JP2009530423A5 - - Google Patents
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- Publication number
- JP2009530423A5 JP2009530423A5 JP2009501727A JP2009501727A JP2009530423A5 JP 2009530423 A5 JP2009530423 A5 JP 2009530423A5 JP 2009501727 A JP2009501727 A JP 2009501727A JP 2009501727 A JP2009501727 A JP 2009501727A JP 2009530423 A5 JP2009530423 A5 JP 2009530423A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- antibody
- chain variable
- variable region
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 208000024827 Alzheimer disease Diseases 0.000 claims 9
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 8
- 239000012634 fragment Substances 0.000 claims 8
- 210000004556 brain Anatomy 0.000 claims 5
- 230000004770 neurodegeneration Effects 0.000 claims 5
- 208000037259 Amyloid Plaque Diseases 0.000 claims 4
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 4
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 4
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 4
- 238000009825 accumulation Methods 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 230000006999 cognitive decline Effects 0.000 claims 4
- 208000010877 cognitive disease Diseases 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 208000035475 disorder Diseases 0.000 claims 4
- 230000002401 inhibitory effect Effects 0.000 claims 4
- 230000003941 amyloidogenesis Effects 0.000 claims 3
- 230000001939 inductive effect Effects 0.000 claims 3
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 230000002195 synergetic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78457506P | 2006-03-21 | 2006-03-21 | |
| US89530307P | 2007-03-16 | 2007-03-16 | |
| PCT/US2007/064571 WO2007109749A2 (en) | 2006-03-21 | 2007-03-21 | Methods for preventing and treating amyloidogenic diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009530423A JP2009530423A (ja) | 2009-08-27 |
| JP2009530423A5 true JP2009530423A5 (enExample) | 2011-05-26 |
Family
ID=38523302
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009501725A Pending JP2009529920A (ja) | 2006-03-21 | 2007-03-21 | Rageの拮抗作用のための方法および組成物 |
| JP2009501727A Withdrawn JP2009530423A (ja) | 2006-03-21 | 2007-03-21 | アミロイド生成性疾患を予防および処置するための方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009501725A Pending JP2009529920A (ja) | 2006-03-21 | 2007-03-21 | Rageの拮抗作用のための方法および組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20070286858A1 (enExample) |
| EP (2) | EP2004694A2 (enExample) |
| JP (2) | JP2009529920A (enExample) |
| KR (2) | KR20080110833A (enExample) |
| AU (2) | AU2007226863A1 (enExample) |
| BR (2) | BRPI0708998A2 (enExample) |
| CA (2) | CA2646643A1 (enExample) |
| CR (2) | CR10297A (enExample) |
| EC (1) | ECSP088750A (enExample) |
| MX (2) | MX2008011933A (enExample) |
| NO (2) | NO20083720L (enExample) |
| RU (2) | RU2008134135A (enExample) |
| WO (2) | WO2007109747A2 (enExample) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136311A (en) | 1996-05-06 | 2000-10-24 | Cornell Research Foundation, Inc. | Treatment and diagnosis of cancer |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| WO2005122712A2 (en) * | 2003-06-11 | 2005-12-29 | Socratech L.L.C. | Soluble low-density lipoprotein receptor related protein binds directly to alzheimer’s amyloid-beta peptide |
| SG10201706600VA (en) | 2005-11-30 | 2017-09-28 | Abbvie Inc | Monoclonal antibodies and uses thereof |
| KR20080090408A (ko) | 2005-11-30 | 2008-10-08 | 아보트 러보러터리즈 | 항-Aβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법 |
| WO2007109321A2 (en) | 2006-03-20 | 2007-09-27 | The Regents Of The University Of California | Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting |
| AU2007226863A1 (en) * | 2006-03-21 | 2007-09-27 | Wyeth | Methods for preventing and treating amyloidogenic diseases |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| WO2008104386A2 (en) | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
| US8841421B2 (en) * | 2007-04-26 | 2014-09-23 | Active Biotech, Ab | S100A9 interaction screening method |
| EP1986009A1 (en) * | 2007-04-26 | 2008-10-29 | Active Biotech AB | Screening method |
| CA2698343C (en) | 2007-09-04 | 2018-06-12 | The Regents Of The University Of California | High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection |
| US20110014624A1 (en) * | 2008-03-12 | 2011-01-20 | Wyeth Llc | Methods For Identifying Cells Suitable For Large-Scale Production of Recombinant Proteins |
| CN102076355B (zh) | 2008-04-29 | 2014-05-07 | Abbvie公司 | 双重可变结构域免疫球蛋白及其用途 |
| KR101603917B1 (ko) * | 2008-05-09 | 2016-03-17 | 애브비 인코포레이티드 | 최종 당화 산물의 수용체(rage)에 대한 항체 및 이의 용도 |
| JP2009276245A (ja) * | 2008-05-15 | 2009-11-26 | Shiseido Co Ltd | 持続性皮膚炎症性疾患の改善剤をスクリーニングする方法及びその改善剤 |
| AU2009256246B2 (en) * | 2008-06-03 | 2013-07-18 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
| SG191639A1 (en) | 2008-06-03 | 2013-07-31 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| AU2009268585C1 (en) | 2008-07-08 | 2014-10-02 | Abbvie Inc. | Prostaglandin E2 dual variable domain immunoglobulins and uses thereof |
| EP2313436B1 (en) * | 2008-07-22 | 2014-11-26 | Ablynx N.V. | Amino acid sequences directed against multitarget scavenger receptors and polypeptides |
| US20100143349A1 (en) * | 2008-08-12 | 2010-06-10 | Wyeth | Humanized anti-rage antibody |
| EP2364359A2 (en) | 2008-09-26 | 2011-09-14 | Wyeth LLC | Compatible display vector systems |
| EP2356231A2 (en) * | 2008-09-26 | 2011-08-17 | Wyeth LLC | Compatible display vector systems |
| KR20180026561A (ko) * | 2009-01-19 | 2018-03-12 | 비오메리으 | 환자가 병원감염에 걸릴 가능성을 결정하고 패혈 증후군 진행의 예후를 결정하는 방법 |
| EP2398504B1 (en) | 2009-02-17 | 2018-11-28 | Cornell Research Foundation, Inc. | Methods and kits for diagnosis of cancer and prediction of therapeutic value |
| EP2421892A1 (en) * | 2009-04-20 | 2012-02-29 | Pfizer Inc. | Control of protein glycosylation and compositions and methods relating thereto |
| TW201119673A (en) * | 2009-09-01 | 2011-06-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| EP2319871A1 (en) * | 2009-11-05 | 2011-05-11 | Sanofi-aventis | Polypeptides for binding to the "receptor for advanced glycation endproducts" as well as compositions and methods involving the same |
| AU2010305374A1 (en) * | 2009-10-09 | 2012-05-03 | Sanofi | Polypeptides for binding to the "receptor for advanced glycation endproducts" as well as compositions and methods involving the same |
| EP2308896A1 (en) * | 2009-10-09 | 2011-04-13 | Sanofi-aventis | Polypeptides for binding to the "receptor for advanced glycation endproducts" as well as compositions and methods involving the same |
| UY32948A (es) | 2009-10-15 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| TW201121568A (en) | 2009-10-31 | 2011-07-01 | Abbott Lab | Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof |
| US8772459B2 (en) | 2009-12-02 | 2014-07-08 | Imaginab, Inc. | J591 minibodies and Cys-diabodies for targeting human prostate specific membrane antigen (PSMA) and methods for their use |
| EP2558494B1 (en) | 2010-04-15 | 2018-05-23 | AbbVie Inc. | Amyloid-beta binding proteins |
| TW201206473A (en) | 2010-08-03 | 2012-02-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| US9062101B2 (en) | 2010-08-14 | 2015-06-23 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| CN103260639A (zh) | 2010-08-26 | 2013-08-21 | Abbvie公司 | 双重可变结构域免疫球蛋白及其用途 |
| DK2663579T3 (en) | 2011-01-14 | 2017-07-31 | Univ California | THERAPEUTIC ANTIBODIES AGAINST ROR-1 PROTEIN AND PROCEDURES FOR USE THEREOF |
| EP2667766A4 (en) * | 2011-01-25 | 2016-08-17 | Oncofluor Inc | PROCESS FOR COMBINED IMAGING AND TREATMENT OF ORGANS AND WOVEN FABRICS |
| CN103460045B (zh) | 2011-04-05 | 2016-01-20 | 奥林巴斯株式会社 | 胰脏检查方法及胰脏检查试剂盒 |
| US9244074B2 (en) | 2011-06-07 | 2016-01-26 | University Of Hawaii | Biomarker of asbestos exposure and mesothelioma |
| WO2012170742A2 (en) | 2011-06-07 | 2012-12-13 | University Of Hawaii | Treatment and prevention of cancer with hmgb1 antagonists |
| WO2013102042A2 (en) | 2011-12-30 | 2013-07-04 | Abbvie Inc. | Dual specific binding proteins directed against il-13 and/or il-17 |
| KR101477130B1 (ko) | 2012-01-11 | 2015-01-06 | 연세대학교 산학협력단 | 용해성 rage를 유효성분으로 포함하는 심근염의 예방 또는 치료용 약제학적 조성물 |
| US9803005B2 (en) | 2012-05-24 | 2017-10-31 | Alexion Pharmaceuticals, Inc. | Humaneered anti-factor B antibody |
| HK1212359A1 (en) | 2012-11-01 | 2016-06-10 | Abbvie Inc. | Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof |
| JP2016522793A (ja) | 2013-03-15 | 2016-08-04 | アッヴィ・インコーポレイテッド | IL−1βおよび/またはIL−17に対して指向された二重特異的結合タンパク質 |
| CA3222465A1 (en) | 2013-08-30 | 2015-03-05 | Immunogen, Inc. | Antibodies and assays for detection of folate receptor 1 |
| HUE071397T2 (hu) * | 2013-10-31 | 2025-08-28 | Amgen Inc | Monenzin alkalmazása rekombináns fehérjék glikozilációjának szabályozására |
| US10191033B2 (en) | 2013-12-05 | 2019-01-29 | The Broad Institute, Inc. | Biomarkers for detecting pre-cachexia or cachexia and methods of treatment thereof |
| US10023651B2 (en) | 2014-04-18 | 2018-07-17 | The Research Foundation For The State University Of New York | Humanized anti-TF-antigen antibodies |
| EP3797793A1 (en) | 2014-04-18 | 2021-03-31 | The Research Foundation of the State University of New York at Buffalo | Humanized anti-tf-antigen antibodies |
| WO2016061532A1 (en) * | 2014-10-16 | 2016-04-21 | The Broad Institute Inc. | Compositions and methods for identifying and treating cachexia or pre-cachexia |
| JP6679096B2 (ja) * | 2014-10-21 | 2020-04-15 | 学校法人 久留米大学 | Rageアプタマーおよびその用途 |
| WO2016094881A2 (en) | 2014-12-11 | 2016-06-16 | Abbvie Inc. | Lrp-8 binding proteins |
| EP3307781B8 (en) | 2015-06-10 | 2020-12-02 | The Broad Institute, Inc. | Antibodies, compounds and screens for identifying and treating cachexia or pre-cachexia |
| CN107709366B (zh) * | 2015-06-10 | 2021-10-26 | 干细胞技术公司 | 用于双功能免疫复合物的原位形成的方法 |
| WO2016201319A1 (en) * | 2015-06-10 | 2016-12-15 | The Broad Institute Inc. | Antibodies, compounds and screens for identifying and treating cachexia or pre-cachexia |
| TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
| ES3020458T3 (en) | 2015-08-07 | 2025-05-22 | Imaginab Inc | Antigen binding constructs to target molecules |
| CN116440279A (zh) | 2015-09-17 | 2023-07-18 | 伊缪诺金公司 | 包含抗folr1免疫缀合物的治疗组合 |
| WO2017106196A1 (en) | 2015-12-14 | 2017-06-22 | The Broad Institute, Inc. | Compositions and methods for treating cardiac dysfunction |
| JP7010491B2 (ja) * | 2016-04-11 | 2022-01-26 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク | ヒト化抗rage抗体 |
| US11266745B2 (en) | 2017-02-08 | 2022-03-08 | Imaginab, Inc. | Extension sequences for diabodies |
| KR20190134997A (ko) | 2017-02-17 | 2019-12-05 | 데날리 테라퓨틱스 인크. | 항-tau 항체 및 이의 사용 방법 |
| WO2020019095A1 (es) * | 2018-07-26 | 2020-01-30 | Universidad Católica Del Maule | Proteína rage (receptor de productos finales de glicacíon avanzada) como biomarcador de sensibilidad tumoral y evaluacion de terapia radiologica y radiomimética |
| US11621087B2 (en) * | 2019-09-24 | 2023-04-04 | International Business Machines Corporation | Machine learning for amyloid and tau pathology prediction |
| CA3239080A1 (en) * | 2021-11-18 | 2023-05-25 | Salvarx Llc | Antibodies to receptor of advanced glycation end products (rage) and uses thereof |
| WO2024077122A1 (en) * | 2022-10-05 | 2024-04-11 | The Regents Of The University Of California | Multipurpose, multi-functionalized lipid coated beads and methods of production |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4196265A (en) * | 1977-06-15 | 1980-04-01 | The Wistar Institute | Method of producing antibodies |
| US6054561A (en) * | 1984-02-08 | 2000-04-25 | Chiron Corporation | Antigen-binding sites of antibody molecules specific for cancer antigens |
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5260203A (en) * | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US6893625B1 (en) * | 1986-10-27 | 2005-05-17 | Royalty Pharma Finance Trust | Chimeric antibody with specificity to human B cell surface antigen |
| US5041138A (en) * | 1986-11-20 | 1991-08-20 | Massachusetts Institute Of Technology | Neomorphogenesis of cartilage in vivo from cell culture |
| AU600575B2 (en) * | 1987-03-18 | 1990-08-16 | Sb2, Inc. | Altered antibodies |
| US5132405A (en) * | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5091513A (en) * | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5892019A (en) * | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| KR0162259B1 (ko) * | 1989-12-05 | 1998-12-01 | 아미 펙터 | 감염성 병변 및 염증성 병변을 검출 및 치료하기 위한 키메라 항체 |
| US6300129B1 (en) * | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
| GB9115364D0 (en) * | 1991-07-16 | 1991-08-28 | Wellcome Found | Antibody |
| US5777079A (en) * | 1994-11-10 | 1998-07-07 | The Regents Of The University Of California | Modified green fluorescent proteins |
| US5625048A (en) * | 1994-11-10 | 1997-04-29 | The Regents Of The University Of California | Modified green fluorescent proteins |
| US5871902A (en) * | 1994-12-09 | 1999-02-16 | The Gene Pool, Inc. | Sequence-specific detection of nucleic acid hybrids using a DNA-binding molecule or assembly capable of discriminating perfect hybrids from non-perfect hybrids |
| US5739277A (en) * | 1995-04-14 | 1998-04-14 | Genentech Inc. | Altered polypeptides with increased half-life |
| WO1997026913A1 (en) * | 1996-01-26 | 1997-07-31 | The Trustees Of Columbia University In The City Of New York | A POLYPEPTIDE FROM LUNG EXTRACT WHICH BINDS AMYLOID-β PEPTIDE |
| US5864018A (en) * | 1996-04-16 | 1999-01-26 | Schering Aktiengesellschaft | Antibodies to advanced glycosylation end-product receptor polypeptides and uses therefor |
| US6124128A (en) * | 1996-08-16 | 2000-09-26 | The Regents Of The University Of California | Long wavelength engineered fluorescent proteins |
| ATE364718T1 (de) * | 1997-04-01 | 2007-07-15 | Solexa Ltd | Verfahren zur vervielfältigung von nukleinsäure |
| CA2382095A1 (en) * | 1999-08-13 | 2001-02-22 | The Trustees Of Columbia University In The City Of New York | Methods of inhibiting binding of .beta.-sheet fibril to rage and consequences thereof |
| CA2634294A1 (en) * | 2000-08-03 | 2002-02-14 | Therapeutic Human Polyclonals, Inc. | Production of humanized antibodies in transgenic animals |
| US7829084B2 (en) * | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
| US20030133939A1 (en) * | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
| US7754208B2 (en) * | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| JP4171228B2 (ja) * | 2001-03-19 | 2008-10-22 | 第一ファインケミカル株式会社 | 可溶型rage測定法 |
| US20040058445A1 (en) * | 2001-04-26 | 2004-03-25 | Ledbetter Jeffrey Alan | Activation of tumor-reactive lymphocytes via antibodies or genes recognizing CD3 or 4-1BB |
| US7321026B2 (en) * | 2001-06-27 | 2008-01-22 | Skytech Technology Limited | Framework-patched immunoglobulins |
| CN1774445A (zh) * | 2002-08-16 | 2006-05-17 | 惠氏公司 | 用于治疗rage相关病症的组合物和方法 |
| DE10244202A1 (de) * | 2002-09-23 | 2004-03-25 | Alstom (Switzerland) Ltd. | Elektrische Maschine mit einem Stator mit gekühlten Wicklungsstäben |
| JP4914209B2 (ja) * | 2003-03-14 | 2012-04-11 | ワイス | ヒトil−21受容体に対する抗体および該抗体の使用 |
| US20050048617A1 (en) * | 2003-08-18 | 2005-03-03 | Medimmune, Inc. | Humanization of antibodies |
| JP2007504247A (ja) * | 2003-09-05 | 2007-03-01 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク | 糸球体損傷を治療するためのrageに関連した方法および組成物 |
| KR100570422B1 (ko) * | 2003-10-16 | 2006-04-11 | 한미약품 주식회사 | 대장균 분비서열을 이용하여 항체 단편을 분비·생산하는 발현벡터 및 이를 이용하여 항체 단편을 대량 생산하는 방법 |
| AU2007226863A1 (en) * | 2006-03-21 | 2007-09-27 | Wyeth | Methods for preventing and treating amyloidogenic diseases |
-
2007
- 2007-03-21 AU AU2007226863A patent/AU2007226863A1/en not_active Abandoned
- 2007-03-21 WO PCT/US2007/064568 patent/WO2007109747A2/en not_active Ceased
- 2007-03-21 US US11/689,480 patent/US20070286858A1/en not_active Abandoned
- 2007-03-21 AU AU2007226861A patent/AU2007226861A1/en not_active Abandoned
- 2007-03-21 JP JP2009501725A patent/JP2009529920A/ja active Pending
- 2007-03-21 WO PCT/US2007/064571 patent/WO2007109749A2/en not_active Ceased
- 2007-03-21 EP EP07759060A patent/EP2004694A2/en not_active Withdrawn
- 2007-03-21 RU RU2008134135/13A patent/RU2008134135A/ru not_active Application Discontinuation
- 2007-03-21 KR KR1020087025473A patent/KR20080110833A/ko not_active Withdrawn
- 2007-03-21 US US11/689,501 patent/US20070253950A1/en not_active Abandoned
- 2007-03-21 MX MX2008011933A patent/MX2008011933A/es unknown
- 2007-03-21 MX MX2008012023A patent/MX2008012023A/es not_active Application Discontinuation
- 2007-03-21 CA CA002646643A patent/CA2646643A1/en not_active Abandoned
- 2007-03-21 RU RU2008137764/13A patent/RU2008137764A/ru not_active Application Discontinuation
- 2007-03-21 EP EP07759057A patent/EP2001907A2/en not_active Withdrawn
- 2007-03-21 BR BRPI0708998-8A patent/BRPI0708998A2/pt not_active IP Right Cessation
- 2007-03-21 JP JP2009501727A patent/JP2009530423A/ja not_active Withdrawn
- 2007-03-21 CA CA002638755A patent/CA2638755A1/en not_active Abandoned
- 2007-03-21 BR BRPI0708970-8A patent/BRPI0708970A2/pt not_active IP Right Cessation
- 2007-03-21 KR KR1020087025056A patent/KR20080113236A/ko not_active Withdrawn
-
2008
- 2008-08-29 NO NO20083720A patent/NO20083720L/no not_active Application Discontinuation
- 2008-09-19 EC EC2008008750A patent/ECSP088750A/es unknown
- 2008-09-19 CR CR10297A patent/CR10297A/es not_active Application Discontinuation
- 2008-09-19 CR CR10298A patent/CR10298A/es not_active Application Discontinuation
- 2008-09-23 NO NO20084039A patent/NO20084039L/no not_active Application Discontinuation
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