JP2009529915A - ガストリン物質に対して特異的なヒト抗体および方法 - Google Patents

ガストリン物質に対して特異的なヒト抗体および方法 Download PDF

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Publication number
JP2009529915A
JP2009529915A JP2009501410A JP2009501410A JP2009529915A JP 2009529915 A JP2009529915 A JP 2009529915A JP 2009501410 A JP2009501410 A JP 2009501410A JP 2009501410 A JP2009501410 A JP 2009501410A JP 2009529915 A JP2009529915 A JP 2009529915A
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JP
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antibody
amino acid
acid sequence
light chain
antibodies
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JP2009501410A
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Japanese (ja)
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JP2009529915A5 (https=
Inventor
リンダ マシャート
マリナ ロエル
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ゾーマ テクノロジー リミテッド
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Publication of JP2009529915A5 publication Critical patent/JP2009529915A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2009501410A 2006-03-20 2006-12-13 ガストリン物質に対して特異的なヒト抗体および方法 Pending JP2009529915A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78450106P 2006-03-20 2006-03-20
PCT/US2006/047840 WO2007111661A2 (en) 2006-03-20 2006-12-13 Human antibodies specific for gastrin materials and methods

Publications (2)

Publication Number Publication Date
JP2009529915A true JP2009529915A (ja) 2009-08-27
JP2009529915A5 JP2009529915A5 (https=) 2011-02-03

Family

ID=38541569

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009501410A Pending JP2009529915A (ja) 2006-03-20 2006-12-13 ガストリン物質に対して特異的なヒト抗体および方法

Country Status (4)

Country Link
US (1) US8278421B2 (https=)
EP (1) EP2010569A4 (https=)
JP (1) JP2009529915A (https=)
WO (1) WO2007111661A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013511996A (ja) * 2009-11-30 2013-04-11 バイオテスト・アクチエンゲゼルシヤフト 疾患を治療するための剤
US9334325B2 (en) 2008-03-13 2016-05-10 Biotest Ag Method for treating psoriasis
US9512226B2 (en) 2008-03-13 2016-12-06 Biotest Ag Agent for treating disease
US9550831B2 (en) 2008-03-13 2017-01-24 Biotest Ag Method for treating psoriasis

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* Cited by examiner, † Cited by third party
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CA2712432C (en) * 2008-01-29 2018-09-25 Ablynx N.V. Methods to stabilize single variable domains
WO2011139375A1 (en) * 2010-05-06 2011-11-10 Ludwig Institute For Cancer Research Ltd Antibodies directed against carbonic anhydrase ix and methods and uses thereof
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
JP6053256B2 (ja) 2011-03-25 2016-12-27 ピーエスフォー ルクスコ エスエイアールエルＰＳ４ Ｌｕｘｃｏ Ｓ．ａ．ｒ．ｌ． 半導体チップ及びその製造方法、並びに半導体装置
KR102197478B1 (ko) * 2015-12-31 2021-01-04 프로가스트린 에 캔서스 에스.에이 알.엘. 식도암을 검출 및 치료하기 위한 조성물 및 방법
US20240018264A1 (en) * 2015-12-31 2024-01-18 Progastrine Et Cancers S.À R.L. Compositions and methods for detecting and treating ovarian cancer
US20200140851A1 (en) * 2016-08-23 2020-05-07 The Scripps Research Institute Methods and Compositions Related to In Vivo Selection of Functional Molecules
EP3568468A4 (en) * 2017-01-12 2020-12-30 Eureka Therapeutics, Inc. RECOMBINATION PRODUCTS TARGETING PEPTIDE HISTONE H3 / MHC COMPLEXES AND THEIR USES
CN110702926A (zh) * 2019-09-18 2020-01-17 太原瑞盛生物科技有限公司 一种胃泌素g17检测试剂盒及其制备方法
CN111458523A (zh) * 2020-04-07 2020-07-28 上海萨迦生物科技有限公司 胃泌素-17检测试剂盒及其制备方法和检测应用方法
CN118126177A (zh) * 2023-11-22 2024-06-04 艾维可生物科技有限公司 抗成熟型胃泌素17的单克隆抗体及其应用

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2005095459A2 (en) * 2004-03-29 2005-10-13 Receptor Biologix, Inc. Monoclonal antibodies to gastrin hormone

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9334325B2 (en) 2008-03-13 2016-05-10 Biotest Ag Method for treating psoriasis
US9512226B2 (en) 2008-03-13 2016-12-06 Biotest Ag Agent for treating disease
US9550831B2 (en) 2008-03-13 2017-01-24 Biotest Ag Method for treating psoriasis
JP2013511996A (ja) * 2009-11-30 2013-04-11 バイオテスト・アクチエンゲゼルシヤフト 疾患を治療するための剤
US9995733B2 (en) 2009-11-30 2018-06-12 Biotest Ag Agents for treating disease

Also Published As

Publication number Publication date
US20090311257A1 (en) 2009-12-17
EP2010569A2 (en) 2009-01-07
WO2007111661A2 (en) 2007-10-04
WO2007111661A3 (en) 2009-03-05
US8278421B2 (en) 2012-10-02
EP2010569A4 (en) 2009-09-09

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