JP2009544599A5 - - Google Patents

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Publication number
JP2009544599A5
JP2009544599A5 JP2009519995A JP2009519995A JP2009544599A5 JP 2009544599 A5 JP2009544599 A5 JP 2009544599A5 JP 2009519995 A JP2009519995 A JP 2009519995A JP 2009519995 A JP2009519995 A JP 2009519995A JP 2009544599 A5 JP2009544599 A5 JP 2009544599A5
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JP
Japan
Prior art keywords
alkyl
tetrahydro
dioxo
cycloalkyl
lambda
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009519995A
Other languages
English (en)
Japanese (ja)
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JP2009544599A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2007/057540 external-priority patent/WO2008009750A2/en
Publication of JP2009544599A publication Critical patent/JP2009544599A/ja
Publication of JP2009544599A5 publication Critical patent/JP2009544599A5/ja
Withdrawn legal-status Critical Current

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JP2009519995A 2006-07-20 2007-07-20 Ｂａｃｅ阻害剤として有用な大環状化合物 Withdrawn JP2009544599A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06117571 2006-07-20
PCT/EP2007/057540 WO2008009750A2 (en) 2006-07-20 2007-07-20 Macrocyclic compounds useful as bace inhibitors

Publications (2)

Publication Number Publication Date
JP2009544599A JP2009544599A (ja) 2009-12-17
JP2009544599A5 true JP2009544599A5 (https=) 2010-08-26

Family

ID=37467481

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009519995A Withdrawn JP2009544599A (ja) 2006-07-20 2007-07-20 Ｂａｃｅ阻害剤として有用な大環状化合物

Country Status (11)

Country Link
US (1) US20090312370A1 (https=)
EP (1) EP2046761A2 (https=)
JP (1) JP2009544599A (https=)
KR (1) KR20090039726A (https=)
CN (1) CN101490018A (https=)
AU (1) AU2007275067A1 (https=)
BR (1) BRPI0715440A2 (https=)
CA (1) CA2657280A1 (https=)
MX (1) MX2009000710A (https=)
RU (1) RU2009105762A (https=)
WO (1) WO2008009750A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0325830D0 (en) * 2003-11-05 2003-12-10 Novartis Ag Organic compounds
US20080132477A1 (en) * 2005-01-13 2008-06-05 Claudia Betschart Macrocyclic Compounds Useful as Bace Inhibitors
GB0500683D0 (en) * 2005-01-13 2005-02-23 Novartis Ag Organic compounds
GB0526614D0 (en) 2005-12-30 2006-02-08 Novartis Ag Organic compounds
CA2656869A1 (en) * 2006-07-20 2008-01-24 Novartis Ag Macrocyclic lactams
CN104619707A (zh) 2012-07-31 2015-05-13 协和发酵麒麟株式会社 稠环杂环化合物
US20140371283A1 (en) 2013-02-12 2014-12-18 Buck Institute For Research On Aging Hydantoins that modulate bace-mediated app processing
CN108732355B (zh) * 2017-04-25 2021-06-25 首都医科大学附属北京安定医院 一种测定bace1酶切nrg1活性的检测方法及其试剂盒

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002100856A1 (en) * 2001-06-12 2002-12-19 Elan Pharmaceuticals, Inc. Macrocycles useful in the treatment of alzheimer's disease
BR0210391A (pt) * 2001-06-12 2004-06-15 Elan Pharm Inc Composto, métodos de tratar um paciente que tenha ou de prevenir um paciente de contrair uma doença ou condição e de preparar um composto, e, uso de um composto
GB0325830D0 (en) * 2003-11-05 2003-12-10 Novartis Ag Organic compounds
US20080132477A1 (en) * 2005-01-13 2008-06-05 Claudia Betschart Macrocyclic Compounds Useful as Bace Inhibitors
GB0500683D0 (en) * 2005-01-13 2005-02-23 Novartis Ag Organic compounds
GB0526614D0 (en) * 2005-12-30 2006-02-08 Novartis Ag Organic compounds
CA2656869A1 (en) * 2006-07-20 2008-01-24 Novartis Ag Macrocyclic lactams
MX2009000769A (es) * 2006-07-21 2009-01-28 Novartis Ag Compuestos de 2,4-di(arilaminio)-pirimidin-5-carboxamida como inhibidores de cinasas jak.

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