 (en) * | 2020-05-26 | 2023-06-28 | Sartorius Lab Instruments GmbH & Co. KG | Recombinant proteins based on fibrinogen |
| CN121343921A (zh) * | 2020-12-03 | 2026-01-16 | Lart生物有限公司 | 经工程化的细胞、经工程化的原肌肉生长抑制素蛋白、包含其的组合物及其生产方法 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2002504326A (ja) * | 1998-02-19 | 2002-02-12 | バイオスター インコーポレイティド | 脊椎動物被験体における免疫学的ミオスタチン調節法 |
| WO2005066204A2 (en) * | 2003-12-31 | 2005-07-21 | Schering-Plough Ltd. | Neutralizing epitope-based growth enhancing vaccine |
| WO2006083183A1 (en) * | 2005-02-07 | 2006-08-10 | Orico Limited | Use of myostatin (gdf-8) antagonists for treatment of sarcopenia (age-related muscle-wasting) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4847325A (en) * | 1988-01-20 | 1989-07-11 | Cetus Corporation | Conjugation of polymer to colony stimulating factor-1 |
| US7393682B1 (en) | 1993-03-19 | 2008-07-01 | The Johns Hopkins University School Of Medicine | Polynucleotides encoding promyostatin polypeptides |
| US5874409A (en) | 1995-06-07 | 1999-02-23 | La Jolla Pharmaceutical Company | APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies |
| AU6274298A (en) | 1997-02-05 | 1998-08-25 | Johns Hopkins University School Of Medicine, The | Growth differentiation factor-8 |
| US6656475B1 (en) | 1997-08-01 | 2003-12-02 | The Johns Hopkins University School Of Medicine | Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same |
| EE200200025A (et) | 1999-07-20 | 2003-04-15 | Pharmexa A/S | Meetod GDF-8 aktiivsuse allareguleerimiseks, meetod looma lihasmassi suurendamiseks, GDF-8 analoog,immunogeenne kompositsioon, nukleiinhappefragment, vektor, transformeeritud rakk ja selle valmistamismeetod, kompositsioon GDF-8 vastaste antikehadeto |
| EP1593689A3 (en) | 2000-01-18 | 2006-04-05 | Ovita Limited | Myostatin and mimetics thereof |
| JP2005533855A (ja) | 2002-07-24 | 2005-11-10 | インターツェル・アクチェンゲゼルシャフト | 病原性ウイルスからの別のリーディングフレームによりコードされる抗原 |
| AU2003267246A1 (en) | 2002-09-16 | 2004-04-30 | The Johns Hopkins University | Metalloprotease activation of myostatin, and methods of modulating myostatin activity |
| NZ529860A (en) * | 2003-11-28 | 2006-10-27 | Ovita Ltd | Muscle growth regulator mighty and use in promoting muscle mass and treating muscle wasting diseases |
| MX2007000976A (es) * | 2004-08-12 | 2007-04-10 | Wyeth Corp | Tratamiento combinado para diabetes, obesidad y enfermedades cardiovasculares utilizando inhibidores del factor 8 de crecimiento y diferenciacion. |
| US20070190056A1 (en) | 2006-02-07 | 2007-08-16 | Ravi Kambadur | Muscle regeneration compositions and uses therefor |
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- 2007-08-02 DK DK07834817.4T patent/DK2054434T3/en active
- 2007-08-02 WO PCT/NZ2007/000203 patent/WO2008016314A1/en not_active Ceased
- 2007-08-02 AU AU2007279456A patent/AU2007279456A1/en not_active Abandoned
- 2007-08-02 EP EP07834817.4A patent/EP2054434B1/en not_active Not-in-force
- 2007-08-02 US US12/376,289 patent/US8309068B2/en not_active Expired - Fee Related
- 2007-08-02 CN CN2007800366228A patent/CN101522707B/zh not_active Expired - Fee Related
- 2007-08-02 CA CA2693378A patent/CA2693378C/en not_active Expired - Fee Related
- 2007-08-02 JP JP2009522733A patent/JP2009545313A/ja active Pending
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2013
- 2013-09-27 JP JP2013201653A patent/JP5993827B2/ja not_active Expired - Fee Related
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2016
- 2016-04-01 JP JP2016074671A patent/JP2016130251A/ja not_active Withdrawn
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| JP2002504326A (ja) * | 1998-02-19 | 2002-02-12 | バイオスター インコーポレイティド | 脊椎動物被験体における免疫学的ミオスタチン調節法 |
| WO2005066204A2 (en) * | 2003-12-31 | 2005-07-21 | Schering-Plough Ltd. | Neutralizing epitope-based growth enhancing vaccine |
| WO2006083183A1 (en) * | 2005-02-07 | 2006-08-10 | Orico Limited | Use of myostatin (gdf-8) antagonists for treatment of sarcopenia (age-related muscle-wasting) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11925683B2 (en) | 2014-11-06 | 2024-03-12 | Scholar Rock, Inc. | Compositions for making and using anti-Myostatin antibodies |
| JP2020127430A (ja) * | 2014-11-06 | 2020-08-27 | スカラー ロック インコーポレイテッドＳｃｈｏｌａｒ Ｒｏｃｋ，Ｉｎｃ． | 抗プロ／潜在型−ミオスタチン抗体およびその使用 |
| US12661400B2 (en) | 2014-11-06 | 2026-06-23 | Scholar Rock, Inc. | Methods of treating myopathies with anti-pro/latent myostatin antibodies |
| JP2022166238A (ja) * | 2014-11-06 | 2022-11-01 | スカラー ロック インコーポレイテッド | 抗プロ／潜在型－ミオスタチン抗体およびその使用 |
| JP2024109663A (ja) * | 2014-11-06 | 2024-08-14 | スカラー ロック インコーポレイテッド | 抗プロ／潜在型－ミオスタチン抗体およびその使用 |
| US12582712B2 (en) | 2015-09-15 | 2026-03-24 | Scholar Rock, Inc. | Method of making anti-pro/latent myostatin antibodies |
| US12006359B2 (en) | 2016-01-08 | 2024-06-11 | Scholar Rock, Inc. | Methods for altering body composition by administering anti-pro/latent myostatin antibodies |
| US11566047B2 (en) | 2016-08-10 | 2023-01-31 | Tokyo University Of Pharmacy & Life Sciences | Peptide or pharmaceutically acceptable salt thereof, or prodrug thereof |
| WO2018030432A1 (ja) * | 2016-08-10 | 2018-02-15 | 学校法人東京薬科大学 | ペプチドもしくはその薬学的に許容される塩、またはそれらのプロドラッグ |
| JP7183291B2 (ja) | 2018-03-21 | 2022-12-05 | 松陽生技股▲分▼有限公司 | 局部の筋肉増加を促進し、若しくは局部の筋萎縮を抑制又は防止する組成物及び当該組成物を使用して製造された薬物 |
| JP2021516252A (ja) * | 2018-03-21 | 2021-07-01 | 傅▲恵▼芳ＣＨＡＲＯＥＮＦＵＰＲＡＳＥＲＴ， Ｓｕｌａｗａｎ | 局部の筋肉増加を促進し、若しくは局部の筋萎縮を抑制又は防止する組成物及び当該組成物を使用して製造された薬物 |
| WO2021060880A1 (ko) * | 2019-09-24 | 2021-04-01 | 마이오텍사이언스 주식회사 | 비천연 아미노산을 함유하는 근감소증의 예방 또는 치료용 약학적 조성물 |
| US12338279B2 (en) | 2022-12-22 | 2025-06-24 | Scholar Rock, Inc. | Selective and potent inhibitory antibodies of myostatin activation |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2693378A1 (en) | 2008-02-07 |
| EP2054434A4 (en) | 2011-07-13 |
| WO2008016314A1 (en) | 2008-02-07 |
| EP2054434B1 (en) | 2017-03-15 |
| CA2693378C (en) | 2020-04-14 |
| JP5993827B2 (ja) | 2016-09-14 |
| BRPI0715072A2 (pt) | 2013-06-25 |
| JP2016130251A (ja) | 2016-07-21 |
| JP2014057584A (ja) | 2014-04-03 |
| CN101522707B (zh) | 2013-08-28 |
| CN101522707A (zh) | 2009-09-02 |
| US8309068B2 (en) | 2012-11-13 |
| AU2007279456A1 (en) | 2008-02-07 |
| DK2054434T3 (en) | 2017-07-03 |
| US20090324590A1 (en) | 2009-12-31 |
| EP2054434A1 (en) | 2009-05-06 |
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