MX2008011312A - Analogos de meridamicina para el tratamiento de trastornos neurodegenerativos. - Google Patents
Analogos de meridamicina para el tratamiento de trastornos neurodegenerativos.Info
- Publication number
- MX2008011312A MX2008011312A MX2008011312A MX2008011312A MX2008011312A MX 2008011312 A MX2008011312 A MX 2008011312A MX 2008011312 A MX2008011312 A MX 2008011312A MX 2008011312 A MX2008011312 A MX 2008011312A MX 2008011312 A MX2008011312 A MX 2008011312A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- neurodegenerative disorders
- meridamycin
- analogues
- meridamycin analogues
- Prior art date
Links
- 208000015122 neurodegenerative disease Diseases 0.000 title abstract 2
- UNSKIISCJFJWTL-WIDVRGBZSA-N meridamycin Chemical class C1C(O)C(C)C(O)CC(O)CC(O)\C(C)=C\C(C)CC(C)C(O)C(/CC)=C/CC(C(\C)=C\C(C)C(C)O)OC(=O)C2CCCN2C(=O)C(=O)C2(O)C(C)CCC1O2 UNSKIISCJFJWTL-WIDVRGBZSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77994006P | 2006-03-07 | 2006-03-07 | |
| PCT/US2007/005645 WO2007103347A1 (en) | 2006-03-07 | 2007-03-05 | Meridamycin analogues for the treatment of neurodegenerative disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008011312A true MX2008011312A (es) | 2008-09-12 |
Family
ID=38289934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008011312A MX2008011312A (es) | 2006-03-07 | 2007-03-05 | Analogos de meridamicina para el tratamiento de trastornos neurodegenerativos. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7745457B2 (enExample) |
| EP (1) | EP1991551A1 (enExample) |
| JP (1) | JP2009529049A (enExample) |
| KR (1) | KR20080099317A (enExample) |
| CN (1) | CN101426796A (enExample) |
| AR (1) | AR059738A1 (enExample) |
| AU (1) | AU2007223962A1 (enExample) |
| BR (1) | BRPI0708611A2 (enExample) |
| CA (1) | CA2643350A1 (enExample) |
| CR (1) | CR10272A (enExample) |
| EC (1) | ECSP088718A (enExample) |
| IL (1) | IL193414A0 (enExample) |
| MX (1) | MX2008011312A (enExample) |
| NO (1) | NO20083695L (enExample) |
| PE (1) | PE20081550A1 (enExample) |
| RU (1) | RU2008132779A (enExample) |
| TW (1) | TW200804400A (enExample) |
| WO (1) | WO2007103347A1 (enExample) |
| ZA (1) | ZA200807678B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1828203A2 (en) * | 2004-12-20 | 2007-09-05 | Wyeth | Rapamycin derivatives and the uses thereof in the treatment of neurological disorders |
| RU2394036C2 (ru) * | 2004-12-20 | 2010-07-10 | Вайет | Аналоги рапамицина и их применение при лечении неврологических, пролиферативных и воспалительных заболеваний |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9302016D0 (en) | 1993-02-02 | 1993-03-17 | Sandoz Ltd | Compounds |
| GB9318144D0 (en) | 1993-09-01 | 1993-10-20 | Sandoz Ltd | Organic compounds |
| EP0729471A1 (en) | 1993-11-19 | 1996-09-04 | Abbott Laboratories | Semisynthetic analogs of rapamycin (macrolides) being immunomodulators |
| US20050197356A1 (en) * | 2004-03-02 | 2005-09-08 | Wyeth | Non-immunosuppressive immunophilin ligands as neuroprotective and/or neuroregenerative agents |
| BRPI0508224A (pt) | 2004-03-02 | 2007-07-17 | Wyeth Corp | composto ou um sal farmaceuticamente aceitável do mesmo, cepa de actinomiceto, isolado de uma cepa, métodos para a produção de um macrolìdeo e de um composto, produto, composição, métodos de tratamento de um mamìfero e de um distúrbio neurológico, e, uso de um composto |
| JP2008501342A (ja) | 2004-06-03 | 2008-01-24 | ワイス | 複合ポリケチドを生成するための生合成遺伝子クラスター |
| US7595187B2 (en) * | 2004-11-12 | 2009-09-29 | Wyeth | Elaiophylin biosynthetic gene cluster |
| EP1828203A2 (en) | 2004-12-20 | 2007-09-05 | Wyeth | Rapamycin derivatives and the uses thereof in the treatment of neurological disorders |
| RU2394036C2 (ru) | 2004-12-20 | 2010-07-10 | Вайет | Аналоги рапамицина и их применение при лечении неврологических, пролиферативных и воспалительных заболеваний |
-
2007
- 2007-03-05 JP JP2008558346A patent/JP2009529049A/ja active Pending
- 2007-03-05 WO PCT/US2007/005645 patent/WO2007103347A1/en not_active Ceased
- 2007-03-05 MX MX2008011312A patent/MX2008011312A/es not_active Application Discontinuation
- 2007-03-05 CN CNA2007800078343A patent/CN101426796A/zh active Pending
- 2007-03-05 RU RU2008132779/04A patent/RU2008132779A/ru not_active Application Discontinuation
- 2007-03-05 EP EP07752355A patent/EP1991551A1/en not_active Withdrawn
- 2007-03-05 CA CA002643350A patent/CA2643350A1/en not_active Abandoned
- 2007-03-05 KR KR1020087021820A patent/KR20080099317A/ko not_active Withdrawn
- 2007-03-05 TW TW096107510A patent/TW200804400A/zh unknown
- 2007-03-05 US US11/713,972 patent/US7745457B2/en not_active Expired - Fee Related
- 2007-03-05 AR ARP070100899A patent/AR059738A1/es unknown
- 2007-03-05 BR BRPI0708611-3A patent/BRPI0708611A2/pt not_active Application Discontinuation
- 2007-03-05 AU AU2007223962A patent/AU2007223962A1/en not_active Abandoned
- 2007-03-09 PE PE2007000263A patent/PE20081550A1/es not_active Application Discontinuation
-
2008
- 2008-08-12 IL IL193414A patent/IL193414A0/en unknown
- 2008-08-27 NO NO20083695A patent/NO20083695L/no not_active Application Discontinuation
- 2008-09-05 ZA ZA200807678A patent/ZA200807678B/xx unknown
- 2008-09-05 EC EC2008008718A patent/ECSP088718A/es unknown
- 2008-09-05 CR CR10272A patent/CR10272A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200807678B (en) | 2009-08-26 |
| US7745457B2 (en) | 2010-06-29 |
| AU2007223962A1 (en) | 2007-09-13 |
| KR20080099317A (ko) | 2008-11-12 |
| RU2008132779A (ru) | 2010-04-20 |
| EP1991551A1 (en) | 2008-11-19 |
| CA2643350A1 (en) | 2007-09-13 |
| CR10272A (es) | 2008-10-03 |
| US20070213525A1 (en) | 2007-09-13 |
| WO2007103347A1 (en) | 2007-09-13 |
| ECSP088718A (es) | 2008-10-31 |
| BRPI0708611A2 (pt) | 2011-06-07 |
| TW200804400A (en) | 2008-01-16 |
| NO20083695L (no) | 2008-10-03 |
| CN101426796A (zh) | 2009-05-06 |
| PE20081550A1 (es) | 2008-12-31 |
| IL193414A0 (en) | 2009-05-04 |
| AR059738A1 (es) | 2008-04-23 |
| JP2009529049A (ja) | 2009-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |