CN101541972A - 生产重组生物产品的方法 - Google Patents

生产重组生物产品的方法 Download PDF

Info

Publication number
CN101541972A
CN101541972A CNA2007800318741A CN200780031874A CN101541972A CN 101541972 A CN101541972 A CN 101541972A CN A2007800318741 A CNA2007800318741 A CN A2007800318741A CN 200780031874 A CN200780031874 A CN 200780031874A CN 101541972 A CN101541972 A CN 101541972A
Authority
CN
China
Prior art keywords
cell
mirna
mammals
mirna molecule
mir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800318741A
Other languages
English (en)
Chinese (zh)
Inventor
帕克·加梅尔
尼奥·布鲁恩
马丁·科莱尼斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dublin City University
Original Assignee
Dublin City University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38720408&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101541972(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dublin City University filed Critical Dublin City University
Publication of CN101541972A publication Critical patent/CN101541972A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/50—Methods for regulating/modulating their activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA2007800318741A 2006-08-04 2007-08-03 生产重组生物产品的方法 Pending CN101541972A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE20060587 2006-08-04
IES2006/0587 2006-08-04

Publications (1)

Publication Number Publication Date
CN101541972A true CN101541972A (zh) 2009-09-23

Family

ID=38720408

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800318741A Pending CN101541972A (zh) 2006-08-04 2007-08-03 生产重组生物产品的方法

Country Status (7)

Country Link
US (1) US8476244B2 (enExample)
EP (1) EP2046970B2 (enExample)
JP (1) JP2009545309A (enExample)
CN (1) CN101541972A (enExample)
AU (1) AU2007280004A1 (enExample)
CA (1) CA2658301A1 (enExample)
WO (1) WO2008015662A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105229159A (zh) * 2013-03-14 2016-01-06 米迪缪尼有限公司 重组多肽生产
CN105849265A (zh) * 2013-08-06 2016-08-10 英国龙沙生物医药股份有限公司 用于产生供生产重组蛋白的哺乳动物生产细胞的物品和方法
CN106255758A (zh) * 2013-11-01 2016-12-21 赛门蒂斯有限公司 病毒载体制造

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2520649A3 (en) * 2007-11-23 2013-02-20 Panagene, Inc. MicroRNA antisense PNAs, compositions comprising the same, and methods for using and evaluating the same
MX374424B (es) 2012-05-21 2025-03-06 Genentech Inc Metodos para mejorar la seguridad del transporte de la barrera hematoencefalica.
EP3536789A1 (en) * 2012-06-06 2019-09-11 Boehringer Ingelheim International GmbH Cell engineering using rnas
WO2014204405A1 (en) * 2013-06-18 2014-12-24 Agency For Science, Technology And Research Method for modulating recombinant protein production
DE102017128356B4 (de) 2017-11-30 2024-10-10 TRUMPF Laser SE Scanspiegel und Scanspiegel-Einheit für ein Laser-Scansystem

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000006549A (ko) * 1998-06-30 2000-01-25 윤재승 생체내혈소판증식효능이향상된신규한트롬보포이에틴유도체
EP2530157B1 (en) * 2003-07-31 2016-09-28 Regulus Therapeutics Inc. Oligomeric compounds and compositions for use in modulation of miRNAs
US8106180B2 (en) * 2003-08-07 2012-01-31 Whitehead Institute For Biomedical Research Methods and products for expression of micro RNAs
EP1791954A1 (en) * 2004-09-07 2007-06-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Agents, compositions and methods for treating pathologies in which regulating an ache-associated biological pathway is beneficial
CA2857878A1 (en) † 2004-11-12 2006-12-28 Asuragen, Inc. Methods and compositions involving mirna and mirna inhibitor molecules
WO2006133022A2 (en) † 2005-06-03 2006-12-14 The Johns Hopkins University Compositions and methods for decreasing microrna expression for the treatment of neoplasia
EP2377559A1 (en) † 2005-06-03 2011-10-19 Southern Adelaide Health Service - Flinders Medical Centre Targeting cells with altered microRNA expression

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105229159A (zh) * 2013-03-14 2016-01-06 米迪缪尼有限公司 重组多肽生产
CN105229159B (zh) * 2013-03-14 2021-07-06 米迪缪尼有限公司 重组多肽生产
CN105849265A (zh) * 2013-08-06 2016-08-10 英国龙沙生物医药股份有限公司 用于产生供生产重组蛋白的哺乳动物生产细胞的物品和方法
CN105849265B (zh) * 2013-08-06 2021-03-26 英国龙沙生物医药股份有限公司 用于产生供生产重组蛋白的哺乳动物生产细胞的物品和方法
CN106255758A (zh) * 2013-11-01 2016-12-21 赛门蒂斯有限公司 病毒载体制造
CN106255758B (zh) * 2013-11-01 2020-06-23 赛门蒂斯有限公司 病毒载体制造

Also Published As

Publication number Publication date
EP2046970A1 (en) 2009-04-15
US20100190258A1 (en) 2010-07-29
JP2009545309A (ja) 2009-12-24
WO2008015662A8 (en) 2009-07-23
WO2008015662A1 (en) 2008-02-07
US8476244B2 (en) 2013-07-02
EP2046970B2 (en) 2020-04-29
CA2658301A1 (en) 2008-02-07
AU2007280004A1 (en) 2008-02-07
EP2046970B1 (en) 2014-01-08

Similar Documents

Publication Publication Date Title
Ji et al. Identification of microRNA‐181 by genome‐wide screening as a critical player in EpCAM–positive hepatic cancer stem cells
He et al. Small RNA molecules in the regulation of spermatogenesis
Barroso-delJesus et al. Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoter
WO2009002462A1 (en) Pre-mirna loop-modulated target regulation
WO2008084319A2 (ja) 新規核酸
CN107287242A (zh) 一种促进牛骨骼肌卫星细胞成肌分化的方法
US8476244B2 (en) Method of producing recombinant biological products
CN111387105B (zh) 一种全雄罗氏沼虾制种的方法
CN106032532A (zh) 一种小激活rna及其制备方法和应用
Hayashi et al. Mesenchymal miR-21 regulates branching morphogenesis in murine submandibular gland in vitro
Hai et al. Chi-miR-370-3p regulates hair follicle morphogenesis of Inner Mongolian cashmere goats
Wu et al. Chi-miR-130b-3p regulates Inner Mongolia cashmere goat skin hair follicles in fetuses by targeting Wnt family member 10A
Bu et al. Identification and characterization of microRNA sequences from bovine mammary epithelial cells
US10669541B2 (en) Means and methods for the generation of mammalian producer cells for the production of recombinant proteins
CN109182562A (zh) 与蛋鸭卵泡发育相关的miRNA apla-mir-25-42及其检测引物、抑制物和应用
CN113122539B (zh) 一种驴Zfy基因的RNA干扰片段、表达载体及其应用
CN109402118A (zh) 与蛋鸭卵泡发育相关的miRNA apla-mir-145-4及其检测引物、抑制物和应用
CN101591652B (zh) 两种抑制“肌肉生长抑制素基因”表达的合成小干扰rna分子
CN103589730A (zh) 一种抑制IRS1基因表达的shRNA及应用
CN119061016A (zh) 半滑舌鳎组蛋白及其变体小rna在半滑舌鳎性别分化中的应用
CN106399308A (zh) zfy基因的RNA干扰片段、表达载体及其应用
US20110294692A1 (en) Use of mir-126 for enhancing hematopoietic stem cell engraftment, for isolating hematopoietic stem cells, and for treating and monitoring the treatment of acute myeloid leukemia
Ratnadiwakara et al. SRSF3 confers selective processing of miR-17-92 cluster to promote tumorigenic properties in colorectal cancer
CN104232643A (zh) RNAi干扰片段、干扰载体、制备方法及其应用
Meng et al. Comparative alternative polyadenylation profiles in differentiated adipocytes of subcutaneous and intramuscular fat tissue in cattle

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Open date: 20090923