JP2009523156A - 癌の処置のためのγ線照射と組み合わせた化合物の使用 - Google Patents

癌の処置のためのγ線照射と組み合わせた化合物の使用 Download PDF

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JP2009523156A
JP2009523156A JP2008549886A JP2008549886A JP2009523156A JP 2009523156 A JP2009523156 A JP 2009523156A JP 2008549886 A JP2008549886 A JP 2008549886A JP 2008549886 A JP2008549886 A JP 2008549886A JP 2009523156 A JP2009523156 A JP 2009523156A
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JP2009523156A5 (enExample
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リカルド グラス
ホン シュー
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オンコレー アーベー
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • A61N2005/1098Enhancing the effect of the particle by an injected agent or implanted device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2008549886A 2006-01-13 2007-01-15 癌の処置のためのγ線照射と組み合わせた化合物の使用 Pending JP2009523156A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75908806P 2006-01-13 2006-01-13
US60/759,088 2006-01-13
PCT/EP2007/050363 WO2007080194A2 (en) 2006-01-13 2007-01-15 Use of tpp ii inhibitors in combination with gamma-irradiation for the treatment of cancer

Publications (2)

Publication Number Publication Date
JP2009523156A true JP2009523156A (ja) 2009-06-18
JP2009523156A5 JP2009523156A5 (enExample) 2010-02-25

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Family Applications (2)

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JP2008549886A Pending JP2009523156A (ja) 2006-01-13 2007-01-15 癌の処置のためのγ線照射と組み合わせた化合物の使用
JP2008549887A Pending JP2009523157A (ja) 2006-01-13 2007-01-15 虚血および神経変性の処置のための化合物

Family Applications After (1)

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JP2008549887A Pending JP2009523157A (ja) 2006-01-13 2007-01-15 虚血および神経変性の処置のための化合物

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US (2) US20100168038A1 (enExample)
EP (2) EP2160196A2 (enExample)
JP (2) JP2009523156A (enExample)
KR (1) KR20080085035A (enExample)
CN (1) CN101370509A (enExample)
AU (1) AU2007204314A1 (enExample)
CA (1) CA2636533A1 (enExample)
WO (2) WO2007088099A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007355462A1 (en) * 2007-06-25 2008-12-31 Oncoreg Ab TPP II inhibitors for use in the treatment of autoimmune and inflammatory diseases and transplant rejection
WO2009000297A1 (en) * 2007-06-25 2008-12-31 Oncoreg Ab Tpp ii inhibitors for use in combination with chemotherapy for the treatment of cancer
EP2772136B1 (en) * 2007-10-15 2015-09-09 The Salk Institute for Biological Studies Methods for treating a variety of diseases and conditions, and compounds useful therefor
AR079528A1 (es) 2009-12-18 2012-02-01 Idenix Pharmaceuticals Inc Inhibidores de arileno o heteroarileno 5,5-fusionado del virus de la hepatitis c
CN103189067A (zh) 2010-06-16 2013-07-03 密执安大学评议会 Wdr5与其结合配偶体的相互作用的抑制及治疗方法
AU2011348220B2 (en) * 2010-12-22 2017-09-07 The Salk Institute For Biological Studies Cyclic CRF antagonist peptides
NZ717192A (en) 2013-09-23 2019-09-27 Dr August Wolff Gmbh & Co Kg Arzneimittel Anti-inflammatory tripeptides
CA2955196A1 (en) * 2014-07-24 2016-01-28 M. Amin Khan N-methyl-d-aspartate receptor modulators and methods of making and using same
CN111603560A (zh) * 2020-06-22 2020-09-01 泉州台商投资区秋鑫茶业有限公司 茶叶γ-氨基丁酸在肿瘤放射治疗上的应用
US12036286B2 (en) 2021-03-18 2024-07-16 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06504035A (ja) * 1990-08-22 1994-05-12 トリペプ アクチボラゲット ヒト免疫不全ウィルス感染を阻止するペプチドとその使用法
JP2003506410A (ja) * 1999-08-09 2003-02-18 トリペップ アクチ ボラゲット ウィルス感染性を阻止するペプチドおよびその使用方法
JP2004531480A (ja) * 2001-02-05 2004-10-14 ノイロテル・アーゲー 神経変性疾患の処置のためのトリペプチド誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5627035A (en) * 1990-08-22 1997-05-06 Syntello Vaccine Development Ab Peptides that block human immunodeficiency virus and methods of use thereof
WO1999033801A1 (en) * 1997-12-23 1999-07-08 Institut National De La Sante Et De La Recherche Medicale (Inserm) Tripeptidyl peptidase inhibitors
WO2003024995A1 (en) * 2001-09-19 2003-03-27 Tripep Ab Molecules that block viral infectivity and methods of use thereof
US20040097422A1 (en) * 2002-06-14 2004-05-20 Karl Munger Methods of use for tripeptidyl peptidase II inhibitors as anticancer agents
US20070258973A1 (en) * 2004-01-31 2007-11-08 Bayer Healthcare Ag Diagnostics and Therapeutics for Diseases Associated with Tripeptidyl-Peptidase 2(Tpp2)

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06504035A (ja) * 1990-08-22 1994-05-12 トリペプ アクチボラゲット ヒト免疫不全ウィルス感染を阻止するペプチドとその使用法
JP2003506410A (ja) * 1999-08-09 2003-02-18 トリペップ アクチ ボラゲット ウィルス感染性を阻止するペプチドおよびその使用方法
JP2004531480A (ja) * 2001-02-05 2004-10-14 ノイロテル・アーゲー 神経変性疾患の処置のためのトリペプチド誘導体

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6012029641; J. Med. Chem. Vol.43, No.4, 2000, 664-674 *
JPN6012029642; Tetrahedron Vol.50, No.21, 1994, p.6333-46 *
JPN6012029643; Bulletin of Experimental Biology and Medicine Vol.136, No.4, 2003, p.319-322 *

Also Published As

Publication number Publication date
CA2636533A1 (en) 2007-07-19
WO2007088099A2 (en) 2007-08-09
US20090227521A1 (en) 2009-09-10
KR20080085035A (ko) 2008-09-22
WO2007080194A2 (en) 2007-07-19
US20100168038A1 (en) 2010-07-01
WO2007080194A3 (en) 2008-02-14
AU2007204314A1 (en) 2007-07-19
EP2160196A2 (en) 2010-03-10
WO2007088099A3 (en) 2007-11-08
EP1971357A2 (en) 2008-09-24
JP2009523157A (ja) 2009-06-18
CN101370509A (zh) 2009-02-18

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