CA2636533A1 - Use of tpp ii inhibitors in combination with gamma-irradiation for the treatment of cancer - Google Patents
Use of tpp ii inhibitors in combination with gamma-irradiation for the treatment of cancer Download PDFInfo
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- CA2636533A1 CA2636533A1 CA002636533A CA2636533A CA2636533A1 CA 2636533 A1 CA2636533 A1 CA 2636533A1 CA 002636533 A CA002636533 A CA 002636533A CA 2636533 A CA2636533 A CA 2636533A CA 2636533 A1 CA2636533 A1 CA 2636533A1
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- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 230000006663 ubiquitin-proteasome pathway Effects 0.000 description 1
- 125000004417 unsaturated alkyl group Chemical group 0.000 description 1
- 230000003827 upregulation Effects 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 231100000054 whole-body exposure Toxicity 0.000 description 1
- 108091005957 yellow fluorescent proteins Proteins 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
- A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75908806P | 2006-01-13 | 2006-01-13 | |
| US60/759,088 | 2006-01-13 | ||
| PCT/EP2007/050363 WO2007080194A2 (en) | 2006-01-13 | 2007-01-15 | Use of tpp ii inhibitors in combination with gamma-irradiation for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2636533A1 true CA2636533A1 (en) | 2007-07-19 |
Family
ID=36609604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002636533A Abandoned CA2636533A1 (en) | 2006-01-13 | 2007-01-15 | Use of tpp ii inhibitors in combination with gamma-irradiation for the treatment of cancer |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20100168038A1 (enExample) |
| EP (2) | EP2160196A2 (enExample) |
| JP (2) | JP2009523157A (enExample) |
| KR (1) | KR20080085035A (enExample) |
| CN (1) | CN101370509A (enExample) |
| AU (1) | AU2007204314A1 (enExample) |
| CA (1) | CA2636533A1 (enExample) |
| WO (2) | WO2007088099A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009000297A1 (en) * | 2007-06-25 | 2008-12-31 | Oncoreg Ab | Tpp ii inhibitors for use in combination with chemotherapy for the treatment of cancer |
| US20100240591A1 (en) * | 2007-06-25 | 2010-09-23 | Oncoreg Ab | Tpp ii inhibitors for use in the treatment of autoimmune and inflammatory diseases and transplant rejection |
| WO2009052116A1 (en) * | 2007-10-15 | 2009-04-23 | The Salk Institute For Biological Studies | Methods for treating a variety of diseases and conditions, and compounds useful therefor |
| US8362068B2 (en) | 2009-12-18 | 2013-01-29 | Idenix Pharmaceuticals, Inc. | 5,5-fused arylene or heteroarylene hepatitis C virus inhibitors |
| CN103189067A (zh) * | 2010-06-16 | 2013-07-03 | 密执安大学评议会 | Wdr5与其结合配偶体的相互作用的抑制及治疗方法 |
| AU2011348220B2 (en) * | 2010-12-22 | 2017-09-07 | The Salk Institute For Biological Studies | Cyclic CRF antagonist peptides |
| AU2014323008B2 (en) | 2013-09-23 | 2018-02-08 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Anti-inflammatory tripeptides |
| JP2017525684A (ja) * | 2014-07-24 | 2017-09-07 | ノーレックス インコーポレイテッド | Ｎ−メチル−ｄ−アスパラギン酸受容体モジュレーターならびにその製造方法及び使用方法 |
| CN111603560A (zh) * | 2020-06-22 | 2020-09-01 | 泉州台商投资区秋鑫茶业有限公司 | 茶叶γ-氨基丁酸在肿瘤放射治疗上的应用 |
| US12036286B2 (en) | 2021-03-18 | 2024-07-16 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9106772A (pt) * | 1990-08-22 | 1993-07-20 | Syntello Vaccin Dev Kb Companh | Processo para tratar e evitar a infeccao por virus da imunodeficiencia humana em individuos mamiferos,incluindo o homem,dispositivo atomizador,composicoes para aplicacoes topica,administracao gastrointestinal,parenteral,transdermica,para revestir equipamento medico,revestimento polimerico e peptideos |
| US5627035A (en) * | 1990-08-22 | 1997-05-06 | Syntello Vaccine Development Ab | Peptides that block human immunodeficiency virus and methods of use thereof |
| WO1999033801A1 (en) * | 1997-12-23 | 1999-07-08 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Tripeptidyl peptidase inhibitors |
| US6258932B1 (en) * | 1999-08-09 | 2001-07-10 | Tripep Ab | Peptides that block viral infectivity and methods of use thereof |
| DE10105039A1 (de) * | 2001-02-05 | 2002-08-08 | Tell Pharm Ag Hergiswil | Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
| EP1436317A1 (en) * | 2001-09-19 | 2004-07-14 | Tripep Ab | Molecules that block viral infectivity and methods of use thereof |
| US20040097422A1 (en) * | 2002-06-14 | 2004-05-20 | Karl Munger | Methods of use for tripeptidyl peptidase II inhibitors as anticancer agents |
| EP1716247A1 (en) * | 2004-01-31 | 2006-11-02 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with tripeptidyl-peptidase 2 (tpp2) |
-
2007
- 2007-01-15 KR KR1020087017003A patent/KR20080085035A/ko not_active Withdrawn
- 2007-01-15 AU AU2007204314A patent/AU2007204314A1/en not_active Abandoned
- 2007-01-15 JP JP2008549887A patent/JP2009523157A/ja active Pending
- 2007-01-15 JP JP2008549886A patent/JP2009523156A/ja active Pending
- 2007-01-15 US US12/160,787 patent/US20100168038A1/en not_active Abandoned
- 2007-01-15 US US12/160,786 patent/US20090227521A1/en not_active Abandoned
- 2007-01-15 CN CNA200780002382XA patent/CN101370509A/zh active Pending
- 2007-01-15 WO PCT/EP2007/050364 patent/WO2007088099A2/en not_active Ceased
- 2007-01-15 EP EP07726197A patent/EP2160196A2/en not_active Withdrawn
- 2007-01-15 CA CA002636533A patent/CA2636533A1/en not_active Abandoned
- 2007-01-15 WO PCT/EP2007/050363 patent/WO2007080194A2/en not_active Ceased
- 2007-01-15 EP EP07703879A patent/EP1971357A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1971357A2 (en) | 2008-09-24 |
| KR20080085035A (ko) | 2008-09-22 |
| WO2007088099A3 (en) | 2007-11-08 |
| US20090227521A1 (en) | 2009-09-10 |
| CN101370509A (zh) | 2009-02-18 |
| EP2160196A2 (en) | 2010-03-10 |
| US20100168038A1 (en) | 2010-07-01 |
| WO2007088099A2 (en) | 2007-08-09 |
| WO2007080194A3 (en) | 2008-02-14 |
| AU2007204314A1 (en) | 2007-07-19 |
| WO2007080194A2 (en) | 2007-07-19 |
| JP2009523157A (ja) | 2009-06-18 |
| JP2009523156A (ja) | 2009-06-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |