JP2009529049A - 神経障害の治療のためのメリダマイシン類似体 - Google Patents
神経障害の治療のためのメリダマイシン類似体 Download PDFInfo
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- JP2009529049A JP2009529049A JP2008558346A JP2008558346A JP2009529049A JP 2009529049 A JP2009529049 A JP 2009529049A JP 2008558346 A JP2008558346 A JP 2008558346A JP 2008558346 A JP2008558346 A JP 2008558346A JP 2009529049 A JP2009529049 A JP 2009529049A
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- alkyl
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- heterocyclyl
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Classifications
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- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
Landscapes
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- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77994006P | 2006-03-07 | 2006-03-07 | |
| PCT/US2007/005645 WO2007103347A1 (en) | 2006-03-07 | 2007-03-05 | Meridamycin analogues for the treatment of neurodegenerative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009529049A true JP2009529049A (ja) | 2009-08-13 |
| JP2009529049A5 JP2009529049A5 (enExample) | 2011-04-21 |
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| JP2008558346A Pending JP2009529049A (ja) | 2006-03-07 | 2007-03-05 | 神経障害の治療のためのメリダマイシン類似体 |
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| EP (1) | EP1991551A1 (enExample) |
| JP (1) | JP2009529049A (enExample) |
| KR (1) | KR20080099317A (enExample) |
| CN (1) | CN101426796A (enExample) |
| AR (1) | AR059738A1 (enExample) |
| AU (1) | AU2007223962A1 (enExample) |
| BR (1) | BRPI0708611A2 (enExample) |
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| CR (1) | CR10272A (enExample) |
| EC (1) | ECSP088718A (enExample) |
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| TW (1) | TW200804400A (enExample) |
| WO (1) | WO2007103347A1 (enExample) |
| ZA (1) | ZA200807678B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP1828203A2 (en) * | 2004-12-20 | 2007-09-05 | Wyeth | Rapamycin derivatives and the uses thereof in the treatment of neurological disorders |
| RU2394036C2 (ru) * | 2004-12-20 | 2010-07-10 | Вайет | Аналоги рапамицина и их применение при лечении неврологических, пролиферативных и воспалительных заболеваний |
Citations (3)
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|---|---|---|---|---|
| WO2005085257A1 (en) * | 2004-03-02 | 2005-09-15 | Wyeth | Macrolides and methods for producing same |
| WO2005084673A1 (en) * | 2004-03-02 | 2005-09-15 | Wyeth | Non-immunosuppressive immunophilin ligands as neuroprotective and/or neuroregenerative agents |
| WO2005121327A2 (en) * | 2004-06-03 | 2005-12-22 | Wyeth | Biosynthetic gene cluster for the production of a complex polyketide |
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|---|---|---|---|---|
| GB9302016D0 (en) | 1993-02-02 | 1993-03-17 | Sandoz Ltd | Compounds |
| GB9318144D0 (en) | 1993-09-01 | 1993-10-20 | Sandoz Ltd | Organic compounds |
| EP0729471A1 (en) | 1993-11-19 | 1996-09-04 | Abbott Laboratories | Semisynthetic analogs of rapamycin (macrolides) being immunomodulators |
| US7595187B2 (en) * | 2004-11-12 | 2009-09-29 | Wyeth | Elaiophylin biosynthetic gene cluster |
| EP1828203A2 (en) | 2004-12-20 | 2007-09-05 | Wyeth | Rapamycin derivatives and the uses thereof in the treatment of neurological disorders |
| RU2394036C2 (ru) | 2004-12-20 | 2010-07-10 | Вайет | Аналоги рапамицина и их применение при лечении неврологических, пролиферативных и воспалительных заболеваний |
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2007
- 2007-03-05 JP JP2008558346A patent/JP2009529049A/ja active Pending
- 2007-03-05 WO PCT/US2007/005645 patent/WO2007103347A1/en not_active Ceased
- 2007-03-05 MX MX2008011312A patent/MX2008011312A/es not_active Application Discontinuation
- 2007-03-05 CN CNA2007800078343A patent/CN101426796A/zh active Pending
- 2007-03-05 RU RU2008132779/04A patent/RU2008132779A/ru not_active Application Discontinuation
- 2007-03-05 EP EP07752355A patent/EP1991551A1/en not_active Withdrawn
- 2007-03-05 CA CA002643350A patent/CA2643350A1/en not_active Abandoned
- 2007-03-05 KR KR1020087021820A patent/KR20080099317A/ko not_active Withdrawn
- 2007-03-05 TW TW096107510A patent/TW200804400A/zh unknown
- 2007-03-05 US US11/713,972 patent/US7745457B2/en not_active Expired - Fee Related
- 2007-03-05 AR ARP070100899A patent/AR059738A1/es unknown
- 2007-03-05 BR BRPI0708611-3A patent/BRPI0708611A2/pt not_active Application Discontinuation
- 2007-03-05 AU AU2007223962A patent/AU2007223962A1/en not_active Abandoned
- 2007-03-09 PE PE2007000263A patent/PE20081550A1/es not_active Application Discontinuation
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2008
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- 2008-08-27 NO NO20083695A patent/NO20083695L/no not_active Application Discontinuation
- 2008-09-05 ZA ZA200807678A patent/ZA200807678B/xx unknown
- 2008-09-05 EC EC2008008718A patent/ECSP088718A/es unknown
- 2008-09-05 CR CR10272A patent/CR10272A/es not_active Application Discontinuation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005085257A1 (en) * | 2004-03-02 | 2005-09-15 | Wyeth | Macrolides and methods for producing same |
| WO2005084673A1 (en) * | 2004-03-02 | 2005-09-15 | Wyeth | Non-immunosuppressive immunophilin ligands as neuroprotective and/or neuroregenerative agents |
| WO2005121327A2 (en) * | 2004-06-03 | 2005-12-22 | Wyeth | Biosynthetic gene cluster for the production of a complex polyketide |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200807678B (en) | 2009-08-26 |
| US7745457B2 (en) | 2010-06-29 |
| AU2007223962A1 (en) | 2007-09-13 |
| KR20080099317A (ko) | 2008-11-12 |
| RU2008132779A (ru) | 2010-04-20 |
| EP1991551A1 (en) | 2008-11-19 |
| CA2643350A1 (en) | 2007-09-13 |
| CR10272A (es) | 2008-10-03 |
| MX2008011312A (es) | 2008-09-12 |
| US20070213525A1 (en) | 2007-09-13 |
| WO2007103347A1 (en) | 2007-09-13 |
| ECSP088718A (es) | 2008-10-31 |
| BRPI0708611A2 (pt) | 2011-06-07 |
| TW200804400A (en) | 2008-01-16 |
| NO20083695L (no) | 2008-10-03 |
| CN101426796A (zh) | 2009-05-06 |
| PE20081550A1 (es) | 2008-12-31 |
| IL193414A0 (en) | 2009-05-04 |
| AR059738A1 (es) | 2008-04-23 |
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