JP2009541438A - 治療用化合物 - Google Patents

治療用化合物 Download PDF

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Publication number
JP2009541438A
JP2009541438A JP2009517175A JP2009517175A JP2009541438A JP 2009541438 A JP2009541438 A JP 2009541438A JP 2009517175 A JP2009517175 A JP 2009517175A JP 2009517175 A JP2009517175 A JP 2009517175A JP 2009541438 A JP2009541438 A JP 2009541438A
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Japan
Prior art keywords
compound
formula
pain
producing
reacted
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JP2009517175A
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English (en)
Japanese (ja)
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JP2009541438A5 (https=
Inventor
マイケル・ヒギンボトム
エドワード・ダニエル・サボリー
ギルス・アルバート・ブラウン
ヴィエタン・アンヌ・ホーガン
エマ・ジェイン・チャップマン
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Swedish Orphan Biovitrum AB
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Biovitrum AB
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Publication of JP2009541438A publication Critical patent/JP2009541438A/ja
Publication of JP2009541438A5 publication Critical patent/JP2009541438A5/ja
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P13/12Drugs for disorders of the urinary system of the kidneys
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P27/02Ophthalmic agents
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    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
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    • AHUMAN NECESSITIES
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    • A61P31/14Antivirals for RNA viruses
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    • AHUMAN NECESSITIES
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    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
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    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
JP2009517175A 2006-06-27 2007-06-26 治療用化合物 Withdrawn JP2009541438A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0601398 2006-06-27
US83714606P 2006-08-11 2006-08-11
PCT/EP2007/056378 WO2008000745A2 (en) 2006-06-27 2007-06-26 Adenosine derivatives for the treatment of pain

Publications (2)

Publication Number Publication Date
JP2009541438A true JP2009541438A (ja) 2009-11-26
JP2009541438A5 JP2009541438A5 (https=) 2010-08-05

Family

ID=38537489

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009517175A Withdrawn JP2009541438A (ja) 2006-06-27 2007-06-26 治療用化合物

Country Status (9)

Country Link
US (1) US7807685B2 (https=)
EP (1) EP2081946B1 (https=)
JP (1) JP2009541438A (https=)
CN (1) CN101479289A (https=)
AU (1) AU2007263728A1 (https=)
CA (1) CA2654375A1 (https=)
NZ (1) NZ573308A (https=)
RU (1) RU2441875C2 (https=)
WO (1) WO2008000745A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014510743A (ja) * 2011-03-31 2014-05-01 シェファー、コンスタンツェ 核酸の非ウイルスの導入のためのパーフルオロ化化合物
WO2020235658A1 (ja) * 2019-05-21 2020-11-26 株式会社四国核酸化学 オリゴヌクレオチド合成に用いるマルチフルオラスブロックマーおよびこれを用いたオリゴヌクレオチド合成方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0713902A2 (pt) * 2006-06-27 2012-11-27 Biovitrum Ab compostos terapêuticos
US20100160351A1 (en) * 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
WO2010071865A1 (en) 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
WO2011032175A1 (en) 2009-09-14 2011-03-17 Nuon Therapeutics, Inc. Combination formulations of tranilast and allopurinol and methods related thereto
US20150038445A1 (en) * 2012-02-11 2015-02-05 Academia Sinica Methods and compositions for treating pain

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE269870T1 (de) * 1989-10-24 2004-07-15 Isis Pharmaceuticals Inc 2'-modifizierte oligonukleotide
EP0601322A3 (en) * 1992-10-27 1994-10-12 Nippon Zoki Pharmaceutical Co Adenosine deaminase inhibitor.
US5877180A (en) * 1994-07-11 1999-03-02 University Of Virginia Patent Foundation Method for treating inflammatory diseases with A2a adenosine receptor agonists
CA2361614C (en) * 1999-02-01 2008-08-26 University Of Virginia Patent Foundation Compositions for treating inflammatory response
GB0228723D0 (en) * 2002-12-09 2003-01-15 Cambridge Biotechnology Ltd Treatment of pain
GB0305150D0 (en) 2003-03-07 2003-04-09 Cambridge Biotechnology Ltd Use of therapeutic compounds
GB0305153D0 (en) * 2003-03-07 2003-04-09 Cambridge Biotechnology Ltd Identification of therapeutic compounds
GB0305149D0 (en) * 2003-03-07 2003-04-09 Cambridge Biotechnology Ltd Compounds for the treatment of pain
CA2557285A1 (en) 2004-03-05 2005-09-15 Cambridge Biotechnology Limited Adenosine receptor agonists
BRPI0713902A2 (pt) * 2006-06-27 2012-11-27 Biovitrum Ab compostos terapêuticos

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014510743A (ja) * 2011-03-31 2014-05-01 シェファー、コンスタンツェ 核酸の非ウイルスの導入のためのパーフルオロ化化合物
WO2020235658A1 (ja) * 2019-05-21 2020-11-26 株式会社四国核酸化学 オリゴヌクレオチド合成に用いるマルチフルオラスブロックマーおよびこれを用いたオリゴヌクレオチド合成方法
JPWO2020235658A1 (https=) * 2019-05-21 2020-11-26
JP7393807B2 (ja) 2019-05-21 2023-12-07 株式会社ナティアス オリゴヌクレオチド合成に用いるマルチフルオラスブロックマーおよびこれを用いたオリゴヌクレオチド合成方法
US12559516B2 (en) 2019-05-21 2026-02-24 Natias Inc. Multi-fluorous blockmer for oligonucleotide synthesis, and oligonucleotide synthesis method using the same

Also Published As

Publication number Publication date
NZ573308A (en) 2012-02-24
WO2008000745A2 (en) 2008-01-03
RU2009102531A (ru) 2010-08-10
WO2008000745A3 (en) 2008-04-17
EP2081946B1 (en) 2012-05-30
EP2081946A2 (en) 2009-07-29
CA2654375A1 (en) 2008-01-03
RU2441875C2 (ru) 2012-02-10
US7807685B2 (en) 2010-10-05
US20080076776A1 (en) 2008-03-27
AU2007263728A1 (en) 2008-01-03
CN101479289A (zh) 2009-07-08

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