JP2009530613A5 - - Google Patents
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- Publication number
- JP2009530613A5 JP2009530613A5 JP2009500495A JP2009500495A JP2009530613A5 JP 2009530613 A5 JP2009530613 A5 JP 2009530613A5 JP 2009500495 A JP2009500495 A JP 2009500495A JP 2009500495 A JP2009500495 A JP 2009500495A JP 2009530613 A5 JP2009530613 A5 JP 2009530613A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- gelsolin
- level
- composition
- multiple sclerosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004878 Gelsolin Human genes 0.000 claims 20
- 108090001064 Gelsolin Proteins 0.000 claims 20
- 201000006417 multiple sclerosis Diseases 0.000 claims 13
- 210000001124 body fluid Anatomy 0.000 claims 5
- 239000010839 body fluid Substances 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 208000012902 Nervous system disease Diseases 0.000 claims 4
- 208000025966 Neurological disease Diseases 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78250906P | 2006-03-15 | 2006-03-15 | |
| PCT/US2007/006581 WO2007106577A2 (en) | 2006-03-15 | 2007-03-14 | Gelsolin in the treatment and diagnosis of neurological disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011271607A Division JP6203995B2 (ja) | 2006-03-15 | 2011-12-12 | 多発性硬化症を治療するため、および神経疾患を診断するための、ゲルゾリンの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009530613A JP2009530613A (ja) | 2009-08-27 |
| JP2009530613A5 true JP2009530613A5 (cg-RX-API-DMAC10.html) | 2010-05-06 |
Family
ID=38510104
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009500495A Pending JP2009530613A (ja) | 2006-03-15 | 2007-03-14 | 多発性硬化症を治療するため、および神経疾患を診断するための、ゲルゾリンの使用 |
| JP2011271607A Active JP6203995B2 (ja) | 2006-03-15 | 2011-12-12 | 多発性硬化症を治療するため、および神経疾患を診断するための、ゲルゾリンの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011271607A Active JP6203995B2 (ja) | 2006-03-15 | 2011-12-12 | 多発性硬化症を治療するため、および神経疾患を診断するための、ゲルゾリンの使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8440622B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2002258B1 (cg-RX-API-DMAC10.html) |
| JP (2) | JP2009530613A (cg-RX-API-DMAC10.html) |
| CN (1) | CN101460843B (cg-RX-API-DMAC10.html) |
| CA (1) | CA2680333C (cg-RX-API-DMAC10.html) |
| DK (1) | DK2002258T3 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2651619T3 (cg-RX-API-DMAC10.html) |
| HU (1) | HUE035980T2 (cg-RX-API-DMAC10.html) |
| PL (1) | PL2002258T3 (cg-RX-API-DMAC10.html) |
| PT (1) | PT2002258T (cg-RX-API-DMAC10.html) |
| WO (1) | WO2007106577A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070238655A1 (en) * | 2003-11-12 | 2007-10-11 | The Trustees Of The University Of Pennsylvania | Methods of Using Gelsolin to Treat or Prevent Bacterial Sepsis |
| US9408891B2 (en) | 2003-11-12 | 2016-08-09 | The Trustees Of The University Of Pennsylvania | Methods of using gelsolin to treat or prevent bacterial sepsis |
| CN1980694B (zh) * | 2004-05-12 | 2012-09-26 | 布赖汉姆妇女医院有限公司 | 凝溶胶蛋白治疗感染的用途 |
| JP4348631B2 (ja) * | 2005-03-29 | 2009-10-21 | セイコーエプソン株式会社 | 半導体素子の製造方法 |
| US8198094B2 (en) | 2006-03-15 | 2012-06-12 | The Brigham And Women's Hospital, Inc. | Methods of using gelsolin levels to characterize a subject's risk of developing rheumatoid arthritis |
| EP2708603B1 (en) | 2008-01-25 | 2017-04-19 | The General Hospital Corporation | Diagnostic and therapeutic uses of gelsolin in renal failure |
| WO2009124226A2 (en) * | 2008-04-03 | 2009-10-08 | The Trustees Of The University Of Pennsylvania | Gelsolin uses in neurological disorders |
| USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| DE102010026500A1 (de) * | 2010-07-07 | 2012-01-12 | Arthrogen Gmbh | Verfahren zur Herstellung von autologen Proteinen |
| WO2012081701A1 (ja) * | 2010-12-16 | 2012-06-21 | 独立行政法人産業技術総合研究所 | 髄液型糖タンパク質の富化及び分離方法、並びにその方法を用いた中枢神経系疾患用マーカーの探索方法及び中枢神経系疾患用マーカー |
| KR101416954B1 (ko) * | 2012-09-12 | 2014-07-16 | 한양대학교 산학협력단 | 조혈세포 분화 유도 방법 |
| US10161006B2 (en) | 2014-03-11 | 2018-12-25 | Iucf-Hyu (Industry-University Cooperation Foundation Hanyang University) | Diagnosis of hematologic diseases |
| FR3036188B1 (fr) * | 2015-05-12 | 2019-06-07 | Biomerieux | Prediction du risque de developper, pour des patients admis en service de reanimation, une infection disseminee |
| JP6947449B2 (ja) * | 2016-06-29 | 2021-10-13 | 学校法人自治医科大学 | バイオマーカー、診断用組成物、及び診断用キット |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| AU2017319728B2 (en) | 2016-08-31 | 2024-09-05 | Mapi Pharma Ltd | Depot systems comprising glatiramer acetate |
| IL316573A (en) | 2017-03-26 | 2024-12-01 | Mapi Pharma Ltd | Storage systems containing glatiramer acetate for the treatment of multiple sclerosis |
| TWI697499B (zh) * | 2018-03-05 | 2020-07-01 | 中央研究院 | 用以診斷周邊神經病變的方法及套組 |
| WO2020263484A1 (en) * | 2019-06-28 | 2020-12-30 | Mayo Foundation For Medical Education And Research | Methods and materials for treating neuromyelitis optica spectrum diseases |
| CN116615216A (zh) * | 2020-09-23 | 2023-08-18 | 生物保护医疗公司 | 用于鉴定和治疗微粒相关疾病和病症的组合物和方法 |
| CA3196026A1 (en) * | 2020-09-23 | 2022-03-31 | Bioaegis Therapeutics Inc. | Compositions and methods for identifying and treating microparticle-associated diseases and conditions |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US627353A (en) * | 1899-06-20 | Cis robinson | ||
| US5071773A (en) * | 1986-10-24 | 1991-12-10 | The Salk Institute For Biological Studies | Hormone receptor-related bioassays |
| CA2016227A1 (en) * | 1989-05-18 | 1990-11-18 | Xandra O. Breakefield | Genetic diagnosis of torsion dystonia |
| ES2124702T3 (es) | 1990-04-11 | 1999-02-16 | Brigham & Womens Hospital | Usos terapeuticos de compuestos que se unen a actina. |
| US5464817A (en) | 1990-04-11 | 1995-11-07 | Brigham And Women's Hospital | Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I |
| CA2063593A1 (en) | 1990-05-04 | 1991-11-05 | Biogen, Inc. | Multimeric gelsolin fusion constructs |
| US5571511A (en) * | 1990-10-22 | 1996-11-05 | The U.S. Government | Broadly reactive opsonic antibodies that react with common staphylococcal antigens |
| JP3507486B2 (ja) | 1991-03-15 | 2004-03-15 | アムジエン・インコーポレーテツド | 顆粒球コロニー刺激因子の肺内投与 |
| US5360350A (en) * | 1991-08-23 | 1994-11-01 | The Whitaker Corporation | Sealant compositions and sealed electrical connectors |
| US5691160A (en) | 1992-08-14 | 1997-11-25 | Biogen, Inc. | Effects of actin filaments of fibrin clot structure and lysis |
| US5593964A (en) | 1993-10-07 | 1997-01-14 | The George Washington University Medical Center | Method of treating septic shock by preventing actin polymerization |
| JP3914272B2 (ja) | 1993-12-28 | 2007-05-16 | 中外製薬株式会社 | アドゼベリンをコードする遺伝子 |
| US5451569A (en) | 1994-04-19 | 1995-09-19 | Hong Kong University Of Science And Technology R & D Corporation Limited | Pulmonary drug delivery system |
| US5846743A (en) * | 1995-02-22 | 1998-12-08 | Brigham And Women's Hospital, Inc. | Polyphoshoinositide binding peptides for intracellular drug delivery |
| US5804427A (en) * | 1995-05-19 | 1998-09-08 | University Of Massachusetts | Cytokine-, stress-, and oncoprotein-activated human protein kinase kinases |
| US5925529A (en) * | 1995-06-07 | 1999-07-20 | The Regents Of The University Of California | Method for discovery of peptide agonists |
| US5569588A (en) * | 1995-08-09 | 1996-10-29 | The Regents Of The University Of California | Methods for drug screening |
| US5750353A (en) * | 1995-12-11 | 1998-05-12 | New England Medical Center Hospitals, Inc. | Assay for non-peptide agonists to peptide hormone receptors |
| DK0941108T3 (da) * | 1996-12-04 | 2002-11-18 | Renovo Ltd | Sårheling og behandling af fibrose |
| WO1998043630A1 (en) * | 1997-04-02 | 1998-10-08 | Brigham And Women's Hospital, Inc. | Means of ascertaining an individual's risk profile for atherosclerotic disease |
| AU3395900A (en) | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| US6409599B1 (en) | 1999-07-19 | 2002-06-25 | Ham On Rye Technologies, Inc. | Interactive virtual reality performance theater entertainment system |
| WO2002059604A2 (en) | 2001-01-26 | 2002-08-01 | Oxford Glycosciences (Uk) Ltd | Diagnosis and treatment of multiple sclerosis |
| EP1249244A1 (en) * | 2001-04-13 | 2002-10-16 | Universiteit Gent | Therapeutic compositions for the treatment of a disease modulated by the G-actin / F-actin equilibrium, especially a respiratory tract disease |
| EP2266595A3 (en) | 2002-02-06 | 2011-07-06 | Regenerx Biopharmaceuticals, Inc. | Treatment of infections and other disorders |
| WO2003088811A2 (en) | 2002-04-16 | 2003-10-30 | The Brigham And Women's Hospital, Inc. | Gelsolin as a prognostic marker of artherosclerotic diseases |
| WO2004001421A2 (en) * | 2002-06-21 | 2003-12-31 | Innogenetics N.V. | Method for the diagnosis and differential diagnosis of neurological diseases |
| WO2004023973A2 (en) | 2002-09-12 | 2004-03-25 | Incyte Corporation | Molecules for diagnostics and therapeutics |
| US20050048574A1 (en) | 2003-03-14 | 2005-03-03 | Kantor Aaron B. | Biomarkers for diagnosing rheumatoid arthritis |
| US20070238655A1 (en) * | 2003-11-12 | 2007-10-11 | The Trustees Of The University Of Pennsylvania | Methods of Using Gelsolin to Treat or Prevent Bacterial Sepsis |
| US9408891B2 (en) * | 2003-11-12 | 2016-08-09 | The Trustees Of The University Of Pennsylvania | Methods of using gelsolin to treat or prevent bacterial sepsis |
| CN1980694B (zh) * | 2004-05-12 | 2012-09-26 | 布赖汉姆妇女医院有限公司 | 凝溶胶蛋白治疗感染的用途 |
| SG183012A1 (en) * | 2004-06-04 | 2012-08-30 | Genentech Inc | Method for treating multiple sclerosis |
| DK1929297T3 (da) * | 2005-09-29 | 2013-03-04 | Caprion Proteomics Usa Llc | Biomarkører for dissemineret sklerose og fremgangsmåder til anvendelse heraf |
| US8198094B2 (en) * | 2006-03-15 | 2012-06-12 | The Brigham And Women's Hospital, Inc. | Methods of using gelsolin levels to characterize a subject's risk of developing rheumatoid arthritis |
| EP2708603B1 (en) * | 2008-01-25 | 2017-04-19 | The General Hospital Corporation | Diagnostic and therapeutic uses of gelsolin in renal failure |
-
2007
- 2007-03-14 JP JP2009500495A patent/JP2009530613A/ja active Pending
- 2007-03-14 PT PT77532265T patent/PT2002258T/pt unknown
- 2007-03-14 EP EP07753226.5A patent/EP2002258B1/en active Active
- 2007-03-14 US US12/225,132 patent/US8440622B2/en active Active
- 2007-03-14 PL PL07753226T patent/PL2002258T3/pl unknown
- 2007-03-14 WO PCT/US2007/006581 patent/WO2007106577A2/en not_active Ceased
- 2007-03-14 CA CA2680333A patent/CA2680333C/en active Active
- 2007-03-14 ES ES07753226.5T patent/ES2651619T3/es active Active
- 2007-03-14 HU HUE07753226A patent/HUE035980T2/hu unknown
- 2007-03-14 DK DK07753226.5T patent/DK2002258T3/en active
- 2007-03-14 CN CN200780017675.5A patent/CN101460843B/zh active Active
-
2011
- 2011-12-12 JP JP2011271607A patent/JP6203995B2/ja active Active
-
2013
- 2013-04-12 US US13/861,578 patent/US20130230455A1/en not_active Abandoned
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