JP2009538861A5 - - Google Patents

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Publication number
JP2009538861A5
JP2009538861A5 JP2009512547A JP2009512547A JP2009538861A5 JP 2009538861 A5 JP2009538861 A5 JP 2009538861A5 JP 2009512547 A JP2009512547 A JP 2009512547A JP 2009512547 A JP2009512547 A JP 2009512547A JP 2009538861 A5 JP2009538861 A5 JP 2009538861A5
Authority
JP
Japan
Prior art keywords
compound
cyclopropylpiperazin
benzodioxol
pyridazine
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009512547A
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English (en)
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JP2009538861A (ja
JP5694661B2 (ja
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Publication date
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Priority claimed from PCT/EP2007/054940 external-priority patent/WO2007137968A1/en
Publication of JP2009538861A publication Critical patent/JP2009538861A/ja
Publication of JP2009538861A5 publication Critical patent/JP2009538861A5/ja
Application granted granted Critical
Publication of JP5694661B2 publication Critical patent/JP5694661B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Claims (4)

  1. 3-(1,3-ベンゾジオキソル-5-イル)-6-(4-シクロプロピルピペラジン-1-イル)ピリダジンの化合物又はその薬理学的に許容可能な塩。
  2. 上記化合物が3-(1,3-ベンゾジオキソル-5-イル)-6-(4-シクロプロピルピペラジン-1-イル)ピリダジンである、請求項1に記載の化合物。
  3. 上記化合物が3-(1,3-ベンゾジオキソル-5-イル)-6-(4-シクロプロピルピペラジン-1-イル)ピリダジンの塩酸塩である、請求項1に記載の化合物。
  4. 上記化合物が3-(1,3-ベンゾジオキソル-5-イル)-6-(4-シクロプロピルピペラジン-1-イル)ピリダジンジヒドロクロリドである、請求項3に記載の化合物。
JP2009512547A 2006-05-29 2007-05-22 ３−（１，３−ベンゾジオキソル−５−イル）−６−（４−シクロプロピルピペラジン−１−イル）−ピリダジンと、その塩と、その溶媒和物と、そのヒスタミンｈ３受容体アンタゴニストとしての利用法 Expired - Fee Related JP5694661B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP06114615.5 2006-05-29
EP06114615 2006-05-29
EP06120117 2006-09-05
EP06120117.4 2006-09-05
PCT/EP2007/054940 WO2007137968A1 (en) 2006-05-29 2007-05-22 3- (1, 3-benz0di0x0l-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine h3 receptor antagonist

Publications (3)

Publication Number Publication Date
JP2009538861A JP2009538861A (ja) 2009-11-12
JP2009538861A5 true JP2009538861A5 (ja) 2011-12-08
JP5694661B2 JP5694661B2 (ja) 2015-04-01

Family

ID=38458030

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009512547A Expired - Fee Related JP5694661B2 (ja) 2006-05-29 2007-05-22 ３−（１，３−ベンゾジオキソル−５−イル）−６−（４−シクロプロピルピペラジン−１−イル）−ピリダジンと、その塩と、その溶媒和物と、そのヒスタミンｈ３受容体アンタゴニストとしての利用法

Country Status (24)

Country Link
US (1) US8378097B2 (ja)
EP (2) EP2402324A1 (ja)
JP (1) JP5694661B2 (ja)
KR (1) KR20090040259A (ja)
CN (2) CN102295606A (ja)
AT (1) ATE538116T1 (ja)
AU (1) AU2007267197B2 (ja)
BR (1) BRPI0711370A2 (ja)
CA (1) CA2659570C (ja)
CY (1) CY1112455T1 (ja)
DK (1) DK2079732T3 (ja)
EA (1) EA016026B1 (ja)
ES (1) ES2375872T3 (ja)
HR (1) HRP20120227T1 (ja)
IL (1) IL194681A (ja)
MX (1) MX2008014766A (ja)
NZ (1) NZ571972A (ja)
PL (1) PL2079732T3 (ja)
PT (1) PT2079732E (ja)
RS (1) RS52234B (ja)
SG (1) SG163547A1 (ja)
SI (1) SI2079732T1 (ja)
WO (1) WO2007137968A1 (ja)
ZA (1) ZA200808730B (ja)

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US9186353B2 (en) 2009-04-27 2015-11-17 Abbvie Inc. Treatment of osteoarthritis pain
WO2012037258A1 (en) 2010-09-16 2012-03-22 Abbott Laboratories Processes for preparing 1,2-substituted cyclopropyl derivatives
WO2013151982A1 (en) 2012-04-03 2013-10-10 Arena Pharmaceuticals, Inc. Methods and compounds useful in treating pruritus, and methods for identifying such compounds
CN107428729B (zh) 2015-02-09 2021-07-16 豪夫迈·罗氏有限公司 用于治疗癌症的化合物
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WO2022053541A1 (en) * 2020-09-10 2022-03-17 Eracal Therapeutics Ltd. Compounds for use as appetite suppressant

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