JP2009524692A5 - - Google Patents
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- Publication number
- JP2009524692A5 JP2009524692A5 JP2008552581A JP2008552581A JP2009524692A5 JP 2009524692 A5 JP2009524692 A5 JP 2009524692A5 JP 2008552581 A JP2008552581 A JP 2008552581A JP 2008552581 A JP2008552581 A JP 2008552581A JP 2009524692 A5 JP2009524692 A5 JP 2009524692A5
- Authority
- JP
- Japan
- Prior art keywords
- registered trademark
- ophthalmic formulation
- subject
- tears
- formulation according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 20
- 238000009472 formulation Methods 0.000 claims 12
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 6
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 6
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 3
- 206010013774 Dry eye Diseases 0.000 claims 3
- 229960004384 ketorolac tromethamine Drugs 0.000 claims 3
- BWHLPLXXIDYSNW-UHFFFAOYSA-N ketorolac tromethamine Chemical compound OCC(N)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 BWHLPLXXIDYSNW-UHFFFAOYSA-N 0.000 claims 3
- 241001529936 Murinae Species 0.000 claims 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 claims 2
- 229920005862 polyol Polymers 0.000 claims 2
- 150000003077 polyols Chemical class 0.000 claims 2
- MDKGKXOCJGEUJW-VIFPVBQESA-N (2s)-2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid Chemical compound C1=CC([C@@H](C(O)=O)C)=CC=C1C(=O)C1=CC=CS1 MDKGKXOCJGEUJW-VIFPVBQESA-N 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- 206010015946 Eye irritation Diseases 0.000 claims 1
- 229920002125 Sokalan® Polymers 0.000 claims 1
- 229940060237 akwa tears Drugs 0.000 claims 1
- 239000000607 artificial tear Substances 0.000 claims 1
- 229940035183 bion tears Drugs 0.000 claims 1
- 229960003655 bromfenac Drugs 0.000 claims 1
- ZBPLOVFIXSTCRZ-UHFFFAOYSA-N bromfenac Chemical compound NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1 ZBPLOVFIXSTCRZ-UHFFFAOYSA-N 0.000 claims 1
- 229960001631 carbomer Drugs 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 229960001259 diclofenac Drugs 0.000 claims 1
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 229940012356 eye drops Drugs 0.000 claims 1
- 231100000013 eye irritation Toxicity 0.000 claims 1
- 229960003898 flurbiprofen sodium Drugs 0.000 claims 1
- 229920000591 gum Polymers 0.000 claims 1
- 229940030216 hypotears Drugs 0.000 claims 1
- 229960000905 indomethacin Drugs 0.000 claims 1
- 229960004752 ketorolac Drugs 0.000 claims 1
- OZWKMVRBQXNZKK-UHFFFAOYSA-N ketorolac Chemical compound OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 OZWKMVRBQXNZKK-UHFFFAOYSA-N 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 229940099374 moisture eyes pm Drugs 0.000 claims 1
- 229940112689 moisture-eyes Drugs 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 229960001002 nepafenac Drugs 0.000 claims 1
- QEFAQIPZVLVERP-UHFFFAOYSA-N nepafenac Chemical compound NC(=O)CC1=CC=CC(C(=O)C=2C=CC=CC=2)=C1N QEFAQIPZVLVERP-UHFFFAOYSA-N 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000012188 paraffin wax Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 229940116161 refresh pm Drugs 0.000 claims 1
- GNMBMOULKUXEQF-UHFFFAOYSA-M sodium;2-(3-fluoro-4-phenylphenyl)propanoate;dihydrate Chemical compound O.O.[Na+].FC1=CC(C(C([O-])=O)C)=CC=C1C1=CC=CC=C1 GNMBMOULKUXEQF-UHFFFAOYSA-M 0.000 claims 1
- 229960004492 suprofen Drugs 0.000 claims 1
- 229940080150 systane Drugs 0.000 claims 1
- 229940036266 tears naturale Drugs 0.000 claims 1
- BJORNXNYWNIWEY-UHFFFAOYSA-N tetrahydrozoline hydrochloride Chemical compound Cl.N1CCN=C1C1C2=CC=CC=C2CCC1 BJORNXNYWNIWEY-UHFFFAOYSA-N 0.000 claims 1
- 229960003503 thera tears Drugs 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 229940028445 visine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76194506P | 2006-01-25 | 2006-01-25 | |
| PCT/US2007/061065 WO2007087609A2 (en) | 2006-01-25 | 2007-01-25 | Formulations and methods for treating dry eye |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009524692A JP2009524692A (ja) | 2009-07-02 |
| JP2009524692A5 true JP2009524692A5 (enExample) | 2011-03-17 |
Family
ID=38309951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008552581A Pending JP2009524692A (ja) | 2006-01-25 | 2007-01-25 | ドライアイのための処方物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20070254841A1 (enExample) |
| EP (1) | EP1981491A4 (enExample) |
| JP (1) | JP2009524692A (enExample) |
| AU (1) | AU2007208054A1 (enExample) |
| CA (1) | CA2636646A1 (enExample) |
| WO (1) | WO2007087609A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8512717B2 (en) | 2003-08-07 | 2013-08-20 | Allergan, Inc. | Compositions for delivery of therapeutics into the eyes and methods for making and using same |
| US8372814B2 (en) * | 2004-06-07 | 2013-02-12 | Ista Pharmaceuticals, Inc. | Ophthalmic formulations and uses thereof |
| US8748402B2 (en) | 2004-06-07 | 2014-06-10 | Bausch & Lomb Pharma Holdings Corp. | Ophthalmic formulations and uses thereof |
| US8137111B2 (en) * | 2007-06-28 | 2012-03-20 | Eye Care And Cure Pte. Ltd | Model human eye |
| AU2009202969B1 (en) * | 2009-07-23 | 2009-11-19 | Allergan, Inc. | Ketorolac tromethamine compositions for treating or preventing ocular pain |
| US7842714B2 (en) * | 2008-03-03 | 2010-11-30 | Allergan, Inc. | Ketorolac tromethamine compositions for treating ocular pain |
| US9192571B2 (en) * | 2008-03-03 | 2015-11-24 | Allergan, Inc. | Ketorolac tromethamine compositions for treating or preventing ocular pain |
| US8778999B2 (en) * | 2009-03-05 | 2014-07-15 | Insite Vision Incorporated | Non-steroidal anti-inflammatory ophthalmic compositions |
| PT2506831E (pt) | 2009-12-03 | 2014-01-08 | Alcon Res Ltd | Suspensões de nanopartículas contendo um polímero de carboxivinilo |
| SI2555770T1 (en) * | 2010-04-09 | 2018-04-30 | Allergan, Inc. | Ketorolac compositions for corneal wound healing |
| US8684743B2 (en) | 2010-07-23 | 2014-04-01 | Eye Care And Cure Pte. Ltd | Model human eye and face manikin for use therewith |
| CN102557976B (zh) * | 2010-12-15 | 2015-06-10 | 辽宁盛京制药有限公司 | 溴芬酸有机盐及其制备方法、其组合物及用途 |
| MX346312B (es) * | 2011-04-05 | 2017-03-15 | Optosolve Res & Dev Ltd | Tratamientos oftalmicos. |
| US20130023575A1 (en) * | 2011-07-22 | 2013-01-24 | Kamran Hosseini | Compositions and methods for the treatment of ocular surface allergies |
| EP3013790A1 (en) | 2013-06-27 | 2016-05-04 | Mylan Laboratories Ltd. | Process for the preparation of nepafenac |
| US9492474B2 (en) | 2013-07-10 | 2016-11-15 | Matrix Biology Institute | Compositions of hyaluronan with high elasticity and uses thereof |
| JP6373278B2 (ja) * | 2013-12-25 | 2018-08-15 | 株式会社Ｌｔｔバイオファーマ | ドライアイ治療用点眼剤 |
| US9775861B1 (en) * | 2014-09-26 | 2017-10-03 | Paul S. Jensen | Dry eye composition and method for preparing the composition |
| PT3842047T (pt) | 2015-09-24 | 2024-09-19 | Matrix Biology Inst | Composições de hialuronano de elevada elasticidade e processos para o seu uso |
| JP2024524590A (ja) * | 2021-07-09 | 2024-07-05 | コアンチョウ オキュサン オフサルミック バイオテクノロジー カンパニー リミテッド | ドライアイを治療する薬物の製造におけるロキソプロフェンナトリウムの使用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4230724A (en) * | 1979-07-16 | 1980-10-28 | Allergan Pharmaceuticals, Inc. | Method of treating vascularization of the eye with Flurbiprofen |
| US4407791A (en) * | 1981-09-28 | 1983-10-04 | Alcon Laboratories, Inc. | Ophthalmic solutions |
| US4454151A (en) * | 1982-03-22 | 1984-06-12 | Syntex (U.S.A.) Inc. | Use of pyrrolo pyrroles in treatment of ophthalmic diseases |
| DE3612537C1 (de) * | 1986-04-14 | 1987-07-16 | Dispersa Ag | Arzneimittel zur Behandlung von Entzuendungen im Auge |
| US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
| CA1325382C (en) * | 1988-01-27 | 1993-12-21 | Takahiro Ogawa | Locally administrable therapeutic composition for inflammatory disease |
| US4960799A (en) * | 1988-09-13 | 1990-10-02 | Ciba-Geigy Corporation | Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use |
| WO1994012900A1 (de) * | 1992-11-27 | 1994-06-09 | Siemens Aktiengesellschaft | Steckverbindung für einen an einen baugruppenrahmen anschliessbaren lichtleiter |
| US5475034A (en) * | 1994-06-06 | 1995-12-12 | Alcon Laboratories, Inc. | Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders |
| US5811446A (en) * | 1997-04-18 | 1998-09-22 | Cytos Pharmaceuticals Llc | Prophylactic and therapeutic methods for ocular degenerative diseases and inflammations and histidine compositions therefor |
| CN100408100C (zh) * | 1997-07-29 | 2008-08-06 | 阿尔康实验室公司 | 含半乳甘露聚糖聚合物和硼酸盐的眼用组合物 |
| US6552020B1 (en) * | 1999-07-30 | 2003-04-22 | Allergan, Inc. | Compositions including antibiotics and methods for using same |
| CA2477044A1 (en) * | 2002-02-22 | 2003-09-04 | Pharmacia Corporation | Ophthalmic formulation with gum system |
| US6828356B2 (en) * | 2002-07-29 | 2004-12-07 | Ast Products, Inc. | Preparation of ophthalmic compositions |
| US6806364B2 (en) * | 2002-07-29 | 2004-10-19 | Ast Products, Inc. | Ophthalmic compositions |
| US8129431B2 (en) * | 2003-01-21 | 2012-03-06 | Senju Pharmaceutical Co., Ltd. | Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid |
| US20050239745A1 (en) * | 2004-03-03 | 2005-10-27 | Ophthalmic Research Associates, Inc. | Novel topical ophthalmic formulations |
| WO2005101982A2 (en) * | 2004-03-24 | 2005-11-03 | Sun Pharmaceutical Industries Limited | A stable ophthalmic composition |
| PT1885336E (pt) * | 2005-05-10 | 2009-05-07 | Alcon Inc | Formulações de suspensão compreendendo um princípio activo, um tensoactivo poloxâmero ou meroxapol e um glicol, sua utilização no fabrico de um medicamento para tratamento de distúrbios oftálmicos |
-
2007
- 2007-01-25 CA CA002636646A patent/CA2636646A1/en not_active Abandoned
- 2007-01-25 AU AU2007208054A patent/AU2007208054A1/en not_active Abandoned
- 2007-01-25 US US11/698,778 patent/US20070254841A1/en not_active Abandoned
- 2007-01-25 JP JP2008552581A patent/JP2009524692A/ja active Pending
- 2007-01-25 EP EP07717416A patent/EP1981491A4/en not_active Withdrawn
- 2007-01-25 WO PCT/US2007/061065 patent/WO2007087609A2/en not_active Ceased
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