JP2009541415A5 - - Google Patents

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Publication number
JP2009541415A5
JP2009541415A5 JP2009517107A JP2009517107A JP2009541415A5 JP 2009541415 A5 JP2009541415 A5 JP 2009541415A5 JP 2009517107 A JP2009517107 A JP 2009517107A JP 2009517107 A JP2009517107 A JP 2009517107A JP 2009541415 A5 JP2009541415 A5 JP 2009541415A5
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JP
Japan
Prior art keywords
alkyl
cycloalkyl
tetrazol
hetero
halo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009517107A
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English (en)
Japanese (ja)
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JP2009541415A (ja
JP5021734B2 (ja
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Publication date
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Priority claimed from PCT/EP2007/055997 external-priority patent/WO2008000645A1/en
Publication of JP2009541415A publication Critical patent/JP2009541415A/ja
Publication of JP2009541415A5 publication Critical patent/JP2009541415A5/ja
Application granted granted Critical
Publication of JP5021734B2 publication Critical patent/JP5021734B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009517107A 2006-06-29 2007-06-18 テトラゾール置換アリールアミド Active JP5021734B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81729806P 2006-06-29 2006-06-29
US60/817,298 2006-06-29
PCT/EP2007/055997 WO2008000645A1 (en) 2006-06-29 2007-06-18 Tetrazole-substituted arylamides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012134357A Division JP5456846B2 (ja) 2006-06-29 2012-06-14 テトラゾール置換アリールアミド

Publications (3)

Publication Number Publication Date
JP2009541415A JP2009541415A (ja) 2009-11-26
JP2009541415A5 true JP2009541415A5 (enExample) 2012-06-07
JP5021734B2 JP5021734B2 (ja) 2012-09-12

Family

ID=38462418

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009517107A Active JP5021734B2 (ja) 2006-06-29 2007-06-18 テトラゾール置換アリールアミド
JP2012134357A Active JP5456846B2 (ja) 2006-06-29 2012-06-14 テトラゾール置換アリールアミド

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012134357A Active JP5456846B2 (ja) 2006-06-29 2012-06-14 テトラゾール置換アリールアミド

Country Status (15)

Country Link
US (5) US7595405B2 (enExample)
EP (2) EP2592070B1 (enExample)
JP (2) JP5021734B2 (enExample)
KR (1) KR101103143B1 (enExample)
CN (2) CN103159692B (enExample)
AR (1) AR061667A1 (enExample)
AU (1) AU2007263809B2 (enExample)
BR (2) BRPI0714315B8 (enExample)
CA (1) CA2654915C (enExample)
CL (1) CL2007001887A1 (enExample)
ES (2) ES2596706T3 (enExample)
IL (2) IL195786A (enExample)
MX (1) MX2008016423A (enExample)
TW (1) TWI334414B (enExample)
WO (1) WO2008000645A1 (enExample)

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EP2215049B1 (en) * 2007-10-31 2019-06-12 Merck Sharp & Dohme Corp. P2x3, receptor antagonists for treatment of pain
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JP5318882B2 (ja) 2007-12-17 2013-10-16 エフ．ホフマン−ラ ロシュ アーゲー 新規なイミダゾール置換アリールアミド
WO2009077371A1 (en) * 2007-12-17 2009-06-25 F. Hoffmann-La Roche Ag Tetrazole-substituted arylamide derivatives and their use as p2x3 and/or p2x2/3 purinergic receptor antagonists
ES2542245T3 (es) 2007-12-17 2015-08-03 F. Hoffmann-La Roche Ag Derivados de arilamida sustituido con triazol y su utilización como antagonistas del receptor purinérgico P2x3 y/o P2x2/3
CN104058999A (zh) 2008-02-29 2014-09-24 伊沃泰克股份公司 酰胺化合物、组合物及其应用
JP5608655B2 (ja) * 2008-09-18 2014-10-15 エヴォテック アーゲー Ｐ２ｘ３受容体活性のモジュレーター
EP2358371B1 (en) * 2008-10-31 2015-02-11 Merck Sharp & Dohme Corp. P2x3, receptor antagonists for treatment of pain
CA2745290A1 (en) * 2008-12-16 2010-06-24 F. Hoffmann-La Roche Ag Thiadiazole-substituted arylamides as p2x3 and p2x2/3 antagonists
WO2010111060A1 (en) 2009-03-23 2010-09-30 Merck Sharp & Dohme Corp. P2x3, receptor antagonists for treatment of pain
AU2010229142A1 (en) 2009-03-23 2011-10-13 Merck Sharp & Dohme Corp. P2X3, receptor antagonists for treatment of pain
WO2010111059A1 (en) 2009-03-23 2010-09-30 Merck Sharp & Dohme Corp. P2x3 receptor antagonists for treatment of pain
EP2246259B1 (en) 2009-04-29 2012-12-12 Eurocopter Deutschland GmbH Rotor wing with integrated tension-torque-transmission element and method for its production
MX2011012712A (es) 2009-05-29 2012-01-30 Raqualia Pharma Inc Derivados de carboxamida sustituidos con arilo como bloqueadores del canal de calcio o sodio.
AR077033A1 (es) * 2009-06-11 2011-07-27 Hoffmann La Roche Compuestos inhibidores de las quinasas de janus y su uso en el tratamiento de enfermedades inmunologicas
ES2457543T3 (es) 2009-06-22 2014-04-28 F. Hoffmann-La Roche Ag Nuevas arilamidas de indazol como antagonistas de P2X3 y/o P2X2/3
EP2445868B1 (en) * 2009-06-22 2013-12-18 F.Hoffmann-La Roche Ag Biphenyl amides useful as p2x3 and/or p2x2/3 receptors modulators
CA2754654A1 (en) * 2009-06-22 2010-12-29 F. Hoffmann-La Roche Ag Novel oxazolone and pyrrolidinone-substituted arylamides
EP2575815A4 (en) * 2010-06-04 2013-12-25 Albany Molecular Res Inc GLYCIN TRANSPORTER 1 INHIBITORS, METHODS OF MAKING THE SAME, AND USES THEREOF
US9598409B2 (en) * 2013-01-31 2017-03-21 Neomed Institute Imidazopyridine compounds and uses thereof
AU2015359626B2 (en) 2014-12-09 2020-07-23 Bayer Aktiengesellschaft 1,3-thiazol-2-yl substituted benzamides
US10183937B2 (en) 2014-12-09 2019-01-22 Bayer Aktiengesellschaft 1,3-thiazol-2-yl substituted benzamides
WO2016169902A1 (en) * 2015-04-23 2016-10-27 F. Hoffmann-La Roche Ag Tetrazole derivatives for use in the treatment of psychiatric disorders
WO2016193235A1 (en) * 2015-06-04 2016-12-08 F. Hoffmann-La Roche Ag Imidazole derivatives
EP3359537B1 (en) * 2015-10-06 2020-03-25 H. Hoffnabb-La Roche Ag Triazole derivatives
WO2017133990A1 (en) 2016-02-02 2017-08-10 F. Hoffmann-La Roche Ag Pyrazol-pyridine derivatives as eaat3 inhibitors
TWI679197B (zh) * 2016-05-05 2019-12-11 瑞士商伊蘭科動物健康公司 雜芳基-1,2,4-三唑及雜芳基-三唑化合物
WO2017202896A1 (en) * 2016-05-27 2017-11-30 F. Hoffmann-La Roche Ag Pyrazol compounds as eaat3 inhibitors
JP7068277B2 (ja) 2016-10-14 2022-05-16 エフ．ホフマン－ラ ロシュ アーゲー Ｅａａｔ３阻害剤としてのイミダゾール化合物
TWI741040B (zh) * 2016-10-20 2021-10-01 德商拜耳作物科學公司 製備3-烷基硫基-2-氯-n-(1-烷基-1h-四唑-5-基)-4-三氟甲基苯甲醯胺之方法
RU2650780C1 (ru) 2016-12-06 2018-04-17 Общество с ограниченной ответственностью "Анальгетики будущего" Пептидный модулятор пуринергических рецепторов
KR102921974B1 (ko) 2019-05-31 2026-02-05 키에시 파르마슈티시 엣스. 피. 에이. P2x3 억제제로서 아미노 퀴나졸린 유도체
KR102923602B1 (ko) 2019-05-31 2026-02-06 키에시 파르마슈티시 엣스. 피. 에이. P2x3 억제제로서 피리도피리미딘 유도체
WO2022112491A1 (en) 2020-11-27 2022-06-02 Chiesi Farmaceutici S.P.A. (aza)quinoline 4-amines derivatives as p2x3 inhibitors
EP4251273B1 (en) 2020-11-27 2025-03-12 Chiesi Farmaceutici S.p.A. Phthalazine derivatives as p2x3 inhibitors
CA3196333A1 (en) 2020-11-27 2022-06-02 Claudio FIORELLI Amino quinazoline derivatives as p2x3 inhibitors
AR131715A1 (es) * 2023-01-30 2025-04-23 Eurofarma Laboratorios S A AMIDAS BLOQUEADORAS DE Nav 1.7 Y/O Nav 1.8, SUS PROCESOS DE OBTENCIÓN, COMPOSICIONES, USOS, MÉTODOS DE TRATAMIENTO DE LOS MISMOS Y KITS

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JP2006523701A (ja) 2003-04-18 2006-10-19 メルク　エンド　カムパニー　インコーポレーテッド ナトリウムチャネルブロッカーとしてのビアリール置換チアゾール、オキサゾール、およびイミダゾール
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