JP2009521475A5 - - Google Patents
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- Publication number
- JP2009521475A5 JP2009521475A5 JP2008547604A JP2008547604A JP2009521475A5 JP 2009521475 A5 JP2009521475 A5 JP 2009521475A5 JP 2008547604 A JP2008547604 A JP 2008547604A JP 2008547604 A JP2008547604 A JP 2008547604A JP 2009521475 A5 JP2009521475 A5 JP 2009521475A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- composition
- derivative
- sugar
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000178 monomer Substances 0.000 claims description 12
- 150000001875 compounds Chemical class 0.000 claims description 10
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 6
- 229910052739 hydrogen Inorganic materials 0.000 claims description 6
- 239000001257 hydrogen Substances 0.000 claims description 6
- 125000001424 substituent group Chemical group 0.000 claims description 6
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims 18
- 244000299461 Theobroma cacao Species 0.000 claims 6
- 235000005764 Theobroma cacao ssp. cacao Nutrition 0.000 claims 5
- 235000005767 Theobroma cacao ssp. sphaerocarpum Nutrition 0.000 claims 5
- 235000001046 cacaotero Nutrition 0.000 claims 5
- 235000013305 food Nutrition 0.000 claims 4
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims 3
- PFTAWBLQPZVEMU-UKRRQHHQSA-N (-)-epicatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-UKRRQHHQSA-N 0.000 claims 3
- PFTAWBLQPZVEMU-ZFWWWQNUSA-N (+)-epicatechin Natural products C1([C@@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-ZFWWWQNUSA-N 0.000 claims 2
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 claims 2
- 235000005487 catechin Nutrition 0.000 claims 2
- 229950001002 cianidanol Drugs 0.000 claims 2
- LPTRNLNOHUVQMS-UHFFFAOYSA-N epicatechin Natural products Cc1cc(O)cc2OC(C(O)Cc12)c1ccc(O)c(O)c1 LPTRNLNOHUVQMS-UHFFFAOYSA-N 0.000 claims 2
- 235000012734 epicatechin Nutrition 0.000 claims 2
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical class OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 claims 2
- 239000004615 ingredient Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 229930013783 (-)-epicatechin Natural products 0.000 claims 1
- 235000007355 (-)-epicatechin Nutrition 0.000 claims 1
- 206010015150 Erythema Diseases 0.000 claims 1
- 206010051246 Photodermatosis Diseases 0.000 claims 1
- 235000013361 beverage Nutrition 0.000 claims 1
- 235000019219 chocolate Nutrition 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
- 230000008845 photoaging Effects 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- HGVVOUNEGQIPMS-UHFFFAOYSA-N procyanidin Chemical class O1C2=CC(O)=CC(O)=C2C(O)C(O)C1(C=1C=C(O)C(O)=CC=1)OC1CC2=C(O)C=C(O)C=C2OC1C1=CC=C(O)C(O)=C1 HGVVOUNEGQIPMS-UHFFFAOYSA-N 0.000 claims 1
- 229920000429 procyanidin dimer Polymers 0.000 claims 1
- 150000002148 esters Chemical class 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75400605P | 2005-12-23 | 2005-12-23 | |
| PCT/US2006/049005 WO2007076006A2 (en) | 2005-12-23 | 2006-12-21 | Skin protection and improvement |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013186026A Division JP2014028823A (ja) | 2005-12-23 | 2013-09-09 | 皮膚の保護および改善 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009521475A JP2009521475A (ja) | 2009-06-04 |
| JP2009521475A5 true JP2009521475A5 (enExample) | 2010-08-12 |
Family
ID=38218664
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008547604A Pending JP2009521475A (ja) | 2005-12-23 | 2006-12-21 | 皮膚の保護および改善 |
| JP2013186026A Pending JP2014028823A (ja) | 2005-12-23 | 2013-09-09 | 皮膚の保護および改善 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013186026A Pending JP2014028823A (ja) | 2005-12-23 | 2013-09-09 | 皮膚の保護および改善 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070148107A1 (enExample) |
| EP (1) | EP2004208B1 (enExample) |
| JP (2) | JP2009521475A (enExample) |
| CN (1) | CN101374535A (enExample) |
| AU (1) | AU2006331531B2 (enExample) |
| CA (1) | CA2634127C (enExample) |
| ES (1) | ES2619157T3 (enExample) |
| WO (1) | WO2007076006A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0719542D0 (en) * | 2007-10-08 | 2007-11-14 | Barry Callebaut Ag | Use of cocoa extract |
| GB0719544D0 (en) * | 2007-10-08 | 2007-11-14 | Barry Callebaut Ag | Cocoa extract and use thereof |
| GB0719545D0 (en) * | 2007-10-08 | 2007-11-14 | Barry Callebaut Ag | Novel use of cocoa extract |
| GB0719543D0 (en) * | 2007-10-08 | 2007-11-14 | Barry Callebaut Ag | Cocoa extract and novel use thereof |
| GB0801401D0 (en) * | 2008-01-25 | 2008-03-05 | Barry Callebaut Ag | Composition |
| US20090263518A1 (en) | 2008-04-17 | 2009-10-22 | Barry Callebaut Ag | Composition and Uses Thereof |
| KR20120059451A (ko) | 2009-04-03 | 2012-06-08 | 다이아나플랜트사이언스, 아이엔씨. | 식물 세포 배양 유래 프로시아니딘의 생산 및 추출 |
| US20140242157A1 (en) * | 2009-05-05 | 2014-08-28 | Cacao Bio-Technologies, Llc | Epicatechin compositions and methods |
| CN105341355A (zh) * | 2009-10-14 | 2016-02-24 | 希乐克公司 | 从乙醇生产中产生可食用残留物 |
| CN103237457A (zh) | 2010-10-04 | 2013-08-07 | 戴安娜植物科学有限公司 | 从植物细胞培养物产生和提取原花青素 |
| CN102273708A (zh) * | 2011-06-30 | 2011-12-14 | 蔡一青 | 具有改善血管内皮系统及美白作用的功能饮料 |
| JP2017171638A (ja) * | 2016-03-25 | 2017-09-28 | 花王株式会社 | 骨強度改善剤 |
| JPWO2023058649A1 (enExample) * | 2021-10-05 | 2023-04-13 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5554645A (en) * | 1994-10-03 | 1996-09-10 | Mars, Incorporated | Antineoplastic cocoa extracts and methods for making and using the same |
| US6297273B1 (en) | 1996-04-02 | 2001-10-02 | Mars, Inc. | Use of cocoa solids having high cocoa polyphenol content in tabletting compositions and capsule filling compositions |
| US6312753B1 (en) | 1996-09-06 | 2001-11-06 | Mars, Incorporated | Cocoa components, edible products having enriched polyphenol content, methods of making same and medical uses |
| US6015913A (en) | 1996-09-06 | 2000-01-18 | Mars, Incorporated | Method for producing fat and/or solids from cocoa beans |
| US6207842B1 (en) | 1997-10-09 | 2001-03-27 | Mars Incorporated | Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives |
| DE19809304A1 (de) * | 1998-03-05 | 1999-09-09 | Merck Patent Gmbh | Formulierungen mit antiviraler Wirkung |
| EP1894566A1 (en) * | 1998-03-12 | 2008-03-05 | Mars, Incorporated | Products containing polyphenol(s) and L-arginine to stimulate nitric oxide production |
| JP3817404B2 (ja) * | 2000-02-22 | 2006-09-06 | 森永製菓株式会社 | 創傷治癒促進剤 |
| US6156912A (en) | 1999-04-09 | 2000-12-05 | Mars, Incorporated | 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation |
| US7015338B1 (en) | 1999-04-15 | 2006-03-21 | Mars Incorporated | Synthetic methods for preparing procyanidin oligomers |
| JP4082823B2 (ja) * | 1999-05-06 | 2008-04-30 | 日本メナード化粧品株式会社 | 光毒性抑制剤 |
| US6375992B1 (en) * | 2000-02-23 | 2002-04-23 | The Procter & Gamble Co. | Methods of hydrating mammalian skin comprising oral administration of a defined composition |
| CA2403691C (en) * | 2000-03-22 | 2011-02-01 | Harold H. Schmitz | The use of cocoa procyanidins combined with acetylsalicylic acid as an anti-platelet therapy |
| MXPA02009956A (es) * | 2000-04-14 | 2003-02-12 | Mars Inc | Composiciones y metodos para mejorar la salud vascular. |
| US6254898B1 (en) * | 2000-05-25 | 2001-07-03 | Protective Factors, Inc. | Nutraceutical composition for protection against solar radiation |
| US6627232B1 (en) | 2000-06-09 | 2003-09-30 | Mars Incorporated | Method for extracting cocoa procyanidins |
| IT1320080B1 (it) * | 2000-10-25 | 2003-11-18 | Giuliani Spa | Composizione per uso farmaceutico o dietetico. |
| JP4456796B2 (ja) * | 2001-09-27 | 2010-04-28 | 株式会社林原生物化学研究所 | コラーゲン産生増強剤の製造方法とその用途 |
| JP2003325135A (ja) * | 2002-05-08 | 2003-11-18 | Toyo Shinyaku:Kk | 健康食品 |
| JP2004075619A (ja) * | 2002-08-20 | 2004-03-11 | Naris Cosmetics Co Ltd | タイプ２ヘルパーｔ細胞型サイトカイン抑制剤 |
| CN1889944A (zh) * | 2003-10-10 | 2007-01-03 | 马尔斯公司 | ErbB2激酶过量表达相关疾病的治疗 |
| US20060292094A1 (en) * | 2005-06-24 | 2006-12-28 | Robert Bell | Composition and method of protection against UV irradiation |
-
2006
- 2006-12-21 CN CNA200680052794XA patent/CN101374535A/zh active Pending
- 2006-12-21 US US11/643,527 patent/US20070148107A1/en not_active Abandoned
- 2006-12-21 JP JP2008547604A patent/JP2009521475A/ja active Pending
- 2006-12-21 ES ES06848025.0T patent/ES2619157T3/es active Active
- 2006-12-21 CA CA2634127A patent/CA2634127C/en active Active
- 2006-12-21 AU AU2006331531A patent/AU2006331531B2/en active Active
- 2006-12-21 EP EP06848025.0A patent/EP2004208B1/en active Active
- 2006-12-21 WO PCT/US2006/049005 patent/WO2007076006A2/en not_active Ceased
-
2013
- 2013-09-09 JP JP2013186026A patent/JP2014028823A/ja active Pending
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