JP2009545309A5 - - Google Patents
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- Publication number
- JP2009545309A5 JP2009545309A5 JP2009522414A JP2009522414A JP2009545309A5 JP 2009545309 A5 JP2009545309 A5 JP 2009545309A5 JP 2009522414 A JP2009522414 A JP 2009522414A JP 2009522414 A JP2009522414 A JP 2009522414A JP 2009545309 A5 JP2009545309 A5 JP 2009545309A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- mirna
- molecule
- mammalian
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 31
- 108091070501 miRNA Proteins 0.000 claims 25
- 239000002679 microRNA Substances 0.000 claims 25
- 238000000034 method Methods 0.000 claims 18
- 239000003112 inhibitor Substances 0.000 claims 8
- 230000001939 inductive effect Effects 0.000 claims 7
- 150000007523 nucleic acids Chemical group 0.000 claims 7
- 239000002243 precursor Substances 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 238000004113 cell culture Methods 0.000 claims 4
- 230000012010 growth Effects 0.000 claims 4
- 108091070493 Homo sapiens miR-21 stem-loop Proteins 0.000 claims 3
- 108091008065 MIR21 Proteins 0.000 claims 3
- 239000002028 Biomass Substances 0.000 claims 2
- 108091026890 Coding region Proteins 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 230000022131 cell cycle Effects 0.000 claims 2
- 241000699800 Cricetinae Species 0.000 claims 1
- 241000699802 Cricetulus griseus Species 0.000 claims 1
- 230000003698 anagen phase Effects 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 239000000411 inducer Substances 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 210000003734 kidney Anatomy 0.000 claims 1
- 210000001672 ovary Anatomy 0.000 claims 1
- 230000035897 transcription Effects 0.000 claims 1
- 238000013518 transcription Methods 0.000 claims 1
- 230000002103 transcriptional effect Effects 0.000 claims 1
- 238000003146 transient transfection Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE20060587 | 2006-08-04 | ||
| PCT/IE2007/000078 WO2008015662A1 (en) | 2006-08-04 | 2007-08-03 | A method of producing recombinant biological products |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009545309A JP2009545309A (ja) | 2009-12-24 |
| JP2009545309A5 true JP2009545309A5 (enExample) | 2010-09-16 |
Family
ID=38720408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009522414A Pending JP2009545309A (ja) | 2006-08-04 | 2007-08-03 | 組換え型生物学的製剤を製造する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8476244B2 (enExample) |
| EP (1) | EP2046970B2 (enExample) |
| JP (1) | JP2009545309A (enExample) |
| CN (1) | CN101541972A (enExample) |
| AU (1) | AU2007280004A1 (enExample) |
| CA (1) | CA2658301A1 (enExample) |
| WO (1) | WO2008015662A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2520649A3 (en) * | 2007-11-23 | 2013-02-20 | Panagene, Inc. | MicroRNA antisense PNAs, compositions comprising the same, and methods for using and evaluating the same |
| MX374424B (es) | 2012-05-21 | 2025-03-06 | Genentech Inc | Metodos para mejorar la seguridad del transporte de la barrera hematoencefalica. |
| EP3536789A1 (en) * | 2012-06-06 | 2019-09-11 | Boehringer Ingelheim International GmbH | Cell engineering using rnas |
| ES2743506T3 (es) | 2013-03-14 | 2020-02-19 | Medimmune Llc | Producción de polipéptidos recombinantes |
| WO2014204405A1 (en) * | 2013-06-18 | 2014-12-24 | Agency For Science, Technology And Research | Method for modulating recombinant protein production |
| CN105849265B (zh) * | 2013-08-06 | 2021-03-26 | 英国龙沙生物医药股份有限公司 | 用于产生供生产重组蛋白的哺乳动物生产细胞的物品和方法 |
| PL3063278T3 (pl) * | 2013-11-01 | 2018-08-31 | Sementis Limited | Wytwarzanie wektora wirusowego |
| DE102017128356B4 (de) | 2017-11-30 | 2024-10-10 | TRUMPF Laser SE | Scanspiegel und Scanspiegel-Einheit für ein Laser-Scansystem |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20000006549A (ko) * | 1998-06-30 | 2000-01-25 | 윤재승 | 생체내혈소판증식효능이향상된신규한트롬보포이에틴유도체 |
| EP2530157B1 (en) * | 2003-07-31 | 2016-09-28 | Regulus Therapeutics Inc. | Oligomeric compounds and compositions for use in modulation of miRNAs |
| US8106180B2 (en) * | 2003-08-07 | 2012-01-31 | Whitehead Institute For Biomedical Research | Methods and products for expression of micro RNAs |
| EP1791954A1 (en) * | 2004-09-07 | 2007-06-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Agents, compositions and methods for treating pathologies in which regulating an ache-associated biological pathway is beneficial |
| CA2857878A1 (en) † | 2004-11-12 | 2006-12-28 | Asuragen, Inc. | Methods and compositions involving mirna and mirna inhibitor molecules |
| WO2006133022A2 (en) † | 2005-06-03 | 2006-12-14 | The Johns Hopkins University | Compositions and methods for decreasing microrna expression for the treatment of neoplasia |
| EP2377559A1 (en) † | 2005-06-03 | 2011-10-19 | Southern Adelaide Health Service - Flinders Medical Centre | Targeting cells with altered microRNA expression |
-
2007
- 2007-08-03 CA CA002658301A patent/CA2658301A1/en not_active Abandoned
- 2007-08-03 JP JP2009522414A patent/JP2009545309A/ja active Pending
- 2007-08-03 CN CNA2007800318741A patent/CN101541972A/zh active Pending
- 2007-08-03 US US12/376,345 patent/US8476244B2/en not_active Expired - Fee Related
- 2007-08-03 EP EP07789931.8A patent/EP2046970B2/en not_active Ceased
- 2007-08-03 AU AU2007280004A patent/AU2007280004A1/en not_active Abandoned
- 2007-08-03 WO PCT/IE2007/000078 patent/WO2008015662A1/en not_active Ceased
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