JP2009518025A - 細胞表面標的に対して結合特異性を有する二重特異性リガンドおよびその使用方法 - Google Patents

細胞表面標的に対して結合特異性を有する二重特異性リガンドおよびその使用方法 Download PDF

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JP2009518025A
JP2009518025A JP2008543894A JP2008543894A JP2009518025A JP 2009518025 A JP2009518025 A JP 2009518025A JP 2008543894 A JP2008543894 A JP 2008543894A JP 2008543894 A JP2008543894 A JP 2008543894A JP 2009518025 A JP2009518025 A JP 2009518025A
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アンジェリス，エレナ デ
ホームズ，スティーブ
トムリンソン，イアン，エム．
ホワン，エリック，イ−チュン
ホールト，ルーシー，ジェイ．
エヴェレット，クレア，イー．
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ドマンティス リミテッド
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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JP2008543894A 2005-12-06 2006-12-05 細胞表面標的に対して結合特異性を有する二重特異性リガンドおよびその使用方法 Pending JP2009518025A (ja)

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Application Number Priority Date Filing Date Title
US74299205P 2005-12-06 2005-12-06
PCT/GB2006/004565 WO2007066109A1 (en) 2005-12-06 2006-12-05 Bispecific ligands with binding specificity to cell surface targets and methods of use therefor

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JP2009518025A true JP2009518025A (ja) 2009-05-07
JP2009518025A5 JP2009518025A5 (enExample) 2010-01-07

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US (1) US20100021473A1 (enExample)
EP (1) EP1963370A1 (enExample)
JP (1) JP2009518025A (enExample)
KR (1) KR20080090414A (enExample)
CN (2) CN101379088A (enExample)
AU (1) AU2006323415A1 (enExample)
BR (1) BRPI0619460A2 (enExample)
CA (1) CA2632424A1 (enExample)
CR (1) CR10100A (enExample)
EA (1) EA200801171A1 (enExample)
MA (1) MA30020B1 (enExample)
NO (1) NO20082381L (enExample)
TW (1) TW200738750A (enExample)
WO (1) WO2007066109A1 (enExample)
ZA (1) ZA200804307B (enExample)

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JP2015521587A (ja) * 2012-06-07 2015-07-30 デューク ユニバーシティー ヒト二重特異性ＥＧＦＲｖＩＩＩ抗体結合分子
JP2019503167A (ja) * 2015-11-10 2019-02-07 ユニバーシティ・メディカル・センター・ハンブルク−エッペンドルフＵｎｉｖｅｒｓｉｔｙ Ｍｅｄｉｃａｌ Ｃｅｎｔｅｒ Ｈａｍｂｕｒｇ − Ｅｐｐｅｎｄｏｒｆ Ｃｄ３８に対する抗原結合性ポリペプチド
JP2020501513A (ja) * 2016-09-29 2020-01-23 エーイービーアイ リミテッド 治療用多標的コンストラクトおよびその使用
JP2022505445A (ja) * 2018-10-26 2022-01-14 テネオバイオ， インコーポレイテッド Ｃｄ３８に結合する重鎖抗体

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US9320792B2 (en) 2002-11-08 2016-04-26 Ablynx N.V. Pulmonary administration of immunoglobulin single variable domains and constructs thereof
US20060034845A1 (en) 2002-11-08 2006-02-16 Karen Silence Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
NZ540196A (en) 2002-11-08 2008-09-26 Ablynx Nv Camelidae antibodies against imminoglobulin E and use thereof for the treatment of allergic disorders
US20100003253A1 (en) * 2002-11-08 2010-01-07 Ablynx N.V. Single domain antibodies directed against epidermal growth factor receptor and uses therefor
AR069979A1 (es) * 2007-12-26 2010-03-03 Biotest Ag Metodo para disminuir los efectos secundarios citotoxicos y mejorar la eficacia de los inmunoconjugados
WO2009080829A1 (en) 2007-12-26 2009-07-02 Biotest Ag Agents targeting cd138 and uses thereof
MX2010007102A (es) * 2007-12-26 2011-07-01 Biotest Ag Inmunoconjugados dirigidos contra cd138 y sus usos.
US9446146B2 (en) * 2007-12-26 2016-09-20 Biotest Ag Methods and agents for improving targeting of CD138 expressing tumor cells
US8557243B2 (en) 2008-01-03 2013-10-15 The Scripps Research Institute EFGR antibodies comprising modular recognition domains
WO2009088805A2 (en) 2008-01-03 2009-07-16 The Scripps Research Institute Antibody targeting through a modular recognition domain
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