JP2009529561A - ニコチンの速やかな放出をもたらす安定なロゼンジ組成物 - Google Patents
ニコチンの速やかな放出をもたらす安定なロゼンジ組成物Info
- Publication number
- JP2009529561A JP2009529561A JP2008558730A JP2008558730A JP2009529561A JP 2009529561 A JP2009529561 A JP 2009529561A JP 2008558730 A JP2008558730 A JP 2008558730A JP 2008558730 A JP2008558730 A JP 2008558730A JP 2009529561 A JP2009529561 A JP 2009529561A
- Authority
- JP
- Japan
- Prior art keywords
- nicotine
- use according
- composition
- weight
- cellulose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- 239000000203 mixture Substances 0.000 title claims abstract description 147
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- SERLAGPUMNYUCK-DCUALPFSSA-N 1-O-alpha-D-glucopyranosyl-D-mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 claims description 3
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- AIBWPBUAKCMKNS-PPHPATTJSA-N 2-hydroxybenzoic acid;3-[(2s)-1-methylpyrrolidin-2-yl]pyridine Chemical compound OC(=O)C1=CC=CC=C1O.CN1CCC[C@H]1C1=CC=CN=C1 AIBWPBUAKCMKNS-PPHPATTJSA-N 0.000 claims description 2
- MQWJVKLIBZWVEL-XRIOVQLTSA-N 3-[(2s)-1-methylpyrrolidin-2-yl]pyridine;dihydrochloride Chemical compound Cl.Cl.CN1CCC[C@H]1C1=CC=CN=C1 MQWJVKLIBZWVEL-XRIOVQLTSA-N 0.000 claims description 2
- HDJBTCAJIMNXEW-PPHPATTJSA-N 3-[(2s)-1-methylpyrrolidin-2-yl]pyridine;hydrochloride Chemical compound Cl.CN1CCC[C@H]1C1=CC=CN=C1 HDJBTCAJIMNXEW-PPHPATTJSA-N 0.000 claims description 2
- YHBIGBYIUMCLJS-UHFFFAOYSA-N 5-fluoro-1,3-benzothiazol-2-amine Chemical compound FC1=CC=C2SC(N)=NC2=C1 YHBIGBYIUMCLJS-UHFFFAOYSA-N 0.000 claims description 2
- 108010011485 Aspartame Proteins 0.000 claims description 2
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- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 claims description 2
- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 claims description 2
- 206010057852 Nicotine dependence Diseases 0.000 claims description 2
- 229910019142 PO4 Inorganic materials 0.000 claims description 2
- 208000025569 Tobacco Use disease Diseases 0.000 claims description 2
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 2
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- 235000010385 ascorbyl palmitate Nutrition 0.000 claims description 2
- 239000000605 aspartame Substances 0.000 claims description 2
- 235000010357 aspartame Nutrition 0.000 claims description 2
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 2
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- 150000001860 citric acid derivatives Chemical class 0.000 claims description 2
- 239000003086 colorant Substances 0.000 claims description 2
- 239000000796 flavoring agent Substances 0.000 claims description 2
- 235000019634 flavors Nutrition 0.000 claims description 2
- 125000003630 glycyl group Chemical class [H]N([H])C([H])([H])C(*)=O 0.000 claims description 2
- 229940041616 menthol Drugs 0.000 claims description 2
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 2
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- 235000019204 saccharin Nutrition 0.000 claims description 2
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 claims description 2
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- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 claims description 2
- 235000010378 sodium ascorbate Nutrition 0.000 claims description 2
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 claims description 2
- 229960005055 sodium ascorbate Drugs 0.000 claims description 2
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 claims description 2
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- FGAFEHZTRRYNDF-UHFFFAOYSA-L zinc;3-(1-methylpyrrolidin-2-yl)pyridine;dichloride Chemical compound [Cl-].[Cl-].[Zn+2].CN1CCCC1C1=CC=CN=C1 FGAFEHZTRRYNDF-UHFFFAOYSA-L 0.000 claims description 2
- BRTHFWPGJMGHIV-UHFFFAOYSA-L zinc;3-(1-methylpyrrolidin-2-yl)pyridine;dichloride;hydrate Chemical compound O.[Cl-].[Cl-].[Zn+2].CN1CCCC1C1=CC=CN=C1 BRTHFWPGJMGHIV-UHFFFAOYSA-L 0.000 claims description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 2
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- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000035909 sensory irritation Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000012430 stability testing Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000000844 transformation Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/10—Chewing gum characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Addiction (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Confectionery (AREA)
- Manufacture Of Tobacco Products (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78290306P | 2006-03-16 | 2006-03-16 | |
| DKPA200600375 | 2006-03-16 | ||
| PCT/EP2007/002345 WO2007104575A2 (en) | 2006-03-16 | 2007-03-16 | Stable lozenge compositions providing rapid release of nicotine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009529561A true JP2009529561A (ja) | 2009-08-20 |
| JP2009529561A5 JP2009529561A5 (enExample) | 2010-05-06 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008558730A Withdrawn JP2009529561A (ja) | 2006-03-16 | 2007-03-16 | ニコチンの速やかな放出をもたらす安定なロゼンジ組成物 |
| JP2008558729A Pending JP2009529343A (ja) | 2006-03-16 | 2007-03-16 | ニコチンの迅速放出を提供するチューインガム組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008558729A Pending JP2009529343A (ja) | 2006-03-16 | 2007-03-16 | ニコチンの迅速放出を提供するチューインガム組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20100061940A1 (enExample) |
| EP (2) | EP1998754A2 (enExample) |
| JP (2) | JP2009529561A (enExample) |
| AU (2) | AU2007224585A1 (enExample) |
| CA (2) | CA2657932A1 (enExample) |
| WO (2) | WO2007104575A2 (enExample) |
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| DK1803443T3 (en) | 2002-12-20 | 2019-02-25 | Niconovum Ab | Nicotine-containing particulate material with a crystalline cellulose |
| US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
| CA2646942C (en) | 2006-03-16 | 2014-07-29 | Modoral Brands Inc. | Improved snuff composition |
| US8642016B2 (en) | 2006-07-21 | 2014-02-04 | Jsrnti, Llc | Medicinal delivery system, and related methods |
| ES2521494T3 (es) | 2007-04-02 | 2014-11-12 | Parkinson's Institute | Métodos y composiciones para la reducción de los efectos secundarios de tratamientos terapéuticos |
| GB2468424B (en) * | 2007-04-02 | 2011-11-09 | Parkinson S Inst | Methods and compositions for reduction of side effects of therapeutic treatments |
| US20100260690A1 (en) * | 2007-09-18 | 2010-10-14 | Arne Kristensen | Stable chewing gum compositions comprising maltitol and providing rapid release of nicotine |
| SI2280687T1 (sl) | 2008-03-26 | 2019-09-30 | Stichting Sanammad | Sestavki za žvečilni gumi, ki vsebujejo kanabinoide |
| CL2009001025A1 (es) | 2008-05-01 | 2010-09-24 | Smithkline Beecham Corp | Composicion de pastilla para chupar que comprende: a) un granulo patron con al menos: un agente tampon alcalino, un modificador de la disolucion y una carga, b) un principio activo de nicotina definido extragranular y al menos un agente tampon alcalino; procedimiento de preparacion; util para eliminar o reducir el uso de tabaco. |
| ES2529297T3 (es) * | 2008-05-21 | 2015-02-18 | Novartis Ag | Chicles prensables que comprenden nicotina y un agente tamponador |
| US8833378B2 (en) | 2008-09-17 | 2014-09-16 | Niconovum Ab | Process for preparing snuff composition |
| US8343533B2 (en) * | 2009-09-24 | 2013-01-01 | Mcneil-Ppc, Inc. | Manufacture of lozenge product with radiofrequency |
| MX2012009586A (es) * | 2010-02-18 | 2012-09-12 | Jatin Vasant Thakkar | Patillas de gelatina blanda con nicotina. |
| US8952038B2 (en) | 2010-03-26 | 2015-02-10 | Philip Morris Usa Inc. | Inhibition of undesired sensory effects by the compound camphor |
| US20110268809A1 (en) | 2010-04-28 | 2011-11-03 | Paul Andrew Brinkley | Nicotine-Containing Pharmaceutical Compositions |
| US20110274628A1 (en) | 2010-05-07 | 2011-11-10 | Borschke August J | Nicotine-containing pharmaceutical compositions |
| US20130017259A1 (en) | 2011-07-06 | 2013-01-17 | The Parkinson's Institute | Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients |
| US9474303B2 (en) | 2011-09-22 | 2016-10-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US9084439B2 (en) | 2011-09-22 | 2015-07-21 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US9629392B2 (en) | 2011-09-22 | 2017-04-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US20130078307A1 (en) | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
| US9907748B2 (en) | 2011-10-21 | 2018-03-06 | Niconovum Usa, Inc. | Excipients for nicotine-containing therapeutic compositions |
| CN102754908B (zh) | 2012-01-20 | 2015-06-10 | 奥驰亚客户服务公司 | 口腔用烟草产品 |
| US9854831B2 (en) | 2012-01-20 | 2018-01-02 | Altria Client Services Llc | Oral product |
| WO2013109961A1 (en) | 2012-01-20 | 2013-07-25 | Altria Client Services Inc. | Oral product |
| CN103040090B (zh) | 2012-01-20 | 2016-03-30 | 奥驰亚客户服务公司 | 脱除烟草的口腔用产品 |
| CN102754907B (zh) | 2012-01-20 | 2015-06-24 | 奥驰亚客户服务公司 | 口腔用产品 |
| CN103039688B (zh) | 2012-01-20 | 2016-01-06 | 奥驰亚客户服务公司 | 口腔用产品 |
| US12285025B2 (en) | 2012-02-10 | 2025-04-29 | R.J. Reynolds Tobacco Company | Multi-layer smokeless tobacco composition |
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| US9044035B2 (en) | 2012-04-17 | 2015-06-02 | R.J. Reynolds Tobacco Company | Remelted ingestible products |
| US9339058B2 (en) | 2012-04-19 | 2016-05-17 | R. J. Reynolds Tobacco Company | Method for producing microcrystalline cellulose from tobacco and related tobacco product |
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| AR096223A1 (es) | 2013-05-10 | 2015-12-16 | Glaxosmithkline Llc | Pastilla de nicotina para administración oral |
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| CN103549646B (zh) * | 2013-11-11 | 2016-03-02 | 云南烟草科学研究院 | 含烟草超微粉末的口崩片型无烟烟草制品及其制备方法 |
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| US20170172995A1 (en) * | 2015-09-08 | 2017-06-22 | Venkateswara Rao Repaka | Pharmaceutical compositions of Nicotine and process for preparation thereof |
| US10869497B2 (en) | 2015-09-08 | 2020-12-22 | R.J. Reynolds Tobacco Company | High-pressure cold pasteurization of tobacco material |
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| PL4338735T3 (pl) | 2015-11-25 | 2026-05-11 | R. J. Reynolds Tobacco Company | Kompleksy soli, kokryształów i kokryształów soli nikotyny |
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| US20170165252A1 (en) | 2015-12-10 | 2017-06-15 | Niconovum Usa Inc. | Protein-enriched therapeutic composition |
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| JP2020513740A (ja) * | 2016-12-30 | 2020-05-21 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | ニコチンおよびセルロース含有シート |
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| CA3101966A1 (en) | 2018-05-29 | 2019-12-05 | Morningside Venture Investments Limited | Drug delivery methods and systems |
| EP3807260B1 (en) | 2018-06-15 | 2024-09-18 | R. J. Reynolds Tobacco Company | Purification of nicotine |
| US12397141B2 (en) | 2018-11-16 | 2025-08-26 | Morningside Venture Investments Limited | Thermally regulated transdermal drug delivery system |
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| US11672862B2 (en) | 2019-12-09 | 2023-06-13 | Nicoventures Trading Limited | Oral products with reduced irritation |
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| US12439949B2 (en) | 2019-12-09 | 2025-10-14 | Nicoventures Trading Limited | Oral compositions with reduced water activity |
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| US12439952B2 (en) | 2019-12-09 | 2025-10-14 | Nicoventures Trading Limited | Moist oral compositions |
| US11793230B2 (en) | 2019-12-09 | 2023-10-24 | Nicoventures Trading Limited | Oral products with improved binding of active ingredients |
| US11872231B2 (en) | 2019-12-09 | 2024-01-16 | Nicoventures Trading Limited | Moist oral product comprising an active ingredient |
| US11883527B2 (en) | 2019-12-09 | 2024-01-30 | Nicoventures Trading Limited | Oral composition and method of manufacture |
| US11889856B2 (en) | 2019-12-09 | 2024-02-06 | Nicoventures Trading Limited | Oral foam composition |
| US12520867B2 (en) | 2019-12-09 | 2026-01-13 | Nicoventures Trading Limited | Buffered oral compositions |
| JP2023504756A (ja) | 2019-12-09 | 2023-02-06 | ニコベンチャーズ トレーディング リミテッド | カンナビノイドを含む口腔用製品 |
| US12171872B2 (en) | 2019-12-09 | 2024-12-24 | Nicoventures Trading Limited | Oral compositions and methods of manufacture |
| US12599160B2 (en) | 2019-12-09 | 2026-04-14 | Nicoventures Trading Limited | Lipid-containing oral composition |
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| EP4304568A1 (en) | 2021-03-09 | 2024-01-17 | Nicoventures Trading Limited | Oral products and methods of manufacture |
| US20220354785A1 (en) | 2021-04-22 | 2022-11-10 | Nicoventures Trading Limited | Oral lozenge products |
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| EP4408183A1 (en) | 2021-09-30 | 2024-08-07 | Nicoventures Trading Limited | Oral product with a basic amine and an ion pairing agent |
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| GB202214771D0 (en) | 2022-10-07 | 2022-11-23 | Nicoventures Trading Ltd | Oral product |
| JP2025533130A (ja) | 2022-10-07 | 2025-10-03 | ニコベンチャーズ トレーディング リミテッド | 経口製品 |
| GB202214775D0 (en) | 2022-10-07 | 2022-11-23 | Nicoventures Trading Ltd | Oral product |
| GB202214803D0 (en) | 2022-10-07 | 2022-11-23 | Nicoventures Trading Ltd | Oral product |
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| EP4672985A1 (en) | 2023-02-28 | 2026-01-07 | Nicoventures Trading Limited | Caffeine-containing oral product |
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| GB8615676D0 (en) * | 1986-06-26 | 1986-07-30 | Stoppers Co Ltd | Nicotine containing lozenge |
| US5488962A (en) * | 1990-10-10 | 1996-02-06 | Perfetti, S.P.A. | Chewing gum which is a substitute for tobacco smoke |
| US5549906A (en) * | 1993-07-26 | 1996-08-27 | Pharmacia Ab | Nicotine lozenge and therapeutic method for smoking cessation |
| US5362496A (en) * | 1993-08-04 | 1994-11-08 | Pharmetrix Corporation | Method and therapeutic system for smoking cessation |
| SE0102197D0 (sv) * | 2001-06-20 | 2001-06-20 | Pharmacia Ab | New product and use and manufacture thereof |
| US20040101543A1 (en) * | 2002-03-22 | 2004-05-27 | John Liu | Nicotine-containing oral dosage form |
| DK1803443T3 (en) * | 2002-12-20 | 2019-02-25 | Niconovum Ab | Nicotine-containing particulate material with a crystalline cellulose |
| SI1617823T1 (sl) * | 2003-01-24 | 2019-07-31 | Nicachet Ab | Vrečka, ki obsega nikotinski sestavek za transmukozno dajanje |
| ES2321721T3 (es) * | 2003-09-08 | 2009-06-10 | Mcneil Ab | Formulaciones de nicotina y uso de las mismas. |
| ATE439839T1 (de) * | 2003-12-02 | 2009-09-15 | Fertin Pharma As | Nikotin-abgabeprodukt und herstellungsverfahren |
| WO2006000233A1 (en) * | 2004-06-29 | 2006-01-05 | Fertin Pharma A/S | Tobacco alkaloid containing chewing gum |
-
2007
- 2007-03-16 JP JP2008558730A patent/JP2009529561A/ja not_active Withdrawn
- 2007-03-16 AU AU2007224585A patent/AU2007224585A1/en not_active Abandoned
- 2007-03-16 AU AU2007224586A patent/AU2007224586A1/en not_active Abandoned
- 2007-03-16 US US12/225,260 patent/US20100061940A1/en not_active Abandoned
- 2007-03-16 WO PCT/EP2007/002345 patent/WO2007104575A2/en not_active Ceased
- 2007-03-16 CA CA002657932A patent/CA2657932A1/en not_active Abandoned
- 2007-03-16 JP JP2008558729A patent/JP2009529343A/ja active Pending
- 2007-03-16 CA CA002646230A patent/CA2646230A1/en not_active Abandoned
- 2007-03-16 WO PCT/EP2007/002344 patent/WO2007104574A2/en not_active Ceased
- 2007-03-16 EP EP07711967A patent/EP1998754A2/en not_active Withdrawn
- 2007-03-16 EP EP07723324A patent/EP1998755A2/en not_active Withdrawn
- 2007-09-16 US US12/226,273 patent/US20100004294A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009529343A (ja) | 2009-08-20 |
| EP1998754A2 (en) | 2008-12-10 |
| WO2007104574A2 (en) | 2007-09-20 |
| CA2646230A1 (en) | 2007-09-20 |
| WO2007104575A3 (en) | 2008-01-10 |
| US20100061940A1 (en) | 2010-03-11 |
| AU2007224586A1 (en) | 2007-09-20 |
| WO2007104575A2 (en) | 2007-09-20 |
| EP1998755A2 (en) | 2008-12-10 |
| US20100004294A1 (en) | 2010-01-07 |
| CA2657932A1 (en) | 2007-09-20 |
| AU2007224585A1 (en) | 2007-09-20 |
| WO2007104574A3 (en) | 2008-01-10 |
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