JP2009537512A5 - - Google Patents
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- Publication number
- JP2009537512A5 JP2009537512A5 JP2009510906A JP2009510906A JP2009537512A5 JP 2009537512 A5 JP2009537512 A5 JP 2009537512A5 JP 2009510906 A JP2009510906 A JP 2009510906A JP 2009510906 A JP2009510906 A JP 2009510906A JP 2009537512 A5 JP2009537512 A5 JP 2009537512A5
- Authority
- JP
- Japan
- Prior art keywords
- polysaccharide
- preparation
- pharmaceutical preparation
- galactomannan
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000004676 glycans Chemical class 0.000 claims 13
- 229920001282 polysaccharide Polymers 0.000 claims 13
- 239000005017 polysaccharide Substances 0.000 claims 13
- 238000002360 preparation method Methods 0.000 claims 11
- 239000000825 pharmaceutical preparation Substances 0.000 claims 5
- OMDQUFIYNPYJFM-XKDAHURESA-N (2r,3r,4s,5r,6s)-2-(hydroxymethyl)-6-[[(2r,3s,4r,5s,6r)-4,5,6-trihydroxy-3-[(2s,3s,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@H](O)[C@H](O)O1 OMDQUFIYNPYJFM-XKDAHURESA-N 0.000 claims 3
- 229920000926 Galactomannan Polymers 0.000 claims 3
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 claims 3
- 239000007864 aqueous solution Substances 0.000 claims 3
- LUEWUZLMQUOBSB-FSKGGBMCSA-N (2s,3s,4s,5s,6r)-2-[(2r,3s,4r,5r,6s)-6-[(2r,3s,4r,5s,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5s,6r)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](OC3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-FSKGGBMCSA-N 0.000 claims 2
- 235000013912 Ceratonia siliqua Nutrition 0.000 claims 2
- 240000008886 Ceratonia siliqua Species 0.000 claims 2
- 244000303965 Cyamopsis psoralioides Species 0.000 claims 2
- 229920002581 Glucomannan Polymers 0.000 claims 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 2
- 229940046240 glucomannan Drugs 0.000 claims 2
- 230000036571 hydration Effects 0.000 claims 2
- 238000006703 hydration reaction Methods 0.000 claims 2
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 claims 1
- 229920002749 Bacterial cellulose Polymers 0.000 claims 1
- 229920002498 Beta-glucan Polymers 0.000 claims 1
- 235000017399 Caesalpinia tinctoria Nutrition 0.000 claims 1
- PTHCMJGKKRQCBF-UHFFFAOYSA-N Cellulose, microcrystalline Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC)C(CO)O1 PTHCMJGKKRQCBF-UHFFFAOYSA-N 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- 229920002558 Curdlan Polymers 0.000 claims 1
- 239000001879 Curdlan Substances 0.000 claims 1
- 235000008222 Cyamopsis psoralioides Nutrition 0.000 claims 1
- AEMOLEFTQBMNLQ-YMDCURPLSA-N D-galactopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-YMDCURPLSA-N 0.000 claims 1
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 claims 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 claims 1
- AEMOLEFTQBMNLQ-VANFPWTGSA-N D-mannopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H]1O AEMOLEFTQBMNLQ-VANFPWTGSA-N 0.000 claims 1
- 229920002148 Gellan gum Polymers 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 229920002907 Guar gum Polymers 0.000 claims 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 1
- 244000046052 Phaseolus vulgaris Species 0.000 claims 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims 1
- 241000388430 Tara Species 0.000 claims 1
- 229920001615 Tragacanth Polymers 0.000 claims 1
- 229920002000 Xyloglucan Polymers 0.000 claims 1
- 230000002378 acidificating effect Effects 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 230000032683 aging Effects 0.000 claims 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 239000000305 astragalus gummifer gum Substances 0.000 claims 1
- 239000005016 bacterial cellulose Substances 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 235000010418 carrageenan Nutrition 0.000 claims 1
- 239000000679 carrageenan Substances 0.000 claims 1
- 229920001525 carrageenan Polymers 0.000 claims 1
- 229940113118 carrageenan Drugs 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 235000010980 cellulose Nutrition 0.000 claims 1
- 229940045110 chitosan Drugs 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000003086 colorant Substances 0.000 claims 1
- 235000019316 curdlan Nutrition 0.000 claims 1
- 229940078035 curdlan Drugs 0.000 claims 1
- 230000018109 developmental process Effects 0.000 claims 1
- 208000010643 digestive system disease Diseases 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000007884 disintegrant Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 201000006549 dyspepsia Diseases 0.000 claims 1
- 210000000981 epithelium Anatomy 0.000 claims 1
- 210000003238 esophagus Anatomy 0.000 claims 1
- 239000000945 filler Substances 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000013355 food flavoring agent Nutrition 0.000 claims 1
- 235000003599 food sweetener Nutrition 0.000 claims 1
- 229930182830 galactose Natural products 0.000 claims 1
- 210000001156 gastric mucosa Anatomy 0.000 claims 1
- 208000021302 gastroesophageal reflux disease Diseases 0.000 claims 1
- 235000010492 gellan gum Nutrition 0.000 claims 1
- 239000000216 gellan gum Substances 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 229940097043 glucuronic acid Drugs 0.000 claims 1
- 239000003979 granulating agent Substances 0.000 claims 1
- 235000010417 guar gum Nutrition 0.000 claims 1
- 208000024798 heartburn Diseases 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 1
- 239000008108 microcrystalline cellulose Substances 0.000 claims 1
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 230000002028 premature Effects 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 239000003765 sweetening agent Substances 0.000 claims 1
- 239000002562 thickening agent Substances 0.000 claims 1
- 239000001917 trigonella foenum graecum l. absolute Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 229920001285 xanthan gum Polymers 0.000 claims 1
- 239000000230 xanthan gum Substances 0.000 claims 1
- 235000010493 xanthan gum Nutrition 0.000 claims 1
- 229940082509 xanthan gum Drugs 0.000 claims 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06076056A EP1859786A1 (en) | 2006-05-16 | 2006-05-16 | A method to reduce the symptoms of heartburn and gastro-oesophageal reflux disease (GERD) by specific polysaccharides |
| US80631306P | 2006-06-30 | 2006-06-30 | |
| PCT/NL2007/050224 WO2007133082A1 (en) | 2006-05-16 | 2007-05-16 | A method to reduce the symptoms of heartburn and gastro-oesophageal reflux disease (gerd) by specific polysaccharides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009537512A JP2009537512A (ja) | 2009-10-29 |
| JP2009537512A5 true JP2009537512A5 (https=) | 2010-07-08 |
Family
ID=37806824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009510906A Pending JP2009537512A (ja) | 2006-05-16 | 2007-05-16 | 特定の多糖類により胸焼け及び胃食道逆流病の症状を減少する方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20090252792A1 (https=) |
| EP (2) | EP1859786A1 (https=) |
| JP (1) | JP2009537512A (https=) |
| KR (1) | KR20090048393A (https=) |
| AT (1) | ATE514415T1 (https=) |
| AU (1) | AU2007250624B2 (https=) |
| RU (1) | RU2432167C2 (https=) |
| TW (1) | TWI402074B (https=) |
| WO (1) | WO2007133082A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090148530A1 (en) * | 2007-12-08 | 2009-06-11 | Jamie Koufman | Method for prevention and treatment of reflux injury in the aerodigestive tract and laryngopharynx caused by pepsin |
| EP2346351B1 (en) | 2008-09-22 | 2019-07-03 | Rubicon Research Private Limited | Compositions exhibiting delayed transit through the gastrointestinal tract |
| DK2564840T3 (en) | 2010-04-26 | 2015-03-02 | De Santos Angel Manuel Gago | Compositions for symptomatic relief of abdominal pain or gastroesophageal reflux |
| ITRM20120041A1 (it) * | 2012-02-08 | 2013-08-09 | Dicofarm Spa | "prodotto a base di glucomannano e chitosano utile per il trattamento del reflusso gastroesofageo" |
| ITRM20120084A1 (it) * | 2012-03-07 | 2013-09-08 | Aboca Spa Societa Agricola | Miscela prebiotica. |
| EP2827839B1 (en) | 2012-03-20 | 2019-02-27 | Particle Dynamics International, LLC | Gelling agent-based dosage form |
| ITMI20130960A1 (it) * | 2013-06-11 | 2014-12-12 | Novintethical Pharma Sagl | Composizioni a base di xiloglucano per il trattamento di disturbi gastrointestinali |
| IT201700091733A1 (it) * | 2017-08-08 | 2019-02-08 | Neilos S R L | Composizione per somministrazione orale per uso nel trattamento terapeutico o preventivo dei disturbi o malattia da reflusso gastroesofageo |
| JP2019064980A (ja) * | 2017-10-03 | 2019-04-25 | 小林製薬株式会社 | 逆流性食道炎改善剤 |
| AU2019312160B2 (en) | 2018-07-23 | 2024-02-22 | Nutragenom, Llc | Composition and methods for generating and sustaining molecular hydrogen (H2) in aqueous systems |
| CN111227156A (zh) * | 2020-01-20 | 2020-06-05 | 陕西科技大学 | 一种抑制反酸的固体饮料及其制备方法 |
| WO2022240224A1 (ko) * | 2021-05-14 | 2022-11-17 | 한국식품연구원 | 젤란검을 유효성분으로 하는 장내 균총 개선용 조성물 및 이를 포함하는 대사성 질환 개선, 예방 또는 치료용 조성물 |
| TWI777673B (zh) * | 2021-07-16 | 2022-09-11 | 陳昭誠 | 由β-1-4-葡聚醣形成之纖維於製備用於治療或預防胃食道逆流之組成物之用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3152319C2 (de) * | 1980-09-03 | 1986-05-07 | Kyosei Pharmaceutical Co., Ltd., Hokkaido | Verwendung einer Lösung eines Salzes der Alginsäure zur Behandlung von Strahlenschäden und Ulcera |
| IL108583A (en) * | 1994-02-07 | 1997-06-10 | Yissum Res Dev Co | Galactomannan emulsions and comestible products containing the same |
| GB9708773D0 (en) * | 1997-04-30 | 1997-06-25 | Reckitt & Colmann Prod Ltd | Organic compositions |
| CA2206157C (en) * | 1997-05-26 | 2000-06-13 | Cheng, Peter | Method of extraction of commercially valuable fractions of fenugreek |
| GB9910212D0 (en) * | 1999-05-05 | 1999-06-30 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
| GB0005743D0 (en) * | 2000-03-10 | 2000-05-03 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions including alginates |
| GB2384986B (en) * | 2002-02-12 | 2004-01-07 | Reckitt Benckiser Healthcare | Compositions for the treatment of disorders of the upper gastrointestinal tract |
| CN1780880B (zh) * | 2003-04-25 | 2010-04-28 | 雷克特本克斯尔保健(英国)有限公司 | 可增稠的组合物 |
| ATE390142T1 (de) * | 2003-05-14 | 2008-04-15 | Indus Biotech Pvt Ltd | Synergistische zusammensetzung zur behandlung von diabetes mellitus |
-
2006
- 2006-05-16 EP EP06076056A patent/EP1859786A1/en not_active Withdrawn
-
2007
- 2007-05-14 TW TW096117078A patent/TWI402074B/zh not_active IP Right Cessation
- 2007-05-16 AU AU2007250624A patent/AU2007250624B2/en not_active Ceased
- 2007-05-16 KR KR1020087030557A patent/KR20090048393A/ko not_active Ceased
- 2007-05-16 AT AT07747448T patent/ATE514415T1/de not_active IP Right Cessation
- 2007-05-16 RU RU2008149527/15A patent/RU2432167C2/ru active
- 2007-05-16 JP JP2009510906A patent/JP2009537512A/ja active Pending
- 2007-05-16 US US12/300,632 patent/US20090252792A1/en not_active Abandoned
- 2007-05-16 EP EP07747448A patent/EP2026763B1/en active Active
- 2007-05-16 WO PCT/NL2007/050224 patent/WO2007133082A1/en not_active Ceased
-
2012
- 2012-03-15 US US13/421,741 patent/US20120231078A1/en not_active Abandoned
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