JP2009544711A - 疾病の治療方法及び疾病治療用組成物 - Google Patents

疾病の治療方法及び疾病治療用組成物 Download PDF

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JP2009544711A
JP2009544711A JP2009521823A JP2009521823A JP2009544711A JP 2009544711 A JP2009544711 A JP 2009544711A JP 2009521823 A JP2009521823 A JP 2009521823A JP 2009521823 A JP2009521823 A JP 2009521823A JP 2009544711 A JP2009544711 A JP 2009544711A
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cells
cell
polynucleotide
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JP2009544711A5 (enExample
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リード,トマス,ディー.
ビーチ,ロバート,ピー.
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イントレクソン コーポレイション
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081Purging biological preparations of unwanted cells
    • C12N5/0093Purging against cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
    • C12N2501/72Transferases [EC 2.]
    • C12N2501/724Glycosyltransferases (EC 2.4.)
    • CCHEMISTRY; METALLURGY
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    • C12N2510/00Genetically modified cells
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/02Pentosyltransferases (2.4.2)
    • C12Y204/02036NAD(+)--diphthamide ADP-ribosyltransferase (2.4.2.36)

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  • Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2009521823A 2006-07-26 2007-07-26 疾病の治療方法及び疾病治療用組成物 Pending JP2009544711A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82038106P 2006-07-26 2006-07-26
US88909507P 2007-02-09 2007-02-09
PCT/US2007/016747 WO2008073154A2 (en) 2006-07-26 2007-07-26 Methods and compositions for treating disease

Publications (2)

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JP2009544711A true JP2009544711A (ja) 2009-12-17
JP2009544711A5 JP2009544711A5 (enExample) 2010-09-09

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JP2009521823A Pending JP2009544711A (ja) 2006-07-26 2007-07-26 疾病の治療方法及び疾病治療用組成物

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US (3) US20100003226A1 (enExample)
EP (1) EP2043662B1 (enExample)
JP (1) JP2009544711A (enExample)
KR (1) KR20090035011A (enExample)
AU (1) AU2007332980A1 (enExample)
CA (1) CA2658836C (enExample)
DK (1) DK2043662T3 (enExample)
ES (1) ES2553332T3 (enExample)
HU (1) HUE027142T2 (enExample)
IL (1) IL196638A (enExample)
MX (1) MX2009000966A (enExample)
NZ (1) NZ575075A (enExample)
PL (1) PL2043662T3 (enExample)
PT (1) PT2043662E (enExample)
RU (1) RU2468820C2 (enExample)
WO (1) WO2008073154A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018207808A1 (ja) * 2017-05-09 2018-11-15 学校法人 慶應義塾 脳腫瘍治療用細胞製剤

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WO2013109944A1 (en) * 2012-01-18 2013-07-25 The Trustees Of The University Of Pennsylvania Methods for assessing risk for cancer using biomarkers
KR102452803B1 (ko) 2012-05-09 2022-10-07 캔텍스 파마슈티칼즈, 인크. 골수억제의 치료
WO2016133907A1 (en) * 2015-02-17 2016-08-25 Cantex Pharmaceuticals, Inc. Adoptive cell transfer methods
EP3258941A4 (en) 2015-02-17 2018-09-26 Cantex Pharmaceuticals, Inc. Treatment of cancers and hematopoietic stem cell disorders privileged by cxcl12-cxcr4 interaction
JP6976244B2 (ja) 2015-11-11 2021-12-08 プレシゲン,インコーポレイテッド 心臓状態および他の病態の処置のための複数の生物学的に活性なポリペプチドを単一のベクターから発現させるための組成物および方法

Citations (5)

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JPH09510352A (ja) * 1994-03-15 1997-10-21 プリズム ファーマシューティカルズ,インコーポレイティド 遺伝子療法及び前部の眼疾患のためのヘパリン結合成長因子
JPH11505805A (ja) * 1995-05-16 1999-05-25 プリズム ファーマシューティカルズ,インコーポレイテッド 治療的処置のための核酸およびリガンドを含有する組成物
JP2002504340A (ja) * 1998-02-19 2002-02-12 セイント.ジュード チルドレンズ リサーチ ホスピタル ヒト腫瘍細胞類を感作しおよびヒト腫瘍細胞の増殖を阻害するための組成物および方法
JP2002515784A (ja) * 1996-06-24 2002-05-28 セレクティブ ジェネティクス,インコーポレイテッド ヘパリン結合増殖因子結合体を含有するヘパリン処理医療用デバイス
JP2004532004A (ja) * 2001-01-19 2004-10-21 ルードビッヒ、インスティテュート、フォー、キャンサー、リサーチ 腫瘍画像化のターゲットとしてのF1t4(VEGFR−3)および抗腫瘍療法

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US20040033600A1 (en) 2001-03-21 2004-02-19 Palli Subba Reddy Ecdysone receptor-based inducible gene expression system
EP1266015B1 (en) 2000-03-22 2006-08-30 RheoGene Holdings Inc. Ecdysone receptor-based inducible gene expression system
DK1311661T3 (da) * 2000-08-14 2012-11-26 Us Gov Health & Human Serv Forøget homolog rekombination medieret ved lambda-rekombinationsproteiner
US8105825B2 (en) 2000-10-03 2012-01-31 Intrexon Corporation Multiple inducible gene regulation system
JP4994563B2 (ja) 2001-02-20 2012-08-08 イントレキソン コーポレーション 新規置換突然変異体受容体および核受容体−ベースの誘導性遺伝子発現システムにおけるその使用
JP4955905B2 (ja) 2001-02-20 2012-06-20 イントレキソン コーポレーション キメラレチノイドx受容体および新規エクジソン受容体−ベースの誘導性遺伝子発現システムにおけるそれらの使用
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Publication number Priority date Publication date Assignee Title
JPH09510352A (ja) * 1994-03-15 1997-10-21 プリズム ファーマシューティカルズ,インコーポレイティド 遺伝子療法及び前部の眼疾患のためのヘパリン結合成長因子
JPH11505805A (ja) * 1995-05-16 1999-05-25 プリズム ファーマシューティカルズ,インコーポレイテッド 治療的処置のための核酸およびリガンドを含有する組成物
JP2002515784A (ja) * 1996-06-24 2002-05-28 セレクティブ ジェネティクス,インコーポレイテッド ヘパリン結合増殖因子結合体を含有するヘパリン処理医療用デバイス
JP2002504340A (ja) * 1998-02-19 2002-02-12 セイント.ジュード チルドレンズ リサーチ ホスピタル ヒト腫瘍細胞類を感作しおよびヒト腫瘍細胞の増殖を阻害するための組成物および方法
JP2004532004A (ja) * 2001-01-19 2004-10-21 ルードビッヒ、インスティテュート、フォー、キャンサー、リサーチ 腫瘍画像化のターゲットとしてのF1t4(VEGFR−3)および抗腫瘍療法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018207808A1 (ja) * 2017-05-09 2018-11-15 学校法人 慶應義塾 脳腫瘍治療用細胞製剤
JPWO2018207808A1 (ja) * 2017-05-09 2020-03-12 学校法人慶應義塾 脳腫瘍治療用細胞製剤
JP7051060B2 (ja) 2017-05-09 2022-04-11 学校法人慶應義塾 脳腫瘍治療用細胞製剤

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Publication number Publication date
HK1129596A1 (en) 2009-12-04
US20170191027A1 (en) 2017-07-06
MX2009000966A (es) 2009-03-05
IL196638A (en) 2013-11-28
EP2043662B1 (en) 2015-09-09
HUE027142T2 (en) 2016-08-29
IL196638A0 (en) 2009-11-18
ES2553332T3 (es) 2015-12-07
CA2658836A1 (en) 2008-06-19
NZ575075A (en) 2011-10-28
RU2009103208A (ru) 2010-09-10
KR20090035011A (ko) 2009-04-08
US20100003226A1 (en) 2010-01-07
DK2043662T3 (en) 2015-12-14
CA2658836C (en) 2017-11-28
EP2043662A4 (en) 2010-04-14
PT2043662E (pt) 2015-11-25
AU2007332980A1 (en) 2008-06-19
WO2008073154A3 (en) 2008-12-04
RU2468820C2 (ru) 2012-12-10
EP2043662A2 (en) 2009-04-08
PL2043662T3 (pl) 2016-03-31
WO2008073154A2 (en) 2008-06-19
US20150132265A1 (en) 2015-05-14

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